What were the top read stories on Houston energy innovation? These five articles attracted the most attention this year. Photo via Getty Images

Editor's note: As 2022 comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. In the energy capital of the world, there were dozens of energy tech stories, from most-promising energy tech startups to new cohorts of energy accelerators. Here are five Houston energy tech-focused articles that stood out to readers this year — be sure to click through to read the full story.


Investors name most promising energy tech startups at annual Houston event

The Rice Alliance for Technology and Entrepreneurship handed out awards to the founders of the most promising companies that pitched. Photo courtesy of Slyworks Photography/Rice Alliance

Nearly 100 energy tech startups pitched at the 19th annual Rice Alliance Energy Tech Venture Forum this week — and over a third of those companies are based in the Houston area.

At the conclusion of the event — which took place on Thursday, September 15, at Rice University, and included a day full of company pitches, panels, and thought leadership — 10 startups were deemed the most promising among their peers. The group was voted on by investors attending office hours ahead of the event.

The Rice Alliance for Technology and Entrepreneurship facilitated nearly 700 meetings between 70 investor groups and 90 ventures, according to the organization. The group of presenting companies included participants from Rice's Clean Energy Accelerator's first two cohorts. Read more.

Energy transition innovator shares how Houston could be a biomanufacturing hub​

Moji Karimi joins InnovationMap to discuss how Cemvita Factory has deployed its recent investment funding and what's next for the company and Houston as a whole when it comes to biomanufacturing. Photo courtesy of Cemvita

Moji Karimi and his sister Tara had the idea for a company that could transform carbon emissions and mitigate new damage to the environment. Only, it seems, they were a bit ahead of their time.

Houston-based Cemvita Factory, founded in 2017, uses synthetic biology and take carbon emissions and transform them into industrial chemicals. However, it's only been since recently that the conversation on climate change mitigation has focused on carbon utilization.

"I think people are realizing more about the importance of really focusing on carbon capture and utilization because fossil fuels are gonna be here, whether we like it or not, for a long time, so the best thing we could do is to find ways to decarbonize them," Moji Karimi, co-founder and CEO, tells InnovationMap. "There's been this focus around carbon capture and storage, and I think the next awakening is going to be utilization." Read more.

3 startups join Houston cleantech incubator

Halliburton Labs has announced its next set of clean energy tech companies. Photo courtesy of Halliburton

Three businesses have just joined Halliburton Labs, a Houston-based accelerator for clean energy startups.

The new members of Halliburton Labs are A-W Energy, a Finland-based startup whose technology converts ocean waves into energy; RedShift Energy, a Pennsylvania-based startup whose technology recovers hydrogen; and Renkube, an India-based startup whose technology aims to lower the cost of producing solar power.

Halliburton Labs says its participants enjoy access to technical expertise, mentorships, and other benefits.

“These new companies reflect our view that numerous innovations at scale are important in the evolution of energy systems. … We are eager to collaborate with these companies to help them achieve their strategic, operational, and financial milestones,” Dale Winger, managing director of Halliburton Labs, says in a news release. Read more.

Houston oil and gas company reveals details on $1B carbon capture facility

Oxy is working on a direct air carbon capture facility in the Permian Basin — and is committing to up to a $1 billion price tag for the project. Rendering via 1pointfive.com

Ramping up its investment in clean energy, Houston-based Occidental Petroleum plans to spend up to $1 billion on a facility in the Permian Basin that will pull carbon dioxide from the air.

During a March 23 investor update, executives at Occidental laid out their strategy for developing direct air carbon capture plants and carbon sequestration hubs.

Executives said Occidental’s first direct air capture facility is set to be built in the Permian Basin, a massive oil-producing region in West Texas and southeastern New Mexico. The industrial-scale facility, with an estimated price tag of $800 million to $1 billion, is on track to open in late 2024. Construction is supposed to start later this year. Read more.

How Greentown Houston accelerated the local energy transition in its inaugural year

Greentown Houston's Juliana Garaizar and Emily Reichert look back on the climatetech incubator's first year. Photos via greentownlabs.com

This Thursday, Greentown Houston officially celebrates the completion of its first year in town, as well as the impact its made in just the 365 days since its grand opening.

Emily Reichert, CEO of Greentown Labs, officially cut the ribbon on the organization's first location outside of the Boston area last Earth Day. Reichert, along with Juliana Garaizar, head of the Houston incubator and vice president of innovation, joined InnovationMap for a Q&A looking back on this past year — including what surprised them most and where members are moving in from. Read more.

The ultimate who's who of 2022 — favorite Houston Innovators Podcast guests of last year. Photos courtesy

Editor's Picks: 7 favorite Houston interviews of 2022

houston innovators podcast episode 28

Editor's note: In 2022, I recorded over 50 episodes of the Houston Innovators Podcast — a weekly discussion with a Houston innovator, startup founder, investor, and more. I've rounded up seven podcast episodes that stood out for me looking back at the year of recordings. Scroll through to see whom I selected and stream their individual episodes, and tune into the last episode of the year where I explain why I selected each guest.



Veronica Wu, founder of First Bight Ventures — Episode 119

Veronica Wu is the founder of First Bight Ventures, a VC firm focused on funding early-stage synthetic biology companies. Wu relocated from Silicon Valley to Houston to start her firm. She’s held tech positions at Apple, Tesla, and Motorola, and she says she’s not afraid to dive headfirst into a new technology she sees as promising — and that’s exactly what she’s doing in the SynBio space now and she’s betting on Houston to be a hub for it. Read more.

Armand Paradis, founder and CEO of ComboCurve — Episode 132

Houston startups saw some major funding rounds this year, and one startup that was in the midst of deploying new capital into their plans of growing and scaling was ComboCurve. Founder Armand Paradis closed a $50 million series B round earlier this year. The company has built a software platform for various verticals within the energy industry, and Paradis describes how he wants his technology to have an impact the energy transition. Read more.

John "JR" Reale, entrepreneur in residence at the Texas Medical Center — Episode 136 and 137

In June, John Reale was a guest on two episodes. He discussed his role at the Texas Medical Center’s innovation institute as well as his own early-stage venture capital firm. Reale has been a major player within the Houston Innovation ecosystem since its early days, and he has a unique perspective on Houston’s early innovation activity, including the founding of Station Houston and the rejection from Amazon for its second HQ. Read more.


Allie Danziger, founder of Ampersand — Episode 126

In March, Allie Danziger dove into the generational divide within the workforce and the Great Resignation. She founded Ampersand, a professional development tech platform that onboards interns, and upskills them on how to be successful in the workplace. Danziger is so passionate about making sure both companies and the future of the workforce are prepared to be on the same page. Read more.

Benjamin Foster, founder of Nursify — Episode 148

Benjamin Foster founded Nursery, a platform that helps connect nurses with the health care facilities that need them. While he is proud of the tool he created to help nurses find work, he strives to make the platform inclusive, educational, and supportive for these health care professionals who are burnt out from the pandemic.  Read more.

Joanna Nathan, CEO of Prana Thoracic — Episode 149

Joanna Nathan is an individual who transitioned from supporting startups at Johnson and Johnson's Center for Device Innovation, to leading a startup of her own. She shares how she came to become CEO of Prana Thoracic, a company tackling early-stage lung cancer diagnostics. She also shared her story of her own personal loss — her young son, Lionel — and how this loss drives her every day. Read more.

Natara Branch, CEO of Houston Exponential — Episode 158

Natara Branch, the new CEO of Houston Exponential, joined HX in November and jumped into the role headfirst. She is passionate about Houston, and took it upon herself to meet the Houston innovation community — and to make sure they know we're all in it together. Read more.

Innovative shoewear, luxury EV charging, and more — all this innovation and more is coming out of Houston startups. Courtesy photos

Top 5 Houston startup feature stories of 2022

year in review

Editor's note: As 2022 comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. This past year, InnovationMap featured profiles on dozens of these Houston startups — from sportstech apps and health tech companies to startups with solutions in EV tech and more. Here are five Houston startup features that stood out to readers this year — be sure to click through to read the full story.

Houston-based health tech startup is revolutionizing patient selection for clinical trials

Sieve Health is an AI cloud-based SaaS platform designed to automate and accelerate matching patients with clinical trials. Photo via Getty Images

On many occasions in her early career, Dr. Arti Bhosale, co-founder and CEO of Sieve Health, found herself frustrated with having to manually sift through thousands of digital files.

The documents, each containing the medical records of a patient seeking advanced treatment through a clinical trial, were always there to review — and there were always more to read.

Despite the tediousness of prescreening, which could take years, the idea of missing a patient and not giving them the opportunity to go through a potentially life-altering trial is what kept her going. The one she didn’t read could have slipped through the cracks and potentially not given someone care they needed.

“Those stories have stayed with me,” she says. “That’s why we developed Sieve.” Read more.

Houston startup snags prestigious grant from global health leader

Houston-based medical device and biotech startup Steradian Technologies has been recognized by the Bill and Melinda Gates Foundation. Photo by Dwight C. Andrews/Greater Houston Convention and Visitors Bureau

A female-founded biotech startup has announced that it has received a grant from the Bill & Melinda Gates Foundation.

Steradian Technologies has developed a breath-based collection device that can be used with diagnostic testing systems. Called RUMI, the device is non-invasive and fully portable and, according to a news release, costs the price of a latte.

“We are extremely honored to receive this award and be recognized by the Bill & Melinda Gates Foundation, a leader in global health. This funding will propel our work in creating deep-tech diagnostics and products to close the equity gap in global public health," says Asma Mirza, CEO and co-founder of Steradian Technologies, in the release. “The RUMI will demonstrate that advanced technology can be delivered to all areas of the world, ensuring the Global South and economically exploited regions receive access to high-fidelity diagnostics instead of solutions that are ill-suited to the environment.” Read more.

Houston sports tech startup is enhancing performance metrics for runners and athletes

Houston-based AiKYNETIX is equipping runners with high-tech tracking tools. Image courtesy of AiKYNETIX

With the Houston Marathon only five months away, a new application using human motion insights could help a runner refine their form to reach peak performance – all from the convenience of their smart phone.

While traditional treadmills are limited in training feedback and wearables are not designed to track elevation, Houston-based AiKYNETIX uses real-time technology to provide a new option for runners on treadmills.

“Runners spend a lot of time, energy and money to run better,” says Denis Akhiyarov, CEO and co-founder. “In my personal life with training for nine marathons, I’ve seen limitations with wearables, they don’t actually track running form while running. Overall, our technology tracks not only your basic parameters but it can also analyze the human running form while in motion.” Read more.

Local startup to upgrade EV charging in Houston and beyond

Houston-based Spark Spaces is looking to build out luxury spots for electric vehicle charging. Rendering courtesy of Spark Spaces

At 3 a.m. one night, just as he had many nights before, Tarun Girish found himself leaving his Houston apartment in search of an EV charger.

Once he located one, he would sit in his car for an hour and a half while his vehicle charged — with not much to do but wait.

But it was on this night he wondered if there was a way to use his previous hospitality experience to build a new kind of experience for EV drivers. He then developed his first iteration of a business plan — all while sitting in his driver’s seat.

His idea became Sparks Spaces, a startup formed in 2021 looking to shake up the EV charging game — the company aims to elevate the experience of charging electric vehicles by focusing on the space between car and charger by creating an airport lounge-type space for drivers. These EV lounges would include luxury waiting areas, clean restrooms, high-end food options, and availability to utilize them 24/7. Read more.

Houston neuroscientist turned startup founder takes steps toward comfier shoes

Steffie Tomson founded a company to prioritize comfort — without sacrificing style — for women on the go. Photo via getawaysticks.com

Two and half years ago, native Houstonian Steffie Tomson ordered $2,000 worth of shoes and sliced them all in half with a bandsaw just to see what was inside.

Tomson, a neuroscientist by trade and the founder and CEO of footwear startup Getaway Sticks, had an idea for a different kind of shoe — one that was redesigned to prioritize women’s comfort.

“I thought, ‘why can’t we start with a sneaker material and then build a heel around it?’” she tells InnovationMap. “I started just slicing everyone else’s shoes and now I’m more convinced than ever that our shoe is different.” Read more.

Impactful tech startups, Houston landing on a list of emerging startup hubs, and more news trended on InnovationMap this year. Photo via Getty Images

Looking back: Top 5 most-read Houston impact stories of 2022

year in review

Editor's note: As 2022 comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. When it came to impact — from a startup looking to reduce clothing waste and optimize used clothing shopping to Houston being named an emerging startup hub — in Houston, five stories trended among readers.

Houston tech ecosystem ranks as No. 5 in the world for emerging startup hubs

Houston's ranking on this global report improved 14 spots between now and last year. Photo via Getty Images

As a startup hub, Houston is movin’ on up.

In a new report from Startup Genome and the Global Entrepreneurship Network, Houston ranks fifth among the world’s top 100 emerging ecosystems for startups. Last year, the groups’ report put Houston at No. 19 in the same category.

Ahead of Houston on the list of the top emerging ecosystems for startups are first-ranked Detroit; second-ranked Hong Kong; third-ranked Dublin, Ireland; and fourth-ranked Minneapolis. Read more.

Houston startup seeks to simplify sustainable fashion

A Houston innovator found second-hand shopping time consuming. So, she designed a better experience. Image courtesy of Trendy Seconds

When the coronavirus pandemic started in 2020, people found themselves at home with a surplus of free time. Puzzles covered dining room tables, remnants of new hobbies were strewn across dens, TikTok dances were rehearsed, and television was binged. Maria Burgos found herself watching Netflix’s “Tidying Up with Marie Kondo,” which inspired her to clean out her closet. In practicing Kondo’s dogma of parting with items that don’t “spark joy,” Burgos uncovered a bigger issue to purge: America’s unsustainable fashion industry.

She asked herself why there wasn’t a website where she could find items in one place. “That was the genesis of Trendy Seconds,” she shares. Read more.

International botanical water company plans expansion into Houston

Amid a growing water shortage, this international company has developed an innovative way to harvest a new water source — and it's bringing it to Houston. Image via Getty Images

More than 2 million Americans don’t have access to clean drinking water, according to one study by the U.S. Water Alliance group.

To help close that water gap, international firm, Botanical Water Technologies, has plans to expand its presence in the United States with the Houston region being a strategic area to roll out the implementation of a patented water filtration technology. In addition, the group is launching a blockchain enabled trading platform with Fujitsu to help support the business.

“Water is finite,” says James Rees, chief impact officer at BWT. “Due to global growth and climate conditions, we are going to have between 20 to 30 percent less water available to us by 2025. Communities are facing issues with water infrastructure. Some communities don't have water. This is where BWT plans to come in to help.” Read more.

Q&A: How the Houston tech community can support LGBTQIA+ innovators

Tammi Wallace of the Greater Houston LGBT Chamber of Commerce is a panelist on The Ion's Pride in Tech event. Photo via LinkedIn

It's Pride Month, and the Houston tech community is celebrating its LGBTQIA+ community — as well as addressing some challenges faced within the business arena.

Wallace, who co-founded the Greater Houston LGBT Chamber of Commerce in 2016, joined InnovationMap for a quick Q&A ahead of the event. Read more.

2 Houston organizations announce strategic appointments across finance and research

Here are two of the latest updates on new appointments from two Houston organizations. Photos courtesy

Three Houston innovators have new roles they're excited about this summer. From new academia to bitcoin, here's who's moving and shaking in Houston innovation. Read more.

These five deals were the largest rounds raised by Houston startups, according to InnovationMap. Photo via Getty Images

Big deals: These were the top 5 investment rounds raised by Houston startups in 2022

year in review

Editor's note: As 2022 comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. When it came to the money raised in Houston, these five startups raised the most, according to reporting done by InnovationMap.

Houston unicorn chemicals company raises $200M series D

Solugen closed its series D funding round at $200 million. Photo via Getty Images

Houston-based Solugen has announced its latest round of investment to the tune of $200 million. The company, which reached unicorn status after its $357 million series C round last year, uses its patented Bioforge processes to produce "green" chemicals from bio-based feedstocks.

"Solugen is reimagining the chemistry of everyday life with enzymes found in nature. We make chemicals better, faster, cheaper, and without fossil fuels from right here in Houston, Texas. Whether you care about the climate, local competitiveness, or just plain old profits, we have good news: it's working," the company states in its news release. Read more.

Houston microgrid tech company announces $150 investment

Houston-based VoltaGrid provides small-scale, self-contained microgrids that can operate independently of major power grids or in tandem with other microgrids. Photo via voltagrid.com

VoltaGrid, a Bellaire-based startup that specializes in distributed power generation via microgrids, has hauled in $150 million in equity funding.

Founded in 2020, VoltaGrid provides small-scale, self-contained microgrids that can operate independently of major power grids or in tandem with other microgrids. VoltaGrid’s product consists of natural gas engines, portable energy storage, natural gas processing and grid power connectivity. Read more.

Houston company raises $138M for next-generation geothermal energy

The future of geothermal energy is here — and just got a big payday. Photo via Getty Images

Houston-based startup Fervo Energy has picked up $138 million in funding to propel its creation and operation of carbon-free power plants fueled by geothermal energy.

Fervos says the series C round will help it complete power plants in Nevada and Utah and evaluate new projects in California, Idaho, Oregon, Colorado, and New Mexico, as well as in other countries.

California-based investment firm DCVC led the round, with participation from six new investors. Read more.

Houston company closes $76M series C round to fuel its mission of reducing carbon emissions

Syzygy Plasmonics has raised a series C round of funding. Photo courtesy of Syzygy

A Houston-based company that is electrifying chemical manufacturing has closed its largest round of funding to date.

Syzygy Plasmonics closed a $76 million series C financing round led by New York-based Carbon Direct Capital. The round included participation from Aramco Ventures, Chevron Technology Ventures, LOTTE CHEMICAL, and Toyota Ventures. The company's existing investors joining the round included EVOK Innovations, The Engine, Equinor Ventures, Goose Capital, Horizons Ventures, Pan American Energy, and Sumitomo Corporation of Americas. According to a news release, Carbon Direct Capital will join Syzygy's board and serve as the series C director. Read more.

Fast-growing energy fintech startup raises $50M series B

The series B capital will allow the company to enhance its core product, while also adding on other workflows that focus on emissions and renewable energy. Image via combocurve.com

Houston-based ComboCurve announced today that it has raised $50 million through a series B funding round led by Dragoneer Investment Group and Bessemer Venture Partners.

Founded in 2017, the company is a cloud-based energy analytics and operating platform that uses sophisticated software to forecast and report on a company's energy assets, including renewables.

The series B capital will allow the company to enhance its core product, while also adding on other workflows that focus on emissions and renewable energy. Read more.


The top lifestyle innovation stories of the year included a new surfing spot coming to town. Rendering courtesy of Beach Street Development

These are Houston's top lifestyle tech and innovation articles of 2022

year in review

Editor's note: As 2022 comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. When it came to the lifestyle innovation — whether it's fit tech companies or space bartenders — in Houston, five stories trended among readers. Be sure to click through to read the full story.

Houston startup seeks to simplify sustainable fashion

A Houston innovator found second-hand shopping time consuming. So, she designed a better experience. Image courtesy of Trendy Seconds

When the coronavirus pandemic started in 2020, people found themselves at home with a surplus of free time. Puzzles covered dining room tables, remnants of new hobbies were strewn across dens, TikTok dances were rehearsed, and television was binged. Maria Burgos found herself watching Netflix’s “Tidying Up with Marie Kondo,” which inspired her to clean out her closet. In practicing Kondo’s dogma of parting with items that don’t “spark joy,” Burgos uncovered a bigger issue to purge: America’s unsustainable fashion industry.

With piles of clothing ready for a new home, Burgos searched for reliable organizations to donate her possessions. Her research led her to learn more about the negative impact the fashion industry has on the environment.

According to Slate, almost 24 billion pounds of clothes and shoes are thrown out each year — more than double what we tossed two decades ago. Americans consume more than 20 billion garments each year, and each garment can be expected to be worn around seven times, according to The Wall Street Journal. We’re buying more clothing than ever when clothing is at its lowest cost. Read more.

New surfing lagoon paradise to bring ocean-perfect waves to Houston

Surf's up soon for Houstonians thanks to this new innovative development. Rendering courtesy of Beach Street Development

Thanks to its relative proximity to the coast, Houston has always enjoyed an underground surf culture (be it shortboarding, longboarding, or even tanker surfing). Now, those who walk the nose and shred can at a new, world-class surf destination coming to Generation Park in north Houston.

HTX Surf will ride into Generation Park in fall of 2024, per an announcement by creators Beach Street Development, the company pushes the barefoot life with its man-made surfing lagoons.

Why the north Houston locale, versus closer to Galveston? Beach Street notes in press materials that the lagoon park is a mere 10 minutes from Bush Intercontinental Airport, making for easy access for visitors from all over. Read more.

Laundry startup unfolds new service in Houston

Hampr Lite will give Houstonians a taste of what it's laundry service is like. Image courtesy of Hampr

As Laurel Hess sat on a video call with a board member for her startup laundry service, a pile of laundry was peeking behind her.

“How can you have clothes piling up while owning a laundry business?” they asked.

Hess coolly replied, “Because laundry just doesn’t stop. It’s literally always there.”

Hampr is a hyper-local laundry and pick-up service that is connected and operated through an online app. The Lafayette-based company, which identified Houston as an early test market, links people who are in need of pick-up and wash laundry services with people in the local communities who are seeking work without leaving home. Read more.

Houston restaurant veteran pops open award-winning and sustainable new bottled water

HOW water comes to you via subscription. Photo by Alex Montoya

Houstonians who are picky about their bottled water but also environmentally minded now have a refreshing local option — one that even comes to them.

A new, “hyperpure” oxygen-enriched water brand has rolled out in Houston in single-serve and subscription options. Dubbed HOW — Hyperpure Oxygenated Water — the award-winning super-filtered water (via a 14-level filtration process that removes impurities down to the nano-level .0001 microns) is now available at 35 specialty retailers around town. Read more.

Celebrity family inks exclusive deal with Houston-based real estate platform ahead of return to HBO

The Hos are back for Season 2 after inking a big deal with Realty.com. Photo by Elizabeth Morris/HBO Max

Houston power fam The Hos are once again back in the house. The docu-reality series stars of House of Ho returned to streaming network HBO Max for a 10-episode second season this week.

Season 2 kicks off with three episodes, with three new episodes to follow on September 1, and the final four episodes debuting September 8, according to HBO.

As fans recall, Season 1 introduced the nation to patriarch Binh and matriarch Hue, who went from Vietnamese immigrants to building a multi-million dollar real estate and banking empire. The Season 1 cast included the Hos’ son Washington and his wife Lesley; their daughter Judy and her fiancé Nate Nguyễn; and Aunt Tina; and Cousin Sammy, who has become an influencer with a propensity for ending posts with “b*tches.”

Aside from flashing their opulent lifestyle and navigating cultural clashes, the Hos are still wheeling and dealing. The Houstonians have inked an exclusive deal with Realty.com to “deliver world-class service to clients in the Houston area,” according to a Realty.com announcement. Read more.

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Greentown Labs names Lawson Gow as its new Houston leader

head of hou

Greentown Labs has named Lawson Gow as its Head of Houston.

Gow is the founder of The Cannon, a coworking space with seven locations in the Houston area, with additional partner spaces. He also recently served as managing partner at Houston-based investment and advisory firm Helium Capital. Gow is the son of David Gow, founder of Energy Capital's parent company, Gow Media.

According to Greentown, Gow will "enhance the founder experience, cultivate strategic partnerships, and accelerate climatetech solutions" in his new role.

“I couldn’t be more excited to join Greentown at this critical moment for the energy transition,” Gow said in a news release. “Greentown has a fantastic track record of supporting entrepreneurs in Houston, Boston, and beyond, and I am eager to keep advancing our mission in the energy transition capital of the world.”

Gow has also held analyst, strategy and advising roles since graduating from Rice University.

“We are thrilled to welcome Lawson to our leadership team,” Georgina Campbell Flatter, CEO of Greentown Labs, added in the release. “Lawson has spent his career building community and championing entrepreneurs, and we look forward to him deepening Greentown’s support of climate and energy startups as our Head of Houston.”

Gow is the latest addition to a series of new hires at Greentown Labs following a leadership shakeup.

Flatter was named as the organization's new CEO in February, replacing Kevin Dutt, Greentown’s interim CEO, who replaced Kevin Knobloch after he announced that he would step down in July 2024 after less than a year in the role.

Greentown also named Naheed Malik its new CFO in January.

Timmeko Moore Love was named the first Houston general manager and senior vice president of Greentown Labs. According to LinkedIn, she left the role in January.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.