This week's roundup of Houston innovators includes Sarah "Sassie" Duggleby of Venus Aerospace, Youngro Lee of Brassica, and Le Dam of myAvos. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from rocket science to fintech — recently making headlines in Houston innovation.

Sarah "Sassie" Duggleby, CEO and co-founder of Venus Aerospace

Sarah "Sassie" Duggleby of Venus Aerospace joins the Houston Innovators Podcast this week. Photo courtesy of Venus

Sarah "Sassie" Duggleby and her husband were living in Japan and considering a trip back to Texas and wishing there was a faster option than a full day of international travel — with their kids, no less. That's when Andrew Duggleby told Sassie that there actually might be an engine that could do that.

Flash forward a few years, and the husband-wife team has built a company around that idea. Venus Aerospace, originally founded in California, relocated to Houston in 2021 to establish their company in an ecosystem with the tools to advance their tech — and give their employees a good work-life balance, Sassie Duggleby explains on the Houston Innovators Podcast.

"We knew we had to find a location where we could test our engine and still be home for dinner," she says on the show. "Our company vision is 'home for dinner.' We want to fly you across the globe and have you home for dinner. And, if you work for us, we want you home for dinner." Read more.

Youngro Lee has announced funding for his latest fintech endeavor. Photo courtesy

Youngro Lee is no stranger to shaking up the finance world with a new tech-based way of doing business. One of the founders of NextSeed, Lee's newest mission is providing "investment infrastructure as a service" with his company, Brassica, which just raised $8 million in seed funding.

“The future of finance will depend on the ability of trustworthy institutions to provide secure and seamless transitions between traditional financial services and web3 innovations while complying with strict regulations and still providing great customer experience,” says Lee in the news release.

Houston-based Mercury Fund led the round with several other investors participating. Read more.

Le Dam, CEO and founder of OptiChroniX

Le Dam moved from California to Houston to build her company. Photo via LinkedIn

After years on the West Coast, Le Dam has returned to her adopted hometown of Houston — just in time to launch a new app dedicated to providing health resources and information to its users.

“I always knew that I wanted to build my business in Houston,” Dam says, mentioning the assets of the world’s largest medical center, a thriving startup community, and diverse population for whom she wants to build her technology.

myAvos pairs with a user’s smart watch and harnesses their health information such as physical activity and hours slept. The user can also input additional information such as blood test results and meals eaten. The app analyzes the information provided and assesses the user’s risk for chronic illness later in life. Read more.

This week's roundup of Houston innovators includes Alessio Lorusso of Roboze, Tobi Smith of All I Do Is Cook, and Pradeep Sharma of the University of Houston. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from 3D printing to food and cooking — recently making headlines in Houston innovation.

Alessio Lorusso, founder and CEO of Roboze

Alessio Lorusso joins the Houston Innovators Podcast to discuss why he chose Houston to set up U.S. operations for his large-scale 3D printing company, and how the city has the potential to become a hub for the industry. Photo via LinkedIn

The hit the pandemic has had on the global supply chain has been a huge hit to so many companies. However, one Italian company with its United States headquarters in Houston, has an alternative for customers — large scale, in-house production. Roboze, which recently completed a multimillion-dollar fundraise, has seen explosive growth due in large part to how COVID-19 has affected the global supply chain over this past two years.

"This was an incredible accelerator for us," says Alessio Lorusso, CEO and founder, on the Houston Innovators Podcast. He adds that, while Roboze has attracted large corporate customers, the business is seeing growth in the small to mid-sized company sector.

"The moment is now," Lorusso says. "The time to integrate printing capabilities and have the possibility to print parts in house is something that needs to be done now." Click here to read more and listen to the podcast.

Tobi Smith, founder of All I Do Is Cook

All I Do Is Cook is on a mission to grow accessibility to Nigerian dishes. Image via allidoiscook.com

Tobi Smith wanted to take his business to the next level — and he found the perfect opportunity to do so. After completing the gBETA accelerator program and winning the grand prize in the ClearCo ClearPitch competition, Smith and his business partner Bethany Oyefeso are transitioning their small business, All I Do Is Cook, into a startup with the ultimate goal of making Nigerian food accessible to everybody.

Smith and Oyefeso came one step closer to that goal when Phoencia, a Houston grocery story, started stocking the startup's condiments in 2021. In that same year, Smith and Oyefesso joined the gBETA accelerator program. Smith described this program as being instrumental in the advancement of their company from a small business to a start up, now at the beginning of their pre-seed funding phase.

“They taught us everything about what it meant to be a start up and connected us with mentors and other individuals working in the food and beverage space,” says Smith. Click here to read more.

Pradeep Sharma, engineering department chair at the University of Houston

Pradeep Sharma, M.D. Anderson Chair Professor and department chair at the University of Houston, was named to the National Academy of Engineering. Photo via uh.edu

The National Academy of Engineering elected its new members, and five local scientists are among the new 133-person cohort — as is Elon Musk, if you were wondering. The appointment is among the highest professional distinctions in an engineer's career.

Pradeep Sharma, M.D. Anderson Chair Professor and department chair, Department of Mechanical Engineering, University of Houston, was recognized for establishing the field of flexoelectricity, leading to the creation of novel materials and devices and insights in biophysical phenomena.

“Nature has provided us very few piezoelectric materials even though their applications in energy harvesting and in making sensors is very important. What we did was use theory to design materials that perform like piezoelectric ones, so that they can create electricity,” says Sharma in the release. Click here to read more.

This week's Houston innovators to know include Megan Eddings and Amanda Cotler of Accel Lifestyle and Brad Burke of Rice Alliance. Photos courtesy

3 Houston innovators to know this week

Who's who

It seems like 2020 is the year of the pivot and taking what the world has thrown at you —from pandemics to oil gluts — and making something out of what you have.

This week's innovators to know include a Houston startup flipping the switch on production to make face masks to the Rice Alliance re-envisioning an annual event that usually takes place at a global conference.

Megan Eddings and Amanda Cotler of Accel Lifestyle

Photos courtesy

When Megan Eddings and Amanda Cotler saw the CDC was recommending medical professionals wear bandanas or strips of cloth when surgical face masks weren't available, they had an idea.

The duo behind Accel Lifestyle, a Houston-based athletic wear startup that has a bacteria-resistent fabric, hopped on a call to see how they could rework their supply chain to quickly pivot to making face masks.

When setting up the company, Eddings, Accel's founder, made it a priority to avoid sweatshops, and she set up her supply chain to be completely within the United States — something that's been beneficial to the company's COVID pivot.

"If we did not have a 100 percent domestic supply chain, there's no way we could have done this," Eddings says.

Eddings and Cotler joined the Houston Innovators Podcast to share the story of how Accel went from deciding to make the masks to selling them by the thousands to Houston Methodist.

"When you think of face masks, you wouldn't think about activewear or thinking of Accel being a part of the fight against coronavirus," Cotler says. However, that might no longer be the case for the company now. Click here to learn more and to stream the podcast episode.

Brad Burke, managing director of the Rice Alliance for Technology and Entrepreneurship

Photo via alliance.rice.edu

Rice Alliance for Technology and Entrepreneurship typically hosts their Energy Tech Venture Day from the one of the halls within NRG Arena at the annual Offshore Technology Conference. However, the conference that attracts thousands of people from around the world, much like so many events, was canceled due to coronavirus.

But Brad Burke and his team at the Rice Alliance turned to tech to introduce the first virtual event, which then took place on Thursday, May 7. Burke introduced the event that had 39 startups that represented 11 different states and six different countries, 13 call Houston their HQ.

"We had many startups and corporations reach out to us and ask us if we could go ahead with the event in a virtual format, so that's how we ended up where we are today," says Burke. Click here to read more.

This week's innovators to know are Debbie Mercer, Andrew Bruce, and Maria Maso. Courtesy photos

3 Houston innovators to know this week

who's who

While headlines about coronavirus keep multiplying — similar to the virus' cases, Houston's innovation news hasn't yet slowed.

This week's people to know include a female entrepreneur who's leveling the playing field for outdoorsy women, a blockchain expert with new growth, and an investor creating the angel network she's been wanting for years.

Debbie Mercer, founder of Zip Hers

Photo courtesy of Zip Hers

Debbie Mercer, a Houston entrepreneur, has designed articles of clothing to empower female athletes. The marathon runner was tired of seeing female runners standing in long lines, awaiting their turns to do their business behind closed doors, while their male friends resorted to quickly and discreetly ducking behind the porta-potties, or finding nearby trees. Precious time ticked by as the women watched their male counterparts continue the race.

The Houstonian created Zip Hers, an activewear brand that has a full-length zipper lining the bikini area of each pant, to accommodate on-the-go women. The Zip Hers concept and design was intended to level the playing field for women and men when it comes to competitive sports.

"If we're wasting time on a bathroom break and they're not, that holds us back…Maybe it's our little tiny contribution to women's equality. We just really want to help women be the best that they can be," Mercer says. Click here to read more.

Andrew Bruce, CEO and founder of Data Gumbo Corp.

Photo courtesy of Data Gumbo

For the fist time, Data Gumbo Corp.'s GumboNet will be used in geothermal energy drilling thanks to the startup's new Indonesia-based client, Air Drilling Associates, a drilling and project management service provider.

"Expansion into Southeast Asia with ADA's deployment signals GumboNet's global applicability and benefit to industry — in this case, geothermal energy development," says Andrew Bruce, CEO and founder of Data Gumbo, in a news release. "We are excited that Data Gumbo is entering yet another sector of the energy market for improvements across its supply chain." Click here to read more.

Maria Maso, founder of Business Angel Minority Association

Photo courtesy of Nijalon Dunn

Maria Maso, frustrated with her investment opportunities in Houston, has launched the Business Angel Minority Association, or baMa, to gather established or brand new angel investors to move the needle on investments into minority-founded startups. Maso, founder and CEO, and Garaizar, president, want to round up 100 investors by the end of 2020. And they want these investors to write checks.

"We are not a networking organization. We are an investment organization. We are expecting at some point that you are writing a check to a startup," Maso says. "If we are doing our job properly and we are showing you the right startups, you should be able to make a check at some point." Click here to read more.

This week's innovators to know are focused on bringing startup programming and venture capital to Houston. Courtesy photos

3 Houston innovators to know this week

who's who

This past week has been full of exciting innovation news in Houston — from big fundraising round closings to a new unicorn coming out of the Bayou City.

Houston innovators to know this week include a new program director for Houston's newest startup accelerator, a venture capital fund leader, and more.

Eléonore Cluzel, program director of gBETA Houston program as director

Courtesy of gBETA Houston

Houston's newest accelerator program, gBETA, named its new local leader. Eléonore Cluzel will lead the gBETA Houston program as director, and will be the point person for the program in the region for the two annual cohorts. Previously, Cluzel worked for Business France mentoring French startups and small businesses. In her new position, she says she's excited to support founders across all industries and foster innovation.

"We're adding another resource for local founders to grow their startups and to raise money, and not have to move to Silicon Valley to do it," she says. "We will also serve as a connector, introducing founders to mentors and investors within the community and across gener8tor broader network." Click here to read more.

Sandy Wallis, managing director of the HX Venture Fund

Courtesy of Sandy Wallis

After 20 years in the venture capital world, Sandy Guitar Wallis has seen the evolution of investing — on both coasts and here in Houston as well. Now, as managing director of the HX Venture Fund, Wallis leads the fund of funds that's investing in VCs around the country in order to bring investment to Houston.

"We have raised a fund of funds with the HX Venture Fund, and we're deploying that capital across probably 10 venture capital funds over time," Wallis explains on the most recent episode of the Houston Innovators Podcast. "Each one of those funds, will invest in 15 to 20 underlying private companies. So, at the end of the day, HX Venture Fund 1 will have exposure to 10 VC funds, as an example, and — by virtue of those investments — maybe 300 private companies." Click here to read more.

James Y. Lancaster, Texas branch manager for Arkansas-based VIC Technology Venture Development

Photo courtesy of VIC

Startups fail — and there are a number of reasons why that is. James Y. Lancaster, who serves as Texas branch manager for Arkansas-based VIC Technology Venture Development, writes in a guest column for InnovationMap about the second most common reason for startup failure: funding.

"A key part of the startup CEO's job is to understand how much total cash remains on hand and whether it is enough to carry the startup towards a milestone that can lead to successful financing as well as a positive cash flow," Lancaster writes. "Just as important is how to allocate their time and efforts to the fundraising process along the way." Click here to read more.

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7+ can't-miss Houston business and innovation events in June 2026

where to be

Editor's note: The FIFA World Cup comes to Houston this month, joined by major energy conferences and a lineup of fan-favorite, recurring events. Here’s what not to miss and how to register. Please note: this article may be updated to add more events.


June 1-4 — CLEANPOWER 2026 Conference and Exhibition

CLEANPOWER unites policymakers, experts, and corporate leaders to solve the challenges that none can solve alone. This must-attend, four-day conference is packed with cutting-edge discussions about wind, solar, storage, and transmission; dealmaking; networking; and fun.

This event begins June 1 at the George R. Brown Convention Center. Register here.

June 2 — Humans of Healthcare

Houston Methodist Center for Innovation will present its quarterly speaker series, Humans of Healthcare. The series will feature a panel of experts who will share about their career paths and discuss the nuances of the health care industry. This month's session will focus on today’s nursing landscape, the industry’s expectations of nurses and what career paths are possible in the field.

The event is Tuesday, June 2, from 5-6:30 p.m. at the Ion. Register here.

June 9 — Greentown Go Make Kickoff

Head to the Ion to celebrate the Greentown Go Make 2026 cohort. The open-innovation program with Shell Catalysts & Technologies and Technip Energies focuses on catalytic solutions for industrial decarbonization and the energy transition. Hear pitches from the founders and network with a select group of startups while enjoying food and drink.

This event is Tuesday, June 9, from 5:30-8 p.m. Register here.

June 9-10 — Texas Brain Economy Summit

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. Expect to hear from leaders of global institutions, including the World Economic Forum, U.S. Chamber of Commerce, McKinsey Health Institute, Global Brain Economy Initiative, Davos Alzheimer’s Collaborative, Business Collaborative for Brain Health (UsAgainstAlzheimer’s), Rice University, Memorial Hermann, MD Anderson and many others. Read InnovationMap's full preview of the event here.

This event begins Tuesday, June 9. Purchase tickets here.

June 10 — MIT Future of Healthcare Technology Forum

The MIT Club of South Texas will host an in-person forum to explore how innovation, government and policy are changing the healthcare industry. The event will feature MIT alumni and Houston healthcare leaders, including Dr. Tim Boone, dean of the Texas A&M School of Engineering Medicine; Cynthia Reinhart-King, chair of bioengineering at Rice University; Dr. Tony Lin, CEO and chairman emeritus of Kelsey-Seybold Clinic; and others.

This event is Wednesday, June 10, from 5:15-8:30 p.m. at the TAMU EnMed Building. Register here.

June 11 — Goals & Gigawatts: Houston Energy & Climate Week The Power of & Kickoff Party

Come watch the Mexico City FIFA opening match while celebrating energy and innovation at the Goals & Gigawatts Kickoff Party. The event will feature food, drinks, and a showcase on Houston Energy & Climate Week. Learn what to expect and how to get involved in HECW before closing the night with a DJ and karaoke.

This event is Thursday, June 11, from 1:30-6:30 p.m. Find more information here.

June 16-17 — Energy Projects Conference & Expo

The Energy Projects Conference & Expo (EPC Show) is the largest event in North America for professionals working at the heart of major energy projects. The essential event for engineering, construction, commissioning, operations and maintenance across multiple energy sectors brings together five leading conferences under one roof. Conference subjects span LNG exporting, hydrogen and ammonia, midstream, petrochem and refining, and sustainable aviation fuels.

This event begins June 16 at George R. Brown Convention Center. Register here.

June 25 – NASA Tech Talk

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing, and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, June 25, from 6-7 p.m. at the Ion. Register here.

Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”