Allie Danziger joins the Houston Innovators Podcast to discuss her edtech startup Ampersand's exit. Photo courtesy of Ampersand

For the second time in less than six years, Houston entrepreneur Allie Danziger has navigated a company through an exit. But, with the two exists under her belt, Danziger says the two transactions could not be any more different.

Danziger founded Integrate Agency, a digital-focused public relations firm, in 2009 and sold it to another marketing and PR firm based in Austin in 2018. She founded her next company, Ampersand Professionals, in 2020 to address the challenges for upskilling young professionals to prepare them for success in the workplace — something employers really wanted, but struggled to do consistently.

Last month, Ampersand was acquired by Ascent Funding, a college loan provider that's building out a platform to support its college-aged borrowers. In this week's episode of the Houston Innovators Podcast, Danziger shares how this opportunity came about and looks back on these two pivotal deals.

"Integrate definitely was not built to sell — I didn't even know that people sold businesses when I was 24 (and started the agency," Danziger, who worked in PR her entire career at that time, says, adding that she thought she'd work at the company her whole life before passing it down to her children. "It ended up being a life-changing experience and opportunity because it did open my eyes up to other other things that I could do professionally — and also just kind of like the way that businesses are structured and run."

One of those things she considered post acquisition was upskilling entry-level employees. At Integrate, she hired a lot of interns and recent college graduates. She recognized there was a gap in the market. The first problem she identified was the need to match interns to positions at companies in an optimized way. While that's how the company started, it pivoted as Danziger says she saw the bigger need not for finding interns, but for making sure they were ready for their positions from the start.

"Most business leaders need their interns and entry-level employees starting day one with an understanding of how to communicate, and they don't really have the resources to teach them some of these skills," she explains.

Once the Ampersand platform, which has tons of resources and hours of instruction loaded on it, the challenge was finding the stakeholders that wanted the platform to exist — her potential customers. Was it the colleges or the employers? Through this journey, she realized that college loan lenders are part of that equation too.

"The lenders — the ones who are giving the student loans — they're the ones who really need them to be successful in the workplace," Danziger explains, saying the success of their loan recipients ensures a timely payout for the lender. "Their business model is predicated on students being successful, and I'd always known that, but not quite known what to do with that knowledge."

Danziger says the idea for acquisition, while always in the back of her mind, really became a possibility when she went out to raise funding.

"You're always raising money, and you're always for sale," Danziger says of the startup journey.

When a potential investor raised the idea of being a potential acquirer, Danziger says she started doing some soul searching. The right acquisition deal could help her address the milestones she wanted to reach with investment funding — growing her team, expanding her technology, and broadening reach. Through a diligent process, Danziger decided on Ascent from a few other potential acquirers.

"I'm not going anywhere. I want to still keep solving this problem, but with a larger team and larger resources," she says. "Either I could go find that myself, or I could join forces we could join forces with an established organization."

Danziger says her role at Ascent is still being constructed in terms of scope and responsibilities, but her title as of now is senior vice president and general manager of student success. She will lead the company's educational program that focuses on equipping students with skills from education to employment.

She shares more on the acquisition process — including her advice to startups thinking about the M&A path. Listen to the interview here — or wherever you stream your podcasts — and subscribe for weekly episodes.

This week's innovators to know are Allie Danziger, Sylvia Kampshoff, and Brittany Barreto. Courtesy photos

3 female Houston innovators to know this week

Who's who

This one's for the ladies. InnovationMap's weekly roundup of innovators to know features three female founders — one is offering her advice on crisis communications, one is innovating the at-home workout, and one is planning on making Houston a city for femtech.

Allie Danziger, founder and president of Integrate Agency

Photo courtesy of Integrate

Now more than ever your company's message is extremely important, says communications expert Allie Danziger, and she and her company, Integrate Agency are focused on helping businesses at this trying time.

"Practicing what we preach, we understand that as communication experts, it is our mission and responsibility during this time to help our local business community," writes Danziger in her guest column. "We are putting our money where our mouth is and for the last week have been offering free communication and marketing consultation to any business in need."

Click here to read the rest of Danziger's column.

Sylvia Kampshoff, founder of Kanthaka

Photo courtesy of Kanthaka

Big-box gyms have the potential of being a breeding ground for the coronavirus, but smaller studios aren't immune from the disease's consequences either. While most fitness spots have closed to prevent the spread of COVID-19, Houston-based Kanthaka has been using tech to enable at-home exercise before it was the only option.

That's why the app's founder Sylvia Kampshoff says she saw a huge spike in numbers last week as things began to close. Kanthaka allows users to book personal training sessions to their home. The one-on-one interaction has become really popular in this time of social distancing, and Kampshoff say soon the app will go even further in their efforts allowing its personal trainers to give virtual one-on-one training.

Click here to read more about Kanthaka's latest initiatives.

Brittany Barreto, venture associate at Capital Factory

Photo courtesy of Brittany Barreto

Brittany Barreto is passionate about femtech, helping entrepreneurs, and, despite being from the Northeast, Houston. Barreto joined the Houston Innovators Podcast this week to discuss her passions and her use to the Houston innovation ecosystem as a former founder herself.

"I actually think Houston needs to figure out how to capitalize on these recycled founders and how to get them in more mentorship and leadership positions," Barreto says on the podcast. "We're in Houston, Texas, and the second question out of everyone's mouths is, 'How can I help you?'"

Click here to stream the episode and read more about Barreto.

When faced with a crisis, it's essential to deliver clear, authentic messages to your target audiences. Getty Images

Houston entrepreneur shares communication tips for today's coronavirus environment

Guest column

The reality for business owners is that everything you say matters; your words are reverberated and felt throughout the company and all of your stakeholders.

During times of crisis, your voice is amplified to the max, and people listen to every word you have to say, which is why — if not completely thought-through — your voice can breed misinformation, confusion and stress. As we face the increasing uncertainty in our community due to the spread of COVID-19, it's critical for business owners to say the right things, to the right people, that will inform and motivate, and use their presence and organization to be leaders within the community.

Practicing what we preach, we understand that as communication experts, it is our mission and responsibility during this time to help our local business community. We are putting our money where our mouth is and for the last week have been offering free communication and marketing consultation to any business in need.

So, what is top of mind to our team right now, as we work with these businesses? Besides following recommendations from the U.S. Center for Disease Control and Prevention to curb the virus's spread, companies should actively be communicating to all stakeholders about the impact COVID-19 is having or could have on operations. Here are a few dos and don'ts to get you started.

Offer valuable tips to prevent the spread of respiratory diseases, but we all know to wash our hands by now.

You have to make sure that you are communicating valuable information with internal and external stakeholders — but through your own authentic voice. Offer suggestions on how to "social distance" or use your service/product remotely.

Internal stakeholders need to understand what's hard facts, what's soft facts (opinions and feelings) and what's just hearsay. They need to understand clear expectations when working from home and employees need to feel safe, accommodated and heard. Externally, be sensitive to what your customers and the community at large are going through and update your business practices and communications accordingly.

Communication with customers can be in an email, but you can also connect through text, through an online chat, via infographics or memes on social media, or an "on-brand" (and possibly witty!) reminder on what social distance may mean.

Don't stay silent — even if you don't know everything.

Don't let others control your company's narrative. As humans, we naturally fill in gaps in communication to understand what's going on around us. Rather than letting people assume information about your business, get in front of the conversation and share real-time updates as you adjust business-as-usual.

Consider alternative ways to reach external audiences and vice versa.

What happens if the majority of your customer acquisition model is door-to-door and no one wants to open the door to a stranger, or you have a centralized call center to handle customer service complaints, but these employees are now all working from home? Now is the time to reconsider how you'll engage with your audiences and win customers.

We recommend a significant shift to digital acquisition as people are going to be spending more and more time online in the coming weeks from home and there is a ripe opportunity to stay top of mind through targeted display campaigns and send interested customers to your website.

Create a proactive plan for shut downs.

Coronavirus is still an emerging, rapidly evolving situation and we have no idea what could happen but create contingency plans and have a crisis comms plan ready to deploy. Think through possible scenarios (closures, supply limitations, employee diagnosis, etc.) and have social media posts, email blasts and internal messaging ready to deploy should worst case scenario occur.

What your business says is just as important as who says it.

A spokesperson is your organization's mouthpiece. Choosing the right person is just as important as saying the right thing. Without the right person to speak on behalf of your organization, your message could be lost — or worse, they choke.

Your spokesperson should be credible, empathetic and authoritative.


Bottom line: When faced with a crisis, it's essential to deliver clear, authentic messages to your target audiences, stay true to your brand voice and position yourself as a leader – both internally and externally. Your company will thank you later.

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Allie Danziger is the founder and president of Houston-based Integrate Agency, which focuses on digital marketing and public relations.

From rethinking dry cleaning or marketing to flipping the script on pop culture events, here's who to know this week in Houston innovation. Courtesy Photos

3 Houston innovators to know this week

Who's Who

This week's batch of Houston innovators to know are all rethinking the way things are being done, from dry cleaning and marketing to pop culture events. Scroll through to see who's who in Houston innovation this week.

Safir Ali, founder and CEO of Hamper

Safir Ali leads Houston-based Hamper, which won the Rockets and BBVA Compass' LaunchPad competition. Courtesy of Hamper

It's a good week for Safir Ali, who's company just won a startup competition put on by the Houston Rockets and BBVA Compass. Hamper, his company, makes dry cleaning more convenient for customers with pick up and delivery. His parents run a dry cleaning shop and he always thought it was a bit antiquated.

"I had this 'aha' moment in 2016," Safir says. "I had graduated from Texas A&M in 2014 and was working a corporate job and the last thing on my mind was joining the family business. But I started to see all the pain points for people in dry cleaning." Learn more about Hamper here.

Allie Danziger, founder and president of Integrate Agency

When it comes to setting up a marketing budget for your startup, considering every angle is important, says Allie Danziger of Integrate Agency. Getty Images

Allie Danziger has been focused on digital marketing since before it was cool. The entrepreneur created her Houston agency 10 years ago and has been growing ever since. She wrote a guest column for InnovationMap last week about how startups and small businesses should decide on how much to spend on marketing.

"Industry research suggests spending 5 percent to 12 percent of total revenue on an annual marketing budget," she writes. "At Integrate Agency, we believe marketing spend should be determined from key data points, versus current size." Click here to read the rest of the article.

Michael Heckman, Comicpalooza president and senior vice president at Houston First

Michael Heckman shares about some exciting new aspects of Houston's 11th annual Comicpalooza. Courtesy of Houston First

It's safe to say that Michael Heckman has had a busy weekend. The 11th annual Comicpalooza took over downtown Houston this past weekend, but just because one event is over, doesn't mean Heckman or his team at Houston First Corp. is slowing down.

"Our convention sales team looks to break another record this year," Heckman tells InnovationMap. "We have a lot of major events upcoming — from the college football playoff to the men's basketball Final Four, and we'll eventually pursue another Super Bowl."

Heckman says he has some big ideas for even an innovation-focused conference. Read the rest of the Q&A with Heckman here.

From the real estate needs of the innovation ecosystem to the most promising OTC startups, here are this week's trending stories. Shobeir Ansari/Getty Images

5 most popular innovation stories in Houston this week

What's trending

The annual Offshore Technology Conference has wrapped up, but not before the Rice Alliance named 10 promising startups — most of which have headquarters or operations in Houston. Now, Comicpalooza is taking over for what is expected to be a record year. These stories and more all trended on InnovationMap — here's what else trended.

Need more than just trending news on Fridays? Subscribe to our daily newsletter that sends fresh stories straight to your inboxes every morning.

Rice Alliance names the 10 most promising startups at Houston's Offshore Technology Conference

Startups from across the world pitched at the Rice Alliance Startup Roundup at the Offshore Technology Conference. Getty Images

Over 50 different startups from across the globe gathered at the Offshore Technology Conference for the fifth annual Rice Alliance Startup Roundup event. The full day of speed pitching and presentations, hosted by Rice Alliance Managing Director Brad Burke, took place at NRG Arena on Monday, May 6.

After interacting with all the various startups, the Rice Alliance's panel of experts voted on the 10 most promising startups. Half of the companies that were recognized are based in Houston — and even more have an office or some sort of operations in town. Here's which technologies the offshore oil and gas industry has its eye on. Read the full story here.

Comicpalooza expects another record year, says Houston First Corp. executive

Michael Heckman shares about some exciting new aspects of Houston's 11th annual Comicpalooza. Courtesy of Houston First

Eleven years ago, Comicpalooza was a small event held out in Katy. Over the past few years, with the help of Houston First Corp., the three-day conference has grown to be so big, the 2019 programming will spill out of George R. Brown Convention Center and into Discovery Green, and attract over 50,000 attendees.

"These comic conventions used to just be for the hardcore pop culture fans. What we've attempted to do is make it so there's something for everyone," says Michael Heckman, Comicpalooza president and senior vice president at Houston First. "As a casual pop culture fan, there's a lot to see and do." Read the full story here.

Data Gumbo closes $6M round, Alice partners with accelerator, and more Houston innovation news

Blockchain-as-a-service company closes $6 million Series A round. Courtesy of Data Gumbo

Houston's innovation ecosystem has been busy, and the ongoing 50th anniversary of the Offshore Technology Conference has claimed a lot of attention in town lately. While I'm sure you've seen the big news pieces, like the Texas Medical Center's new details about TMC3 or WeWork's third Houston location, you may have missed some of these short stories. Read the full story here.

Houston expert shares her advice on how much startups should spend on marketing

When it comes to setting up a marketing budget for your startup, considering every angle is important. Getty Images

Industry research suggests spending 5 percent to 12 percent of total revenue on an annual marketing budget. At Integrate Agency, we believe marketing spend should be determined from key data points, versus current size. We shepherd our clients through a five-step process to calculate how much they should spend on marketing to maximize their ROI. Read the full story here.

Overheard: Panel of experts sums up the Houston innovation ecosystem's real estate needs

Houston's innovation ecosystem development is highly interconnected to the city's real estate industry. Shobeir Ansari/Getty Images

As the city and multiple entities strive to develop an innovation hub and ecosystem, real estate plays a huge role. Developing the physical space is one of the first steps to attracting companies, talent, and money to the Bayou City.

At Bisnow's annual Houston State of the Market event, five panelists heavily involved in the process of developing Houston's innovation ecosystem weighed in on the real estate needs of innovation development in Houston. Check out these powerful quotes said during the panel. Read the full story here.

When it comes to setting up a marketing budget for your startup, considering every angle is important. Getty Images

Houston expert shares her advice on how much startups should spend on marketing

Is the price right?

Industry research suggests spending 5 percent to 12 percent of total revenue on an annual marketing budget. At Integrate Agency, we believe marketing spend should be determined from key data points, versus current size. We shepherd our clients through a five-step process to calculate how much they should spend on marketing to maximize their ROI.

1. Know your goals

You can't manage what you can't measure. Before you start spending, you must first set SMART goals. Challenging, but realistic, short-term goals may include:

  • Sales/revenue growth
  • Customer count
  • Consumer ratings improvement

Integrate updated Delmar Systems' website with the goal of increasing traffic that would generate leads. By having a clear goal at the forefront, Integrate created a conversion-focused website and calculated an ROI for the company (including 631.9 percent increase in new visitors and 23.9 percent increase in qualified leads).

Your goals should set a strong baseline of expectations and establish clear guidelines for the budgeting strategies to reach those goals.

2. Know your data

You can only track your goals, and tweak your spend accordingly, if you have the specific data to tell you what's working and what isn't. Some of our favorite tools include:

  • Google Analytics for visitors, bounce rate, and time on site
  • Site Checker for SEO performance
  • Conductor for content efficacy
  • Sprout Social for social media metrics

One of our clients wanted to increase its qualified leads, but before we added more dollars to the equation, a full audit of the company's digital efforts uncovered significant spend inefficiencies. The data uncovered a new strategy that led to a full revamp of its PPC campaign. This helped them save $8,000 per month and led to a 63.9 percent year-over-year decrease in cost-per-click cost and 42.3 percent year-over-year increase in click through rate.

3. Know your audience

If you have a strong concept of your customer base, you'll know where, when, and how you can best connect with them.

To this end, we are hyper-aware of our clients' seasonality and when their audience is most likely to buy (and for B2B clients, when budget review season is) so we can target their marketing budget accordingly.

Six Flags Hurricane Harbor Splashtown operates on a seasonal basis, by its very nature. Each summer, Integrate focuses on a concentrated marketing approach and last year garnered over 540 million traditional media impressions in just four months.

This activity has ensured they're top-of-mind when it matters most, versus spending dollars when their customers are not considering this purchase.

4. Know your competition

Regardless of market share, it's important to keep up with what competitors are doing. We recommend beginning your competitor research with:

  • SEM Rush for SEO keyword research
  • Majestic SEO for linking statistics
  • Ahrefs for backlink strategy
  • Moz for rank tracking

When Escalante's sought to outmaneuver its competition with digital tactics, Integrate's competitive data revealed that none of its competitors in a specific neighborhood were being overly aggressive online.

By focusing on geo-targeting and ad scheduling to ensure ads displayed to the preferred audience at the right time, the restaurant has been able to capitalize on specific traffic without a large budget.

5. Know your capabilities

A question will often come up about in-house vs. outsourced marketing. In-house gives you maximum control. But, to be most effective with your spend (and often attune to the latest, best-in-class, industry techniques), you must fully commit to your marketing efforts, which an agency, or outside partner, can provide.

As one client — Arthritis Relief Centers — grew, their staff no longer had the time to devote to marketing. By making the decision to work with Integrate, the company had more time to devote to patient care. This led to an over 100 percent increase in clicks to digital ads and a 56 percent decrease in cost-per-click because the client trusted the agency's digital marketing expertise.

The biggest upside to outsourcing your marketing: letting your team focus on servicing customers and improving your products.

As we stated earlier, the experts tell you that your marketing spend should normally live between 5 and 12 percent of your gross revenue, but we believe your marketing budget, and the integrated mix of how that budget is implemented, should be tied to growth needs and goals.

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Allie Danziger is the founder and president of Houston-based Integrate Agency, which focuses on digital marketing and public relations.

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Houston e-commerce giant Cart.com launches government-focused subsidiary

government branch

Houston e-commerce and logistics unicorn Cart.com has launched a new subsidiary.

Cart Government Solutions (CGS), which was announced earlier this week, will provide supply chain and logistics services and software for the federal and state government sectors. The new subsidiary will be headquartered in Washington, D.C., and operate out of about 6 million square feet of secure warehouse space across 14 U.S. facilities, according to a news release from Cart.com. It will support both domestic and overseas logistics.

Industry veteran Gregg Zegras will lead the new entity as president. Zegras previously served as Cart.com's chief revenue officer, according to LinkedIn. Before that, he served as president of Connecticut-based Pitney Bowes Global eCommerce, a digital shipping solutions company.

Remington Tonar, Cart.com's co-founder, will serve as CGS's chief innovation officer.

“Government agencies face procurement and logistics challenges that many commercial platforms simply weren’t built to solve,” Zegras said in the news release. “Cart Government Solutions exists to change that. We’re combining the speed and innovation of a technology company with the compliance rigor, security, and operational depth that federal and state customers require, and we’re doing it with a team that has spent careers working alongside and inside these agencies.”

According to the company, CGS will focus on meeting compliance and security requirements in the public sector. Some of the services the new entity will offer include:

  • Inventory management
  • Cold-chain and specialty storage for pharmaceuticals, medical devices and regulated goods
  • Enterprise-grade supply chain software
  • Government-compliant webstores and online ordering portals
  • Cybersecurity operations

Cart.com has been serving the public sector since 2022, when the company began distributing COVID-19 health supplies nationwide, according to the news release. Through that pandemic-era contract, the company reports it moved more than 725 million units, with an average of under two days per shipment.

Cart.com was founded in Houston in 2020, though it briefly moved its headquarters to Austin. The company reached unicorn status with its $60 million Series C raise in 2023. It most recently raised $180 million in growth capital from private equity firm Springcoast Partners in March, which put the startup over the $1 billion in fundraising mark in just six years.

At the time, Cart.com said it planned to scale its logistics network, expand AI capabilities and develop workflow automation tools.

Houston-based KBR Inc. also recently launched a government services spinoff. Read more here.

2 Houston universities named best colleges of 2027 by Princeton Review

A-Plus Ratings

Back-to-school season is has returned in full force, and that means it's time for college rankings. Two Houston universities in particular are being hailed as the top of the class for 2027.

The high caliber schools — Rice University and University of Houston — earned new acclaim in The Princeton Review's ranking of the "Best 392 Colleges" for 2027.

The Princeton Review's 35th annual "Best Colleges" rankings are determined by a survey of 172,000 current college students that gave "candid feedback" about their schools and their experiences. The flagship guide does not rank the schools overall, but it does rank them across 50 different categories, including best-run colleges, best quality of life, happiest students, best athletic facilities, among others.

In all, 14 Texas institutions were highlighted in the overall list of the 392 best colleges.

Schools don't pay to be included in the guide, but The Princeton Review clarified that schools could pay for a "featured" designation. No Houston university paid to be featured in this year's guide. Trinity University in San Antonio and Southwestern University, a private school in the Austin suburb Georgetown, were the only two Texas schools that paid to be "featured."

Rice and UH have been on a winning streak in separate reports of the best universities worldwide, best graduate schools, and best online degree programs.

In addition to being included in the overall list, Rice was highlighted as one of the Best Value Colleges, Colleges That Create Futures, and it earned high marks in Princeton Review's Mental Health Honor Roll 2026. The home of the Rice Owls also starred in the regional Best Southwest list that contained 41 universities across Arizona, Colorado, New Mexico, Oklahoma, and Texas.

"Rice University stands out as a leading research university where academic diversity and a wide array of interdisciplinary institutes and centers make it easy for students to explore multiple areas of interest," the school's profile says. "At Rice, 'knowledge isn’t siloed — students are constantly crossing disciplines and interests in ways that feel natural rather than exceptional.'"

Rice earned the following rankings on 14 other lists:

  • No. 1 – Lots of Race/Class Interaction
  • No. 3 – Best College Newspaper
  • No. 9 – Friendliest Students
  • No. 11 – Best Quality of Life
  • No. 13 – Great Financial Aid
  • No. 14 – Top 50 Best Value Private Colleges
  • No. 17 – Their Students Love These Colleges
  • No. 18 – Top 20 Best Value Private Colleges Without Aid
  • No. 18 – Best Student Support and Counseling Services
  • No. 19 – Best College Dorms
  • No. 21 – Students Study the Most
  • No. 24 – Best Campus Food
  • No. 24 – Best College Radio Station
  • No. 24 – Best-Run colleges
The University of Houston also appeared in the Best Southwest, Best Value Colleges, and Colleges That Create Futures lists, and it was named a top Green College, which examined schools that "share superb sustainability practices, a strong foundation in sustainability education, and a healthy quality of life for students on campus

UH earned five more accolades:

  • No. 1 – Top 50 Undergraduate Schools for Entrepreneurship Studies
  • No. 1 – Top Undergraduate Schools for Entrepreneurship Studies in the Southwest
  • No. 8 – Most Politically Moderate Students
  • No. 15 – Financial Aid Not So Great
  • No. 42 – Top 50 Best Value Public Colleges
In the school's profile, students say they had an overall positive experience thanks to UH's excellent academic offerings and dedicated faculty members.

"Students confirm that 'the research and other academic opportunities... are very accessible to students who seek it out,'" the profile says. "This includes taking advantage of UH’s vast alumni network (more than 325,000 and counting), not to mention its location in the corporate center of Houston, where 'the opportunities that are provided are immense.'"

The 12 other public and private universities in Texas included in The Princeton Review's 2027 guide are:

  • The University of Texas at Austin
  • Southwestern University, Georgetown
  • Baylor University, Waco
  • Texas A&M University - College Station
  • Trinity University, San Antonio
  • Texas State University, San Marcos
  • Angelo State University, San Angelo
  • Texas Christian University, Fort Worth
  • University of Dallas, Irving
  • Southern Methodist University, Dallas
  • The University of Texas at Dallas, Richardson
  • Austin College, Sherman
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A version of this story originally appeared on CultureMap.com.

Houston named the No.1 emerging city for biopharma in inaugural report

Biopharma Leader

Houston is ranked No.1 on the first-ever Next 10 U.S. Biopharma Clusters report published by Genetic Engineering & Biotechnology News (GEN).

The report, which ranks the best emerging hubs for life science activities, considered patents, NIH funding, lab space, venture capital investments, and the number of jobs in regions in cities, states and “clusters” across the U.S. GEN touts Houston as the top city for the biopharma industry due to a surge in funding, job creation, medical innovations and startup success.

Here’s how Houston ranked in the report’s different categories;

  • No. 1 for NIH funding with 2,262 awards totaling more than $1.25 billion
  • No. 2 for emerging regions for jobs, with 28,000 jobs
  • No. 2 for lab space, with roughly 8 million square feet in the market
  • No. 6 for patents, with 2,760 patent families

According to BioHouston chairman Jeff Wade, Houston secured half a billion dollars in venture capital funding in 2025 and 2026 to date.

The report called out major biopharm news out of Houston in the last few months, including Bristol Myers Squibb selecting Houston for its $1 billion, 600,000-square-foot manufacturing site and Eli Lily selecting Houston for its $6.5 billion, 236-acre manufacturing site. Both facilities will be located within Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston.

Houston startups like CrossBridge Bio and Duracyte were also mentioned in the report. CrossBridge, which develops antibody-drug conjugates for cancer, was acquired by Eli Lily in April for $300 million. Duracyte, a “living pharmacy” company, was launched out of Rice University’s biotech venture studio RBL LLC this spring and is backed by up to a $45 million Advanced Research Projects Agency for Health (ARPA-H) award.

The startup is working to commercialize its Hybrid Advanced Molecular Manufacturing Regulator (HAMMR) technology, a rechargeable, implantable device that can sense biological signals, monitor tumor environments and adjust therapeutic output in real time.

“There’s a lot of great talent, but the unique advantage that we have is we are able to benefit from a lot of unique clinical infrastructure and clinician insights,” Omid Veiseh, Duracyte co-founder and managing partner of RBL LLC, told GEN. “There are a lot of clinicians here who are eager to partner on investigator-initiated trials.”

The report also touted Houston’s Texas Medical Center, home to the University of Texas MD Anderson Cancer Center and Baylor College of Medicine, and international partnerships like the recently expanded TMC Korea BioBridge.

Other cities to make the list include:

  • No. 2 Minneapolis-St. Paul
  • No. 3 Denver-Boulder
  • No. 4 St. Louis
  • No. 5 Dallas-Fort Worth

States to make the list include:

  • No. 1 Ohio (including Cincinnati, Cleveland, and Columbus)
  • No. 2 Indiana (including Indianapolis)
  • No. 3 Florida (including Jacksonville and Miami-Fort Lauderdale)
  • No. 4 Georgia (including Atlanta and Augusta)
  • No. 5 Wisconsin (including Madison and Kenosha)

Regional state clusters to watch include:

  • Phoenix
  • Pittsburgh
  • Greater Richmond, Virginia
  • South Carolina
  • Utah

See the full report here.