Innovative shoewear, luxury EV charging, and more — all this innovation and more is coming out of Houston startups. Courtesy photos

Editor's note: As 2022 comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. This past year, InnovationMap featured profiles on dozens of these Houston startups — from sportstech apps and health tech companies to startups with solutions in EV tech and more. Here are five Houston startup features that stood out to readers this year — be sure to click through to read the full story.

Houston-based health tech startup is revolutionizing patient selection for clinical trials

Sieve Health is an AI cloud-based SaaS platform designed to automate and accelerate matching patients with clinical trials. Photo via Getty Images

On many occasions in her early career, Dr. Arti Bhosale, co-founder and CEO of Sieve Health, found herself frustrated with having to manually sift through thousands of digital files.

The documents, each containing the medical records of a patient seeking advanced treatment through a clinical trial, were always there to review — and there were always more to read.

Despite the tediousness of prescreening, which could take years, the idea of missing a patient and not giving them the opportunity to go through a potentially life-altering trial is what kept her going. The one she didn’t read could have slipped through the cracks and potentially not given someone care they needed.

“Those stories have stayed with me,” she says. “That’s why we developed Sieve.” Read more.

Houston startup snags prestigious grant from global health leader

Houston-based medical device and biotech startup Steradian Technologies has been recognized by the Bill and Melinda Gates Foundation. Photo by Dwight C. Andrews/Greater Houston Convention and Visitors Bureau

A female-founded biotech startup has announced that it has received a grant from the Bill & Melinda Gates Foundation.

Steradian Technologies has developed a breath-based collection device that can be used with diagnostic testing systems. Called RUMI, the device is non-invasive and fully portable and, according to a news release, costs the price of a latte.

“We are extremely honored to receive this award and be recognized by the Bill & Melinda Gates Foundation, a leader in global health. This funding will propel our work in creating deep-tech diagnostics and products to close the equity gap in global public health," says Asma Mirza, CEO and co-founder of Steradian Technologies, in the release. “The RUMI will demonstrate that advanced technology can be delivered to all areas of the world, ensuring the Global South and economically exploited regions receive access to high-fidelity diagnostics instead of solutions that are ill-suited to the environment.” Read more.

Houston sports tech startup is enhancing performance metrics for runners and athletes

Houston-based AiKYNETIX is equipping runners with high-tech tracking tools. Image courtesy of AiKYNETIX

With the Houston Marathon only five months away, a new application using human motion insights could help a runner refine their form to reach peak performance – all from the convenience of their smart phone.

While traditional treadmills are limited in training feedback and wearables are not designed to track elevation, Houston-based AiKYNETIX uses real-time technology to provide a new option for runners on treadmills.

“Runners spend a lot of time, energy and money to run better,” says Denis Akhiyarov, CEO and co-founder. “In my personal life with training for nine marathons, I’ve seen limitations with wearables, they don’t actually track running form while running. Overall, our technology tracks not only your basic parameters but it can also analyze the human running form while in motion.” Read more.

Local startup to upgrade EV charging in Houston and beyond

Houston-based Spark Spaces is looking to build out luxury spots for electric vehicle charging. Rendering courtesy of Spark Spaces

At 3 a.m. one night, just as he had many nights before, Tarun Girish found himself leaving his Houston apartment in search of an EV charger.

Once he located one, he would sit in his car for an hour and a half while his vehicle charged — with not much to do but wait.

But it was on this night he wondered if there was a way to use his previous hospitality experience to build a new kind of experience for EV drivers. He then developed his first iteration of a business plan — all while sitting in his driver’s seat.

His idea became Sparks Spaces, a startup formed in 2021 looking to shake up the EV charging game — the company aims to elevate the experience of charging electric vehicles by focusing on the space between car and charger by creating an airport lounge-type space for drivers. These EV lounges would include luxury waiting areas, clean restrooms, high-end food options, and availability to utilize them 24/7. Read more.

Houston neuroscientist turned startup founder takes steps toward comfier shoes

Steffie Tomson founded a company to prioritize comfort — without sacrificing style — for women on the go. Photo via getawaysticks.com

Two and half years ago, native Houstonian Steffie Tomson ordered $2,000 worth of shoes and sliced them all in half with a bandsaw just to see what was inside.

Tomson, a neuroscientist by trade and the founder and CEO of footwear startup Getaway Sticks, had an idea for a different kind of shoe — one that was redesigned to prioritize women’s comfort.

“I thought, ‘why can’t we start with a sneaker material and then build a heel around it?’” she tells InnovationMap. “I started just slicing everyone else’s shoes and now I’m more convinced than ever that our shoe is different.” Read more.

Support Houston startups by shopping local this holiday season. Photos courtesy

Startup gift guide: Shop local from these Houston companies

startup santa

'Tis the season for giving — and what if you could check off your holiday to-do list and simultaneously support some local startups? This year's Houston startup gift guide includes comfortable-yet-stylish heels, culinary treats, and more.

Need some more ideas? Browse last year's roundup of Houston startup-created gift ideas and check out the 2020 and 2019 startup gift guides as well for even more options.

For the family fashionista: All-day comfort shoes

Steffie Tomson founded a company to prioritize comfort — without sacrificing style — for women on the go. Photo via getawaysticks.com

Before starting her business, Houstonian Steffie Tomson ordered $2,000 worth of shoes and sliced them all in half with a bandsaw just to see what was inside. Tomson, a neuroscientist by trade and the founder and CEO of footwear startup Getaway Sticks, had an idea for a different kind of shoe — one that was redesigned to prioritize women’s comfort.

Earlier this year, Tomson shared the Getaway Sticks origin story with InnovationMap. The heels are available online for around $200 per pair.

For the resident chef: Fresh fish delivered

Sugar Land-based Fish Fixe floated their seafood delivery service on Shark Tank last year. Photo via Shark Tank

Houstonians Melissa Harrington and Emily Castro saw how beneficial incorporating fish into your diet can be — so they decided to launch an easier way to do it. They launched Fish Fixe in 2017 to deliver seafood with easy-to-access instructions on storage and thawing — plus cooking recipes that take around 20 minutes.

The duo appeared on the 13th season of Shark Tank last year. In 2020, as InnovationMap reported, the company saw a 400-percent increase in sales. They pitched asking for $200,000 in investment. Lori Greiner, the "queen of QVC," took the bait — and 25 percent equity.

Shoppers can stock up on various boxes from $109 to $219, or opt for a gift card for their loved one.

For the health nut: Sustainably-sourced nutrients

A Houston-based fund has deployed capital into a local nutritional supplement business. Photo via Instagram

Houston--based iwi creates nutritional supplements for the brain and the heart — and they are doing it in a sustainable setting: algae farms. These football field-sized farms operate on desert land using just salt water and sand and produce algae sustainably — all while absorbing CO2. Miguel Calatayud, CEO of the company, tells InnovationMap that the farms even area able to reuse 98 percent of the water involved in the process. Earlier this year, iwi received an investment from a local group in an $8 million deal.

The company has almost a dozen options online for around $30 per canister of supplements.

For your aging loved ones: Afterlife planning and memory keeping

The Postage — a Houston-based company that's streamlining afterlife planning — has rolled out a new app. Photo courtesy of The Postage

There's a lot that goes into legacy and afterlife planning, and a Houston startup has emerged to make the process a whole lot easier. The Postage helps its users generate their wills and organize information to leave behind, the company's founder, Emily Cisek, shares with InnovationMap. The platform also every user to leave messages, photos, and memories in a digital vault that will stand the test of time.

Giving the gift of legacy planning can be an option for anyone in your family — from the grandparents to the newlyweds.

For someone seeking luscious locks: Hair growth tracking kit

This startup is making sure every follicle of hair on your head is counted. Photo via myhaircounts.com

While it might seem odd to gift someone a hair loss tracking kit, this product from a Houston company has helped many men and women suffering from hair density challenges. MyHairCounts created a hair density imaging kit and app based on proprietary and patent-pending software. The kit includes a variety of items such as scalp imaging guides, a comb, and gel to help individuals photograph their hair follicles at specified angles. Users then upload these photographs into the app for analyses which are delivered within 48 hours. These analyses inform the user whether or not their hair regrowth treatment is effective.

The kit itself is just $40 and available online. Users can work with the company on a longer hair growth plan, too.

Bonus: What to bring to the table

Support Houston startups by bringing these goodies to your next festive shindig. Photos courtesy

Sometimes your presence is the present, and if you're headed to some holiday dinner parties, here are some innovative ideas for the potluck.

  • Houston-based Dream Harvest Farming Co., a vertical indoor farming company producing leafy greens and herbs and delivering them locally to grocery stores in Texas and nearby states. Pick up Dream Harvest products at a Whole Foods location, and read more about the company.
  • This year has been a big one for the growing Bread Man Baking Co., as the company expanded from its 5,000-square-foot kitchen and moved its operations into a new 40,000-square-foot facility on the northeast side of Houston. Pick up some of the company's products at Whole Foods or HEB. Read more about the company.
  • A new, “hyperpure” oxygen-enriched water brand has rolled out in Houston in single-serve and subscription options. Dubbed HOW — Hyperpure Oxygenated Water — the award-winning super-filtered water (via a 14-level filtration process that removes impurities down to the nano-level .0001 microns) is now available at 35 specialty retailers around town. Read more about the company.

This week's roundup of Houston innovators includes Steffie Tomson of Getaway Sticks ad Ed Pettitt and Paresh Patel of InnoGrid. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from innovative merchandise to microgrid technology — recently making headlines in Houston innovation.

Steffie Tomson, founder of Getaway Sticks

Steffie Tomson founded a company to prioritize comfort — without sacrificing style — for women on the go. Photo via getawaysticks.com

Houstonian Steffie Tomson, a neuroscientist by trade and the founder and CEO of footwear startup Getaway Sticks, had an idea for a different kind of shoe — one that was redesigned to prioritize women’s comfort.

“I thought, ‘why can’t we start with a sneaker material and then build a heel around it?’” she tells InnovationMap. “I started just slicing everyone else’s shoes and now I’m more convinced than ever that our shoe is different.”

Tomson was inspired to design the inaugural shoe for Getaway Sticks after her own struggle with heels, walking in the bustling Texas Medical Center from building to building for meetings. As a mom of two and a problem solver, she knew there had to be a better mousetrap. Click here to read more.

Ed Pettitt and Paresh Patel join the Houston Innovators Podcast to discuss InnoGrid's potential impact on equitable power. Photos courtesy of InnoGrid

With an unstable energy grid, two Houstonians know at least one solution in the evolving energy industry: Microgrids.

Ed Pettitt and Paresh Patel co-founded InnoGrid, a social enterprise working to establish community microgrids in lower income areas — neighborhoods that are most at risk of devastating power outages.

"We want to convert the commercial microgrid model for low and moderate income and undresourced residential communities," Patel explains on the latest episode of the Houston Innovators Podcast. Click here to read more and stream the episode.


Steffie Tomson founded a company to prioritize comfort — without sacrificing style — for women on the go. Photo via getawaysticks.com

Houston neuroscientist turned startup founder takes steps toward comfier shoes

well heeled in comfort

Two and half years ago, native Houstonian Steffie Tomson ordered $2,000 worth of shoes and sliced them all in half with a bandsaw just to see what was inside.

Tomson, a neuroscientist by trade and the founder and CEO of footwear startup Getaway Sticks, had an idea for a different kind of shoe — one that was redesigned to prioritize women’s comfort.

“I thought, ‘why can’t we start with a sneaker material and then build a heel around it?’” she tells InnovationMap. “I started just slicing everyone else’s shoes and now I’m more convinced than ever that our shoe is different.”

Tomson was inspired to design the inaugural shoe for Getaway Sticks after her own struggle with heels, walking in the bustling Texas Medical Center from building to building for meetings. As a mom of two and a problem solver, she knew there had to be a better mousetrap.

“No other shoe offers this type of foam with the height that we offer it,” she says of the wedge-style shoe, which offers a wide toe box, soft suede material and limited height for stability and joint health.

The comfortable wedge is available in several colors. Photo via getawaysticks.com

With her scientist background, she would think about the “cognitive cycles” that get spent in dealing with schedules and matching corresponding footwear.

“’This shoe goes with this outfit, but does this shoe get me from this meeting back from the parking lot? Does it fit with the pant?’ It’s just an infinite decision tree of how to get your wardrobe aligned with the shoes — when all I ever wanted was a capsule collection of shoes that would just work for me all the time,” she says.

Typically, the fashion industry constructs shoes in a very traditional way, she says, and because of this, Tomson was met with much resistance from manufacturers to get the right materials for her prototype.

“I think there’s a lot of money that gets thrown around trying to get women to buy shoes,” says Tomson. “Those may or may not be comfortable. There’s just not enough being poured into getting women to buy shoes that’s really been designed for us with us in mind.”

Getaway Sticks went through the gBETA accelerator last spring, which helped springboard the company and connect Tomson with the local innovation ecosystem.

“There aren’t many people who are making shoes in Houston, but there’s a lot of support for cool ideas and novel thinking here,” she says. I’m glad that I’ve been made aware of them and invited into these groups.”

Now past its first pre-seed phase and prepping for its initial round of seed funding in 2023, Getaway Sticks is looking ahead at its next shoe launch in the coming months — the ballet flat.

“I think that we as women can identify with the fact that we all have a really beautiful pair of heels and they are almost certainly not going to be comfortable,” she says. “And we may have a really comfortable pair of heels, but they are not always the cutest thing in our wardrobe. We always have to kind of flip and decide. I just felt strongly that we needed something to make our lives simpler.”

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Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”

10+ Houston innovation leaders in the spotlight at SXSW 2026

where to be

Houston's innovation scene will be well represented at South by Southwest (SXSW) this month.

The week-long, Austin-based conference and festival will spotlight some of the Bayou City's leaders in health care, energy, space and more. The event kicks off today, March 12, and runs through March 18. The SXSW Innovation Conference will feature keynotes, workshops, mentoring sessions and more throughout various venues in the city.

Here's who to see and when and where to find them:

March 12

Aileen Allen, venture partner at Mercury Fund

Mentor Session from 4-5:15 p.m. at Hilton Austin Downtown

Allen will host a mentoring session focused on funding, marketing, advertising, PR and the future of work.

March 13

Heath Butler, partner at Mercury Fund

SXSW Pitch-Smart Cities, Transportation, Manufacturing & Logistics from 2:30-3:30 p.m. at the J.W. Marriott

Butler will judge five innovative startups as they pitch their solutions to advance smart cities, enhance transportation systems, modernize manufacturing, transform logistics, and strengthen government infrastructure and civic operations.

Jonathan Cirtain, CEO and president of Axiom Space

The Clock is Ticking for Space - Replacing the ISS from 4-5 p.m. at the J.W. Marriott

Cirtain will discuss Axiom's pursuit of building the world’s first commercial space station.

March 14

Jesse Martinez, founder and CEO of LSA Global

SXSW Pitch-Intelligent Systems, Robotics, & Multisensory Technology from 10-11 a.m. at the J.W. Marriott

Martinez will judge five innovative startups as they pitch their technologies that aim to enhance the way people connect, communicate and share unique life experiences with those around them in a digital ecosystem.

Jennifer Schmitt, head of operations at Rhythm Energy

Powering Texas with Reliable Integrated High-Demand Energy from 10-11 a.m. at Marlow

Schmitt will join a panel to discuss how EirGrid, the state-owned electric power transmission operator in Ireland, is pioneering solutions as the country works toward 80 percent renewable integration by 2030.

Saki Sasagawa, director of business development for JETRO Houston

Now is Japan's Time: Leading the Future with Deep Tech from 10-11 a.m. at the J.W. Marriott

Sasagawa joins a panel that will share real-time insights from diverse perspectives on the forefront of Japan’s deep tech and IP businesses.

March 15

Bosco Lai, CEO and co-founder of Little Place Labs

SXSW Pitch Alumni: Where Are They Now? from 10-11 a.m. at the J.W. Marriott

Lai joins a panel of four former SXSW Pitch winners to share how they leveraged the platform to take their startups to the next level.

Tara Karimi, cofounder and chief science and sustainability officer at Cemvita

South by South America: The Rise of Southern Brazil Tech from 2:30-3:30. p.m. at The Line

Karimi will participate in a panel to discuss how Rio Grande do Sul, Brazil's southernmost state, is attracting elite talent and AI infrastructure and share insights on navigating the next wave of South American tech growth.

March 16

Dr. Pavitra P. Krishnamani, emergency medicine physician at The University of Texas MD Anderson Cancer Center

Viva La Revolution: How the Digital Age is Transforming Wellness from 11:30 a.m.-12:30 p.m. at Hilton Austin Downtown

Krishnamani will discuss the latest advancements and policies that can accelerate the digital age of health care, such as wearables, telehealth and artificial intelligence.

March 18

Charlie Childs, co-founder and CEO of Intero Biosystems

Spinning Out: What It Takes to Build a University Startup from 2:30-3:30 p.m. at The Line

Childs will join founders who spun their companies out of the University of Michigan to share the real story of navigating IP, early capital, team building, market validation and the “valley of death.”

Dr. James Allison, regental chair of immunology and director of The Allison Institute at The University of Texas MD Anderson Cancer Center

Dr. Padmanee Sharma, professor in the Department of Genitourinary Medical Oncology, Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center

Beyond Checkpoints: Immunotherapy’s Next Act from 2:30-3:30 p.m. at the J.W. Marriott

Allison and Sharma will sit down with 21-year-old, Stage 4 cancer survivor Sharon Belvin and Time Magazine journalist Alice Park will discuss the future of immunotherapy and what challenges remain.

Last year, Houston startups Little Places Labs and Helix Earth won top prizes in their respective categories at the prestigious SXSW Pitch event, held this year from March 13-14. No Houston startups were named finalists to compete in this year's event.

NASA revamps Artemis moon landing program by modeling it after Apollo

To the moon

NASA is revamping its Artemis moon exploration program to make it more like the fast-paced Apollo program half a century ago, adding an extra practice flight before attempting a high-risk lunar landing with a crew in two years.

The overhaul in the flight lineup came just days after NASA’s new moon rocket returned to its hangar for more repairs, and a safety panel warned the space agency to scale back its overly ambitious goals for humanity’s first lunar landing since 1972.

Artemis II, a lunar fly-around by four astronauts, is off until at least April because of rocket problems.

The follow-up mission, Artemis III, had been targeting a landing near the moon’s south pole by another pair of astronauts in about three years. But with long gaps between flights and concern growing over the readiness of a lunar lander and moonwalking suits, NASA’s new administrator Jared Isaacman announced that mission would instead focus on launching a lunar lander into orbit around Earth in 2027 for docking practice by astronauts flying in an Orion capsule.

The new plan calls for a moon landing — potentially even two moon landings — by astronauts in 2028.

“Everybody agrees. This is the only way forward,” Isaacman said.

The hydrogen fuel leaks and helium flow problems that struck the Space Launch System rocket on the pad at NASA's Kennedy Space Center in February also plagued the first Artemis test flight without a crew in 2022.

Another three-year gap was looming between Artemis II and the moon landing by astronauts as originally envisioned, Isaacman said.

Isaacman stressed that “it should be incredibly obvious” that three years between flights is unacceptable. He'd like to get it down to one year or even less.

Isaacman, a tech billionaire who bought his own trips to orbit and performed the world’s first private spacewalk, took the helm at NASA in December.

During NASA’s storied Apollo program, he said, astronauts’ first flight to the moon was followed by two more missions before Neil Armstrong and Buzz Aldrin landed on the moon. What's more, he added, the Apollo moonshots followed one another in quick succession, just as the earlier Projects Mercury and Gemini had rapid flight rates, sometimes coming just a few months apart.

Twenty-four Apollo astronauts flew to the moon from 1968 through 1972, with 12 of them landing.

“No one at NASA forgot their history books. They knew how to do this," Isaacman said. “Now we're putting it in action.”

To pick up the pace and reduce risk, NASA will standardize its Space Launch System rockets moving forward, Isaacman said. These are the massive rockets that will launch astronauts to the moon aboard Orion capsules. At the same time, Elon Musk's SpaceX and Jeff Bezos' Blue Origin are speeding up their work on the landers needed to get the astronauts from lunar orbit down to the surface.

Isaacman said next year will see an Orion crew rendezvousing in orbit around Earth with SpaceX's Starship, Blue Origin's Blue Moon or both landers. It's similar to the methodical approach that worked so well during Apollo in the late 1960s, he noted. Apollo 8, astronauts' first flight to the moon, was followed by two more missions before Armstrong and Aldrin aimed for the lunar surface.

“We should be getting back to basics and doing what we know works,” he said.

The Aerospace Safety Advisory Panel recommended that NASA revise its objectives for Artemis III “given the demanding mission goals.” It’s urgent the space agency do that, the panel said, if the United States hopes to safely return astronauts to the moon. Isaacman said the revised Artemis flight plan addresses the panel's concerns and is supported by industry and the Trump administration.