This week's innovators to know are all tech entrepreneurs with big ideas. Courtesy photos

3 Houston innovators to know this week

Who's who

From the science of love to confusing cryptocurrency, this week's Houston innovators to know are dabbling in some interesting industries to say the least.

Corey Allen, founder of Ecotone and treasurer of the Greater Houston LGBT Chamber

Corey Allen had entrepreneurialism in his blood — but it wasn't until he got involved with the Greater Houston LGBT Chamber that he got the courage to break out on his own. Courtesy of Corey Allen

This week's Pride Month feature is Corey Allen, who has an amazing storing into entrepreneurialism. He found confidence and encouragement from joining the LGBT chamber and started his own business. Now, he helps lead the organization as treasurer. Click here to read his Q&A with InnovationMap.

Brittany Barreto, CEO and co-founder of WeHaveChemistry

Brittany Barreto has expanded her DNA dating technology to a compatibility company named We Have Chemistry. Courtesy of WeHaveChemistry

As Brittany Barreto was working to use science to find singles love, she fielded many requests from couples who wanted in on the DNA compatibility tool she created. The requests kept coming in and now, Barreto has pivoted her dating app, Pheramor, to a new compatibility concept called WeHaveChemistry. Click here to read the full story.

Spencer Randall, principal and co-founder of CryptoEQ

Cryptocurrency doesn't have to be a big, confusing risk with this Houston startup's technology. Courtesy of CryptoEQ

Spencer Randall, through his new company CryptoEQ, wants to simplify ratings and analysis in cryptocurrency, which historically has been confusing and approachable to most. With the company's beta now live, Randall hopes that those not familiar with cryptocurrency will be able to use the platform as a learning tool. The platform takes information on trending cryptocurrency and boils it down into three columns — rating, technical analysis and trend analysis — in order for users to know when to buy or sell. Read the full story here.

Corey Allen had entrepreneurialism in his blood — but it wasn't until he got involved with the Greater Houston LGBT Chamber that he got the courage to break out on his own. Courtesy of Corey Allen

Houston entrepreneur explains how he's seen the city's LGBT and innovation communities evolve

Featured Innovator

Corey Allen grew up surrounded by entrepreneurship. His family owned several small businesses when he was growing up. But it took the support of his community to push him toward leadership.

From working in an accounting firm to dabbling in a few oil and gas companies, Allen's career trajectory changed when he joined the Greater Houston LGBT Chamber of Commerce. Within the organization, for which he serves as treasurer, he met other motivated entrepreneurs and was given the support needed to open his own business, Ecotone.

Allen spoke with InnovationMap about his career and the importance of the LGBTQ community in entrepreneurship.

InnovationMap: How does Houston differ from other cities in the U.S. in terms of technology and entrepreneurship? What makes Houston different?

Corey Allen: I think everybody does default to Austin, right? People believe that that's the only technology hub in Texas. Houston is new and different from other cities in terms of tech and entrepreneurship, right now especially. In creating three local startups, we experienced tremendous support from well-established groups like the Greater Houston Partnership, the city of Houston with the Mayor's entrepreneurship program, the Greater Houston Chamber of Commerce. But, you know, what I think what is really new especially for Texas, within in Houston, is the local coworking spaces that are globally recognized brands and the coding camps. I think that is what is creating the infrastructure and ecosystem that we've been talking about for the last five years at least. I think that compared to other cities in the U.S., I don't see that type of energy and that type of investment being created in Houston right now.

IM: You mentioned a little bit about being involved in the process of creating three local startups. What makes Houston the right place to be involved in the startup culture that’s cultivating right now?

CA: I think there's two things that come to mind. Houston really is home, and it's always been home for me. And it really is a big, small town. I came from a small town in Texas, about halfway between Houston and Dallas, and our family always navigated to Houston for fun, but also for business. It was really the foundation for my own family, and I think what we get out of Houston is that southern hospitality is a real thing. So, that's certainly the first thing. And the second is that Houston has the foundation for a prosperous ecosystem. Obviously, there's a lot of oil and gas and the Texas Medical Center is already globally recognized. The more that we continue to focus on venture capital and innovation, which is what is wanted and needed right now, Houston is creating our own new technology and entrepreneurship to capture everybody's attention.

IM: What are some of the ways the tech and innovation community support their LGBTQ colleagues throughout the month of June?

Yeah, I love this question. I think it goes without saying for the community to come out and support the LGBTQ community by joining the chamber of commerce. Also, attending our second annual Pride in Business, which is June 28. That's been an outstanding event for all of the businesses in the community to be involved in the LGBT community. In three years time, (the Greater Houston LGBT Chamber) has been growing exponentially to over 125 visible members. And we have corporate partnerships that really speak to the impact that is being made in the community and in Houston. We have corporate partners like Shell and United. And also celebrate and attend the Houston Pride Parade, which is on June 22.

IM: What advice do you have for up-and-coming lgbtq entrepreneurs?

CA: The learning is the action. I used to really be annoyed by the phrase "sell faster." I actually live that now. You can't fail until you act, and now I know that you can't compete until you fail.

IM: That's great advice right there. What does pride month mean to you?

CA: It's very personal, and it hits home. My partner and I are going to be celebrating 19 years together in September, and I think that pride means celebrating a history that we don't stop to think about everyday. We were at a chamber meeting recently, and a member was sharing her experience of walking in the second pride parade. And she said that it wasn't the same. Even the police at the time did not protect the community. And that's a big difference from today. And I think anybody that goes out to the pride parade this year, I want them to know they're safe. And you know, I think that that's what we have to be thankful for today is to know that we can love without constant fear. It really just reminds us that we're not going to let anyone take that away again.

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Portions of this interview have been edited.

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Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

Aegis Aerospace appoints Houston space leader as new president

moving up

Houston-based Aegis Aerospace's current chief strategy officer, Matt Ondler, will take on the additional role of president on Jan. 1. Ondler will succeed Bill Hollister, who is retiring.

“Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers,” Stephanie Murphy, CEO of Aegis Aerospace, said in a news release.

Hollister guided Aegis Aerospace through expansion and innovation in his three years as president, and will continue to serve in the role of chief technology officer (CTO) for six months and focus on the company's technical and intellectual property frameworks.

"Bill has played an instrumental role in shaping the success and growth of our company, and his contributions leave an indelible mark on both our culture and our achievements," Murphy said in a news release.

Ondler has a background in space hardware development and strategic leadership in government and commercial sectors. Ondler founded subsea robots and software company Houston Mechatronics, Inc., now known as Nauticus Robotics, and also served as president, CTO and CSO during a five-year tenure at Axiom Space. He held various roles in his 25 years at NASA and was also named to the Texas Aerospace Research and Space Economy Consortium Executive Committee last year.

"I am confident that with Matt at the helm as president and Bill supporting us as CTO, we will continue to build on our strong foundation and further elevate our impact in the space industry," Murphy said in a news release. "Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers."

Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

neuro research

Rice University launched its new Amyloid Mechanism and Disease Center last month, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases.

The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established.

The team will work to ultimately increase its understanding of amyloid processes and will collaborate with the Texas Medical Center to turn lab discoveries into real progress for patients. It will hold its launch event on Jan. 21, 2026, and hopes to eventually be a launchpad for future external research funding.

The new hub will be led by Pernilla Wittung-Stafshed, a Rice biophysicist and the Charles W. Duncan Jr.-Welch Chair in Chemistry.

“To make a real difference, we have to go all the way and find a cure,” Wittung-Stafshede said in a news release. “At Rice, with the Amyloid Mechanism and Disease Center as a catalyst, we have the people and ideas to open new doors toward solutions.”

Wittung-Stafshede, who was recruited to Rice through a Cancer Prevention and Research Institute of Texas grant this summer, has led pioneering work on how metal-binding proteins impact neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Her most recent study, published in Advanced Science, suggests a new way of understanding how amyloids may harm cells and consume the brain’s energy molecule, ATP.

According to Alzheimer’s Disease International, neurodegenerative disease cases could reach around 78 million by 2030 and 139 million by 2050. Wittung-Stafshede’s father died of dementia several years ago.

“This is close to my heart,” Wittung-Stafshede added in the news release. “Neurodegenerative diseases such as dementia, Alzheimer’s and Parkinson’s are on the rise as people live longer, and age is the largest risk factor. It affects everyone.”