The Cannon is opening a new location just down the road from its headquarters. Photo courtesy of The Cannon

The Cannon has announced its latest coworking location, and it's not too far from where the company's original facility launched.

The Cannon Memorial is expected to open this spring in Two Memorial City Plaza (820 Gessner) within MetroNational's Memorial City, a 265-acre planned development in west Houston. The coworking concept will take up one floor with 21,960 square feet of space.

"We are delighted to unveil The Cannon Memorial as a pivotal addition to Houston's dynamic business landscape," Jon Lambert, CEO of The Cannon, says in a news release. "Our expansion into Two Memorial City Plaza aligns seamlessly with our mission to cultivate innovation, collaboration, and success within the business community. We eagerly anticipate welcoming entrepreneurs and professionals to experience the unparalleled environment we've created."

The new location is less than three miles from The Cannon West Houston (1334 Brittmoore Rd) and will feature:

  • 38 private office spaces
  • accomodations for over 60 flex users
  • 24/7 access for members
  • free covered parking in the attached garage
  • programmed events, workshops, and networking sessions

“MetroNational is thrilled that The Cannon Memorial is opening and is another exciting milestone in our continued commitment to constantly elevate and enhance the services and experiences at Memorial City,” Anne Marie Ratliff, vice president of Asset Management at MetroNational, says in the release. “This partnership represents not just a collaboration but a testament to our dedication to staying at the forefront of innovation.”

The Cannon — founded in 2017 by Lawson Gow, the son of David Gow, founder of InnovationMap's parent company, Gow Media — has a presence in seven of Houston's regions, including west Houston, downtown, uptown, Fish Creek, The Woodlands, Pearland, and Galveston.

Lawson Gow, CEO and founder of The Cannon, has officially opened cut the ribbon on the West Houston startup incubation hub. Courtesy of Quy Tran/The Cannon

Photos: The Cannon Houston makes grand debut with live fundraising and immersive activities

Open for business

The coworking and acceleration hub that's been holding down the Houston innovation ecosystem's West Houston presence has officially cut the ribbon and celebrated its grand opening.

Just hours after announcing The Downtown Launch Pad on October 24, The Cannon Houston celebrated the grand opening of its 120,0000-square-foot home at 1334 Brittmoore Road. The party welcomed over 600 innovators, Cannon members, and visitors.

Founder and CEO, Lawson Gow, who is also the son of InnovationMap's parent company's CEO, cut the ribbon on the new building that houses over 250 companies and is nearly sold out for leasing opportunities.

"It's been incredible watching The Cannon come to life since it was a drawing on a whiteboard," says Gow in a news release. "There are far too many people to thank — from the first community members that joined us in The Waiting Room more than 18 months ago, the numerous partners, investors, ecosystem members and resources that have helped us get where we are today, all the way to our new members who patiently waited for the space to open."

Gow's "Waiting Room" building is still in existence adjacent to the new building — the landlord of the property is operating it, but Cannon companies have all moved in to the new facility.

The grand opening event showcased all the startups and entrepreneurs based in The Cannon, plus hosted mental breaks — with free massages and cuddles with dogs — and other activities like poker and pingpong.

One Cannon-based startup, LetsLaunch, even hosted a live pitch event for a few of the companies using its digital investment platform, including: Camppedia, Social Chains, Pill Golf, and Paylight. Since the live pitch last week, LetsLaunch has seen a $21,000 increase of investment online.

While The Cannon team is settled, the organization already has growth and expansion in the works.

"Each person had a major part in getting us where we are today," Gow says. "We knew that Houston was in desperate need of a resource like this and are thankful to be able to build this community and fulfill our mission of supporting Houston's entrepreneurs."

Off with a blast

Courtesy of Quy Tran/The Cannon

The Cannon welcomed in over 600 members, staff, and guests into its new home on Thursday, October 24.

Amazon has invested over $10 billion into Texas since 2010. Photo via blog.aboutamazon.com

Amazon opens newest Tech Hub in Houston and plans to hire

It's 'zon

A year and a half after Houston was left off the list of 20 cities Amazon was pursuing for its second United States headquarters, the tech giant chose the Bayou City to house its 18th North American Tech Hub.

Amazon opened the doors of the hub on Friday, July 26, in 25,000-square-feet of space in CITYCENTRE, and the company has plans to hire to round out its team of 150 Amazon Web Services employees to work out of the hub.

"We're looking forward to becoming a bigger part of the Houston community," says Kris Satterthwaite, Gulf Coast enterprise sales leader of AWS, in a release. "Houston is a fantastic place to live and work, and has a strong local economy that we look forward to investing in and growing together."

The city of Houston, along with the Greater Houston Partnership, has worked to make Houston appealing to big business and tech giants, says Susan Davenport, senior vice president of economic development at the GHP.

"The expansion of Amazon's Houston workforce is indicative of a larger trend we are seeing of the major cloud players opting to locate their teams closer to their customers here in Houston," Davenport says in an email to InnovationMap. "Our energy, life sciences and manufacturing sectors are data-intensive, and this move makes a lot of sense. This is not the first, and I doubt it will be the last. A great portion of the digital tech industry's activity to this point has been focused on business-to-consumer, and is now shifting to business-to-business. Houston is largely a B2B city, so we stand to gain from this trend."

The Tech Hubs in North America have over 20,000 employees. Around 1,000 of those are from Amazon's Austin Tech Hub, which opened around four years ago and was recently announced to be in the process of expanding to include another 800 Austin employees, per the Wall Street Journal.

The company has invested $10 billion into Texas since 2010, according to the release, and Houston's diversity, universities, and quality of life were attractive to Amazon.

"Houston is such a culturally diverse city, with so many international companies based here," says Eddie Murray, global accounts lead, in a release. "We're excited to create great jobs and hire locally to boost the local economy while also giving back to the community through programs like Amazon Future Engineer."

The Amazon Future Engineer program is an initiative to help propel kids from under-served areas into careers in computer science. The program is in 35 Houston schools. Amazon also provided disaster relief aid after Hurricane Harvey in 2017.

"We have worked for the last couple of years to accelerate the growth of Houston's digital tech ecosystem, and we've got quite a bit of momentum with The Ion, TMC3, The Cannon, and so many others," Davenport adds. "The opening of Amazon's tech hub is another indicator of Houston's growing presence as an innovation-focused city."

The Cannon's new building is 88 percent leased and ready for move in. Courtesy of The Cannon

Photos: The Cannon unveils its 120,000-square-foot startup hub in West Houston

Homecoming

The Cannon is finally getting to move its 150 startups and partners into its 120,000-square-foot campus in West Houston.

The original plan was to open in March, but construction, which began in April 2018, faced a series of setbacks due to weather. Current grand opening celebration plans are expected to be in September.

The flagship building is just the first step developing the campus, which is dubbed the Founders District.

"Our team has worked tirelessly to build this community over the past eighteen months, and we are incredibly proud to see our vision coming to life with the completion of this building," says The Cannon's CEO Lawson Gow in a news release. "The work isn't over though, and The Cannon will continue to grow our network of resources and locations to cater to the needs of Houston's growing entrepreneurial community." (Gow is the son of David Gow, owner of InnovationMap's parent company Gow Media.)

The building is currently 88 percent leased. Cannon Ventures, the company's investor group, will operate out of the new building, as will Capital Factory's Houston outpost. Austin-based Capital Factory, a statewide startup accelerator announced it would have its Houston operations at The Cannon in May. Since then, the company hired two Houston-based employees to run the programming.

According to the release, The Cannon will continue to grow its community relations for a "full suite" of partners. Houston-based investment fund Work America Capital, which led The Cannon's initial fundraising round, will also be joining The Cannon's community in the new building.

"It has been incredible to watch The Cannon's exceptional growth from inception two years ago to the vibrant community they've built today," says Mark Toon, managing partner of Work America Capital, in the release. "We can't wait to see the progress first-hand as The Cannon continues to establish themselves as a leader in building entrepreneurial communities."

The Cannon previously operated out of a 20,000-square-foot adjacent building called "The Waiting Room," which will be torn down and the space will be used as a part of the bigger Founders District plan.

The Cannon's new space will feature:

  • A 16-TV video wall
  • Outdoor courtyard
  • Movie theater
  • Snacks, coffee, and beer
  • Office needs, such as printers, scanners, and mail services
  • Showers
  • 24/7 accessibility
  • Professional and social events are organized on an ongoing basis for the community
  • Private event hosting for both members and non-members

Spacious setting

Courtesy of The Cannon

The Cannon is currently 88 percent leased.

The Cannon's 120,000-square-foot space is on track to open March 1. Courtesy of The Cannon

Photos: West Houston coworking space 50 percent leased ahead of early 2019 opening

Ready, aim, fire

Everything's bigger in Texas, and Houston will soon have a coworking space to reflect that. The Cannon is on track to open its West Houston 120,000-square-foot, 32-acre coworking and entrepreneurship campus by March 1.

"We're going to have, as far as I know, the biggest coworking space in the world," says Lawson Gow, founder and CEO of The Cannon. "It's a really Houston-sized solution to the problem of the challenge we set out to face."

The construction broke ground in April, and Gow — son of David Gow, owner of InnovationMap's parent company Gow Media — says they haven't seen any real delays so far. The new space will have 11 meeting rooms, sound-proof phone booths, 24-hour access, health and wellness room, courtyard, movie theater, a gameroom, and more to offer its coworkers.

Currently, The Cannon's coworkers are functioning out of a 20,000-square-foot space at 1336 Brittmoore Road, also known as the waiting room, which is adjacent to the construction.

The Cannon has 50 percent of the new space already leased — and Gow says about 75 percent of the pre-leased companies are already companies working out of The Cannon. Gow says he's just started doing some promotion around leasing — hard hat happy hours and tours — but he's not too worried about being 100 percent leased. He just wants to make sure there are enough companies in there by opening day.

"We've painstakingly created the culture of the community in The Cannon in the space we're in now, and we have to do that all over again," Gow says. "We want to have the hustle and bustle in the space, and you can't do that if it's empty."

Two Houston-based companies are responsible for the project; Burton Construction is the general contractor and Abel Design Group is the architect.

A few years ago, Gow says he recognized a need in Houston — and The Cannon was his solution.

"The problem that we're addressing — every startup is addressing a problem — is Houston has really struggled to develop vibrant startup communities," Gow says. "Entrepreneurs and talent will leave to go to Austin and beyond, and so the mission was to create a place and an infrastructure and a density of resources to prevent them from having to do that and keep our entrepreneurs here."

Large and in charge

Courtesy of The Cannon

The new Cannon facility will be the largest coworking space in Houston, says Lawson Gow, founder and CEO of The Cannon.

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Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

     
  • $1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
  • $922 million for the University of Houston System
  • $167 million for Texas Southern University
  • $10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

     
  • Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
  • Created the Lake Houston Dredging and Maintenance District
  • Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.