3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Spencer Randall of CryptoEQ, Andy Grolnick of Graylog, and Imran Alibhai of Tvardi. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from software to cryptocurrency — recently making headlines in Houston innovation.

Spencer Randall, co-founder and principal at CryptoEQ

Spencer Randall, principal and co-founder of CryptoEQ, joins the Houston Innovators Podcast to discuss how his company has grown alongside the cryptocurrency industry. Photo courtesy of CryptoEQ

It's an interesting time for cryptocurrency and no one knows that better than Spencer Randall, principal and co-founder of Houston-based CryptoEQ, a company that's built a platform for resources and information for everyone interested in cryptocurrency and digital assets.

"CryptoEQ is really built to be the North Star for digital asset research and information. We provide market insights for both newcomers and folks that are already well-versed in cryptocurrency and digital assets," Randall says on this week's of the Houston Innovators Podcast. "The idea of the company is to help shepherd folks along and guide them on their crypto journey."

Recently the company entered into a partnership with The Cannon, an entrepreneurial hub with locations across Houston, to provide a one-of-a-kind crypto starter pack to help onboard innovators to the cryptosphere worldwide. Click here to read more and stream the episode.

Andy Grolnick, CEO of Graylog

A Houston company that's created a centralized log management solution has closed a new round in funding. Photo courtesy of Graylog

Houston-based Graylog closed its $18 million growth equity round led by new investors Harbert Growth Partners and Piper Sandler Merchant Banking, as well as existing investors Houston-based Mercury Fund and Integr8d Capital.

"This investment will enable us to accelerate our global go-to-market strategies and enhancements to the award-winning solutions we deliver for IT, DevOps, and Security teams," says Andy Grolnick, CEO of Graylog, in a press release. "We're excited to have the support of new and existing investor partners to help us realize our potential." Click here to read more.

Imran Alibhai, CEO at Tvardi

Tvardi Therapeutics Inc. has fresh funds to support its drug's advancement in clinical trials. Photo courtesy of Tvardi

Houston-based, cancer-fighting company Tvardi Therapeutics Inc. closed its $74 million series B funding round led by new investors New York-based Slate Path Capital, Florida-based Palkon Capital, Denver-based ArrowMark Partners, and New York-based 683 Capital, with continued support and participation by existing investors, including Houston-based Sporos Bioventures.

"We are thrilled to move out of stealth mode and partner with this lineup of long-term institutional investors," says Imran Alibhai, CEO at Tvardi. "With this financing we are positioned to advance the clinical development of our small molecule inhibitors of STAT3 into mid-stage trials as well as grow our team." Click here to read more.

Spencer Randall, principal and co-founder of CryptoEQ, joins the Houston Innovators Podcast to discuss how his company has grown alongside the cryptocurrency industry. Photo courtesy of CryptoEQ

Houston startup shines bright as cryptocurrency's 'North Star'

Houston innovator's podcast episode 89

When Spencer Randall and his co-founders dreamt up the idea for CryptoEQ in 2018, they couldn't have even imagined how huge of a presence cryptocurrency would have in the world.

Within the past year, publicly traded companies holding Bitcoin on their balance sheet, El Salvador has announced its adopting Bitcoin as legal tender, dozens of other "altcoins" have emerged, and, as of earlier this month, thousands attended the biggest crypto event in the world.

Helping its users navigate it all is Houston-based CryptoEQ, which has, over the past 18 months, seen 10x growth in users and revenue — recently reaching the 30,000 user milestone.

"CryptoEQ is really built to be the North Star for digital asset research and information. We provide market insights for both newcomers and folks that are already well-versed in cryptocurrency and digital assets," Randall says on this week's of the Houston Innovators Podcast. "The idea of the company is to help shepherd folks along and guide them on their crypto journey."

The platform, which offers both free and paid membership, has expanded to be able to offer something for everyone, despite their cryptocurrency proficiency. In fact, recently the company entered into a partnership with The Cannon, an entrepreneurial hub with locations across Houston, to provide a one-of-a-kind crypto starter pack to help onboard innovators to the cryptosphere worldwide. The new offering launches this week.

"We have a lot of roots at the Cannon — we actually started building CryptoEQ at the original location of the Cannon. So, it's really cool to come full circle and buildout a crypto starter pack with the Cannon team," Randall says.

He shares more about the state of cryptocurrency and how he's seen his company grow on the episode. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


The Texas Medical Center is buzzing with recent innovation news, from Texas A&M University naming its buildings, Houston Methodist is introducing a new technology, and more. Photo by Dwight C. Andrews/Greater Houston Convention and Visitors Bureau

Startup closes series A, Houston hospital taps into new tech, and more local innovation news

short stories

Houston's innovation ecosystem has been booming with news, and it's likely some might have fallen through the cracks.

For this roundup of short stories within Houston innovation, Deloitte is looking for tech companies to honor, a few Houston innovators have fresh funds, buildings rising in the Texas Medical Center now have names, and more.

Texas A&M names buildings in Innovation Plaza

Texas A&M University has named the buildings that will be a part of its Innovation Plaza. Photo courtesy of Texas A&M University System

The Texas A&M University System has revealed the names of the three buildings in the Texas A&M Innovation Plaza rising near the Texas Medical Center: Discovery Tower, Life Tower, and Horizon Tower.

Discovery Tower is the future home of A&M's EnMed program and is currently being renovated from an 18-story office building. Life Tower, which is expected to deliver in June 2022, is a 19-story, 714-bed student housing tower for Texas A&M medical students and Prairie View A&M University nursing students. Lastly, the Horizon Tower will be a 17-story, 485,000 square-foot integrated building that will feature a 13-story parking structure at the bottom.

SecurityGate closes series A

Ted Gutierrez, CEO of SecurityGate, announced the closing of his company's series A. Courtesy of Security Gate

SecurityGate.io, a software-as-a-service cybersecurity startup based in Houston, has closed its series A fundraising round. Houston Ventures led the capital raise. The amount raised has not been disclosed.

"It was very attractive to us how tightly tuned SecurityGate.io is to the needs of their customers," says Chip Davis, managing partner at Houston Ventures, in a news release. "Successful enterprise software companies generally know they are instruments of change for their customers."

Davis says the feedback from SecurityGate's customers was what sealed the deal.

"Digital transformation is no easy task in highly dynamic environments, especially when the risk of cyberattacks keeps rising daily. We're excited to partner with Houston Ventures who sees this market growing, and our clients that see our vision of the future," says Ted Gutierrez, CEO of SecurityGate, in the release.

Well Health launches at Houston Methodist

Thanks to tech from the West Coast, a Houston hospital has optimized virtual visits. Courtesy of Methodist Hospital/Facebook

Through a partnership with California-based WELL Health Houston Methodist was able up the ante on virtual visits during the pandemic. According to a news release, WELL enabled Houston Methodist to deliver over 260,000 text messages to patients Houston Methodist. The messages educated them about virtual care, schedule visits, and more.

"The ability to communicate back and forth, assuring patients that we are here for them both virtually and in-person is crucial as we continue to safely provide care in the midst of this pandemic," says Tesha Montgomery, vice president of operations and patient access at Houston Methodist, in the release.

Houston podcast network raises over $1 million

A podcast network with Houston ties has raised a seed round. Pexels

Lemonada Media, a podcast network with Houston roots that launched in September, has raised $1.38 million in a seed funding round led by Blue Collective, an early-stage venture capital firm. The fresh funds will allow for strategic growth for the two co-founders, Jessica Cordova Kramer, CEO, and Houstonian Stephanie Wittels Wachs, chief creative officer. Lemonada also plans to hire several positions including vice presidents across finance, production, and marketing.

"We are slated to be a content and talent incubator, spinning out new audio concepts and hit series that present humanity, unfiltered," says Wittels Wachs in a news release. "Now more than ever, people are hungry for content that addresses their lived experience, those that are mundane, and those that may be painful and isolating. Because our company was built off a mountain of personal grief and loss, Lemonada is well-situated to cut through the noise, create beautiful works of art, and make people laugh and feel less alone along the way."

Deloitte is looking for tech companies for annual competition

For the 26th year, Deloitte is looking for cutting edge tech companies. Photo courtesy of Deloitte

Deloitte has opened applications for its 2020 Technology Fast 500. The application is available online and closes July 17. To be eligible for the award, the startup must be in business for a minimum of four years, have its headquarters in North America, have fiscal year 2016 operating revenues of at least $50,000, a fiscal year 2019 operating revenues of at least $5 million USD with a growth rate of 75 percent or greater, and own proprietary intellectual property or proprietary technology which must be sold to customers in products or services that contribute to a majority of the company's operating revenues, according to the contest's rules.

Companies should also fall within one of the following industry categories: biotechnology/pharmaceutical, communications/networking, digital content/media/entertainment, electronic devices/hardware, energy tech, medical devices, semiconductor, or software/SaaS.

Lazarus 3D delivers PPE to Haiti

A few Houston innovators have helped get Haitians critical PPE. Photo courtesy of Orolait

A few Houston innovators have helped connect health care workers in Haiti to some PPE. Ana Rojas Bastidas, founder of Orolait, and Jacques and Smriti Agrawal Zaneveld of Lazarus 3D, teamed up to ship over 1,000 pieces of PPE to United States Foundation for the Children of Haiti which supported orphanages, schools, and a hospital called Hopital Espoir.

In the middle of April, Bastidas saw the organization's need for PPE and saw how Lazarus 3D was creating materials. The group in Haiti received the supplies by the beginning of June.

"I'm really proud of the collaboration between myself and the Lazarus 3D team," Bastidas says. "Smriti and Jacques are absolute gems and while our businesses are completely separate, we found a common problem we both had the resources to tackle."

CryptoEQ begins offering consulting packages

Need custom cryptocurrency support? CryptoEQ is here to help. Courtesy of CryptoEQ

A cryptocurrency startup based in Houston has expanded its service to include custom-consulting packages.

"With our personalized packages, gain the market insights you need to refine your cryptocurrency investing and trading strategies," writes Spencer Randall, co-founder and principal of CryptoEQ.

The packages come at three levels: the enthusiast, the professional, and the expert. The individualized support begins at $499, and more information can be requested from the startup by emailing team@cryptoeq.io.

This week's Houston innovators to know include Dakota Stormer, founder of Footprint; Jonathan Wasserstrum, founder of SquareFoot; and Spencer Randall, co-founder and principal of CryptoEQ. Courtesy photos

3 Houston innovators to know this week

Who's who

Technology can make a huge difference, and Houston innovators are tapping into tech to disrupt various industries from real estate to sustainability.

This week's Houston innovators to know all have a focus on using tech tools to move the needle, whether it's to demystify cryptocurrency, track your ecological footprint, or find your next office space.

Dakota Stormer, founder of Footprint

Dakota Stormer created the Footprint app to help users be more conscientious of their personal contribution to climate change. Photo courtesy of Footprint

Dakota Stormer firmly believes that individuals can make a difference on climate change. And, maybe more importantly, individuals want to try to make that difference. So, he created an app to help. Footprint's algorithm calculates an annual carbon footprint, then averages it out to a per-week measure. This way, users know their goals — and the app sends them suggestions and challenges, like "meatless Mondays," to help reduce their emissions.

"For one person, it doesn't seem like there's much that you can do," Stormer says. "But the number of people across the world that care about climate change — it's actually a majority, at this point."

Click here to read more.

Jonathan Wasserstrum, founder and CEO of SquareFoot

SquareFoot — a real estate tech company with Houston roots — is entering the Houston market. Courtesy of SquareFoot

In 2011, Houston native Jonathan Wasserstrum founded SquareFoot to use tech tools to improve the commercial leasing experience in New York. Now, almost a decade later and fresh off of the closing of a $16 million series B funding round, SquareFoot is set to expand. First on the list of places to grow — Wasserstrum's hometown of Houston.

"Houston, in addition to being a leading market for business, is a city in transition," Wasserstrum says. "We've witnessed a growing trend of smaller companies cropping up, with startups showing that they're here to stay. I want SquareFoot to be a major part of the city's growth and evolution."

Click here to read more.

Spencer Randall, principal and co-founder of CryptoEQ

Cryptocurrency doesn't have to be a big, confusing risk with this Houston startup's technology. Courtesy of CryptoEQ

Spencer Randall got sucked into the cryptocurrency world. He found it all fascinating, and started attending — and even organizing — meetups in Houston. But he and his friends started realizing something that would turn into him co-founding CryptoEQ.

"There really wasn't a go-to resource (for cryptocurrency," Randall says on the most recent episode of the Houston Innovators Podcast. "What we wanted to do and what our mission today is to be the most trusted and intuitive analysis for cryptocurrencies."

Click here to read more.

Cryptocurrency doesn't have to be a big, confusing risk with this Houston startup's technology. Courtesy of CryptoEQ

Entrepreneur feels called to demystify cryptocurrency with his Houston startup

HOUSTON INNOVATORS PODCAST EPISODE 16

Spencer Randall, an engineer by trade, developed a fascination with cryptocurrency, and he wasn't able to shake it.

"Once I understood the technology, it wasn't really a choice. I felt compelled and driven to learn as much as I possibly could," he says on this week's episode of the Houston Innovators Podcast. "I'd say it was more of a calling."

His interest lead him to frequent cryptocurrency and blockchain meetups, and, when those started to feel all over the place, he started to host his own meetups, focused on key issues within the technology.

It was through these meetups that Randall met who would meet Brooks Vaughan, Norman Hamilton, Michael Thoma, and Joseph Romero, who would then become the co-founders of CryptoEQ.

"There really wasn't a go-to resource (for cryptocurrency," Randall says. "What we wanted to do and what our mission today is to be the most trusted and intuitive analysis for cryptocurrencies."

So, the group of entrepreneurs created CryptoEQ, which gives cryptocurrency investors a community to interact with and learn from. The company, which works out of The Cannon, launched its version 2 for the site this month and saw a 500 percent growth among users. CryptoEQ is also planning to grow its site and resources and is hiring a new full-time employee this year.

Randall discusses trends he's seen in the industry, plans for 2020, and more in the podcast episode. Listen to the full episode below — or wherever you get your podcasts — and subscribe for weekly episodes.


This week's innovators to know are all tech entrepreneurs with big ideas. Courtesy photos

3 Houston innovators to know this week

Who's who

From the science of love to confusing cryptocurrency, this week's Houston innovators to know are dabbling in some interesting industries to say the least.

Corey Allen, founder of Ecotone and treasurer of the Greater Houston LGBT Chamber

Corey Allen had entrepreneurialism in his blood — but it wasn't until he got involved with the Greater Houston LGBT Chamber that he got the courage to break out on his own. Courtesy of Corey Allen

This week's Pride Month feature is Corey Allen, who has an amazing storing into entrepreneurialism. He found confidence and encouragement from joining the LGBT chamber and started his own business. Now, he helps lead the organization as treasurer. Click here to read his Q&A with InnovationMap.

Brittany Barreto, CEO and co-founder of WeHaveChemistry

Brittany Barreto has expanded her DNA dating technology to a compatibility company named We Have Chemistry. Courtesy of WeHaveChemistry

As Brittany Barreto was working to use science to find singles love, she fielded many requests from couples who wanted in on the DNA compatibility tool she created. The requests kept coming in and now, Barreto has pivoted her dating app, Pheramor, to a new compatibility concept called WeHaveChemistry. Click here to read the full story.

Spencer Randall, principal and co-founder of CryptoEQ

Cryptocurrency doesn't have to be a big, confusing risk with this Houston startup's technology. Courtesy of CryptoEQ

Spencer Randall, through his new company CryptoEQ, wants to simplify ratings and analysis in cryptocurrency, which historically has been confusing and approachable to most. With the company's beta now live, Randall hopes that those not familiar with cryptocurrency will be able to use the platform as a learning tool. The platform takes information on trending cryptocurrency and boils it down into three columns — rating, technical analysis and trend analysis — in order for users to know when to buy or sell. Read the full story here.

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Innovative Houston research leads our top health tech news of 2025

year in review

Editor's note: As 2025 comes to a close, we're looking back at the stories that defined Houston innovation this year. The Bayou City continued to grow as a health tech hub, bringing in a multibillion-dollar pharmaceutical development, playing home based to startups developing innovative treatment options and attracting leading researchers and professionals to the city. Here are the 10 most-read Houston health tech stories of the year:

Houston Nobel Prize nominee earns latest award for public health research

Dr. Peter Hotez with Dr. Maria Elena Bottazzi. Photo courtesy of TMC

Houston vaccine scientist Dr. Peter Hotez is no stranger to impressive laurels. In 2022, he was nominated for a Nobel Peace Prize for his low-cost COVID vaccine.

His first big win of 2025 was this year’s Hill Prize, awarded by the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST). Hotez and his team were selected to receive $500,000 from Lyda Hill Philanthropies to help fund The Texas Virosphere Project, which aims to create a predictive disease atlas relating to climate disasters. Rice University researchers are collaborating with Hotez and his team on a project that combines climate science and metagenomics to access 3,000 insect genomes. The goal is to aid health departments in controlling disease and informing policy. Continue reading.

U.S. News ranks Houston hospital No. 1 in Texas for 14th year in a row

Houston Methodist is once again the top hospital in Texas. Photo via Houston Methodist

U.S. News & World Report's 2025 rankings of the best hospitals in Texas prove that Houston is in good hands.

The esteemed Houston Methodist Hospital was rated the No. 1 best hospital in Texas for the 14th consecutive year, and the No. 1 hospital in the metro area. Eleven more Houston-area hospitals earned spots among the statewide top 35. Continue reading.

Eli Lilly to build $6.5B pharmaceutical factory at Generation Park

Eli Lilly is expected to bring a $6.5 billion manufacturing facility to Houston by 2030. Rendering courtesy Greater Houston Partnership.

Pharmaceutical giant Eli Lilly and Co. plans to build a $6.5 billion manufacturing plant at Houston’s Generation Park. More than 300 locations in the U.S. competed for the factory.

The Houston site will be the first major pharmaceutical manufacturing plant in Texas, according to the Greater Houston Partnership. Lilly said it plans to hire 615 full-time workers for the 236-acre plant, including engineers, scientists and lab technicians. The company will collaborate with local colleges and universities to help build its talent pipeline. Continue reading.

How a Houston company is fighting anxiety, insomnia & Alzheimer’s through waveforms

Nexalin develops non-invasive devices that help reset networks in the brain associated with symptoms of anxiety and insomnia. Photo via Getty Images.

Houston-based Nexalin Technology is taking a medicine-free approach to target brain neurologically associated with mental illness. The company's patented, FDA-cleared frequency-based waveform targets key centers of the midbrain. Delivered via a non-invasive device, the treatment gently stimulates the hypothalamus and midbrain, helping to “reset networks associated with symptoms” of anxiety and insomnia.

Nexalin’s proprietary neurostimulation device moved forward with a clinical trial that evaluated its treatment of anxiety disorders and chronic insomnia in Brazil this year and enrolled the first patients in its clinical trial at the University of California, San Diego. Continue reading.

Houston doctor aims to revolutionize hearing aid industry with tiny implant

Houston Methodist's Dr. Ron Moses has created NanoEar, which he calls “the world’s smallest hearing aid.” Photo via Getty Images.

“What is the future of hearing aids?” That’s the question that led to a potential revolution.

Dr. Ron Moses, an ENT specialist and surgeon at Houston Methodist, is the creator of NanoEar, which he calls “the world’s smallest hearing aid.” NanoEar is an implantable device that combines the invisibility of a micro-sized tympanostomy tube with more power—and a superior hearing experience—than the best behind-the-ear hearing aid. Continue reading.

Houston scores $120M in new cancer research and prevention grants

The Cancer Prevention and Research Institute of Texas doled out 73 more grants to health care systems and companies in the state in November. Carter Smith/Courtesy of MD Anderson

The Cancer Prevention and Research Institute of Texas granted more than $120 million to Houston organizations and companies as part of 73 new awards issued statewide this fall. The funds are part of nearly $154 million approved by the CPRIT's governing board, bringing the organization's total investment in cancer prevention and research to more than $4 billion since its inception. A portion of the funding will go toward recruiting leading cancer researchers to Houston. Continue reading.

Digital Health Institute's new exec director aims to lead innovation and commercialization efforts

Pothik Chatterjee was named executive director of Rice University's and Houston Methodist's Digital Health Institute, effective May 1. Photo courtesy Rice University.

The Digital Health Institute, a joint venture between Rice University and Houston Methodist, appointed Pothik Chatterjee to the role of executive director this summer. Chatterjee’s role is to help grow the collaboration between the institutions, but the Digital Health Institute already boasts more than 20 active projects, each of which pairs Rice faculty and Houston Methodist clinicians. Once the research is in place, it’s up to Chatterjee to find commercial opportunities within the research portfolio. Those include everything from hospital-grade medical imaging wearables to the creation of digital twins for patients to help better treat them. Continue reading.

Innovation Labs @ TMC set to launch for early-stage life science startups

Innovation Labs @ TMC will open next year at the TMC Innovation Factory. Photo courtesy JLABS.

The Texas Medical Center announced its plans to launch its new Innovation Labs @ TMC in January 2026 to better support life science startups working within the innovation hub. The 34,000-square-foot space, located in the TMC Innovation Factory at 2450 Holcombe Blvd., will feature labs and life science offices and will be managed by TMC. The expansion will allow TMC to "open its doors to a wider range of life science visionaries." Continue reading.

6 Houston health tech startups making major advancements right now

Tatiana Fofanova and Dr. Desh Mohan, founders of Koda Health. Photo courtesy Koda Health.

The Health Tech Business category in our 2025 Houston Innovation Awards honored innovative startups within the health and medical technology sectors. Six forward-thinking businesses were named finalists for the 2025 award, ranging from an end-of-life care company to others developing devices and systems for heart monitoring, sleep apnea, hearing loss and more. Continue reading or see who won here.

Houston students develop cost-effective glove to treat Parkinson's symptoms

Rice University students Emmie Casey and Tomi Kuye used smartphone motors to develop a vibrotactile glove. Photo by Gustavo Raskosky/ Courtesy Rice University.

Two Rice undergraduate engineering students have developed a non-invasive vibrotactile glove that aims to alleviate the symptoms of Parkinson’s disease through therapeutic vibrations. Emmie Casey and Tomi Kuye developed the project with support from the Oshman Engineering Design Kitchen (OEDK). The team based the design on research from the Peter Tass Lab at Stanford University, which explored how randomized vibratory stimuli delivered to the fingertips could help rewire misfiring neurons in the brain—a key component of Parkinson’s disease. Continue reading.

Houston hailed as one of America's 10 best cities for startups

Startup Report

Houston's favorable economic climate is enticing new opportunities for entrepreneurship and growth, and now the city is being hailed as the 7th-best U.S. city for starting a business.

The recognition comes in CommercialCafe's recent "Best Cities for Startups" report, published December 10. The study analyzed large U.S. cities across two population categories – cities with more than 1 million residents and cities with populations between 500,000 and 1 million residents. The report analyzed relevant metrics such as office or coworking costs, Kickstarter funding success, startup density, and survival rates, among others.

Across the biggest U.S. cities with over a million residents, Phoenix, Arizona landed on top as the No. 1 best place to start a new business.

The report's findings revealed 10.6 percent of all businesses in Houston are startups that have been active for less than a year. These new businesses have a survival rate of 64.5 percent, meaning just under two-thirds of all startups in the city will still be running up to five years after they were first established.

Over the last five years, the number of new businesses established in Houston has grown nearly 15 percent. CommercialCafe said new businesses in cities with high startup growth rates tend to "attract top talent" which can eventually lead to securing "vital funding for expansion."

Independent professionals – also known as freelancers – are another crucial resource for new businesses that may need "specialized services" for a fixed amount of time, the report said. Houston's freelance workforce has grown about 9 percent from 2019-2023, and the analysis found there were 97,295 freelancers working in Houston in 2023, compared to 89,528 in 2019.

"Generally, cities in the South and Southwest have experienced strong growth during the surveyed period, in contrast to California cities like Los Angeles and San Diego, where the share of freelancers and gig workers has either stagnated or slightly declined," the report said.

Houston boasts the second-cheapest office space rent nationally, the report found. The average asking price for a 1,000-square-foot workspace (for five employees) in the city added up to $27,124 annually. For startups that want greater flexibility for their workers, the annual cost for a coworking space for the same number of employees in Houston came out to $13,200, which is the fourth-most affordable rate in the U.S.

Other Texas cities with attractive economic environments for startups

Texas, as a whole, is one of the strongest states for starting a new business. Other than Houston, San Antonio (No. 2), Dallas (No. 3), and Fort Worth (No. 4) were also recognized among the top 10 best places to start a business in the category of U.S. cities with more than a million residents.

Austin topped a separate ranking of best cities to start a business with 500,000 to 1 million residents.

"Specifically, the Texas capital was the frontrunner for indicators that looked at the overall share of startups within the local economy, as well as growth rates in five years (2019 to 2023)," the report said. "On top of that, Austin also topped the rankings for its percentage of college-educated residents and its consulting firms, which provide vital support for burgeoning enterprises."

The top 10 best cities to start a new business are:

  • No. 1 – Phoenix, Arizona
  • No. 2 – San Antonio, Texas
  • No. 3 – Dallas, Texas
  • No. 4 – Fort Worth, Texas
  • No. 5 – Jacksonville, Florida
  • No. 6 – San Diego, California
  • No. 7 – Houston, Texas
  • No. 8 – Philadelphia, Pennsylvania
  • No. 9 – Chicago, Illinois
  • No. 10 – Los Angeles, California
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This article originally appeared on CultureMap.com.

Top Houston space news of 2025 soars with NASA deals, lunar missions

Year in Review

Editor's note: As 2025 comes to a close, we're looking back at the stories that defined Houston innovation this year. The space tech sector soared with companies landing huge NASA contracts and furthering their lunar missions. Here are the 10 biggest Houston space tech stories of the year:

Houston native picked for 2025 class of NASA astronaut candidates

Houston native Anna Menon, posing below the first A in “NASA,” is one of 10 new NASA astronaut candidates. Photo courtesy NASA.

NASA has selected 10 new astronaut candidates, including one whose hometown is Houston, for its 2025 training class. The candidates will undergo nearly two years of training before they can assume flight assignments.

Intuitive Machines lands $9.8M to complete orbital transfer vehicle

Intuitive Machines expects to begin manufacturing and flight integration on its orbital transfer vehicle as soon as 2026. Photo courtesy Intuitive Machines.

Houston-based Intuitive Machines, which rang the NASDAQ opening bell July 31, secured a $9.8 million Phase Two government contract for its orbital transfer vehicle. The contract will push the project through its Critical Design Review phase, which is the final engineering milestone before manufacturing can begin.

Houston tech company tapped by NASA for near space initiative

Intuitive Machines is among four companies awarded contracts for NASA’s Near Space Network. Photo via intuitivemachines.com

In January, Intuitive Machines nailed down a NASA deal to expand the agency’s communications network for spacecraft. Additionally, NASA completed the first round of “human in the loop” testing for Intuitive Machines’ Moon RACER lunar terrain vehicle at the agency’s Johnson Space Center. RACER (Reusable Autonomous Crewed Exploration Rover) is one of three commercially developed unpressurized lunar terrain vehicles being considered for NASA’s Artemis lunar initiative.

Texas Space Commission doles out $5.8 million to Houston companies

Axiom Space and FluxWorks are the latest Houston-area companies to receive funding from the Texas Space Commission. Photo via Getty Images.

Two Houston-area companies landed more than $5.8 million in funding from the Texas Space Commission. The commission granted up to $5.5 million to Houston-based Axiom Space and up to $347,196 to Conroe-based FluxWorks in June 2025. The two-year-old commission previously awarded $95.3 million to 14 projects. A little over $34 million remains in the commission-managed Space Exploration and Aeronautics Research Fund.

Houston company awarded $2.5B NASA contract to support astronaut health and space missions

NASA has awarded KBR a five-year, $2.5 billion Human Health and Performance Contract. Photo courtesy NASA.

Houston-based technology and energy solution company KBR was awarded a $2.5 billion NASA contract to support astronaut health and reduce risks during spaceflight missions. Under the terms of the Human Health and Performance Contract 2, KBR will provide support services for several programs, including the Human Research Program, International Space Station Program, Commercial Crew Program, Artemis campaign and others. This will include ensuring crew health, safety, and performance; occupational health services and risk mitigation research for future flights.

Houston engineering firm lands $400M NASA contract

Bastion Technologies has been tapped to provide safety and mission services for NASA's Marshall Space Flight Center in Alabama. Photo via nasa.gov.

NASA granted Houston-based Bastion Technologies Inc. the Safety and Mission Assurance II (SMAS II) award with a maximum potential value of $400 million. The award stipulates that the engineering and technical services company provide safety and mission services for the agency’s Marshall Space Flight Center in Huntsville, Alabama.

Houston startups win NASA funding for space tech projects

Houston startups were recently named among the nearly 300 recipients that received a portion of $44.85 million from NASA to develop space technology. Photo via NASA/Ben Smegelsky

Three Houston startups were granted awards from NASA in July 2025 to develop new technologies for the space agency. The companies were among nearly 300 recipients that received a total agency investment of $44.85 million through the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I grant programs.

Texas Republicans are pushing to move NASA headquarters to Houston

Here's why Texas Republicans think NASA's headquarters should move to Texas in 2028. File photo.

Two federal lawmakers from Texas spearheaded a campaign to relocate NASA’s headquarters from Washington, D.C., to the Johnson Space Center in Houston’s Clear Lake area. Houston faces competition on this front, though, as lawmakers from two other states are also vying for this NASA prize. With NASA’s headquarters lease in D.C. set to end in 2028, U.S. Sen. Ted Cruz, a Texas Republican, and U.S. Rep. Brian Babin, a Republican whose congressional district includes the Johnson Space Center, wrote a letter to President Trump touting the Houston area as a prime location for NASA’s headquarters.

Intuitive Machines to acquire NASA-certified deep space navigation company

Intuitive Machines will acquire Kinetx, which marks its entry into the precision navigation and flight dynamics segment of deep space operations. Photo via Getty Images.

In August 2025, Intuitive Machines agreed to buy Tempe, Arizona-based aerospace company KinetX for an undisclosed amount. The deal is expected to close by the end of this year. KinetX specializes in deep space navigation, systems engineering, ground software and constellation mission design. It’s the only company certified by NASA for deep space navigation. KinetX’s navigation software has supported both of Intuitive Machines’ lunar missions.

Axiom Space launches semiconductor and astronaut training initiatives

Axiom Space chief astronaut Michael López-Alegría (left) trains with Axiom’s new “Project Astronaut,” Emiliano Ventura. Photo courtesy of Axiom Space.

In fall 2025, Axiom Space, a Houston-based commercial spaceflight and space infrastructure company, launched initiatives in two very different spheres — semiconductors and astronaut training.

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