This week's roundup of Houston innovators includes Angela Holmes of Mercury Data Science, Meredith Wheeler and Maggie Segrich of Sesh Coworking, and Shaun Zhang of the University of Houston. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from data science to cancer therapeutics — recently making headlines in Houston innovation.

Angela Holmes, CEO of Mercury Data Science

Angela Holmes is the CEO of MDS. Photo via mercuryds.com

A Houston-based AI solutions consultancy has made changes to its C-suite. Dan Watkins is passing on the CEO baton to Angela Holmes, who has served on MDS's board and as COO. As Holmes moves into the top leadership position, Watkins will transition to chief strategy officer and maintain his role on the board of directors.

"It is an exciting time to lead Mercury Data Science as we advance the development of innovative data science platforms at the intersection of biology, behavior, and AI," says Holmes in the release. "I am particularly excited about the demand for our Ergo insights platform for life sciences, allowing scientists to aggregate a vast set of biomedical data to better inform decisions around drug development priorities." Click here to read more.

Meredith Wheeler and Maggie Segrich, co-founders of Sesh Coworking

Sesh Coworking and its founders Maggie Segrich and Meredith Wheeler are on a roll. Photo courtesy of Sesh

Sesh Coworking, described as Houston’s first female-focused and LGBTQIA+ affirming coworking, has been operating its 2808 Caroline Street location's second-floor space since January, but the first floor, as of this week, is now open to membership and visitors. The new build-out brings the location to over 20,000 square feet of space.

Called The Parlor, the new space includes additional desks, common areas, a wellness room, and a retail pop-up space. Since its inception in early 2020, Sesh has overcome the pandemic-related obstacles in its path and even seen a 60 percent increase in membership with an overall 240 percent increase in sales over the past year.

“Our growth is a testament to the ever-changing landscape of Houston’s office and retail industry after the workplace dramatically changed in 2020,” says Maggie Segrich, co-founder of Sesh Coworking, in a news release. “We are ecstatic to welcome current and prospective members to our new, inclusive space.” Click here to read more.

The duo also joined the Houston Innovators Podcast to discuss Sesh's growth. Click here to listen.

Shaun Zhang, director of the Center for Nuclear Receptors and Cell Signaling at the University of Houston

A UH professor is fighting cancer with a newly created virus that targets the bad cells and leaves the good ones alone. Photo via UH.edu

A Houston researcher is developing a cancer treatment — called oncolytic virotherapy — that can kill cancer cells while being ineffective to surrounding cells and tissue. Basically, the virus targets the bad guys by "activating an antitumor immune response made of immune cells such as natural killer (NK) cells," according to a news release from the University of Houston.

However exciting this rising OV treatment seems, the early stage development is far from perfect. Shaun Zhang, director of the Center for Nuclear Receptors and Cell Signaling at the University of Houston, is hoping his work will help improve OV treatment and make it more effective.

“We have developed a novel strategy that not only can prevent NK cells from clearing the administered oncolytic virus, but also goes one step further by guiding them to attack tumor cells. We took an entirely different approach to create this oncolytic virotherapy by deleting a region of the gene which has been shown to activate the signaling pathway that enables the virus to replicate in normal cells,” Zhang says in the release. Click here to read more.

Sesh Coworking and its founders Maggie Segrich and Meredith Wheeler are on a roll. Photo courtesy of Sesh

With freshly opened inclusive coworking space, Houston founders look to continue momentum

houston innovators podcast episode 142

The origin story of Sesh Coworking is familiar to a lot of startups. Meredith Wheeler was looking for a new business opportunity — and the right network and work environment to do that — when she realized she didn't find anything out there that was what she needed. Then she thought — maybe building that was the next business opportunity she was looking for.

"I knew that I wanted each person who was introduced to our community felt unafraid," Wheeler says on this week's episode of the Houston Innovators Podcast. "It's really hard to walk into anywhere where anyone knows each other. I wanted it to feel to people that it was approachable."

Eventually relocating to Houston and syncing up with her now-business partner, Maggie Segrich, Wheeler started hosting pop-up coworking sessions. The meetups evolved into Sesh Coworking's small Montrose space that opened in early 2020.

This year, the duo got to have their dream of a bigger, inclusive coworking space actualized, and both phase one and two of the new Sesh Coworking space has opened in Midtown. Described as Houston’s first female-focused and LGBTQIA+ affirming coworking, Sesh's 2808 Caroline Street location provides its members with over 20,000 square feet of meeting, work, and event space.

With the bigger space, Wheeler and Segrich have the same mission of inclusivity and embracing diversity while growing its membership.

"At the end of the day, what our members really want is a feeling of belonging," Wheeler says. "They might need to get out of the house, and they might need to network a bit more. But what they want is a sense of belonging. Sesh provides that because we are this inclusive community."

Sesh, as the co-founders describe, is an attractive spot for creatives and business owners seeking a community and flexible environment. Membership is $199 a month for coworkers, and now, thanks to the expansion, Sesh also can provide private office space — even to coworker members.

"To jump into a private office — that's a big difference in pricing for some people, and that means that your business has to grow exponentially to get to that point," Segrich says. "So we try to make sure that all our members have access to private spaces for a few hours a day. We know that budgeting restraints are a big deal."

The Midtown location also has a similar opportunity for growing retail businesses. Just like the other members at Sesh, the shop gives retailers a smaller scale and less risky space compared to the costs associated with opening up their own brick-and-mortar shop.

With the challenges from the pandemic and the construction of the new store behind them, Segrich and Wheeler are already looking to the future for the company.

"First Houston — next, the world," Segrich says. "This location we've definitely set up to be the flagship, so there is definitely more Sesh coming whether that's in Houston, Texas, or somewhere else is yet to be determined.


Sesh's 20,000-square-foot space in Midtown is now completely open. Photo courtesy of Sesh

Photos: Houston coworking spot opens expanded first-floor space

where to work

A female-focused coworking space has officially opened the first floor of its Midtown Houston location after a months-long buildout.

Sesh Coworking, described as Houston’s first female-focused and LGBTQIA+ affirming coworking, has been operating its 2808 Caroline Street location's second-floor space since January, but the first floor, as of this week, is now open to membership and visitors. The new build-out brings the location to over 20,000 square feet of space.

Called The Parlor, the new space includes additional desks, common areas, a wellness room, and a retail pop-up space. Since its inception in early 2020, Sesh has overcome the pandemic-related obstacles in its path and even seen a 60 percent increase in membership with an overall 240 percent increase in sales over the past year.

“Our growth is a testament to the ever-changing landscape of Houston’s office and retail industry after the workplace dramatically changed in 2020,” says Maggie Segrich, co-founder of Sesh Coworking, in a news release. “We are ecstatic to welcome current and prospective members to our new, inclusive space.”

Sesh tapped real estate developer, The Deal Co, to work on the space and provide a catered experience for a diversified membership, including working mothers, the LGBTQIA+ community, and progressive Houstonians, per the news release.

The fully completed space now provides members with:

  • Hassle-free parking
  • 30 offices
  • Three conference rooms
  • Four phone booths
  • Amphitheater
  • Library
  • Studio kitchen
  • Pop-up retail shop for local small businesses
  • Locker rooms with showers
  • Interactive art installations
  • 24/7 access
  • Tech-enabled spaces
  • 15 percent at Weights + Measures, which directly connects to The Parlor

“Our vision is to provide a high-quality experience with a tight-knit community,” said Co-Founder Meredith Wheeler. “The Parlor’s open and collaborative atmosphere will help foster relationships, collaboration and creativity for our members.”

Photo courtesy of Sesh

This week's roundup of Houston innovators includes Dr. Toby Hamilton of Hamilton Health Box, Meredith Wheeler and Maggie Segrich of Sesh Coworking, and Simone Biles of Cerebral. Courtesy photos

4 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health to coworking — recently making headlines in Houston innovation.

Dr. Toby Hamilton, founder and CEO of Hamilton Health Box

Dr. Toby Hamilton is a leader in Houston's health care innovation ecosystem, and he joins the Houston Innovators Podcast to discuss his latest endeavor, which is rethinking primary and preventative care. Photo via tmc.edu

Dr. Toby Hamilton has seen Houston establish itself as a leader in health innovation, and he's been a part of that journey too. He started his career as a physician before founding Emerus Holdings, a micro-hospital system in the Houston area which later exited to private equity. He also founded a nonprofit focused on connecting hospital innovation leaders called the Healthcare Innovators Professional Society and led the Texas Medical Center's Biodesign program for two years.

Over the years, he says he's seen the potential develop for Houston to hold a significant role in health care innovation across the world — it's just going to take all hands on deck.

"As a community, if we can get behind that vision and be the place that tests, develops, and creates opportunities, Houston has the potential to be unlike anything in the world," he says on the Houston Innovators Podcast. Click here to listen and read more.

Meredith Wheeler and Maggie Segrich, founders of Sesh Coworking

Co-founders Maggie Segrich (right) opened Sesh with Meredith Wheeler in 2020. Photo courtesy of Sesh

One of Houston's coworking companies is moving on up. Sesh Coworking is moving into a new space that's 10 times as large as its original location — and it's an optimal location too, say Meredith Wheeler and Maggie Segrich, founders of Sesh Coworking.

"Being able to grow our community at our beautiful original location in Montrose through the pandemic is a testament to the grit and resilience of Houstonians. We are so honored and grateful to be a part of their journey,” says Segrich. “We are excited that our new location in Midtown, near the Innovation District, will provide more Houstonians with the workspace and support they need."

The two-story space is expected to open in two phases. Tenants will first move into the space's second floor in January while the first floor, the larger of the two floors, completes construction and is expected in March. Click here to read more.

Simone Biles, chief impact officer at Cerebral

Houston's favorite gymnast is the chief impact officer on a California-based tech company that's raised $462M. Photo via getcerebral.com

The greatest gymnast of all time has a new title to her many gymnastics accomplishments. Simone Biles recently joined mental health startup Cerebral as chief impact officer, and the company is backed by SoftBank and has a valuation of $4.8 billion.

Biles has been vocal about her passion for mental health. Cerebral was an official sponsor of Biles’ Gold Over America Tour, which took place from September to November, and is an official sponsor of the 2022 Simone Biles International Invitational, a gymnastics competition that will be held January 27-30 at Houston’s George R. Brown Convention Center. The Spring-based World Champions Centre, Biles’ home gym, stages the invitational.

“Mental health is just as important as physical health, but for far too long the stigma of mental health has prevented too many people from seeking help,” Biles says in a Cerebral news release. “I have my own challenges with mental health, and therapy has been very empowering for me as I try to be the best person that I can be. I believe everyone should have access to mental health resources, and Cerebral gives me the ability to personalize my mental health care experience.” Click here to read more.

Sesh Coworking's new space is 10 times as big as its previous location. Photo courtesy of Sesh

Exclusive: Houston coworking company plans to move into larger Midtown location

room to grow

A Houston startup with an inclusive approach to coworking has announced where its new location will be and plans to open in its first phase in the new year.

Sesh Coworking, which bills itself as the first female-centered and LGBTQ+-affirming coworking space, has announced its new 20,000-square-foot space at 2808 Caroline St, Suite 100 and 201. The team is all hands on deck to move over the next few weeks and formally beginning operating in the Midtown location in January 2022.

The two-story space is about ten times the size of its original location, which opened in February of 2020. Current and new tenants will move into the space's second floor in January while the first floor, the larger of the two floors, completes construction.

The new space will open in two phases. Image courtesy of Sesh

"Being able to grow our community at our beautiful original location in Montrose through the pandemic is a testament to the grit and resilience of Houstonians. We are so honored and grateful to be a part of their journey,” says Maggie Segrich, founder of Sesh Coworking. “We are excited that our new location in Midtown, near the Innovation District, will provide more Houstonians with the workspace and support they need."

The new location has hassle-free parking in a walkable part of town. In terms of layout, Sesh plans to have 25 offices, three conference rooms, four phone booths, an amphitheater, library, demo kitchen, pop-up retail shop, locker room with showers, and interactive art installations. A huge new perk of the space: 24/7 access for members.

"We plan to offer a robust calendar of programming featuring community partners such as networking events, lunch and learns, breakfast clubs, cooking classes, book clubs, business development and more," the founders tell InnovationMap.

According to Sesh, membership pricing will remain at the current rate of $199 per month, but individuals will now be able to opt into private offices starting at $789 per month for space that can accommodate teams of up to 15 people.

Sesh worked with real estate developer, The Deal Co, to customize the space in order to best meet the needs of its dynamic female and LGBTQ+ members. The new location was funded in part by a crowdfunding campaign, which raised $40,000, which represented the company’s goal. Sesh also received grant funds from the TWU Center for Women Entrepreneurs, an organization aiming to help women grow into successful business owners.

Founders Maggie Segrich (right) opened Sesh with Meredith Wheeler in 2020. Photo courtesy of Sesh

This week's roundup of Houston innovators includes Pamela Singh of CaseCTRL, Ahmad Atwan of VC Fuel, and Maggie Segrich of Sesh Coworking. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health tech to energy venture capital — recently making headlines in Houston innovation.


Pamela Singh, co-founder and CEO of CaseCTRL

Pamela Singh joins the Houston Innovators Podcast to discuss what's on the horizon for her health tech company. Photo courtesy of CaseCTRL

When COVID-19 shutdown all elective surgeries, Pamela Singh didn't know what would happen to her startup, CaseCTRL, which uses AI to optimize surgery scheduling. But, the back and forth nature of surgeries being allowed then not made for a huge need for CaseCTRL's platform to help medical facilities get back on track.

"COVID has had some sort of silver lining for us," Singh says, explaining that surgical facilities were looking for a way to catch up. "They realized the need for automating and streamlining their practice. And they realized that, instead of spending another four hours coordinating with patients and vendors, they could literally do it with the click of a button."

Singh shares more about her entrepreneurial journey and what's on the horizon for CaseCTRL, as well as her advice for fellow female founders in the podcast. Click here to read more and stream the full interview.

Ahmad Atwan, founder and CEO of VC Fuel

Ahmad Atwan founded VC Fuel in Houston to fund the future of the energy transition. Photo courtesy of VC Fuel

When Ahmad Atwan decided he was going to launch VC Fuel, a venture capital fund focused on early-stage energy transition startups, deciding where to start was easy. While there are similar funds on each of the coasts, Atwan learned that VC Fuel's concept was going to be kind of niche for Houston.

"Houston is the undisputed energy capital of the world," he tells InnovationMap. "So to me, especially when you're looking at energy transition sectors that have to work with the energy industry, it was a no brainer."

Atwan shares more about VC Fuel and the $100 million fund, which he's still raising for while also investing in a few startups at the same time, in an interview with InnovationMap. He also discusses how his expertise as a former founder and former private equity investor with Morgan Stanley and BlackRock makes him an opportune value-add investor. Click here to read more.

Maggie Segrich, co-founder and CFO of Sesh Coworking

Maggie Segrich (right) opened Sesh with Meredith Wheeler in 2020. Photo courtesy of Sesh

Maggie Segrich co-founded Sesh Coworking and the duo opened its first space in early 2020. Now, 18 months later, Sesh is growing. The female-founded, female-focused coworking company has also launched a crowdfunding campaign to support Sesh's growth.

The new coworking space is set to be in Midtown, but Sesh hasn't yet announced the specific location. The plan is to open to members at the beginning of 2022. The move will allow Sesh to offer private offices and dedicated desks, as well as other amenities members are looking for.

"Sesh never set out to be like other coworking spaces," she says. "We are on a mission to create a work space that isn't just four walls and a door. We began in 2017 by building our community first through pop-ups and then with our current space in Montrose. This new space carries on that tradition and mission of putting community first." Click here to read more.

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TMC names inaugural cohort for unique accelerator with UK

coming to HOU

Sixteen digital health and medical device startups founded in the United Kingdom have been selected for a customized accelerator at the Texas Medical Center's Innovation Factory.

In partnership with Innovate UK, TMCi created the Innovate UK Global Incubator Programme, a new accelerator that supports UK businesses as they build their United States go-to-market plan. The program builds the BioBridge relationship between TMC and the UK that was originally established five years ago.

“The TMC UK BioBridge program was launched with the UK Department for Business and Trade in 2018 to serve as a gateway for advancing life sciences and foster innovation and research between our two countries," says Ashley McPhail, chief external affairs and administration officer for TMC, in a news release. "We saw an opportunity to work with Innovate UK to develop a larger program with the UK after the success of the 11 companies that previously participated in our health tech accelerator."

The 16 companies will participate in the program from June to November. The cohort is expected to arrive in Houston on June 5 and have access to TMCi's facilities, network of mentors and potential clients, funding, potential customers, and curated programing — all while being a unique entry point into the US. The new offering joins three other globally recognized curriculums: Biodesign, Accelerator for Cancer Therapeutics, and Health Tech.

“TMCi nurtures long-term growth, development, and competitiveness to increase startups chances of success and global expansion," says Emily Reiser, associate director of TMC Innovation. "By bringing their novel technologies and exposing them to a curated selection of TMC’s expert network, startups receive support and evaluation to build, scale, and expand in the US market."

Two of the cohort's specialties include cardiovascular and oncology — two of TMC's strongest areas of expertise — with solutions ranging from surgical devices to AI-enabled risk stratification and hospital efficiency.

Innovate UK is the country's national innovation agency dedicated to supporting business-led innovation in all sectors.

“The United Kingdom is fully committed to improving global healthcare through scientific collaboration," says His Majesty’s Consul General in Texas Richard Hyde in the release. "Through the expansion of the TMC UK BioBridge and in partnership with Innovate UK, this programme will help to expose the brightest and best British companies to the world’s largest medical city. Our companies will collaborate and grow as they work to develop cutting edge technology. The partnership between the UK Government and TMC demonstrates that international collaboration can drive both economic growth and improvement to quality of life.”

The 16 companies making up the inaugural cohort are as follows, according to TMC.

  • AINOSTICS aims to revolutionize the treatment and prevention of neurological conditions, such as dementia, by developing innovative AI-enabled solutions that draw novel insights from routinely acquired non-invasive medical scans to deliver accurate diagnosis and outcome prediction, and in turn facilitate personalized care and timely access to disease-modifying treatments for patients.
  • Alvie is a blended human plus AI-enabled digital solution providing personalised pre and rehabilitation coaching and supportive care for cancer and surgery. Alvie's technology combines data profiling, risk-stratification and tailored prescriptions of health and well-being with curated educational content, targeted behaviour change coaching and expert support through chat messaging and virtual consultations.
  • C the Signs™ is a validated AI cancer prediction platform, which can identify patients at risk of cancer at the earliest and most curable stage of the disease. Used by healthcare professionals, C the Signs can identify which tumor type a patient is at risk of and recommend the most appropriate next step in less than 30 seconds. The platform has detected over 10,000 patients with cancer, with over 50 different types of cancer diagnosed, and with a sensitivity of >98% for cancer.
  • At PEP Health, We believe all patients deserve the best care possible. Our cutting-edge machine-learning technology enables healthcare organisations, regulators, and insurers the real-time, actionable insights they need to have a direct and dramatic impact on patient experiences.
  • PreciousMD improves the lives of lung-cancer and other lung-related illnesses patients worldwide by enabling imaging-based diagnostics needed for personalized treatment pathways.
  • Ufonia is an autonomous telemedicine company, we use large language models and voice AI to increase the capacity of clinical professionals.
  • My mhealth offers digital therapeutics for a range of long-term conditions- COPD, Asthma, Diabetes and Heart Disease. Our product has been successfully deployed in the UK and India, with >100,000 users registered to date. Our solutions empower patients to self-manage their conditions, resulting in dramatic improvements in outcomes, as evidenced through multiple clinical trials and real-world evaluations.
  • At Surgery Hero, we offer a clinically backed solution that ensures whole-human support before and after surgery. We help health systems, employers and health plans cut costs without sacrificing quality of care.
  • Panakeia's software platform enables extremely rapid multi-omics profiling in minutes directly from routinely used tissue images without needing wet lab assays.
  • QV Bioelectronics are striving to deliver longer, better quality lives for brain tumour patients. Using their first-of-its-kind implantable electric field therapy device, GRACE, QV will provide effective, focal & continuous treatment without impacting patient quality of life.
  • 52 North is a med-tech company focused on improving health outcomes and health equity by reinventing care pathways. The NeutroCheck® solution is a finger-prick blood test and digital platform built to significantly improve safety and quality of life for cancer patients, by helping to identify at-home those patients who are at risk of the most fatal side-effect of chemotherapy: neutropenic sepsis.
  • Somnus is fulfilling an unmet need in global healthcare by developing real-time, point of care blood propofol monitoring. Its products will improve the care of sedated and anaesthetised patients, save money for hospitals, and facilitate a major reduction in greenhouse gas emissions.
  • ScubaTx is a breakthrough organ transplant preservation company established to solve the global unmet need for cost-efficient and longer-duration organ preservation technology. ScubaTx has developed a simple, small and affordable device which uses Persufflation to extend the preservation of organs.
  • IBEX is on a mission to help people live active, healthy and productive lives by increasing their access to early diagnosis of osteoporosis. The IBEX BH software as medical device delvers routine, automated assessment of fracture risk from routine radiology for earlier detection and more equitable treatment of osteoporosis.
  • NuVision produces products derived from donated human amniotic membrane that are used in ophthalmology to help patients with chronic, traumatic and post-surgical wounds of the eye to be treated earlier and recover more fully and more quickly. The company’s products are also used in the management of dry eye disease, a debilitating conditions that affects around 17m people in the USA.
  • Calon Cardio-Technology is on a mission to improve quality of life for patients with Left Ventricular Assist devices (LVAD) and reduce the common post operative complications associated with these implantable heart pumps. We plan to do this by introducing a completely wireless heart pump system and augment patient follow-up with built-in remote monitoring capabilities.

UH lab using mixed reality to optimize designs for the Moon and Mars

hi, tech

University of Houston researchers and students are bringing multiple realities together to help improve the design process for crewed space missions.

Helmed by Vittorio Netti, a researcher for UH and a space architect, the university has launched an XR Lab within the University of Houston architecture building. The lab allows researchers to combine mixed reality (MR), virtual reality (VR), augmented reality (AR) and extended reality (XR) to "blend the physical and digital worlds" to give designers a better understanding of life in space, according to a release from UH.

In the lab researchers can wear MY space suits and goggles, take a VR space walk, or feel what it's like to float to the International Space Station with the help of XR and a crane.

The area in which the researchers conduct this work is known as the "cage" and was developed during a six-month research and design study of lunar surface architecture sponsored by Boeing, which aimed to learn more about the design of a lunar terrain vehicle and a small lunar habitat.

The work is part of UH's Sasakawa International Center of Space Architecture (SICSA), which is led by Olga Bannova, a research associate professor and director of the space architecture graduate program at UH.

She says work like this will drastically cut down research and development time when designing space structures.

“These technologies should be harnessed to mitigate the dependency on physical prototyping of assets and help optimize the design process, drastically reducing research-and-development time and providing a higher level of immersion,” Bannova said in a statement.

Today the research team is shifting its focus on designing for a Mars landing. In the future, they aim to demonstrate and test the system for habitats designed for both lunar and Martian surfaces. They are also working with Boeing to test designs in microgravity, or zero gravity, which exists inside the International Space Station.

Mixed Reality Raising the Bar for Space Architecture on the Moon and MarsStep into this 'Cage' at the University of Houston where physical and digital worlds are merged, allowing students to see and ...