Houston Exponential leader resigns, interim named

leadership change

Harvin Moore has resigned from his position as president of Houston Exponential. Serafina Lalany is acting as interim executive director. Photos courtesy of HX

Houston Exponential has announced a leadership change, according to a statement from the organization.

Harvin Moore, who has served as president of HX since June 2019, has announced his resignation to the chair of the organization, Barbara Burger, vice president of innovation at Chevron and president of Chevron Technology Ventures. In the statement, Burger says Moore is resigning to devote more time to working with growth-stage companies as a mentor, adviser, and investor.

Serafina Lalany, vice president of operations at HX, will act as interim executive director.

"In a rapidly growing and evolving landscape like this one, we must ensure resources are leveraged for greatest impact," Burger says. "The HX executive committee believes now is an appropriate time re-strategize with the HX organization to ensure it is aligned with the current needs of the innovation ecosystem. While changes may be called for to place resources where they can do the most good, there remains a need for a broad ecosystem champion and HX will continue to serve in that role."

Moore — who followed Russ Capper, the inaugural executive director of HX — has a 20-year career in tech and startups in Houston. He is a principal at an early-stage investment firm, Frontera Technology Ventures, and before that served as COO for Space Services Holdings Inc. According to his LinkedIn profile, he's also the director of Industrial Tech Acquisitions Inc., a blank check company, or SPAC.

"Under Harvin's leadership over the last two years, HX has maintained its successful trajectory and achieved important milestones," Burger continues in the statement. "I wish him well in his future endeavors."

According to the statement, all other Houston Exponential staff will remain in place during this review period to support ongoing activities.

Houston's VC activity has hit a new milestone. Photo via Getty Images

Report: Houston venture capital raised exceeds $1B over the past year

VC update

Over the past 12 months, companies in Houston have raised over $1 billion in venture funding — for the first time, according to a new report from Houston Exponential.

"Crossing the billion-dollar mark is a watershed moment for Houston," says Harvin Moore, president of Houston Exponential, in the report. "Venture capital invested in Houston startups has tripled since 2016."

HX was founded in 2017 to focus on convening citywide efforts towards growing Houston's technology innovation ecosystem.

"The sustained level of progress we've seen in startup formation and growth over the past four years shows that Houston has what it takes to do what other leading cities have done: build a vibrant and healthy innovation economy," Moore continues.

Source: Pitchbook and Houston Exponential

Reaching this new benchmark is due to an active first quarter of 2021. VC funding from January through April 2021 totaled $748 million across 53 deals. This figure represents more VC funding than all of 2020.

Some of the year's largest VC deals so far include:

The industry breakdown has evolved as well, according to the report. Information technology represents the largest chunk of the $1.1 billion raised in Houston between April 2020 and April 2021, followed closely by health care.

Source: Pitchbook and Houston Exponential

There's still progress to be made, according to Moore, but these numbers represent significant growth of the ecosystem.

"We've come a long way in a short time, but it's still very early in the game," says Moore in the release. "Our rate of startup formation and growth is still much smaller than other cities, including some significantly smaller than Houston. But these results are making it more clear than ever that Houston is a great place to start and grow a business – and I think we will see these numbers continue to grow."

According to a new report, Houston's energy and health care industries are attracting the most VC investment — with cleantech and oncology investments specifically on the rise. Graphic via the Houston Tech Report by the GHP

New report shows what industries in Houston are attracting the most venture capital investment

following the money

According to a recently released report, a few key industries in Houston have attracted the bulk of the city's venture capital investment dollars.

The Houston Tech Report by the Greater Houston Partnership and Houston Exponential has revealed that the city is home to 8,800 tech-related firms, including over 700 venture-backed startups that have attracted over $2.6 billion in VC funding over the past five years. Annual VC investment has tripled in that same timeframe — from $284 million in 2016 to $753 million in 2020.

"Houston is a city that has been leading the way for decades, with breakthrough innovations that have truly changed the world," says Bob Harvey, president and CEO of the Greater Houston Partnership, in a news release. "Over the past few years, we have been working to transform an already incredible economy into one that competes as a leading digital tech city."

Zooming into the industries attracting the most capital in Houston, life sciences and oil and gas technology continue to reign supreme. Of the VC dollars going into Houston companies, 17 percent goes into life science companies and 17 percent goes into oil and gas, according to the report. Cleantech and Oncology are both niches in Houston that have seen growth in VC investment.

Graphic via the Houston Tech Report by the GHP

Software as a service has seen significant growth since 2011, and represents the third-most invested in industry with 14 percent of the VC investment.

Contributing to the innovation ecosystem's growth is an increase in startup development organizations — the city now has added over 30 SDOs including non-profits, incubators/accelerators, coworking spaces and makerspaces since 2017 — and access to tech talent. According to the report, Houston has the 12th largest tech sector in the U.S. with 235,000 tech workers, and this sector generates $28.1 billion to the region's GDP.

"Houston in 2020 had not one but two unicorns (private tech companies exceeding a $1 billion valuation), our first ever," says Harvin Moore, president of HX. "That's a reflection of both the rate of growth and early stage of our ecosystem. We will see an increasing number of startups as these companies continue to grow and others follow."

Graphic via the Houston Tech Report by the GHP

According to the report, the most active investors into Houston-based companies between 2017 and 2020 include Austin-based Capital Factory with 29 deals, Houston-based TMC Innovation with 25 deals, and Houston Angel Network with 23 deals.

Houston Exponential's Harvin Moore and Serafina Lalany join this week's Houston Innovators Podcast to discuss The Listies. Photos courtesy

New awards to 'pay homage' to Houston's tech scene

HOUSTON INNOVATORS PODCAST EPISODE 55

The deadline for nominations has been extended to November 6. The original story below has been edited to reflect the extension.

With so much of 2020 going wrong, a new awards program is hoping to shine a spotlight on Houston tech startups and other major innovation players who are doing things right.

The Listies nominations are open online until this Friday, November 6, and are being hosted by Houston Exponential in partnership with InnovationMap.

"The idea for The Listies has been in the back of our minds for a long time," says Serafina Lalany, chief of staff at HX, on this week's episode of the Houston Innovators Podcast. "There has always been a need in the ecosystem to celebrate the wins and vibrant culture we have here. This is an opportunity to pay homage to that."

The 12 awards will recognize growing startups, individuals, mentors, corporations, investors, and more. Award eligibility requires nominees to have an account on HX's new platform, the HTX TechList, which is free to use and is intended to be a virtual meeting place and resource for Houston innovation.

The honorees will be awarded at a virtual event ceremony at 3 pm on Friday, November 30. The event is hoping to duplicate the engagement the organization saw at its HTX TechList launch in August, which had over 1,000 registrants and a message from Mayor Sylvester Turner.

"This ecosystem really eats up events — even if they are virtual," says Harvin Moore, president of HX, on the podcast. "This will be another opportunity for the organizations and all the people in the ecosystem to get together. ... It's also an opportunity to continue to develop what's happening in Houston."

The event is gathering tech and innovation influencers to promote and play a role in the event — from judges to award presenters. The program is also seeking sponsors to be included in the event as well.

"HX's true strength is bringing people together around a common mission, and this is very true to that," Lalany says.

Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


Houston Exponential has a released a report that found that Houston tech companies have seen a 7 percent year-over-year increase in venture capital investments so far in 2020. Getty Images

Houston tech companies have raised over $466M so far this year, new report finds

money moves

This year might be a wash for a lot of things, but according to a new fundraising report from Houston Exponential, the Bayou City has seen an increase in funding this year compared to 2019.

The HTX Funding Review found that Houston startups raised $466.33 million across 46 deals between January and July — compared to $437 in the same time frame last year. While the increase seems marginal, it's important to consider the effect of the pandemic and the few months of troubles for the oil and gas industry.

The 7 percent increase in funding is impressive compared to the national average of 2.5 percent, according to the report, which was organized by Serafina Lalany, HX chief of staff. Eighteen later stage deals made up for 76 percent of the total money raised, indicating key growth for the ecosystem.

"This expansion in Houston's relatively new and booming tech innovation ecosystem shows a strength and resilience that is really exciting," says Harvin Moore, president of HX, in the report. "We are seeing a maturation of our very young ecosystem, as rapidly growing tech companies increasingly access later stage venture capital, which often comes from outside the local area."

The report calls out 11 deals — ranging from angel to late stage — that have occured in Houston to date in 2020:

  • Preventice Solutions, a medical device company, raised a $137 million series B led by Palo Alto-based Vivo Capital along with support from existing investors, including Merck Global Health Innovation Fund, Boston Scientific, and the Samsung Catalyst Fund.
  • Fintech and software-as-a-service company HighRadius raised a $125 million series B led by ICONIQ Capital, with participation from existing investors Susquehanna Growth Equity and Citi Ventures.
  • Liongard, a SaaS company, raised a $17 million series B led by TDF Ventures, Integr8d Capital, and private investors.
  • Base Hologram, a provider of hologram concert experience, raised $15.4 million in an outsized angel round this past May.
  • ThoughtTrace, another SaaS company, raised $10 million in a series B led by McRock Capital and existing investors, as well as Chevron Technology Ventures.
  • Renewable energy company Quidnet also raised a $10 million series B. Bill Gates-backed Breakthrough Energy Ventures and Canada-based Evok Innovations, which both previously invested in the company, contributed to the round.
  • SmartAC.com emerged from stealth mode witha $10 million series A fundraising announcement.
  • Retina AI, an AI company focused on diagnostics for diseases such as diabetic retinopathy from pictures of the retina, raised $4.1 million in an angel round which closed mid-July.
  • E-commerce platform Goodfair raised $3.67 million from but the round was led by Imaginary, with support from MaC Venture Capital, Global Founders Capital, Willow Ventures, Watertower, Amplify.LA, Capital Factory, and Texas Ventures.
  • SecurityGate, a cybersecurity platform, raised funds from Houston Ventures in June, but wouldn't disclose how much.
  • Oil and gas software company, M1neral, raised $1.6 million pre-seed co-led by Amnis Ventures and Pheasant Energy, among a few other select investors and strategic partners.

While the pandemic has made funding and vetting new portfolio companies, Blair Garrou, managing director of Houston-based Mercury Fund, says venture capital firms are committed to backing the strongest startups already in their portfolio.

"We've seen many VCs focus on a 'flight to quality,'" Garrou says. "Specifically, VCs are focused more on making sure their best performing portfolio companies have cash, especially at the later stages, as well as investing in the later rounds of new deals that are clear over-performers during COVID."

Looking forward, the HX report predicts that fundraising growth will continue throughout the rest of the year.

"There are several very large local deals in final term sheet stage, and we expect full year 2020 to be the highest ever for venture capital in Houston; our ecosystem is really thriving," says Moore in the report.

According to a survey from Houston Exponential, the Bayou City's startup founders see the light at the end of the pandemic's dark tunnel. Photo by Zview/Getty Images

Houston founders optimistic about COVID-19 recovery, survey finds

thinking positive

Given the current economic environment, you might think founders of Houston startups would view the future with a healthy dose of pessimism. But you'd be wrong.

A survey conducted between April 23 and May 7 by Houston Exponential, a nonprofit that promotes the local innovation ecosystem, revealed that Houston startup founders largely see the future through a lens of optimism. For example:

  • More than half of the startups that said they were harmed by the coronavirus pandemic believe they'll begin bouncing back before the end of this year.
  • 70 percent of the startups that said they were hurt by the pandemic believe they'll begin recovering before they run out of cash. "They're saying, 'We're making it through this to the other side, and we're going to be better on the other side," says Bryant Chan, director of product at HX.
  • 80 percent of startups said they planned to add employees within the following 12 months.
  • Two-thirds of startups said they had a funding runway of at least six months.

"Houston is a resilient city, and its agile founders are the most adept at making the best of any situation," HX states in a summary of the survey results.

HX sent the survey to more than 1,000 startup founders in Houston. The survey results include responses from founders of companies with 30 or fewer employees.

Harvin Moore, president of HX, says he wasn't surprised by the generally optimistic outlook of Houston startup founders. In part, that's because local startups as a whole aren't swimming in deep pools of venture capital, according to Moore. Lower valuations lead to lower overhead and shorter cash runways, translating into abundant resilience, he says.

Moore suspects that if a startup founders survey were to be conducted in a VC hotbed like Silicon Valley, "we would probably find less resilience just because there were higher burn rates and, therefore, more dependence on runway."

Chan says startups in Houston hold an advantage over startups in hotspots like Silicon Valley because they're used to practicing "capital efficiency."

"Hopefully, we will maintain that as an advantage," Moore says.

Despite the optimistic elements of the survey results, Houston startups are encountering obstacles. Those include:

  • One-third of startups with at least six employees said they carried out layoffs or furloughs as a result of the pandemic-scarred economy.
  • Thirty percent of startups said they saw contracts fade and revenue shrink because of the pandemic.
  • Nearly one-fifth of startups that said they were raising capital before and during the pandemic saw their valuations decline by 10 percent to 20 percent.

One of the most noteworthy findings in the negative column was that the No. 1 hiring challenge for startups (cited by 21 percent of them) was offering competitive pay.

"Founders are finding talented candidates in Houston, but are unable to meet their salary demands," HX states. "It's common for startups to compensate early employees through company equity in lieu of salary, but with such economic uncertainty, employees may prefer that guaranteed cash and liquidity."

Before the pandemic, the top hiring challenge for Houston startups likely would have been finding the right talent, Chan says.

Despite such challenges, the path ahead for Houston's startup community seems to be pretty smooth, particularly as organizations like HX keep pursuing more access to angel, early stage, and seed funding.

"We have a strong economy, low cost of living — all these things that are solid about Houston and are not going away," Moore says. "We're confident that 2021 will be a great year. 2020 is probably going to be — for most people in Houston, just like around the rest of the country — the year of reimagining and repositioning and recovering. For some companies, it's going to be a huge inflection-point year."

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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

money moves

Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

Top Houston startups, innovators win big, space tech rolls out rover, and more trending news

top stories

Editor's note:Let's roundup the most-read Houston innovation news from the week. Trending Houston tech and startup articles from InnovationMap and its daily newsletter included the announcement of the Houston Innovation Awards winners, Intuitive Machines rolling out its rover, and more.

2024 Houston Innovation Awards winners named at annual event

This year's award recipients span industries and technologies. Photos courtesy

Houston innovators — the moment you've been waiting for. The winners of the 2024 Houston Innovation Awards were named at the annual event.

The Houston Innovation Awards honored over 40 finalists across categories, naming the 12 winners and honoring the two Trailblazer Legacy Awards at the event. Click here to see the winners.

Photos: Houston Innovation Awards celebrates city's startup, tech leaders at annual event

Over 500 members of Houston's innovation community showed up to celebrate the best and brightest of the ecosystem. Photo by Emily Jaschke/InnovationMap

The 2024 Houston Innovation Awards season has come to a close with last week's event.

With a crowd of around 500 attendees, the Houston Innovation Awards, which took place on November 14, celebrated over 40 finalists and a dozen winners across categories. Click here to view photos from the event.

Houston space tech co. rolls out futuristic lunar rover for NASA's Artemis missions

Intuitive Machine unveiled its RACER lunar terrain vehicle at Space Center Houston. Photo courtesy of Intuitive Machines

Houston-based space exploration company Intuitive Machines just unveiled its version of a lunar terrain vehicle that’s designed to be used by astronauts in NASA’s Artemis moon discovery program.

Intuitive Machine recently rolled out its RACER lunar terrain vehicle (LTV) at Space Center Houston. RACER stands for Reusable Autonomous Crewed Exploration Rover. Click here to continue reading.

Houston accelerator names inaugural cohort to propel digital transformation in energy

The NOV Supernova Accelerator will work to cultivate relationships between startups and NOV. Photo via Getty Images

Houston-based Venture Builder VC has kicked off its NOV Supernova Accelerator and named its inaugural cohort.

The program, originally announced earlier this year, focuses on accelerating digital transformation solutions for NOV Inc.'s operations in the upstream oil and gas industry. It will support high-potential startups in driving digital transformation within the energy sector, specifically upstream oil and gas, and last five months and culminate in a demo day where founders will present solutions to industry leaders, potential investors, NOV executives, and other stakeholders. Click here to continue reading.

2 Houston health innovation leaders award grants to cancer-fighting researchers

The Cancer Bioengineering Collaborative announced the projects that were selected for its first round of seed grants. Photo via Rice.edu

Five cancer-fighting research projects were named inaugural recipients of a new grant program founded by two Houston institutions.

Last summer, Rice University and The University of Texas MD Anderson Cancer Center announced they were teaming up to form the new Cancer Bioengineering Collaborative. The shared initiative, created to form innovative technologies and bioengineering approaches to improve cancer research, diagnosis and treatment, recently launched with an event at the TMC3 Collaborative Building in Helix Park. Click here to continue reading.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.

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