Overheard: Houston's innovation leaders weigh in on the city's developing ecosystem at SXSW

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The city's top power players within Houston's energy innovation ecosystem joined virtual SXSW to discuss Houston's life science innovation scene and developing an inclusive ecosystem. Photos courtesy

Another day of SXSW 2021 has concluded, and just like the first day, Houston innovators logged on to discuss technology and innovation that's taking off in town.

The second of the two days of programming focused on the development of the Houston innovation ecosystem — including how the city is factoring in diversity and inclusion into development — with interviews hosted by me, Natalie Harms, editor of InnovationMap. Missed out on the fun? Catch up with a few overheard moments from Houston House or stream the full interviews below.

"“We have to be true to ourselves of what works for Houston. Making sure the DEI is interwoven and in our DNA of our ecosystem so that we don’t make the same mistakes as other cities." — Ashley DeWalt, managing director of DivInc Houston

Video courtesy of the Greater Houston Partnership

Houston has an advantage in developing its innovation ecosystem because it can do so by learning from established ecosystems on the coasts. Locally, that means making diversity and inclusion a top priority. At a virtual SXSW Houston House panel, Ashley DeWalt, managing director of DivInc Houston, and Jan Odegard, interim executive director of The Ion, discuss the importance of prioritizing inclusion in developing Houston's innovation ecosystem. Click here to watch the full interview.

“This pandemic has really highlighted a lot of the health care disparities that are present within our systems. … Houston is in a unique position to address that.” — Fiona Mack, head of JLABS @ TMC

Video courtesy of the Greater Houston Partnership

The Texas Medical Center is the largest medical center in the world with over 10 million patients coming in annually — and JLABS @ TMC is right in the middle of that. With this access to patients and clinical trials, Houston has a lot of potential to attract new innovative companies solving the world's biggest health care problems. At a virtual SXSW Houston House HOU Talk, Fiona Mack, head of JLABS @TMC, discusses the momentum behind health tech innovation in Houston. Click here to watch the full interview.

“Whatever the training is, you have to actually create bias disruptors and points of friction and processes that change behavior. If we don’t have a way to implement what we learn, it doesn’t really change culture.” — LaTanya Flix, senior vice president at the GHP

Video courtesy of the Greater Houston Partnership

In light of the Black Lives Matter movement, corporations of all shapes and sizes were inspired to look inward to address inequity within their workforce — from training to shifts in workplace culture. At a virtual SXSW Houston House HOU Talk, LaTanya Flix, senior vice president of Diversity, Equity and Inclusion (DEI) at the Greater Houston Partnership, shares how she's on a mission to spread mindful DEI initiatives across all of the GHP's member organizations. Click here to watch the full interview.

“I see a world where I’m sitting in a boardroom, and I’m not the only woman anymore.” — Samantha Lewis, principal at Mercury Fund

Video courtesy of the Greater Houston Partnership

Women in venture capital are used to being the only women in the room and are fighting for that not to be the case for future generations. At a virtual SXSW Houston House panel, Sandy Guitar, managing director of the HX Venture Fund moderates a discussion with fellow women in VC, Paige Pitcher, director of innovation at Hines, and Samantha Lewis, principal at Mercury Fund. Click here to watch the full interview.

“There’s an incredible number of innovations that have popped up in Houston, but a lot of them have been centered around solving engineering-type problems at industrial scale — and that still exists, but doesn’t get as much coverage as consumer-facing technologies.” — Josh Pherigo, director of research and data analytics at GHP

Video courtesy of the Greater Houston Partnership

When tracking any sort of progress or growth, business look to their numbers and data. Houston's innovation system is no different. At a virtual SXSW Houston House HOU Talk, Josh Pherigo, director of research and data analytics at the Greater Houston Partnership, dives in deep with the facts and figures of Houston's burgeoning innovation ecosystem by following the venture dollars coming into local startups. Click here to watch the full interview.

“If you look at the density in Houston, being the energy capital of the United States, there are probably few places in the world where you can walk 15 minutes in either direction and talk to about 100 companies that would potentially be customers.” — Matthew Costello, CEO and co-founder of Voyager Portal

Video courtesy of the Greater Houston Partnership

A good startup idea comes from necessity and a way to apply technology to solve problems and shorten business delivery times, and the maritime shipping industry has a lot of opportunities for these types of innovations. At a virtual SXSW Houston House HOU Talk, Matthew Costello, CEO and co-founder of Voyager Portal, sets sail on a conversation about the maritime shipping industry — and how it was ripe with disruption. Click here to watch the full interview.

“You have institutions of exception in Houston where innovation flows from. The question isn’t that it’s not there, it’s how have we been tapping it.” — David Schubert, president of Magnolia Tejas Corp.

Video courtesy of the Greater Houston Partnership

Houston has a burgeoning life science innovation scene — but what's that next step for its development? At a virtual SXSW Houston House HOU Talk, David Schubert, president of Magnolia Tejas Corp. discusses the potential of Houston's world-class oncologists and biotech innovators have to make the city a hub for cancer innovation. Click here to watch the full interview.

The ultimate who's who of 2020 — favorite Houston Innovators Podcast guests of last year. Photos courtesy

Editor's Picks: Top 7 Houston innovation interviews of 2020

2020 in review

Editor's note: With 2020 in the rearview, InnovationMap is looking back on the top stories of the year. With over 60 episodes of the Houston Innovators Podcast and about half of those being recorded in 2020, here are the top episides from the year.

Chris Buckner, co-founder and CEO of Mainline

With sports went offline, esports startup Mainline saw an opportunity for growth during the COVID-19 outbreak. Photo courtesy of Mainline

What happened when collegiate sport stadiums shut down and seasons were postponed? People started to turn to esports to get their competitive fix. And Houston-based esports tournament software company Mainline saw a huge boost to business.

"Everyone is looking for how to get sports, or esports, in front of people because everyone is just missing [sports] so much," Chris Buckner, co-founder and CEO of Mainline, says in a June episode of the Houston Innovators Podcast. "We've been very fortunate to work in the industry we do."

On campuses this past spring, colleges are looking for a way to connect with and engage students, Buckner says. And, Mainline has even been able to attract interest on the professional level.

"Our June will pretty much be the best month of our company, and a lot of that is driven by the fact that everyone is looking for a digital solution rather than an in-person solution," Buckner says.

Read more and stream the podcast episode here.

Fiona Mack, head of JLABS @ TMC

Fiona Mack joined JLABS @ TMC as head of the incubator. Photo courtesy of JLABS

Last year, JLABS @ TMC — a local health tech startup incubator under the Johnson & Johnson arm — welcomed Fiona Mack as the new head of the program. On her plate was assessing the needs of the incubator's 49 member companies in the portfolio and understanding the needs of the Texas innovation ecosystem.

"As I learn more about the history of life science sector in Texas, over the past 20 years there has been an impetuous to build up this critical mass of companies here to really make it a strong hub that competes with the energy sector to make it a pillar of the economy here," Mack says in a November episode of the Houston Innovators Podcast.

One of the things that's top of mind for Mack is a focus on diversity — both from an entrepreneurship and a representation standpoint.

"From a research perspective, there's a strong effect of having a lack of diversity in a lot of the metrics we're looking at," she shares.

Read more and stream the podcast episode here.

Joe Alapat, CEO of Liongard

Joe Alapat is the CEO of Houston-based Liongard, which just raised a $17 million series B round. Courtesy of Liongard

Despite a pandemic that at least in some ways negatively affected venture capital investment, a Houston software startup managed to persevere with a $17 million series B. Liongard's CEO Joe Alapat, who co-founded the company with COO Vincent Tran in 2015, says in a May episode of the Houston Innovators Podcast that the round was the result of ongoing relationships with advisers and investors that meant a successful round — even in light of a pandemic.

In the episode, Alapat also shares his advice for Houston startups looking to tap into the Houston innovation ecosystem — something he's watched grow over the past five years. Now, he says, when it comes to new startups in Houston, "the waves are hitting the shore."

"Houston has always been an entrepreneurial city, and this is just that next stage," Alapat says on the episode. "For me, it's the technology side that excites me even more to see technology companies really succeeding."

Read more and stream the podcast episode here.

Megan Eddings and Amanda Cotler of Accel Lifestyle

Megan Eddings and Amanda Cotler of Accel Lifestyle joined the Houston Innovators Podcast to share how they made the pivot from making T-shirts to face masks. Photos courtesy

For years, Megan Eddings, founder and CEO of Accel Lifestyle, worked on perfecting the perfect antibacterial fabric for an anti-stink athletic clothing line, but it only took her a few weeks to pivot toward using the material to make masks.

On a May episode of the Houston Innovators Podcast, Eddings and Amanda Cotler, director of operations, shared the story of how this pivot came to be and how they saw the Center for Disease Control was recommending wearing bandanas and cloth when face masks weren't available, they had an epiphany.

"Megan and I read that and immediately hopped on a call with our team," Cotler says. "We had a realization with our antibacterial fabric that a face mask made from it would be so much cleaner."

Within 24 hours, the duo had a sample in their hands, and they had 14,000 yards of their Prema fabric being shipped from California to Houston, where they had managed to find 60 local sewers ready to start making the masks.

Now, with the Houston workforce making moves to return to the workplace, Eddings says she's seen an increased interest in corporations wanting custom masks with the company logo on it for their employees.

Read more and stream the podcast episode here.

Durg Kumar and Allen Bryant, partners at Knightsgate Ventures

Houston-founded venture capital firm heads into second fund focused on social impactDurg Kumar (left) and Allen Bryant, partners at Knightsgate Ventures, join the Houston Innovators Podcast to discuss their second fund. Photos courtesy

Durg Kumar founded Knightsgate Ventures in order to find and fund startups with a social impact and a profitable business strategy. The Houston-based firm was founded in Houston and has since expanded to add a New York partner, Allen Bryant, to the operation. The duo joined the Houston Innovators Podcast in November.

"For a very long time, there was a perceived trade off between social returns and financial returns," Bryant says on this week's episode of the Houston Innovators Podcast. "What we are seeing now is that's really not the case. You actually have businesses that are bringing impactful change and those businesses are propelled by that."

The VC's first fund invested in six startups — including Houston-based Voyager — and is now heading into its second fund. Kumar says the first fund's success was in part due to his network. Now heading into the second go around, Knightsgate's network has grown with the addition of Bryant.

The end of the year, Kumar and Bryant were focused on helping their portfolio startups focus on the next year.

"Now's a good time to retrench and focus on building product," Kumar says, "so that in 2021 when travel restrictions ease, then you've got your refined product to go out and take it to the customers."

Read more and stream the podcast episode here.

Joy M. Hutton, local leader of the Grow with Google in Houston

Joy M. Hutton leads the Grow with Google in Houston. Photo courtesy of Google

In November, when Google announced it was expanding its Grow with Google Digital Coach program to Houston, Joy M. Hutton was named the local leader. The entrepreneur and business consultant is hoping to help provide important business resources to entrepreneurs just like herself.

"In Houston, you have a lot of different resources that weren't available to startups before just within the past few years, and I think that's huge," Hutton says in a December episode of the Houston Innovators Podcast. "Being more inclusive with people who need the resources who haven't traditionally had access to those resources is a big initiative. I personally am proud to be a part of that."

Hutton specifically calls out resources like MassChallenge and Founder's Institute — both of which she serves as a mentor for — as well as DivInc, gBeta, and of course the Grow with Google program. To get involved, Houston entrepreneurs can head online to learn more and keep an eye out for monthly classes online — and hopefully, in the future, in person events as well.

Read more and stream the podcast episode here.

Kyle Judah, executive director of Rice University's Liu Idea Lab for Innovation and Entrepreneurship

Kyle Judah joins the Houston Innovators Podcast to discuss his new role. Photo courtesy of Lilie

When Kyle Judah accepted his position as executive director at Rice University's Liu Idea Lab for Innovation & Entrepreneurship, he had spent less than 48 hours in the city of Houston. In fact, his first two months in the role have been spent completely remote and out of town.

Still, his limited in-person interaction with the city and with Rice made an impact.

"One of the things I found so exciting about what's going on in Houston right now that, quite frankly, was incredibly attractive about the opportunity to come and join Lilie and Rice was that Houston has these big pillar companies in energy and health care and all these critical areas that the world, the economy, and the society needs," Judah says in a September episode of the Houston Innovators Podcast. "That's all in Houston right now."

Judah and Lilie's goal is to help identify the innovation happening on campus at Rice and bring it to the world. And, he says, Rice as a whole has a huge place in the greater Houston innovation ecosystem. The challenge is identifying what industries Houston and Rice have an opportunity to disrupt.

"We can't just copy and paste what works for the Bay Area or what works for Boston," he says. "We have to figure out what is going to be the authentic right sort of centers of excellence for Rice and for Houston — areas like energy, health care, space. It just so happens that these areas that Houston and Rice have historically done better at than anyone else — those happen to be the most grand challenges for all of humanity."

Read more and stream the podcast episode here.

This week's innovators to know roundup includes Fiona Mack of JLABS, Grace Rodriguez of Impact Hub Houston, and Emily Cisek of The Postage. Photos courtesy

3 female Houston innovators to know this week

who's who

Editor's note: In today's Monday roundup of Houston innovators, I'm introducing you to three female innovators across industries — from life science to impact innovation.

Fiona Mack, head of JLABS @ TMC

Fiona Mack has joined JLABS @ TMC as head of the incubator. She shares her vision for the lab on this week's episode of the Houston Innovators Podcast. Photo courtesy of JLABS

Fiona Mack is among the latest additions to the Houston innovation ecosystem, as she joined JLABS @ TMC just a few months ago. On her plate right now is assessing the needs of the incubator's 49 member companies in the portfolio and understanding the needs of the Texas innovation ecosystem.

"As I learn more about the history of life science sector in Texas, over the past 20 years there has been an impetuous to build up this critical mass of companies here to really make it a strong hub that competes with the energy sector to make it a pillar of the economy here," Mack says. Read more and stream the podcast interview.

Grace Rodriguez, executive director and CEO of Impact Hub Houston

Grace Rodriguez and her team at Impact Hub Houston is in for a busy week. Courtesy of Impact Hub Houston

Grace Rodriguez has a marathon of a week ahead of her — but it's an exciting one. The fourth annual Houston Innovation Summit is going on now, and she's really passionate about the theme.

"The focus on education and policy is really interesting to me — it's not just about tech and business anymore," Rodriguez says. "It's really about how we are supporting businesses in the face of the pandemic, climate change crises — floods, fires, hurricanes — the entire world is being affected by these crises. ... [We need to focus on] how we are making sure that people are aware of everything that's happening and how we can innovate solutions." Read more about the latest from Impact Hub and what THIS events not to miss.

Emily Cisek, founder of The Postage

The Postage is a new company that uses technology to help ease the experience of afterlife responsibilities for family members. Photo courtesy of The Postage

Three years ago, Emily Cisek was struck with immense grief when she lost three family members back to back. She says she learned first-hand how arduous the process of wrapping up someone's life is and how it can take away from the grieving process.

Cisek's grief planted a seed and she has the idea for The Postage, a digital platform that helps collect information and digital assets in one place to ease with affair planning.

"I think the way The Postage has [made planning more available] it's provided a price point, an understanding and steps involved that are more easily accessible; no matter what age group, what race, what your background is, your religion, anything like that, you're able to sign up," says Cisek. Read more.

Fiona Mack has joined JLABS @ TMC as head of the incubator. She shares her vision for the lab on this week's episode of the Houston Innovators Podcast. Photo courtesy of JLABS

New Houston life science incubator leader is focusing on inclusion in health innovation

houston innovators podcast episode 57

By now, Fiona Mack has worked in a few sectors and stages of health innovation — mostly within oncology and biopharmaceuticals. However, since being named the head of JLABS @ TMC a few months ago, she's jumped headfirst into Houston life science startup incubation.

"I've been kind of drinking from the fire hose. I've really tried to understand the J&J organization, which is quite global in its scope across multiple sector areas," Mack shares on this week's episode of the Houston Innovators Podcast. "On a regional level, I've been focusing on understanding my portfolio."

On her plate right now is assessing the needs of the incubator's 49 member companies in the portfolio. Additionally, she's working on recognizing any gaps in leadership — the position has been vacant around a year and a half since the former head, Tom Luby, transitioned to leading the TMC Innovation Institute — and understanding the needs of the Texas innovation ecosystem.

"As I learn more about the history of life science sector in Texas, over the past 20 years there has been an impetuous to build up this critical mass of companies here to really make it a strong hub that competes with the energy sector to make it a pillar of the economy here," Mack says.

One of the things that's top of mind for Mack is a focus on diversity — both from an entrepreneurship and a representation standpoint.

"From a research perspective, there's a strong effect of having a lack of diversity in a lot of the metrics we're looking at," she shares.

Mack says innovation is driven by data, and data, especially when your using that information to treat a diverse group of people, needs to be representative. And Houston is a great place to make that happen.

"What information are we putting into those datasets? If it only represents a homogenous population, it certainly can't be applied to the real world," Mack says. "There's a need to be much more inclusive into what we're analyzing. Houston, in terms of its population, is highly diverse — and we can speak about it ethnically and from an economic standpoint."

Mack shares more of her big picture vision for JLABS @ TMC on the episode, as well as what her early impressions of Houston have been so far. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

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Axiom Space-tested cancer drug advances to clinical trials

mission critical

A cancer-fighting drug tested aboard several Axiom Space missions is moving forward to clinical trials.

Rebecsinib, which targets a cancer cloning and immune evasion gene, ADAR1, has received FDA approval to enter clinical trials under active Investigational New Drug (IND) status, according to a news release. The drug was tested aboard Axiom Mission 2 (Ax-2) and Axiom Mission 3 (Ax-3). It was developed by Aspera Biomedicine, led by Dr. Catriona Jamieson, director of the UC San Diego Sanford Stem Cell Institute (SSCI).

The San Diego-based Aspera team and Houston-based Axiom partnered to allow Rebecsinib to be tested in microgravity. Tumors have been shown to grow more rapidly in microgravity and even mimic how aggressive cancers can develop in patients.

“In terms of tumor growth, we see a doubling in growth of these little mini-tumors in just 10 days,” Jamieson explained in the release.

Rebecsinib took part in the patient-derived tumor organoid testing aboard the International Space Station. Similar testing is planned to continue on Axiom Station, the company's commercial space station that's currently under development.

Additionally, the drug will be tested aboard Ax-4 under its active IND status, which was targeted to launch June 25.

“We anticipate that this monumental mission will inform the expanded development of the first ADAR1 inhibitory cancer stem cell targeting drug for a broad array of cancers," Jamieson added.

According to Axiom, the milestone represents the potential for commercial space collaborations.

“We’re proud to work with Aspera Biomedicines and the UC San Diego Sanford Stem Cell Institute, as together we have achieved a historic milestone, and we’re even more excited for what’s to come,” Tejpaul Bhatia, the new CEO of Axiom Space, said in the release. “This is how we crack the code of the space economy – uniting public and private partners to turn microgravity into a launchpad for breakthroughs.”

Houston ranks No. 4 for HQ relocations and more innovation news to know

Trending News

Editor's note: The top recent Houston business and innovation news includes a high ranking for Houston HQs, an innovative exoskeleton designed for children with cerebral palsy, and incoming drones for Walmart delivery. Catch up on the 5 most-read InnovationMap stories from the latter half of June 2025 below:

1. Houston ranks among top 5 cities for corporate HQ relocations in new report

Houston attracted 31 new corporate headquarters from 2018 to 2024, according to a new report from CBRE. Photo via Getty Images

The Houston area already holds the title as the country’s third biggest metro hub for Fortune 500 headquarters, behind the New York City and Chicago areas. Now, Houston can tout another HQ accolade: It’s in a fourth-place tie with the Phoenix area for the most corporate headquarters relocations from 2018 to 2024.

During that period, the Houston and Phoenix areas each attracted 31 corporate headquarters, according to new research from commercial real estate services company CBRE. Continue reading.

2. Texas plugs in among states at highest risk for summer power outages in 2025

A new study puts Texas at No. 2 among the states most at risk for power outages this summer. Photo via Getty Images

Warning: Houston could be in for an especially uncomfortable summer.

A new study from solar energy company Wolf River Electric puts Texas at No. 2 among the states most at risk for power outages this summer. Michigan tops the list. Continue reading.

3. Houston team develops innovative soft skeleton for kids with cerebral palsy

UH BRAIN and TIRR Memorial Hermann have developed the MyoStep soft exoskeleton to address motor impairments caused by cerebral palsy. Photo courtesy UH.

A Houston team has introduced the MyoStep soft exoskeleton for children with cerebral palsy.

The soft skeleton aims to address motor impairments caused by cerebral palsy that impact children’s ability to participate in physical activities, self-care and academics. Continue reading.

4. CPRIT grants $22M to bring top cancer researchers to Houston

CPRIT recently granted $93 million to 61 organizations and scientists, including many in Houston, to advance cancer research. Carter Smith/Courtesy of MD Anderson

Several prominent cancer researchers are coming to the Houston area thanks to $22 million in grants recently awarded by the Cancer Prevention and Research Institute of Texas (CPRIT).

The biggest CPRIT recruitment grant — $6 million — went to genetics researcher Jean Gautier. Gautier, a professor of genetics and development at Columbia University’s Institute for Cancer Genetics, is joining the University of Texas MD Anderson Cancer Center to continue his research. Continue reading.

5. California company to launch Walmart drone delivery in Houston

California company to launch Walmart drone delivery in Houston

Walmart Supercenters in Houston will offer Wing drone delivery services by this time next year. Photo courtesy Wing.

California-based Wing will soon touch down in Houston.

The drone delivery company has partnered with Walmart Supercenters in Houston, Atlanta, Charlotte, Orlando and Tampa. According to a news release, Wing’s drone delivery services will be available at 100 Walmart stores across the selected markets by this time next year. Continue reading.

Chevron enters the lithium market with major Texas land acquisition

to market

Chevron U.S.A., a subsidiary of Houston-based energy company Chevron, has taken its first big step toward establishing a commercial-scale lithium business.

Chevron acquired leaseholds totaling about 125,000 acres in Northeast Texas and southwest Arkansas from TerraVolta Resources and East Texas Natural Resources. The acreage contains a high amount of lithium, which Chevron plans to extract from brines produced from the subsurface.

Lithium-ion batteries are used in an array of technologies, such as smartwatches, e-bikes, pacemakers, and batteries for electric vehicles, according to Chevron. The International Energy Agency estimates lithium demand could grow more than 400 percent by 2040.

“This acquisition represents a strategic investment to support energy manufacturing and expand U.S.-based critical mineral supplies,” Jeff Gustavson, president of Chevron New Energies, said in a news release. “Establishing domestic and resilient lithium supply chains is essential not only to maintaining U.S. energy leadership but also to meeting the growing demand from customers.”

Rania Yacoub, corporate business development manager at Chevron New Energies, said that amid heightening demand, lithium is “one of the world’s most sought-after natural resources.”

“Chevron is looking to help meet that demand and drive U.S. energy competitiveness by sourcing lithium domestically,” Yacoub said.

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This article originally appeared on EnergyCapital.

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