Meet 6 mentors who are helping the Houston startup scene flourish

meet the finalists

The 2025 Mentor of the Year will be announced on Nov. 13. Courtesy photos

Few founders launch successful startups alone — experienced and insightful mentors often play an integral role in helping the business and its founders thrive.

The Houston startup community is home to many mentors who are willing to lend an ear and share advice to help entrepreneurs meet their goals.

The Mentor of the Year category in our 2025 Houston Innovation Awards will honor an individual like this, who dedicates their time and expertise to guide and support budding entrepreneurs. The award is presented by Houston City College Northwest.

Below, meet the six finalists for the 2025 award. They support promising startups in the medical tech, digital health, clean energy and hardware sectors.

Then, join us at the Houston Innovation Awards this Thursday, Nov. 13 at Greentown Labs, when the winner will be unveiled. The event is just days away, so secure your seats now.

Anil Shetty, InformAI

Anil Shetty serves as president and chief medical officer for biotech company Ferronova and chief innovation officer for InformAI. He's mentored numerous medical device and digital health companies at seed or Series A, including Pathex, Neurostasis, Vivifi Medical and many others. He mentors through organizations like Capital Factory, TMC Biodesign, UT Venture Mentoring, UTMB Innovation and Rice's Global Medical Innovation program.

"Being a mentor means empowering early-stage innovators to shape, test, and refine their ideas with clarity and purpose," Shetty says. "I’m driven by the opportunity to help them think strategically and pivot early before resources are wasted. At this critical stage, most founders lack the financial means to bring on seasoned experts and often haven’t yet gained real-world exposure. Mentorship allows me to fill that gap, offering guidance that accelerates their learning curve and increases the chances of meaningful, sustainable impact."

Jason Ethier, EnergyTech Nexus

Jason Ethier is the founding partner of EnergyTech Nexus, through which he has mentored numerous startups and Innovation Awards finalists, including Geokiln, Energy AI Solutions, Capwell Services and Corrolytics. He founded Dynamo Micropower in 2011 and served as its president and CEO. He later co-founded Greentown Labs in Massachusetts and helped bring the accelerator to Houston.

"Being a mentor means using my experience to help founders see a clearer path to success. I’ve spent years navigating the ups and downs of building companies, struggling with cash flow, and making all the mistakes; mentoring gives me the chance to share those lessons and show entrepreneurs the shortcuts I wish I’d known earlier," Ethier says. "At Energytech Nexus, that role goes beyond just helping individual founders — it’s about creating a flywheel effect for Houston’s entire innovation ecosystem."

Jeremy Pitts, Activate Houston

Jeremy Pitts serves as managing director of Activate Houston, which launched in Houston last year. He was one of the founders of Greentown Labs in the Boston area and served in a leadership role for the organization between 2011 and 2015. Through Activate, he has mentored numerous impactful startups and Innovation Awards finalists, including Solidec, Coflux Purification, Bairitone Health, Newfound Materials, Deep Anchor Solutions and others.

"Being a mentor to me is very much about supporting the person in whatever they need. Oftentimes that means supporting the business—providing guidance and advice, feedback, introductions, etc," But just as important is recognizing the person and helping them with whatever challenges they are going through ... Sometimes they need a hype man to tell them how awesome they are and that they can go do whatever hard thing they need to do. Sometimes they just need an empathetic listener who can relate to how hard these things are. Being there for the person and supporting them on their journey is key to my mentorship style."

Joe Alapat, Liongard

Joe Alapat founded and serves as chief strategy officer at Houston software company Liongard and chief information officer at Empact IT, which he also owns. He mentors through Founder Fridays Houston Group, Software Day by Mercury Fund, SUPERGirls SHINE Foundation, Cup of Joey and at the Ion. He's worked with founders of FlowCare, STEAM OnDemand, Lokum and many other early stage startups.

"Being a mentor to me means unleashing an individual’s 10x—their purpose, their ikigai (a Japanese concept that speaks to a person’s reason for being)," Alapat says. "Mentoring founders in the Houston community of early stage, high-growth startups is an honor for me. I get to live vicariously through a founder’s vision of the future. Once they show me that compelling vision, I’m drawn to bring the future forward with them so the vision becomes reality with a sense of urgency."

Neal Dikeman, Energy Transition Ventures

Neal Dikeman serves as partner at early stage venture fund Energy Transition Ventures, executive in residence at Greentown Labs, and offices in and supports Rice Nexus at the Ion. He mentors startups, like Geokiln, personally. He also mentored Helix Earth through Greentown Labs. The company went on to win in the Smart Cities, Transportation & Sustainability contest at SXSW earlier this year. Dikeman has helped launch several successful startups himself, most recently serving on the board of directors for Resilient Power Systems, which was acquired by Eaton Corp for $150 million.

"Founders have to find their own path, and most founders need a safe space where they can discuss hard truths outside of being 'on' in sales mode with their team or board or investors, to let them be able to work on their business, not just in it," Dikeman says.

Nisha Desai, Intention

Nisha Desai serves as CEO of investment firm Intention and mentors through Greentown Labs, TEX-E, Open Minds, the Rice Alliance Clean Energy Accelerator, Avatar Innovations and The Greenhouse. She currently works with founders from Solidec, Deep Anchor Solutions, CLS Wind and several other local startups, several of which have been nominated for Innovation Awards this year. She's served a board member for Greentown Labs since 2021.

"When I first started mentoring, I viewed my role as someone who was supposed to prevent the founder from making bad decisions. Now, I see my role as a mentor as enabling the founder to develop their own decision-making capability," Desai says. "Sometimes that means giving them the space to make decisions that might be good, that might be bad, but that they can be accountable for. At the end of the day, being a mentor is like being granted a place on the founder's leadership development journey, and it's a privilege I'm grateful for."

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.

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Meet Michelle Accardi, the new CEO of Liongard. Photo courtesy of Liongard

Houston SaaS startup names new CEO

c-suite switchup

A Houston startup founder is transitioning from CEO to make room for a new leader.

Liongard, a software-as-a-service startup with a Managed Service Providers platform, has named Michelle Accardi as CEO, effective April 17. Joe Alapat, co-founder and CEO, will transition to CTO to better lead tech development of the platform, which provides customers with compliance, cybersecurity risk mitigation, and more.

“Now is the right time for Liongard to transform for the long term as we welcome a new member to our executive leadership team,” Alapat says in a news release. “Michelle’s addition will help take Liongard to the next level and accelerate our growth as we address the evolving needs of the industry. This new role allows me to focus on driving Liongard’s innovation forward and helping our MSP partners navigate the modern business landscape.”

Accardi has over 20 years of experience within MSPs and technology companies. She will oversee growth of the company and its product portfolio.

“The Liongard team has accomplished much in its first few years, and that’s a testament to the founding vision and hard work of the entire organization,” Accardi said. “With Liongard in a strong market leadership position, there is a unique opportunity to accelerate growth. Joe and team have built a dynamic company culture and robust technical foundation and I am looking forward to partnering with him to build on the company’s success.”

Most recently as CEO of Logically, Accardi also served as president and chief revenue officer of Star2Star.

“We are excited to welcome Michelle to the team at Liongard,” says Carter Griffin, Liongard board member and general partner at Updata Partners, an investor of Liongard. “We believe that Michelle’s leadership experience and excellent track record will ensure Liongard continues to perform at a very high level.”

Accardi joins the team following a $10 million round of funding that Liongard, which was founded in 2015, secured last year. The startup has raised over $30 million in investment funding to date.

Joe Alapat has transitioned to CTO of Houston-based Liongard. Photo courtesy of Liongard

This week's roundup of Houston innovators includes Sam Dike of Rice Management Company, Barbara Burger of Greentown Labs, and Joe Alapat of Liongard. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from clean energy to software — recently making headlines in Houston innovation.


Sam Dike, manager of strategic initiatives at Rice Management Company

Sam Dike of Rice Management Company joins the Houston Innovators Podcast to discuss the past, present, and future of Houston's rising Ion Innovation District. Photo via rice.edu

A few years ago, Rice Management Company saw an opportunity a few years back to make an investment in Houston's nascent innovation and tech ecosystem, and announced the plans for the Ion, a 266,000-square-foot innovation hub in an renovated and rehabilitated Sears.

"In some ways innovation is not necessarily about creating something completely new — it's oftentimes building upon something that exists and making it better," says Sam Dike, manager of strategic initiatives at Rice Management Company, on the most recent episode of the Houston Innovators Podcast. "I think that's what we've done with the building itself.

"We took something that had really strong bones and a strong identity here in Houston," he continues, "and we did something that's often atypical in Houston and preserved and repurposed it — not an easy logistical or financial decision to make, but we believed it was the best for Houston and for the project." Click here to read more and stream the podcast.

Barbara Burger, board member at Greentown Labs

Barbara Burger, former president of Chevron Technology Ventures, has been named to the Greentown Labs board of directors. Photo courtesy of CTV

Greentown Labs announced that it has appointed Barbara J. Burger — former vice president of innovation and president of Chevron Technology Ventures, Chevron's startup investment arm — to its board of directors.

In her previous role at Chevron, she spearheaded the energy company's support of Greentown Labs since 2013 and the opening of its Houston incubator. After announcing her retirement in December, she has continued being active at Greentown and hosts semi-annual Women of Greentown Houston dinners.

“I am honored and excited to join the Greentown Labs Board of Directors,” says Burger in the release. “Combatting the effects of climate change requires bringing a wide range of innovative solutions to scale. There is work for incumbents and startups alike in this enormous challenge that WE all face. Greentown Labs plays an essential role in providing facilities, tools, programs, and an inclusive community to nurture and grow innovation that matters.” Click here to continue reading.

Joe Alapat, co-founder and CEO of Liongard

Houston IT company forms new partnership

Houston-based Liongard has fresh funding to work with. Courtesy of Liongard

Liongard, an IT software provider, has raised an additional $10 million in funding, according to a news release, will go toward providing the best customer service for Liongard's growing customer base.

The technology is providing managed service providers, or MSPs, improved visibility across the IT stack and an optimized user experience.

“Since working with our first MSP partners, we’ve seen time and again the power of visibility into IT data, reducing the time they spend researching customer issues and allowing them to respond faster than their peers,” says Joe Alapat, CEO and co-founder of Liongard, in the release. “This investment enables us to continue to achieve our vision of delivering visibility into each element of the IT stack.” Click here to continue reading.

Houston-based Liongard has fresh funding to work with. Photo via Getty Images

Houston SaaS startup raises $10M to keep up with customer growth

money moves

A Houston software company has announced its latest funding.

Liongard, an IT software provider, has raised an additional $10 million led by Updata Partners with contribution from TDF Ventures — both existing investors in the company. The funding, according to a news release, will go toward providing the best customer service for Liongard's growing customer base.

The technology is providing managed service providers, or MSPs, improved visibility across the IT stack and an optimized user experience.

“Since working with our first MSP partners, we’ve seen time and again the power of visibility into IT data, reducing the time they spend researching customer issues and allowing them to respond faster than their peers,” says Joe Alapat, CEO and co-founder of Liongard, in the release. “This investment enables us to continue to achieve our vision of delivering visibility into each element of the IT stack.”

The company has about 2,000 partners in support of more than 60,000 end customers. And has been recognized as a top employer by Forbes and Inc. magazine earlier this year.

“We are excited to deepen our commitment with Liongard,“ says Carter Griffin, general partner at Updata, in the release. “With its leading data platform for MSPs we expect continued fast-paced growth.”

Liongard's last funding round was in May of 2020 and was a $17 million series B round. Both Updata Partners and TDF ventures were involved in that round. The company's total funding now sits at over $30 million.

These three Houston businesses rank as great workplaces. Photo via Getty Images

3 Houston tech companies land on Inc.'s list of the best places to work

If you’re hunting for a new job, you might want to check out nine Austin-based companies that have been named among the best workplaces in the U.S.

On May 10, Inc. magazine released its 2022 list of the 475 best workplaces in the country, 22 of which are in Texas, including the nine in Austin.

After collecting data from thousands of submissions, Inc. chose honorees that best represented dedication to “redefining and enriching the workplace in the face of the pandemic,” says Scott Omelianuk, the magazine’s editor in chief.

“Not long ago, the term ‘best workplace’ would have conjured up images of open-office designs with stocked snack fridges,” says Omelianuk in a news release. “Yet given the widespread adoption of remote work, the concept of the workplace has shifted. This year, Inc. has recognized the organizations dedicated to redefining and enriching the workplace in the face of the pandemic.”

Each nominated company participated in an employee survey conducted by Quantum Workplace that touched on factors like management effectiveness, perks, employees’ professional growth, and company culture.

The three Houston-based winners are:

  • Liongard, a Houston-based provider of an IT automation platform
  • QTS, a Tomball-based provider of physical and electronic security services
  • WizeHire, a Houston-based provider of HR software

“We are honored to be recognized again as Best Place to Work by Inc. We have built an amazing team that has quickly accelerated our growth while continuing to rapidly improve our product and respond to our ever-improving understanding of our customers’ needs,” says Joe Alapat, Liongard founder and CEO, in a news release. “Our core values drive how we work and who we hire, and it’s the Liongard employees who guide our culture. We have an amazing team that shares the common goal of building something great – and that starts from the inside.”

Here are the other Texas companies that made the cut.

Dallas-Fort Worth

  • 5, an Irving-based energy advisory firm
  • Bestow, a Dallas-based life insurance company
  • Embark, a Dallas-based business advisory firm
  • Idea Grove, a Dallas-based marketing and PR firm
  • JB Warranties, an Argyle-based provider of HVAC and plumbing warranties
  • MB Group, a Plano-based accounting firm
  • The Power Group, a Dallas-based PR firm
  • The Vested Group, a Plano-based IT consulting company
  • TimelyMD, a Fort Worth-based telehealth company that focuses on students

Austin

  • Abilitie, a provider of virtual mini-MBAs and leadership simulations
  • Apty, a provider of web-based software for large companies
  • Cartograph, a consulting firm for brands in the organic and natural foods industry
  • Corvia, a provider of technology for the financial services industry
  • Homeward, a provider of financing for home purchases
  • INK Communications, a marketing and PR firm
  • Osano, a provider of data privacy software
  • Praetorian, a cybersecurity company
  • Scribe Media, a platform for self-published authors

Tyler

  • Education Advanced, a provider of education software
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This article originally ran on CultureMap.

In the latest round up of Houston innovation news you may have missed, an offshore robotics company has rebranded, two startups earned bragging rights, and more. Photo via Getty Images

Houston robotics company rebrands, startups snag​  international spotlights, and more local innovation news

short stories

Houston startups have had a busy fourth quarter so far with exciting news from all around the local innovation ecosystem.

In this roundup of short stories within Houston innovation, a pair of Houston startups receive national and international praise, a local robotics company rebrands, Houston Community College receives funding for BIPOC female founders, and more.

Houston-area robotics company rebrands

Nicolaus Radford is the founder of Nauticus Robotics Inc., neé Houston Mechatronics. Photo courtesy

Houston Mechatronics Inc. based in Webster, Texas, announced that it has rebranded its offshore robotics firm as Nauticus Robotics Inc.

"The name Nauticus Robotics makes clear our commitment to the blue economy," says Nicolaus Radford, the company's founder and CEO, in a news release. "Our mission is to grow that economy through sustainable robotics that deliver value while protecting our planet's most valuable resources. This rebrand aligns us with that goal and positions us as a leader in our space."

The company has also launched a new website, representing an expanded vision of "Green robotics for a blue economy," according to the news release.

"Our new website will really lead the charge for us on the sales side," says Todd Newell, senior vice president of business development at Nauticus Robotics, in the release. "Prospective customers can get an overview of our robotics and their capabilities. If they desire, they can download detailed specifications to see how a product might fit into their operations. And we've made it very easy for those interested in a demo or a call to quickly get in touch with our team."

Houston IT company forms new partnership

Joe Alapat is the CEO of Houston-based Liongard. Courtesy of Liongard

Liongard has formed a new partnership with email defense solution Vade to release a new tool for its users. The feature automatically surfaces critical account data, streamlining user management, and billing for M365 users, according to a news release.

"I'm very pleased that Vade for M365 is now integrated with Liongard's leading IT automation platform," says Adrien Gendre, chief technology and product officer at Vade, in the release. "MSPs who offer managed cybersecurity can now combine the threat detection and remediation capabilities of Vade for M365 with the automation and unified visibility of Liongard. Together, Liongard and Vade for M365 give MSPs the tools they need to save time, improve efficiencies, and grow their businesses."

The tool is already included in Liongard’s latest release and users can leverage licensing, billing, and security data to simplify security management, accounting, and reporting.

“We’re very excited about our new Vade Inspector and the value it brings to the MSP community,” says Matt Miller, vice president of product for Liongard. “Both Vade and Liongard are committed to helping the managed services community stay security-focused. This Inspector enables MSPs to maintain a strong security posture through automation, with the added benefit of saving time and effort across the organization.”

Houston startup snags national spotlight

Cobalt's founders wanted to avoid harsh alcoholic smells and opted for calming and fun scents. Photo courtesy of Cobalt

Southern Living magazine's December issue features the annual holiday gift guide, and making the list this year is Houston-based small business Cobalt's Crisp Peppermint Hand Sanitizer.

“We are beyond thrilled to be included in Southern Living magazine with the best company,” says Christina Milligan, co-founder of Cobalt, in a news release. “It’s so exciting to see how much Cobalt has grown in the past 12 months. The idea has surpassed the pandemic and become an everyday necessity for healthy lifestyles. What started out as blending and filling each bottle from our kitchen tables has evolved into corporate partnerships, multiple scents, and new product lines. We are so grateful for all of our customers across the country and look forward to the next phase of Cobalt.”

Milligan and Molly Voorhees launched Cobalt in November 2020 with a line of personal-sized surface cleaners, hand sanitizers, and travel kits.

Cobalt is the only Houston-based company in the 2021 guide, according to the release. The issue is on newsstands now.

Houston blockchain company wins startup of the year

Data Gumbo's team was recognized internationally for its impact. Courtesy of Data Gumbo

Data Gumbo, which has created an industrial smart contract network company, announced last month that it has been named the Oil and Gas Start Up Company of the Year at the Abu Dhabi International Petroleum Exhibition and Conference Awards Gala — the largest annual oil and gas awards event in the Middle East.

According to a news release from the company, "Data Gumbo was recognized for its potential to reshape the energy industry based on its continued innovation, strong business model and the impressive impact of its global industrial smart contract network."

“Our industrial smart contract network, GumboNet, offers the new gold standard for organizations to execute business better through guaranteed transactional certainty across commercial relationships,” says Andrew Bruce, CEO and founder of Data Gumbo. “It’s an honor to be recognized by ADIPEC for our work and commitment to expanding our network across the global energy industry, allowing companies to eliminate the lack of trust in industrial sectors, streamline contract execution and capture significant cost savings.”

The 11th annual ADIPEC Awards' judges reviewed more than 700 entries from over 50 countries across digitalization, sustainability, research, innovation and more. For more info on the ADIPEC Awards, click here.

Houston university system receives $750,000 grant to drive women-owned business success

HCC has fresh funds to support female entrepreneurs. Photo via Getty Images

Wells Fargo granted $750,000 to Houston Community College to support the new Open for Business program aimed at empowering women-owned businesses in the Houston region. The grant is part of a $420 million small business recovery effort by Wells Fargo to support nonprofit and educational organizations assisting women of color in overcoming longstanding obstacles to entrepreneurship.

“We are delighted to broaden our programs to help women succeed in owning and operating businesses,” says Maya Durnovo, HCC’s chief entrepreneurial officer, in a news release, adding that the program has a particular focus on African American, Indo-American, Hispanic, Asian and Native American women.

The Open for Business Program – led by Director Tamala Austin – is already staffed with more than 165 women registered in the program.

“We can only imagine what kinds of businesses might have taken off, what products consumers might have enjoyed and what returns might have been realized had women and people of color enjoyed equal access to capital and opportunity,” Durnovo says in the release.

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Innovative Houston research leads our top health tech news of 2025

year in review

Editor's note: As 2025 comes to a close, we're looking back at the stories that defined Houston innovation this year. The Bayou City continued to grow as a health tech hub, bringing in a multibillion-dollar pharmaceutical development, playing home based to startups developing innovative treatment options and attracting leading researchers and professionals to the city. Here are the 10 most-read Houston health tech stories of the year:

Houston Nobel Prize nominee earns latest award for public health research

Dr. Peter Hotez with Dr. Maria Elena Bottazzi. Photo courtesy of TMC

Houston vaccine scientist Dr. Peter Hotez is no stranger to impressive laurels. In 2022, he was nominated for a Nobel Peace Prize for his low-cost COVID vaccine.

His first big win of 2025 was this year’s Hill Prize, awarded by the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST). Hotez and his team were selected to receive $500,000 from Lyda Hill Philanthropies to help fund The Texas Virosphere Project, which aims to create a predictive disease atlas relating to climate disasters. Rice University researchers are collaborating with Hotez and his team on a project that combines climate science and metagenomics to access 3,000 insect genomes. The goal is to aid health departments in controlling disease and informing policy. Continue reading.

U.S. News ranks Houston hospital No. 1 in Texas for 14th year in a row

Houston Methodist is once again the top hospital in Texas. Photo via Houston Methodist

U.S. News & World Report's 2025 rankings of the best hospitals in Texas prove that Houston is in good hands.

The esteemed Houston Methodist Hospital was rated the No. 1 best hospital in Texas for the 14th consecutive year, and the No. 1 hospital in the metro area. Eleven more Houston-area hospitals earned spots among the statewide top 35. Continue reading.

Eli Lilly to build $6.5B pharmaceutical factory at Generation Park

Eli Lilly is expected to bring a $6.5 billion manufacturing facility to Houston by 2030. Rendering courtesy Greater Houston Partnership.

Pharmaceutical giant Eli Lilly and Co. plans to build a $6.5 billion manufacturing plant at Houston’s Generation Park. More than 300 locations in the U.S. competed for the factory.

The Houston site will be the first major pharmaceutical manufacturing plant in Texas, according to the Greater Houston Partnership. Lilly said it plans to hire 615 full-time workers for the 236-acre plant, including engineers, scientists and lab technicians. The company will collaborate with local colleges and universities to help build its talent pipeline. Continue reading.

How a Houston company is fighting anxiety, insomnia & Alzheimer’s through waveforms

Nexalin develops non-invasive devices that help reset networks in the brain associated with symptoms of anxiety and insomnia. Photo via Getty Images.

Houston-based Nexalin Technology is taking a medicine-free approach to target brain neurologically associated with mental illness. The company's patented, FDA-cleared frequency-based waveform targets key centers of the midbrain. Delivered via a non-invasive device, the treatment gently stimulates the hypothalamus and midbrain, helping to “reset networks associated with symptoms” of anxiety and insomnia.

Nexalin’s proprietary neurostimulation device moved forward with a clinical trial that evaluated its treatment of anxiety disorders and chronic insomnia in Brazil this year and enrolled the first patients in its clinical trial at the University of California, San Diego. Continue reading.

Houston doctor aims to revolutionize hearing aid industry with tiny implant

Houston Methodist's Dr. Ron Moses has created NanoEar, which he calls “the world’s smallest hearing aid.” Photo via Getty Images.

“What is the future of hearing aids?” That’s the question that led to a potential revolution.

Dr. Ron Moses, an ENT specialist and surgeon at Houston Methodist, is the creator of NanoEar, which he calls “the world’s smallest hearing aid.” NanoEar is an implantable device that combines the invisibility of a micro-sized tympanostomy tube with more power—and a superior hearing experience—than the best behind-the-ear hearing aid. Continue reading.

Houston scores $120M in new cancer research and prevention grants

The Cancer Prevention and Research Institute of Texas doled out 73 more grants to health care systems and companies in the state in November. Carter Smith/Courtesy of MD Anderson

The Cancer Prevention and Research Institute of Texas granted more than $120 million to Houston organizations and companies as part of 73 new awards issued statewide this fall. The funds are part of nearly $154 million approved by the CPRIT's governing board, bringing the organization's total investment in cancer prevention and research to more than $4 billion since its inception. A portion of the funding will go toward recruiting leading cancer researchers to Houston. Continue reading.

Digital Health Institute's new exec director aims to lead innovation and commercialization efforts

Pothik Chatterjee was named executive director of Rice University's and Houston Methodist's Digital Health Institute, effective May 1. Photo courtesy Rice University.

The Digital Health Institute, a joint venture between Rice University and Houston Methodist, appointed Pothik Chatterjee to the role of executive director this summer. Chatterjee’s role is to help grow the collaboration between the institutions, but the Digital Health Institute already boasts more than 20 active projects, each of which pairs Rice faculty and Houston Methodist clinicians. Once the research is in place, it’s up to Chatterjee to find commercial opportunities within the research portfolio. Those include everything from hospital-grade medical imaging wearables to the creation of digital twins for patients to help better treat them. Continue reading.

Innovation Labs @ TMC set to launch for early-stage life science startups

Innovation Labs @ TMC will open next year at the TMC Innovation Factory. Photo courtesy JLABS.

The Texas Medical Center announced its plans to launch its new Innovation Labs @ TMC in January 2026 to better support life science startups working within the innovation hub. The 34,000-square-foot space, located in the TMC Innovation Factory at 2450 Holcombe Blvd., will feature labs and life science offices and will be managed by TMC. The expansion will allow TMC to "open its doors to a wider range of life science visionaries." Continue reading.

6 Houston health tech startups making major advancements right now

Tatiana Fofanova and Dr. Desh Mohan, founders of Koda Health. Photo courtesy Koda Health.

The Health Tech Business category in our 2025 Houston Innovation Awards honored innovative startups within the health and medical technology sectors. Six forward-thinking businesses were named finalists for the 2025 award, ranging from an end-of-life care company to others developing devices and systems for heart monitoring, sleep apnea, hearing loss and more. Continue reading or see who won here.

Houston students develop cost-effective glove to treat Parkinson's symptoms

Rice University students Emmie Casey and Tomi Kuye used smartphone motors to develop a vibrotactile glove. Photo by Gustavo Raskosky/ Courtesy Rice University.

Two Rice undergraduate engineering students have developed a non-invasive vibrotactile glove that aims to alleviate the symptoms of Parkinson’s disease through therapeutic vibrations. Emmie Casey and Tomi Kuye developed the project with support from the Oshman Engineering Design Kitchen (OEDK). The team based the design on research from the Peter Tass Lab at Stanford University, which explored how randomized vibratory stimuli delivered to the fingertips could help rewire misfiring neurons in the brain—a key component of Parkinson’s disease. Continue reading.

Houston hailed as one of America's 10 best cities for startups

Startup Report

Houston's favorable economic climate is enticing new opportunities for entrepreneurship and growth, and now the city is being hailed as the 7th-best U.S. city for starting a business.

The recognition comes in CommercialCafe's recent "Best Cities for Startups" report, published December 10. The study analyzed large U.S. cities across two population categories – cities with more than 1 million residents and cities with populations between 500,000 and 1 million residents. The report analyzed relevant metrics such as office or coworking costs, Kickstarter funding success, startup density, and survival rates, among others.

Across the biggest U.S. cities with over a million residents, Phoenix, Arizona landed on top as the No. 1 best place to start a new business.

The report's findings revealed 10.6 percent of all businesses in Houston are startups that have been active for less than a year. These new businesses have a survival rate of 64.5 percent, meaning just under two-thirds of all startups in the city will still be running up to five years after they were first established.

Over the last five years, the number of new businesses established in Houston has grown nearly 15 percent. CommercialCafe said new businesses in cities with high startup growth rates tend to "attract top talent" which can eventually lead to securing "vital funding for expansion."

Independent professionals – also known as freelancers – are another crucial resource for new businesses that may need "specialized services" for a fixed amount of time, the report said. Houston's freelance workforce has grown about 9 percent from 2019-2023, and the analysis found there were 97,295 freelancers working in Houston in 2023, compared to 89,528 in 2019.

"Generally, cities in the South and Southwest have experienced strong growth during the surveyed period, in contrast to California cities like Los Angeles and San Diego, where the share of freelancers and gig workers has either stagnated or slightly declined," the report said.

Houston boasts the second-cheapest office space rent nationally, the report found. The average asking price for a 1,000-square-foot workspace (for five employees) in the city added up to $27,124 annually. For startups that want greater flexibility for their workers, the annual cost for a coworking space for the same number of employees in Houston came out to $13,200, which is the fourth-most affordable rate in the U.S.

Other Texas cities with attractive economic environments for startups

Texas, as a whole, is one of the strongest states for starting a new business. Other than Houston, San Antonio (No. 2), Dallas (No. 3), and Fort Worth (No. 4) were also recognized among the top 10 best places to start a business in the category of U.S. cities with more than a million residents.

Austin topped a separate ranking of best cities to start a business with 500,000 to 1 million residents.

"Specifically, the Texas capital was the frontrunner for indicators that looked at the overall share of startups within the local economy, as well as growth rates in five years (2019 to 2023)," the report said. "On top of that, Austin also topped the rankings for its percentage of college-educated residents and its consulting firms, which provide vital support for burgeoning enterprises."

The top 10 best cities to start a new business are:

  • No. 1 – Phoenix, Arizona
  • No. 2 – San Antonio, Texas
  • No. 3 – Dallas, Texas
  • No. 4 – Fort Worth, Texas
  • No. 5 – Jacksonville, Florida
  • No. 6 – San Diego, California
  • No. 7 – Houston, Texas
  • No. 8 – Philadelphia, Pennsylvania
  • No. 9 – Chicago, Illinois
  • No. 10 – Los Angeles, California
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This article originally appeared on CultureMap.com.

Top Houston space news of 2025 soars with NASA deals, lunar missions

Year in Review

Editor's note: As 2025 comes to a close, we're looking back at the stories that defined Houston innovation this year. The space tech sector soared with companies landing huge NASA contracts and furthering their lunar missions. Here are the 10 biggest Houston space tech stories of the year:

Houston native picked for 2025 class of NASA astronaut candidates

Houston native Anna Menon, posing below the first A in “NASA,” is one of 10 new NASA astronaut candidates. Photo courtesy NASA.

NASA has selected 10 new astronaut candidates, including one whose hometown is Houston, for its 2025 training class. The candidates will undergo nearly two years of training before they can assume flight assignments.

Intuitive Machines lands $9.8M to complete orbital transfer vehicle

Intuitive Machines expects to begin manufacturing and flight integration on its orbital transfer vehicle as soon as 2026. Photo courtesy Intuitive Machines.

Houston-based Intuitive Machines, which rang the NASDAQ opening bell July 31, secured a $9.8 million Phase Two government contract for its orbital transfer vehicle. The contract will push the project through its Critical Design Review phase, which is the final engineering milestone before manufacturing can begin.

Houston tech company tapped by NASA for near space initiative

Intuitive Machines is among four companies awarded contracts for NASA’s Near Space Network. Photo via intuitivemachines.com

In January, Intuitive Machines nailed down a NASA deal to expand the agency’s communications network for spacecraft. Additionally, NASA completed the first round of “human in the loop” testing for Intuitive Machines’ Moon RACER lunar terrain vehicle at the agency’s Johnson Space Center. RACER (Reusable Autonomous Crewed Exploration Rover) is one of three commercially developed unpressurized lunar terrain vehicles being considered for NASA’s Artemis lunar initiative.

Texas Space Commission doles out $5.8 million to Houston companies

Axiom Space and FluxWorks are the latest Houston-area companies to receive funding from the Texas Space Commission. Photo via Getty Images.

Two Houston-area companies landed more than $5.8 million in funding from the Texas Space Commission. The commission granted up to $5.5 million to Houston-based Axiom Space and up to $347,196 to Conroe-based FluxWorks in June 2025. The two-year-old commission previously awarded $95.3 million to 14 projects. A little over $34 million remains in the commission-managed Space Exploration and Aeronautics Research Fund.

Houston company awarded $2.5B NASA contract to support astronaut health and space missions

NASA has awarded KBR a five-year, $2.5 billion Human Health and Performance Contract. Photo courtesy NASA.

Houston-based technology and energy solution company KBR was awarded a $2.5 billion NASA contract to support astronaut health and reduce risks during spaceflight missions. Under the terms of the Human Health and Performance Contract 2, KBR will provide support services for several programs, including the Human Research Program, International Space Station Program, Commercial Crew Program, Artemis campaign and others. This will include ensuring crew health, safety, and performance; occupational health services and risk mitigation research for future flights.

Houston engineering firm lands $400M NASA contract

Bastion Technologies has been tapped to provide safety and mission services for NASA's Marshall Space Flight Center in Alabama. Photo via nasa.gov.

NASA granted Houston-based Bastion Technologies Inc. the Safety and Mission Assurance II (SMAS II) award with a maximum potential value of $400 million. The award stipulates that the engineering and technical services company provide safety and mission services for the agency’s Marshall Space Flight Center in Huntsville, Alabama.

Houston startups win NASA funding for space tech projects

Houston startups were recently named among the nearly 300 recipients that received a portion of $44.85 million from NASA to develop space technology. Photo via NASA/Ben Smegelsky

Three Houston startups were granted awards from NASA in July 2025 to develop new technologies for the space agency. The companies were among nearly 300 recipients that received a total agency investment of $44.85 million through the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I grant programs.

Texas Republicans are pushing to move NASA headquarters to Houston

Here's why Texas Republicans think NASA's headquarters should move to Texas in 2028. File photo.

Two federal lawmakers from Texas spearheaded a campaign to relocate NASA’s headquarters from Washington, D.C., to the Johnson Space Center in Houston’s Clear Lake area. Houston faces competition on this front, though, as lawmakers from two other states are also vying for this NASA prize. With NASA’s headquarters lease in D.C. set to end in 2028, U.S. Sen. Ted Cruz, a Texas Republican, and U.S. Rep. Brian Babin, a Republican whose congressional district includes the Johnson Space Center, wrote a letter to President Trump touting the Houston area as a prime location for NASA’s headquarters.

Intuitive Machines to acquire NASA-certified deep space navigation company

Intuitive Machines will acquire Kinetx, which marks its entry into the precision navigation and flight dynamics segment of deep space operations. Photo via Getty Images.

In August 2025, Intuitive Machines agreed to buy Tempe, Arizona-based aerospace company KinetX for an undisclosed amount. The deal is expected to close by the end of this year. KinetX specializes in deep space navigation, systems engineering, ground software and constellation mission design. It’s the only company certified by NASA for deep space navigation. KinetX’s navigation software has supported both of Intuitive Machines’ lunar missions.

Axiom Space launches semiconductor and astronaut training initiatives

Axiom Space chief astronaut Michael López-Alegría (left) trains with Axiom’s new “Project Astronaut,” Emiliano Ventura. Photo courtesy of Axiom Space.

In fall 2025, Axiom Space, a Houston-based commercial spaceflight and space infrastructure company, launched initiatives in two very different spheres — semiconductors and astronaut training.

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