JLABS-based cancer therapies company closes $15.5M series A led by Houston bioventure

fresh funds

After a recent raise, this Houston biotech company is headed to first-in-human clinical trials. Photo via stellanovatx.com

Houston-based Stellanova Therapeutics closed a $15.5 million series A financing this month, which will advance the company's first-in-human clinical trials for oncology and help build out its team.

Stellanova is a resident company at Johnson & Johnson's biotech incubator in the TMC (JLABS @ TMC) and is one of four entities that make up cancer and disease biotech company Sporos Bioventures, which officially launched last month after closing a $38.1 million series A of its own.

Stellanova is focused on advancing therapies for cancers that are resistant to current treatments, like chemotherapy and immune therapies. According to a release, it has seen unprecedented anti-tumor activity in preclinical models of pancreas and triple negative breast cancer through the use of its lead antibody, which targets DKK3, a factor secreted by cancer-associated fibroblasts that spur tumors.

The company was founded based on research out of Dr. Rosa Hwang's lab at Houston's MD Anderson Cancer Center.

"We are thrilled to bring Stellanova into the Sporos group of companies. Stellanova means 'new star,' and it is clear the Stellanova team embraces this namesake with their entirely new approach to treating cancer," Harold Levy, Stellanova and Sporos founder and board member said in the statement. "We have been impressed by Stellanova's accomplishments and look forward to being involved in the advancement of the company's platform, one that we believe has the potential to directly combat the most devastating of cancers."

In conjunction with the financing, Stellanova also announced that it has named JLABS @ TMC founding team member Emmanuelle Schuler as the company's inaugural CEO.

Stellanova joins Sporos's Tvardi Therapeutics as it moves toward clinical trials. Tvardi, named a "most promising" by BioHouston and the Rice Alliance in December, is in Phase 1 clinical trial of its STAT3 oral inhibitor for treatment of cancer, inflammation and fibrosis.

Asylia Therapeutics and Nirogy Therapeutics were also founding entities of Sporos. The companies are in the proof of concept and discovery phases and focus on cancer, autoimmune diseases, infectious diseases, and inflammatory diseases.

The city's top power players within Houston's energy innovation ecosystem joined virtual SXSW to discuss Houston's life science innovation scene and developing an inclusive ecosystem. Photos courtesy

Overheard: Houston's innovation leaders weigh in on the city's developing ecosystem at SXSW

EAVESDROPPING ONLINE

Another day of SXSW 2021 has concluded, and just like the first day, Houston innovators logged on to discuss technology and innovation that's taking off in town.

The second of the two days of programming focused on the development of the Houston innovation ecosystem — including how the city is factoring in diversity and inclusion into development — with interviews hosted by me, Natalie Harms, editor of InnovationMap. Missed out on the fun? Catch up with a few overheard moments from Houston House or stream the full interviews below.

"“We have to be true to ourselves of what works for Houston. Making sure the DEI is interwoven and in our DNA of our ecosystem so that we don’t make the same mistakes as other cities." — Ashley DeWalt, managing director of DivInc Houston

Video courtesy of the Greater Houston Partnership

Houston has an advantage in developing its innovation ecosystem because it can do so by learning from established ecosystems on the coasts. Locally, that means making diversity and inclusion a top priority. At a virtual SXSW Houston House panel, Ashley DeWalt, managing director of DivInc Houston, and Jan Odegard, interim executive director of The Ion, discuss the importance of prioritizing inclusion in developing Houston's innovation ecosystem. Click here to watch the full interview.

“This pandemic has really highlighted a lot of the health care disparities that are present within our systems. … Houston is in a unique position to address that.” — Fiona Mack, head of JLABS @ TMC

Video courtesy of the Greater Houston Partnership

The Texas Medical Center is the largest medical center in the world with over 10 million patients coming in annually — and JLABS @ TMC is right in the middle of that. With this access to patients and clinical trials, Houston has a lot of potential to attract new innovative companies solving the world's biggest health care problems. At a virtual SXSW Houston House HOU Talk, Fiona Mack, head of JLABS @TMC, discusses the momentum behind health tech innovation in Houston. Click here to watch the full interview.

“Whatever the training is, you have to actually create bias disruptors and points of friction and processes that change behavior. If we don’t have a way to implement what we learn, it doesn’t really change culture.” — LaTanya Flix, senior vice president at the GHP

Video courtesy of the Greater Houston Partnership

In light of the Black Lives Matter movement, corporations of all shapes and sizes were inspired to look inward to address inequity within their workforce — from training to shifts in workplace culture. At a virtual SXSW Houston House HOU Talk, LaTanya Flix, senior vice president of Diversity, Equity and Inclusion (DEI) at the Greater Houston Partnership, shares how she's on a mission to spread mindful DEI initiatives across all of the GHP's member organizations. Click here to watch the full interview.

“I see a world where I’m sitting in a boardroom, and I’m not the only woman anymore.” — Samantha Lewis, principal at Mercury Fund

Video courtesy of the Greater Houston Partnership

Women in venture capital are used to being the only women in the room and are fighting for that not to be the case for future generations. At a virtual SXSW Houston House panel, Sandy Guitar, managing director of the HX Venture Fund moderates a discussion with fellow women in VC, Paige Pitcher, director of innovation at Hines, and Samantha Lewis, principal at Mercury Fund. Click here to watch the full interview.

“There’s an incredible number of innovations that have popped up in Houston, but a lot of them have been centered around solving engineering-type problems at industrial scale — and that still exists, but doesn’t get as much coverage as consumer-facing technologies.” — Josh Pherigo, director of research and data analytics at GHP

Video courtesy of the Greater Houston Partnership

When tracking any sort of progress or growth, business look to their numbers and data. Houston's innovation system is no different. At a virtual SXSW Houston House HOU Talk, Josh Pherigo, director of research and data analytics at the Greater Houston Partnership, dives in deep with the facts and figures of Houston's burgeoning innovation ecosystem by following the venture dollars coming into local startups. Click here to watch the full interview.

“If you look at the density in Houston, being the energy capital of the United States, there are probably few places in the world where you can walk 15 minutes in either direction and talk to about 100 companies that would potentially be customers.” — Matthew Costello, CEO and co-founder of Voyager Portal

Video courtesy of the Greater Houston Partnership

A good startup idea comes from necessity and a way to apply technology to solve problems and shorten business delivery times, and the maritime shipping industry has a lot of opportunities for these types of innovations. At a virtual SXSW Houston House HOU Talk, Matthew Costello, CEO and co-founder of Voyager Portal, sets sail on a conversation about the maritime shipping industry — and how it was ripe with disruption. Click here to watch the full interview.

“You have institutions of exception in Houston where innovation flows from. The question isn’t that it’s not there, it’s how have we been tapping it.” — David Schubert, president of Magnolia Tejas Corp.

Video courtesy of the Greater Houston Partnership

Houston has a burgeoning life science innovation scene — but what's that next step for its development? At a virtual SXSW Houston House HOU Talk, David Schubert, president of Magnolia Tejas Corp. discusses the potential of Houston's world-class oncologists and biotech innovators have to make the city a hub for cancer innovation. Click here to watch the full interview.

The ultimate who's who of 2020 — favorite Houston Innovators Podcast guests of last year. Photos courtesy

Editor's Picks: Top 7 Houston innovation interviews of 2020

2020 in review

Editor's note: With 2020 in the rearview, InnovationMap is looking back on the top stories of the year. With over 60 episodes of the Houston Innovators Podcast and about half of those being recorded in 2020, here are the top episides from the year.

Chris Buckner, co-founder and CEO of Mainline

With sports went offline, esports startup Mainline saw an opportunity for growth during the COVID-19 outbreak. Photo courtesy of Mainline

What happened when collegiate sport stadiums shut down and seasons were postponed? People started to turn to esports to get their competitive fix. And Houston-based esports tournament software company Mainline saw a huge boost to business.

"Everyone is looking for how to get sports, or esports, in front of people because everyone is just missing [sports] so much," Chris Buckner, co-founder and CEO of Mainline, says in a June episode of the Houston Innovators Podcast. "We've been very fortunate to work in the industry we do."

On campuses this past spring, colleges are looking for a way to connect with and engage students, Buckner says. And, Mainline has even been able to attract interest on the professional level.

"Our June will pretty much be the best month of our company, and a lot of that is driven by the fact that everyone is looking for a digital solution rather than an in-person solution," Buckner says.

Read more and stream the podcast episode here.

Fiona Mack, head of JLABS @ TMC

Fiona Mack joined JLABS @ TMC as head of the incubator. Photo courtesy of JLABS

Last year, JLABS @ TMC — a local health tech startup incubator under the Johnson & Johnson arm — welcomed Fiona Mack as the new head of the program. On her plate was assessing the needs of the incubator's 49 member companies in the portfolio and understanding the needs of the Texas innovation ecosystem.

"As I learn more about the history of life science sector in Texas, over the past 20 years there has been an impetuous to build up this critical mass of companies here to really make it a strong hub that competes with the energy sector to make it a pillar of the economy here," Mack says in a November episode of the Houston Innovators Podcast.

One of the things that's top of mind for Mack is a focus on diversity — both from an entrepreneurship and a representation standpoint.

"From a research perspective, there's a strong effect of having a lack of diversity in a lot of the metrics we're looking at," she shares.

Read more and stream the podcast episode here.

Joe Alapat, CEO of Liongard

Joe Alapat is the CEO of Houston-based Liongard, which just raised a $17 million series B round. Courtesy of Liongard

Despite a pandemic that at least in some ways negatively affected venture capital investment, a Houston software startup managed to persevere with a $17 million series B. Liongard's CEO Joe Alapat, who co-founded the company with COO Vincent Tran in 2015, says in a May episode of the Houston Innovators Podcast that the round was the result of ongoing relationships with advisers and investors that meant a successful round — even in light of a pandemic.

In the episode, Alapat also shares his advice for Houston startups looking to tap into the Houston innovation ecosystem — something he's watched grow over the past five years. Now, he says, when it comes to new startups in Houston, "the waves are hitting the shore."

"Houston has always been an entrepreneurial city, and this is just that next stage," Alapat says on the episode. "For me, it's the technology side that excites me even more to see technology companies really succeeding."

Read more and stream the podcast episode here.

Megan Eddings and Amanda Cotler of Accel Lifestyle

Megan Eddings and Amanda Cotler of Accel Lifestyle joined the Houston Innovators Podcast to share how they made the pivot from making T-shirts to face masks. Photos courtesy

For years, Megan Eddings, founder and CEO of Accel Lifestyle, worked on perfecting the perfect antibacterial fabric for an anti-stink athletic clothing line, but it only took her a few weeks to pivot toward using the material to make masks.

On a May episode of the Houston Innovators Podcast, Eddings and Amanda Cotler, director of operations, shared the story of how this pivot came to be and how they saw the Center for Disease Control was recommending wearing bandanas and cloth when face masks weren't available, they had an epiphany.

"Megan and I read that and immediately hopped on a call with our team," Cotler says. "We had a realization with our antibacterial fabric that a face mask made from it would be so much cleaner."

Within 24 hours, the duo had a sample in their hands, and they had 14,000 yards of their Prema fabric being shipped from California to Houston, where they had managed to find 60 local sewers ready to start making the masks.

Now, with the Houston workforce making moves to return to the workplace, Eddings says she's seen an increased interest in corporations wanting custom masks with the company logo on it for their employees.

Read more and stream the podcast episode here.

Durg Kumar and Allen Bryant,  partners at Knightsgate Ventures

Houston-founded venture capital firm heads into second fund focused on social impactDurg Kumar (left) and Allen Bryant, partners at Knightsgate Ventures, join the Houston Innovators Podcast to discuss their second fund. Photos courtesy

Durg Kumar founded Knightsgate Ventures in order to find and fund startups with a social impact and a profitable business strategy. The Houston-based firm was founded in Houston and has since expanded to add a New York partner, Allen Bryant, to the operation. The duo joined the Houston Innovators Podcast in November.

"For a very long time, there was a perceived trade off between social returns and financial returns," Bryant says on this week's episode of the Houston Innovators Podcast. "What we are seeing now is that's really not the case. You actually have businesses that are bringing impactful change and those businesses are propelled by that."

The VC's first fund invested in six startups — including Houston-based Voyager — and is now heading into its second fund. Kumar says the first fund's success was in part due to his network. Now heading into the second go around, Knightsgate's network has grown with the addition of Bryant.

The end of the year, Kumar and Bryant were focused on helping their portfolio startups focus on the next year.

"Now's a good time to retrench and focus on building product," Kumar says, "so that in 2021 when travel restrictions ease, then you've got your refined product to go out and take it to the customers."

Read more and stream the podcast episode here.

Joy M. Hutton, local leader of the Grow with Google in Houston

Joy M. Hutton leads the Grow with Google in Houston. Photo courtesy of Google

In November, when Google announced it was expanding its Grow with Google Digital Coach program to Houston, Joy M. Hutton was named the local leader. The entrepreneur and business consultant is hoping to help provide important business resources to entrepreneurs just like herself.

"In Houston, you have a lot of different resources that weren't available to startups before just within the past few years, and I think that's huge," Hutton says in a December episode of the Houston Innovators Podcast. "Being more inclusive with people who need the resources who haven't traditionally had access to those resources is a big initiative. I personally am proud to be a part of that."

Hutton specifically calls out resources like MassChallenge and Founder's Institute — both of which she serves as a mentor for — as well as DivInc, gBeta, and of course the Grow with Google program. To get involved, Houston entrepreneurs can head online to learn more and keep an eye out for monthly classes online — and hopefully, in the future, in person events as well.

Read more and stream the podcast episode here.

Kyle Judah, executive director of Rice University's Liu Idea Lab for Innovation and Entrepreneurship

Kyle Judah joins the Houston Innovators Podcast to discuss his new role. Photo courtesy of Lilie

When Kyle Judah accepted his position as executive director at Rice University's Liu Idea Lab for Innovation & Entrepreneurship, he had spent less than 48 hours in the city of Houston. In fact, his first two months in the role have been spent completely remote and out of town.

Still, his limited in-person interaction with the city and with Rice made an impact.

"One of the things I found so exciting about what's going on in Houston right now that, quite frankly, was incredibly attractive about the opportunity to come and join Lilie and Rice was that Houston has these big pillar companies in energy and health care and all these critical areas that the world, the economy, and the society needs," Judah says in a September episode of the Houston Innovators Podcast. "That's all in Houston right now."

Judah and Lilie's goal is to help identify the innovation happening on campus at Rice and bring it to the world. And, he says, Rice as a whole has a huge place in the greater Houston innovation ecosystem. The challenge is identifying what industries Houston and Rice have an opportunity to disrupt.

"We can't just copy and paste what works for the Bay Area or what works for Boston," he says. "We have to figure out what is going to be the authentic right sort of centers of excellence for Rice and for Houston — areas like energy, health care, space. It just so happens that these areas that Houston and Rice have historically done better at than anyone else — those happen to be the most grand challenges for all of humanity."

Read more and stream the podcast episode here.

This week's innovators to know roundup includes Fiona Mack of JLABS, Grace Rodriguez of Impact Hub Houston, and Emily Cisek of The Postage. Photos courtesy

3 female Houston innovators to know this week

who's who

Editor's note: In today's Monday roundup of Houston innovators, I'm introducing you to three female innovators across industries — from life science to impact innovation.

Fiona Mack, head of JLABS @ TMC

Fiona Mack has joined JLABS @ TMC as head of the incubator. She shares her vision for the lab on this week's episode of the Houston Innovators Podcast. Photo courtesy of JLABS

Fiona Mack is among the latest additions to the Houston innovation ecosystem, as she joined JLABS @ TMC just a few months ago. On her plate right now is assessing the needs of the incubator's 49 member companies in the portfolio and understanding the needs of the Texas innovation ecosystem.

"As I learn more about the history of life science sector in Texas, over the past 20 years there has been an impetuous to build up this critical mass of companies here to really make it a strong hub that competes with the energy sector to make it a pillar of the economy here," Mack says. Read more and stream the podcast interview.

Grace Rodriguez, executive director and CEO of Impact Hub Houston

Grace Rodriguez and her team at Impact Hub Houston is in for a busy week. Courtesy of Impact Hub Houston

Grace Rodriguez has a marathon of a week ahead of her — but it's an exciting one. The fourth annual Houston Innovation Summit is going on now, and she's really passionate about the theme.

"The focus on education and policy is really interesting to me — it's not just about tech and business anymore," Rodriguez says. "It's really about how we are supporting businesses in the face of the pandemic, climate change crises — floods, fires, hurricanes — the entire world is being affected by these crises. ... [We need to focus on] how we are making sure that people are aware of everything that's happening and how we can innovate solutions." Read more about the latest from Impact Hub and what THIS events not to miss.

Emily Cisek, founder of The Postage

The Postage is a new company that uses technology to help ease the experience of afterlife responsibilities for family members. Photo courtesy of The Postage

Three years ago, Emily Cisek was struck with immense grief when she lost three family members back to back. She says she learned first-hand how arduous the process of wrapping up someone's life is and how it can take away from the grieving process.

Cisek's grief planted a seed and she has the idea for The Postage, a digital platform that helps collect information and digital assets in one place to ease with affair planning.

"I think the way The Postage has [made planning more available] it's provided a price point, an understanding and steps involved that are more easily accessible; no matter what age group, what race, what your background is, your religion, anything like that, you're able to sign up," says Cisek. Read more.

Fiona Mack has joined JLABS @ TMC as head of the incubator. She shares her vision for the lab on this week's episode of the Houston Innovators Podcast. Photo courtesy of JLABS

New Houston life science incubator leader is focusing on inclusion in health innovation

houston innovators podcast episode 57

By now, Fiona Mack has worked in a few sectors and stages of health innovation — mostly within oncology and biopharmaceuticals. However, since being named the head of JLABS @ TMC a few months ago, she's jumped headfirst into Houston life science startup incubation.

"I've been kind of drinking from the fire hose. I've really tried to understand the J&J organization, which is quite global in its scope across multiple sector areas," Mack shares on this week's episode of the Houston Innovators Podcast. "On a regional level, I've been focusing on understanding my portfolio."

On her plate right now is assessing the needs of the incubator's 49 member companies in the portfolio. Additionally, she's working on recognizing any gaps in leadership — the position has been vacant around a year and a half since the former head, Tom Luby, transitioned to leading the TMC Innovation Institute — and understanding the needs of the Texas innovation ecosystem.

"As I learn more about the history of life science sector in Texas, over the past 20 years there has been an impetuous to build up this critical mass of companies here to really make it a strong hub that competes with the energy sector to make it a pillar of the economy here," Mack says.

One of the things that's top of mind for Mack is a focus on diversity — both from an entrepreneurship and a representation standpoint.

"From a research perspective, there's a strong effect of having a lack of diversity in a lot of the metrics we're looking at," she shares.

Mack says innovation is driven by data, and data, especially when your using that information to treat a diverse group of people, needs to be representative. And Houston is a great place to make that happen.

"What information are we putting into those datasets? If it only represents a homogenous population, it certainly can't be applied to the real world," Mack says. "There's a need to be much more inclusive into what we're analyzing. Houston, in terms of its population, is highly diverse — and we can speak about it ethnically and from an economic standpoint."

Mack shares more of her big picture vision for JLABS @ TMC on the episode, as well as what her early impressions of Houston have been so far. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


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Texas still ranks as No. 1 in U.S. for inbound moves, but growth dips

by the numbers

Texas continues to be the country’s No. 1 magnet for newcomers from other states, giving a boost to the state’s economy. However, Texas’ appeal weakened in 2024 compared with the previous year, due in large part to spiking home prices.

An analysis of U.S. Census Bureau data by self-storage platform StorageCafe shows Texas saw net interstate migration of 76,000 people in 2024. Texas’ net interstate migration dropped nearly 50 percent from 2023, according to the analysis. Net migration refers to the number of incoming residents minus the number of outgoing residents.

California remained the top source of newcomers for Texas, sending nearly 77,000 residents to the Lone Star State in 2024, the analysis says. Florida ranked second, followed by New York, Colorado and Illinois.

“These trends reveal Texas’ continued pull from both high-cost coastal markets and other large Sun Belt states, resulting in a mix of affordability-driven and job-driven relocation,” StorageCafe says.

Putting a damper on the influx of new residents: a roughly 124 percent surge in Texas home prices over the past decade, according to StorageCafe.

“While the state remains significantly more affordable than California, its top feeder state, the once-wide pricing gap has narrowed,” says StorageCafe. “For many movers, Texas is still a relative bargain, but no longer an undisputed one.”

Nonetheless, Texas keeps attracting young, highly educated people, which bodes well for the state’s long-term economic outlook, StorageCafe says. More than half of new arrivals to Texas in 2024 held at least a bachelor’s degree, and the age of newcomers averaged 32.

Where are most of these young, highly educated newcomers settling?

Lloyd Potter, former Texas state demographer, tells StorageCafe that population growth in Texas is happening most rapidly in suburban “ring counties” at the expense of slowing growth in urban cores. Ring counties are on the outskirts of major metro areas.

“Many people are moving from urban cores to suburban rings seeking lower costs, newer housing, better schools, and more space,” Potter says. “Typically, a move to a suburban county will be within commuting or hybrid‑commuting distance of major metro economies.”

Artemis II makes historic call to space station with help from Houston Mission Control

History in the making

Still aglow from their triumphant lunar flyby, the Artemis II astronauts made more history Tuesday, April 7: calling their friends aboard the International Space Station hundreds of thousands of miles away as they headed home from the moon.

It was the first moonship-to-spaceship radio linkup ever. NASA's Apollo crews had no off-the-planet company back in the 1960s and 1970s, the last time humanity set sail for deep space.

"We have been waiting for this like you can’t imagine,” Artemis II commander Reid Wiseman called out.

For Christina Koch on Artemis II and Jessica Meir aboard the space station, it marked a joyous space reunion despite being 230,000 miles (370,000 kilometers) apart. The two teamed up for the world's first all-female spacewalk in 2019 outside the orbiting lab.

Koch told her “astro-sister” that she'd hoped to meet up with her again in space “but I never thought it would be like this — it's amazing.”

“I'm so happy that we are back in space together,” Meir replied, “even if we are a few miles apart.”

Houston's Mission Control arranged the cosmic chitchat between the four lunar travelers and the space station's three NASA and one French residents.

Koch described being awe-struck by not just the beauty of Earth, “but how much blackness there was around it.”

“It just made it even more special. It truly emphasized how alike we are, how the same thing keeps every single person on planet Earth alive,” she told the space station crew. “The specialness and preciousness of that really is emphasized” when viewing the home planet from the moon.

By late Tuesday afternoon, the Artemis II astronauts had beamed back more than 50 gigabytes' worth of pictures and other data from the previous day's lunar rendezvous, which set a new distance record for humanity. The highlight: an Earthset photo reminiscent of Apollo 8's Earthrise shot from 1968.

"While they are inspirational and, I think, allow all of us to really feel a little bit of what they were feeling, there's also a lot of science hidden inside of those images," said Mission Control's lead lunar scientist Kelsey Young. “The conversations and the science lessons learned are just beginning."

During a debriefing with Young, the astronauts recounted how they spotted a cascade of pinpricks of light on the lunar surface from impacting cosmic debris. The flashes lasted mere milliseconds and coincided by chance with Monday evening's total solar eclipse.

Young said it was too soon to know whether the crew witnessed an actual meteor shower or more random, run-of-the-mill micrometeoroid hits. Either way, there were “audible screams of delight” in the science operations center, she said.

Koch described being awe-struck by not just the beauty of Earth, “but how much blackness there was around it.”

“It just made it even more special. It truly emphasized how alike we are, how the same thing keeps every single person on planet Earth alive,” she told the space station crew. “The specialness and preciousness of that really is emphasized” when viewing the home planet from the moon.

The first lunar explorers since Apollo 17 in 1972, Wiseman and his crew are aiming for a splashdown off the San Diego coast on Friday to wrap up the nearly 10-day test flight. The recovery ship USS John P. Murtha left port Tuesday for the target zone.

It sets the stage for next year's Artemis III, a lunar lander docking demo in orbit around Earth. Artemis IV will follow in 2028 with two astronauts attempting to land near the lunar south pole.

As for the Orion capsule’s pesky potty, Mission Control assured the astronauts that no maintenance was required Tuesday. The toilet has been on-and-off limits to the crew ever since last week’s launch, prompting them to rely on a backup bag-and-funnel system for urinating.

NASA Administrator Jared Isaacman told the crew following the lunar flyby Monday night: “We definitely have to fix some of the plumbing” ahead of the next Artemis mission. Engineers suspect a clogged filter in the overboard flushing system.

Aside from the toilet and other relatively minor matters, the mission has gone well, Isaacman noted at a news conference Tuesday, “but I'll breathe easier when we get through reentry and everybody's under chutes and in the water.”

AI-powered Houston startup helps restaurants boost customer loyalty

order up

It’s no secret that restaurant trends move fast and margins run thin. And with the proliferation of platforms like Uber Eats, DoorDash and Easy Cater, customer loyalty is fleeting.

The solution?

How about an AI-powered restaurant technology platform that helps restaurant brands cut back on third-party platforms in favor of driving direct discovery, conversion and loyalty?

Enter Saivory. Founded in 2025 by Stephen Klein, a software investor, and Fajita Pete’s restaurateur Hugh Guill, the Houston-based startup aims to help eateries better understand and activate guest behavior across digital channels as AI increasingly reshapes how consumers discover and engage with brands.

In less than a year, Saivory has partnered with Shipley Do-Nuts and Fajita Pete’s to bring AI-powered ordering to life.

“With Saivory, we were able to answer the question of, ‘what if the ordering process could be reduced to a single step, where customers simply tell us what they want and AI takes care of the rest?’” Klein tells InnovationMap.

The Houston-based startup made such an immediate impact that it was selected as a semi-finalist during Start-Up Alley at MURTEC, the restaurant industry’s leading technology conference, which took place last month in Las Vegas.

“Houston is a great hub for technology innovation, and we were proud to represent the city at MURTEC this year,” says Klein. “We didn’t win, but we were able to talk about some of the work that we have existing in the market for clients right now and a little bit about what we’re working on in the future.”

In the current restaurant technology ecosystem, the third-party aggregators own the customer attention that brings volume to restaurants, while also taking big commissions and having control over the end relationships with the customer.

That can often make it difficult for restaurants to grow loyalty and repeat business from customers. Saivory aims to level the playing field for restaurants, helping them stay more connected to their customers.

Take Saivory’s recent application with Shipley’s Do-Nuts, for example.

Saivory powered the donut giant’s AI-ordering and launched Shipley's website and mobile app to support its over 300 locations in Texas alone.

Shipley’s new AI-powered assistant helps users create personalized order recommendations based on individual or group preferences. And unlike standard chatbox features, the new assistant makes custom recommendations based on multiple customer factors, including budgetary habits, individual flavor preferences and order size. It can also be used for large catering orders.

“They're seeing more traffic to the site and they're seeing when customers use our AI-enabled flows,” Klein says. “And they're seeing higher basket sizes, bigger tickets, by about 25 percent.”

Klein says Saivory’s technology helps strengthen first-party digital relationships, reduce friction and cart abandonment, improve average order value, and delivers personalized, efficient experiences.

“It’s a win-win: the customer gets the right order quickly, while the restaurant gets a bigger margin,” he adds.

Additionally, the technology makes it easier for restaurants to share rewards, loyalty and discounts, ultimately growing more direct traffic and making restaurants less reliant on third-party delivery apps.

Next up for Saivory is adding new components to its platform to enhance the relationship between restaurant and customer, as well as technology around making it easier for restaurants to get found on Google.

“A lot of people are still searching for the best donuts near me,” Klein says. “Or what’s the best Mexican food near me? Customers will increasingly move to AI, where they’re going to ask where they should eat dinner and expect it to just order them dinner. They will eventually expect the technology to know how to do that. So that’s what we’re driving at.”

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