5 most popular innovation stories in Houston this week

Now trending

Life Time announcing its new downtown coworking space and fitness center was among this week's top stories. Courtesy of Life Time

Editor's note: This week's trending news has a theme — dreaming big. From new hires across the ecosystem to futuristic design projects, the top stories on InnovationMap are pretty exciting.

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Local architects design projects to impact Houston's future

Gensler's ByDesign group dreams up innovative real estate projects that solve Houston problems — like a tower that can absorb and filter water from a flood. Courtesy of Gensler

When the working day is done, there's a group of young architects who, rather than closing out their design programs and hitting happy hour, continue to design and innovate projects. Only, they aren't doing it for clients or money. Gensler's ByDesign organization, which was created about four years ago, is an extracurricular of sorts for Houston's young architects. The projects are created and presented by the architects and are impact-focused, seeking to provide a solution of a problem in Houston. Click here to read the full story.

3 Houston innovators to know who are starting new roles

TMC Innovation, Station Houston, and FanReact all made executive hires last week. Courtesy photos

It's been a busy week for Houston innovators. TMC Innovation Institute hired its new director, and Station Houston created a new director position — and filled it too. Plus, FanReact decided to divide and conquer its esports business, which meant a new executive hire. Click here to read the full story.

Company closes $1M round, new nonprofit startup hub launches, and more Houston innovation news

From closing a million-dollar raise to being tapped by Google to serve on a council, Houston entrepreneurs have been busy. Courtesy of Security Gate

Wrapping up March, there's been a lot of innovator and startup news that's slipped through the cracks. From funds closing and incubator applications opening, here's all the news bits you need to know. Click here to read the full story.

4 fitness-focused Houston startups changing the industry

From what you wear to where you go, here are some Houston fitness startups changing the game. Courtesy of Accel Lifestyle

Houston has developed into a city full of boutique fitness studios and updated parks, and now the city is seeing fitness startups popping up as well. From creating a smell-free fabric to engaging NASA technology into training, these Houston fitness startups are working out innovative ideas into the exercise industry. Click here to read the full story.

Life Time to open a new coworking space and fitness club in downtown Houston

GreenStreet will soon have coworking space and a gym from Life Time. Courtesy of Midway Cos.

Life Time has announced its second Houston location of its coworking concept, Life Time Work, before it's even opened the first. Life Time will open an athletic club and coworking space in GreenStreet in downtown Houston. Houston's first Life Time Work in CITYCENTRE, which was announced last year, is expected to open in May. Click here to read the full story.

From what you wear to where you go, here are some Houston fitness startups changing the game. Courtesy of Accel Lifestyle

4 fitness-focused Houston startups changing the industry

Business exercise

Accel Lifestyle

Courtesy of Accel Lifestyle

Megan Eddings tried everything to get the stink out of her husband's workout clothes, but nothing worked completely. With her background in chemistry, she knew there was something she could do to create a fabric that didn't hold on to the bacteria that built up in normal fabrics. So, she got to work. Now, years later, she's finally perfected her product and is ready to launch by summer.

"I never thought it would take this so long to make a T-shirt," Eddings says. "But, if you do it right and in an ethical way, it just takes a little longer."

Eddings says she'll have six different styles of men's and women's shirts to start, and they will be available on the Accel website, which recently got a facelift. Read more about Accel's journey here.

Kanthaka

Courtesy of Kanthaka

Finding a quality personal training session that fits your schedule and location hasn't really been done before Houston-based Kanthaka launched in 2017. Founder Sylvia Kampshoff wanted something that allowed her to exercise with someone on her own schedule, and with people who valued customer service.

The app uses location technology similar to that of ride sharing apps to allow users to book training sessions with certified personal trainers, all of whom are heavily vetted and background checked by Kampshoff and her team.

"Many trainers at gyms or who work privately aren't certified," she says. "And that was important to me, that we have professionals who understand training and the body. And making sure our clients felt safe was a huge priority for me. We interview every trainer personally to ensure they not only meet our standards but also share our goals."

Since launch, Kanthaka has expanded to Austin and is expanding to San Antonio in April and Atlanta in May. The company has secured angel investment and has seen a month over month growth of 10 to 50 percent since the end of 2018. Read more about Kanthaka here.

Muvve

Courtesy of Muvve

What would you get if you crossed a dating app with an event planner focused on creating friendships around fitness? Houston-based Muvve. The app, which was created by Avi Ravishankar and Julian Se, came from the idea that working out, training for a marathon, or just staying active is way better with a buddy.

"Intrinsic motivation is hard to find, especially in individual sports, like running, cycling, or yoga," Ravishankar says. "Whereas, in team sports, like basketball or volleyball, you have the team to train with and motivate you."

The app, which launched in May of 2018, acts like a network for fitness lovers — just like a dating app would connect potential romantic partners. Dating apps, actually, were a big influence on Ravishankar, he says.

"I fell in love with dating apps. It was this mind-blowing idea for me of how many people you can connect with — even if it's not for dating," he says. "The amount of people I have met just through technology always blows my mind. There's so much power in it."

Ravishankar plans on growing the app's user base to 10,000 users by summer. Read more about Muvve here.

Sutaria Training & Fitness

Blake Hobson/ST&F

Sutaria Training & Fitness LLC, a Houston-based personal training company, has a new partnership with NASA that aims to provide exclusive access to astronaut training equipment to clients.

Jay Sutaria, founder and lead trainer, says that the equipment at NASA, called the force plate, shows how much power a client's body is producing in specific areas and how that power drops over time. The data produced by these machines can help trainers customize and tweak workouts for each client to take training a step further.

Sutaria and his partners at NASA recently tested the equipment with the Chinese olympic boxing team to see how it can be applied to workouts at NASA's location in Clear Lake.

"It's exclusive access to the equipment that is not available openly in Houston," says Sutaria. "NASA is a reference for us to become better trainers." Click here to read more about ST&F.

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Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

$1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
$922 million for the University of Houston System
$167 million for Texas Southern University
$10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
Created the Lake Houston Dredging and Maintenance District
Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.

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