Global space startup and innovation connector opens Houston branch

Space city win

Australia-based Moonshot has opened a Houston chapter. Miriam Espacio / Pexels

It's almost an understatement to say that Houston's space economy is taking off like a rocket.

On May 28, four companies in the Houston area — Axiom Space Inc., Boeing Co., KBRwyle, and NanoRacks LLC — were tasked with helping chart NASA's course in the space economy, whose global value is projected to climb as high as $3 trillion by 2040. Three days later, Houston-based Intuitive Machines LLC was awarded a $77.2 million contract to send as many as five NASA payloads to the moon.

And a month later, on June 26, officials broke ground on the first phase of Houston Spaceport, a 450-acre project at Ellington Airport that will serve as a sort of control center for aerospace research and manufacturing, and commercial space operations.

Then, on July 19 — a day ahead of the 50th anniversary of Apollo 11 man-on-the-moon mission — Australia-based startup Moonshot Space Co. launched a chapter in Houston to help foster the region's multibillion-dollar space economy. Through its programming, which will kick off this fall, Moonshot seeks to corral entrepreneurs, students, job seekers, business executives, investors, university researchers, government officials, and others in an effort to nurture and promote Houston's space economy.

Troy McCann, founder and CEO of Moonshot, believes Houston — home to NASA's Johnson Space Center — can emerge as the epicenter of the global space economy.

"You'd have to have been living under a rock for the past 50 years not to be aware of Houston's stellar aerospace ecosystem," McCann says. "It's got both the historical credibility and a suite of … successful commercial space ventures based there."

"We want to help fine-tune Houston's space economy by providing a proven framework to elevate people and their ideas into successful teams and scalable businesses," McCann adds, "and to create the industries of the future and solve humanity's greatest challenges."

The Houston chapter, a nonprofit venture, is Moonshot's first in the U.S. and second outside Australia. Nathan Johnson, a Houston attorney who specializes in space law and business development, has been tapped to direct it.

"We're in the process of starting chapters across the globe because we believe that the next Nikola Tesla or Marie Curie is out there somewhere, but they don't have access to the resources they need to change the world for the better," McCann says. "Today, the average person has the ability to start a commercial space program for less than the cost of a fast-food franchise."

Johnson says Houston's prominence as NASA's hub for human spaceflight, its status as the "Energy Capital of the World," and the presence of the Texas Medical Center combine to make Space City a potent force in the space economy.

"My hope is to see Houston continue to lead in space and become a hub for the next wave of space commercialization," Johnson says. "We have a wide breadth of industries, and I would like to see that terrestrial expertise extend to new market applications in space."

If Houston does evolve into a nucleus for the global space economy, it stands to reap sky-high financial rewards. Various analysts forecast the global space economy will soar to between $1 trillion and $3 trillion by 2040, up from an estimated $415 billion in 2018.

"Space is and will be a global endeavor, depending on a strong economy, smart industries, and a talented workforce," Johnson says. "Houston already has all of those things, continues to actively develop them at all levels of the community, and does so in a way that reflects the world's population."

Mario Diaz, CEO of the Houston Airport System addresses the crowd gathered to celebrate the Apollo 11 anniversary this weekend. Natalie Harms/InnovationMap

Overheard: Aerospace and airport VIPs commemorate Space City Month at IAH

Out of this world

Houston, we have liftoff of a space-filled weekend. Saturday, July 20, marks the 50th anniversary of Apollo 11 touching down on the moon, and that calls for a celebration, as well as a commemoration.

Houston First, Space Center Houston, NASA, and United Airlines teamed up to host an international delegation at George Bush Intercontinental Airport in Terminal C on July 17. Various space or Space City VIPs took the stage to discuss their memories of the lunar landing and the role Houston played in the monumental event.

“Our hope is to be an airport system that reflects Houston’s role as a leader on the global stage and to have our city standing as truly international business and cultural center. With both Bush and Hobby airports having earned four-star ratings, we are built to meet those expectations.”

— Mario Diaz, executive director at Houston Airport System. Bush Intercontinental Airport is also celebrating its 50th anniversary since opening in 1969.

“It is the innovative spirit of the people of this city that help give the world our new perspective. We are all neighbors, and we must all face the future as one. How wonderful that understanding is now with Houston having become the nation’s most diverse city in the country with one in four Houstonians being foreign born.”

— Houston Mayor Sylvester Turner, referencing a ranking released earlier this year.

“This week, we are celebrating this anniversary and time when we did so much more than we thought we could. … [the Apollo mission] was an inspiration to us then, and I think continues to be an inspiration to all of us even now.”

— Peggy Whitson, former NASA astronaut who holds the record for the United States for her 665 days in space.

“Houston is the Space City, because the Johnson Space Center is the home of human space flight. As you know, ‘Houston’ was the very first word spoken from the surface of the moon. And, it wasn’t a fluke. They knew who they needed to talk to, and it was Houston.”

— Mark Geyer, director of NASA's Johnson Space Center.

“In roughly three years, we will have astronauts back in the region of the moon — this time women and men. And soon after that, back onto the surface of the moon again in our mission called Artemis.”

— Geyer continues to say of NASA's lunar exploration plans.

“Just a few weeks ago, [Space Center Houston] inaugurated the completely restored mission control operations room from the Apollo era. We’ve done a restoration and taken it back to the 1960s, and it appears as if the flight controllers just got up to take a break.”

— William Harris, CEO of Space Center Houston. The organization is NASA's official tourism arm and houses 250,000 square feet of indoor and outdoor exhibition space.

David Alexander of the Rice University Space Institute says Houston's past accomplishments in space aren't all the Space City has to offer. Photo courtesy of Rice University

Rice University's Space Institute director on the future of exploration, development, and the role Houston will play in space

Featured Innovator

While the city is celebrating the 50th anniversary of the Apollo mission that got man to the moon, this month should also be about looking forward to the Space City's future.

From commercial space travel momentum to upcoming governmental projects, there's a lot in the works for space, and Houston will play a big role in both sides of the equation, says David Alexander, director of the Rice University Space Institute.

"In Houston, we tend to think of space as a destination, but it really is a resource," he says. "And we need to be thinking about it as a resource."

New, and increasingly more accessible technologies are changing the landscape — especially for universities. Smaller satellite devices, called CubeSacs, are so easy to build and launch into space that students are able to it themselves, Alexander says, and they are. These projects across the country are collecting new data on a massive level.

"Students these days really want to solve meaningful problems rather than just academic problems, and space is way of giving them access to what information and data that can help them with that," Alexander says.

Alexander shared his thoughts and professional opinion on some of the exciting advancements the space industry has on its radar — and where Houston comes into play for these initiatives.

InnovationMap: What got you really interested in space exploration?

David Alexander: I was always interested in science, but one of the things got really interested in the human aspect of space was an event at the Rice Baker Institute a few years ago, shortly after the cancellation of the shuttle program. It was just a great discussion about the space in general, but what kind of hit me hard was the fact that a lot of history — we're talking about 50 years in space since the Apollo mission — has influenced the whole world. Modern human history has been hugely impacted by the presence of space, and a lot of that happened in Houston. And, some of the people who've made it happen are still around, and that day at the Baker Institute, some of them were there. So, that hit home for me.

IM: What are some of the focuses of the Rice Space Institute?

DA: We've got the outreach part, then we have the the science, the research, and then student activities and the connection to NASA that we have.

We have a professional master's program for students who are not particularly interested in research, but what they want to do is combine management and business training with technical training in science and engineering related to space. We've been building that program all for over the last six years or so. We also have this fairly popular public lectures series that we've been running since January of 2011.

One of the prime reasons for institutes at Rice, which are small entities, is to bring faculty from different disciplines together. And so that's been our primary effort when it comes to research. We'll try and get some of the bioengineers, for instance, working with NASA on the human side, and get some of the engineers working with NASA on things like sensor wireless technologies.

IM: What does the future of space exploration look like to you?

DA: I think one of the things that we're seen this helping drive that difference between now and then is the growth in the private and commercial enterprises in space. I think that what we're finding is that space is becoming more accessible. The actual cost of getting to space is radically coming down, and the kind of resources that we can put in space and the capability of these resources is changing.

IM: Do you think there's been a resurgence of interest in space lately?

DA: NASA made space kind of look routine, which is good because you want astronauts to be safe and you want your hardware to survive. So, it became less exciting. However, within the government side of things, that has been a huge steady progress. You can follow the path from the technology development all the way through to today. But I think from the general public's perception, people like Elon Musk, even though he has some ambitious ideas, has seen successes with reusable rockets with these landings. And people like Jeff Bezos, who are also developing their own rockets and their own plans for space, have kind of opened people's eyes again a little bit. I think they have added a bit of star power, and they have shown an excitement for space that's infectious.

IM: What does the celebration of the 50th anniversary of the Apollo 11 mission mean to the city of Houston?

DA: There's a balance that we have to find between looking too much in the past — you don't want to see your successes in the rearview. I think we should rightly be proud of the Apollo history and what it did for the region. The history part is really important, and, in my opinion, the biggest thing that came out of Apollo is the fact that so many young people got interested in science, technology, engineering, and math. I firmly believe that created the means by which the U.S. economy drove the world.

IM: What's Houston's role in the future of space exploration?

DA: On the space exploration side, NASA has announced that we're going to go back to the moon by 2024. Now, that's a huge challenge. The NASA administrator, Jim Bridenstine, who's a Rice graduate, is aware of those challenges. Whether it's 2024 or if we have to wait until 2028, a lot of that work is going to be driven by what's being done in Houston, particularly the Johnson Space Center. There's a big rocket that they're developing, as well as the Orion capsule, Houston has a big role in those.

On the commercial side, there's the Houston Spaceport, which was the 10th licensed commercially licensed spaceport in the United States. There's now 12 within the United States, but Houston's spaceport is the only one located in a large city. There's a great company out there called Intuitive Machines, and they just got one of the lunar landing contracts. So, sometime between now and 2021, there may actually be a piece of hardware land on the moon that was built here in Houston.

IM: What should the Houston innovation ecosystem be focused on?

DA: The pieces are all there. We just need to work together to get them working coherently. If you get someone who understands space data talking to one of these companies who are trying to monitor flooding, for example, then both of those groups will grow together. We need to start bringing them together.

------

Portions of this interview have been edited.

Houston is celebrating 50 years since the Apollo moon landing. Here are somethings you can expect to see in Houston during Space City Month. Photo via NASA.gov

Here's what you should look out for in Houston during Space City Month

The eagle has landed

Fifty years ago, NASA sent a crew of astronauts to the moon and back while a team controlled the mission from the Johnson Space Center in Houston.

In honor of this history-making experience, the Space City is playing host to Space City Month this July, and it's a time to recognize the science and sacrifice it took to put man on the moon, as well as look forward to the future of NASA and space exploration.

Restored Apollo 11 mission control center

Photo via NASA.gov

Ever wonder what it was like to be in the room where it happened — where Neil Armstrong radioed in to give his famous, "One small step for man, one giant leap for mankind" statement? Now you can.

Space Center Houston has restored the mission control center where dozens of professionals kept watch and records over the astronauts making their harrowing journey. The exhibit just opened, and visitors can sign up for free tickets.

The restoration has been years in the making. Retired mission control experts contributed to the exhibit and the efforts were even funded by a Kickstarter campaign that raised over $500,000.

Special NASA programming

The video and audio coverage were an incredible component for the Apollo missions to deliver to an earthly audience. Now, celebrating 50 years, NASA's bringing back the special programming.

From noon to 2 pm on July 19, the organization will broadcast live from NASA's newly-restored Apollo mission control room at Johnson Space Center in Houston, along with a couple other historic locations like the Kennedy Space Center in Florida, the Marshall Space Flight Center in Huntsville, Alabama, the Smithsonian National Air, and the Space Museum in Washington.

Watch the show on something that wasn't available in 1969: The internet. More specifically, find the stream on the NASA Live page.

InnovationMap interviews with space innovators

Tim Kopra

Tim Kopra spent over 244 days in space, and now he's using his tech background to invest in emerging energy companies. Courtesy of Tim Kopra

Much like we did for Pride Month, our Featured Innovator section — where we run weekly innovator interviews — will be taken over by a special series. Four different interviews with four different space innovators will be published on Wednesdays for the rest of the month.

Can't wait until Wednesday? Check out this interview we did with an astronaut turned venture capital investor, Tim Kopra. He spent a career total of 244 days in space before re-entering earth's orbit and civilian life. As different as his career is now compared to life in space, he actually sees a similarity.

"On face value, it may sound like an odd match, taking someone with a tech and operational background and putting them in venture, but quite frankly it feels very familiar to me because my career has really been focused on working on complex technology and operations with very small teams," Kopra tells InnovationMap in the article. "It's not just a theoretical understanding of the technology, but understanding how to use the technology and how it works."

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

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