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Rice University's Space Institute director on the future of exploration, development, and the role Houston will play in space

David Alexander of the Rice University Space Institute says Houston's past accomplishments in space aren't all the Space City has to offer. Photo courtesy of Rice University

While the city is celebrating the 50th anniversary of the Apollo mission that got man to the moon, this month should also be about looking forward to the Space City's future.

From commercial space travel momentum to upcoming governmental projects, there's a lot in the works for space, and Houston will play a big role in both sides of the equation, says David Alexander, director of the Rice University Space Institute.

"In Houston, we tend to think of space as a destination, but it really is a resource," he says. "And we need to be thinking about it as a resource."

New, and increasingly more accessible technologies are changing the landscape — especially for universities. Smaller satellite devices, called CubeSacs, are so easy to build and launch into space that students are able to it themselves, Alexander says, and they are. These projects across the country are collecting new data on a massive level.

"Students these days really want to solve meaningful problems rather than just academic problems, and space is way of giving them access to what information and data that can help them with that," Alexander says.

Alexander shared his thoughts and professional opinion on some of the exciting advancements the space industry has on its radar — and where Houston comes into play for these initiatives.

InnovationMap: What got you really interested in space exploration?

David Alexander: I was always interested in science, but one of the things got really interested in the human aspect of space was an event at the Rice Baker Institute a few years ago, shortly after the cancellation of the shuttle program. It was just a great discussion about the space in general, but what kind of hit me hard was the fact that a lot of history — we're talking about 50 years in space since the Apollo mission — has influenced the whole world. Modern human history has been hugely impacted by the presence of space, and a lot of that happened in Houston. And, some of the people who've made it happen are still around, and that day at the Baker Institute, some of them were there. So, that hit home for me.

IM: What are some of the focuses of the Rice Space Institute?

DA: We've got the outreach part, then we have the the science, the research, and then student activities and the connection to NASA that we have.

We have a professional master's program for students who are not particularly interested in research, but what they want to do is combine management and business training with technical training in science and engineering related to space. We've been building that program all for over the last six years or so. We also have this fairly popular public lectures series that we've been running since January of 2011.

One of the prime reasons for institutes at Rice, which are small entities, is to bring faculty from different disciplines together. And so that's been our primary effort when it comes to research. We'll try and get some of the bioengineers, for instance, working with NASA on the human side, and get some of the engineers working with NASA on things like sensor wireless technologies.

IM: What does the future of space exploration look like to you?

DA: I think one of the things that we're seen this helping drive that difference between now and then is the growth in the private and commercial enterprises in space. I think that what we're finding is that space is becoming more accessible. The actual cost of getting to space is radically coming down, and the kind of resources that we can put in space and the capability of these resources is changing.

IM: Do you think there's been a resurgence of interest in space lately?

DA: NASA made space kind of look routine, which is good because you want astronauts to be safe and you want your hardware to survive. So, it became less exciting. However, within the government side of things, that has been a huge steady progress. You can follow the path from the technology development all the way through to today. But I think from the general public's perception, people like Elon Musk, even though he has some ambitious ideas, has seen successes with reusable rockets with these landings. And people like Jeff Bezos, who are also developing their own rockets and their own plans for space, have kind of opened people's eyes again a little bit. I think they have added a bit of star power, and they have shown an excitement for space that's infectious.

IM: What does the celebration of the 50th anniversary of the Apollo 11 mission mean to the city of Houston?

DA: There's a balance that we have to find between looking too much in the past — you don't want to see your successes in the rearview. I think we should rightly be proud of the Apollo history and what it did for the region. The history part is really important, and, in my opinion, the biggest thing that came out of Apollo is the fact that so many young people got interested in science, technology, engineering, and math. I firmly believe that created the means by which the U.S. economy drove the world.

IM: What's Houston's role in the future of space exploration?

DA: On the space exploration side, NASA has announced that we're going to go back to the moon by 2024. Now, that's a huge challenge. The NASA administrator, Jim Bridenstine, who's a Rice graduate, is aware of those challenges. Whether it's 2024 or if we have to wait until 2028, a lot of that work is going to be driven by what's being done in Houston, particularly the Johnson Space Center. There's a big rocket that they're developing, as well as the Orion capsule, Houston has a big role in those.

On the commercial side, there's the Houston Spaceport, which was the 10th licensed commercially licensed spaceport in the United States. There's now 12 within the United States, but Houston's spaceport is the only one located in a large city. There's a great company out there called Intuitive Machines, and they just got one of the lunar landing contracts. So, sometime between now and 2021, there may actually be a piece of hardware land on the moon that was built here in Houston.

IM: What should the Houston innovation ecosystem be focused on?

DA: The pieces are all there. We just need to work together to get them working coherently. If you get someone who understands space data talking to one of these companies who are trying to monitor flooding, for example, then both of those groups will grow together. We need to start bringing them together.

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Portions of this interview have been edited.

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Building Houston

 
 

San Diego-based rBIO moved to Houston to take advantage of the growing ecosystem of biomanufacturing and synthetic biology. Photo via Getty Images

Cameron Owen had an idea for a synthetic biology application, and he pitched it to a handful of postdoctoral programs. When he received the feedback that he didn't have enough research experience, he decided to launch a startup based in San Diego around his idea. He figured that he'd either get the experience he needed to re-apply, or he'd create a viable company.

After three years of research and development, Owen's path seems to have taken him down the latter of those two options, and he moved his viable company, rBIO, to Houston — a twist he didn't see coming.

“Houston was not on my radar until about a year and a half ago,” Owen says, explaining that he thought of Houston as a leading health care hub, but the coasts still had an edge when it came to what he was doing. “San Diego and the Boston area are the two big biotech and life science hubs.”

But when he visited the Bayou City in December of 2021, he says he saw first hand that something new was happening.

“Companies from California like us and the coastal areas were converging here in Houston and creating this new type of bioeconomy,” he tells InnovationMap.

Owen moved to Houston last year, but rBIO still has an academic partner in Washington University in St. Louis and a clinical research organization it's working with too, so he admits rBIO's local footprint is relatively small — but not for long.

"When we look to want to get into manufacturing, we definitely want to build something here in Houston," he says. "We’re just not to that point as a company."

In terms of the stage rBIO is in now, Owen says the company is coming out of R&D and into clinical studies. He says rBIO has plans to fundraise and is meeting with potential partners that will help his company scale and build out a facility.

With the help of its CRO partner, rBIO has two ongoing clinical projects — with a third coming next month. Owen says right now rBIO is targeting the pharmaceutical industry’s biologics sector — these are drugs our bodies make naturally, like insulin. About 12 percent of the population in the United States has diabetes, which translates to almost 40 million people. The demand for insulin is high, and rBIO has a way to create it — and at 30 percent less cost.

This is just the tip of the iceberg — the world of synthetic biology application is endless.

“Now that we can design and manipulate biology in ways we’ve never been able to before,” Owen says, "we’re really only limited by our own imagination.”

Synthetic biology is a field of science that involves programing biology to create and redesign natural elements. While it sounds like science fiction, Owen compares it to any other type of technology.

“Biology really is a type of software,” he says. “Phones and computers at their core run on 1s and 0s. In biology, it’s kind of the same thing, but instead of two letters, it’s four — A, C, T, and G.”

“The cool thing about biology is the software builds the hardware,” he continues. “You put that code in there and the biology builds in and of itself.”

Owen says the industry of synthetic biology has been rising in popularity for years, but the technology has only recently caught up.

“We’re exploring a brave new world — there’s no doubt about that,” Owen says.

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