Commercial space technology is being developed at this moment, and Arturo Machuca wants to make sure the Houston Spaceport is ready for the technology when it's finished. Courtesy of the Houston Airport System

In 2015, Houston became the 10th licensed spaceport in the United States. Now, four years later, it's Arturo Machuca's job as general manager of the Houston Spaceport and Ellington Airport to guide the institution from idea into reality.

Ellington Airport and the Houston Spaceport are co-located just 15 miles outside of downtown Houston and just north of the Johnson Space Center. While major players in commercial space exploration develop the technology for space travel, Machuca and his team at the Houston Airport Systems are working to build Houston's Spaceport to be ready for that technology when it arrives.

Machuca spoke with InnovationMap for the final installment of this month's space-focused interviews in honor of the 50th anniversary of the Apollo 11 landing.

InnovationMap: Tell me a little bit about your career to date. 

Arturo Machuca: I am a very fortunate man in that I have had the chance to be involved in this project that's so relevant to the city of Houston. My background has been in aviation for 38 years. I've worked 21 years in commercial aviation. I've also worked in air service development, working with airlines to add new routes to and from Houston. I've worked in corporate aviation as well.

Now past 10 years since July 2009 been with the Houston Airport System. I was first based at the George Bush Intercontinental Airport, then in 2012 I was fortunate enough to work with director Mario Diaz on the inception of the spaceport plans. In 2015, we became the 10th commercial spaceport in the nation.

It's been so much fun. It's so good to come to work where you get to say, "I'm having fun with this."

IM: With the Houston Spaceport being only the 10th licensed in the United States, has it been challenging laying the groundwork?

AM: There has been some challenges in that we are adapting our infrastructure to serve as the commercial space, including very in depth due diligence. But at the same time, it's been easy because of the fact that we are distinguished amongst other spaceports. We are the only truly urban spaceport in the world, which makes it easier from my perspective. Plus, we are the home to Johnson Space Center and a number of space companies based here. While challenging, it's been very good to have those things on our side.

IM: What’s the big picture goal of the Houston Spaceport?

AM: Our goal will be to one day connect Houston to the world by commercial spaceflight. Companies like Virgin Galactic are developing their technology for point-to-point transportation, or space flight. We have no control over that — it's up to them. In the meantime, we continue to take advantage of existing structure and turning it into the spaceport. We use what we already have at Ellington Airport. We're serving aviation today until commercial spaceflight gets here.

IM: The Spaceport just broke ground on Phase I of the transformation. What are the priorities for that initiative?

AM: We have nearly 1,000 acres of land that we can develop. Our vision is to create a cluster of aerospace and aviation companies that allow for us to get to space in a quicker fashion. We have chosen four major areas of development to focus on phase one of the spaceport: drones, micro satellites, aviation and commercial spaceflight, and data and analytics. We're building the neighborhood, if you will, so that companies can come and set up on our land.

We've been working with universities, and about a month ago we just announced the Edge workforce training center where San Jacinto College will train students to support the industry.

IM: The spaceport has quite a few educational partners. Why has that been such a core component to the project?

AM: About 2.5 years ago we were working with a proposal to work with Blue Origin — a company owned by Jeff Bezos, the owner of Amazon. Blue Origin was looking for a location to build their rocket engine, and we thought the Houston Spaceport was the perfect place. The process took a little over a year, and I am proud to say that we made it to the final two cities. We were competing with Huntsville, Alabama, which is known as Rocket City. We didn't win, but when we went back and asked for feedback, they said that Huntsville offered a tremendous amount of educational support. We clearly realized that it's important to have that direct connection.

IM: What’s Houston’s future role in space?

AM: I think that Houston is poised for success because of the existing components we already have in place, like the Johnson Space Center. The city of Houston is working very closely with the JSC to make sure we remain mission relevant.

Pushing into commercial space flight, I believe that Houston is poised for a tremendous future. We are learning to better coordinate with the players on the government side and the private industry. I envision Houston becoming even a stronger player in the next 50 years because of the development and the growth of assets. I can see us serving as a city where we take passengers from one end of the world to the others using commercial space flight.

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Portions of this interview have been edited.

Mario Diaz, CEO of the Houston Airport System addresses the crowd gathered to celebrate the Apollo 11 anniversary this weekend. Natalie Harms/InnovationMap

Overheard: Aerospace and airport VIPs commemorate Space City Month at IAH

Out of this world

Houston, we have liftoff of a space-filled weekend. Saturday, July 20, marks the 50th anniversary of Apollo 11 touching down on the moon, and that calls for a celebration, as well as a commemoration.

Houston First, Space Center Houston, NASA, and United Airlines teamed up to host an international delegation at George Bush Intercontinental Airport in Terminal C on July 17. Various space or Space City VIPs took the stage to discuss their memories of the lunar landing and the role Houston played in the monumental event.

“Our hope is to be an airport system that reflects Houston’s role as a leader on the global stage and to have our city standing as truly international business and cultural center. With both Bush and Hobby airports having earned four-star ratings, we are built to meet those expectations.”

— Mario Diaz, executive director at Houston Airport System. Bush Intercontinental Airport is also celebrating its 50th anniversary since opening in 1969.

“It is the innovative spirit of the people of this city that help give the world our new perspective. We are all neighbors, and we must all face the future as one. How wonderful that understanding is now with Houston having become the nation’s most diverse city in the country with one in four Houstonians being foreign born.”

— Houston Mayor Sylvester Turner, referencing a ranking released earlier this year.

“This week, we are celebrating this anniversary and time when we did so much more than we thought we could. … [the Apollo mission] was an inspiration to us then, and I think continues to be an inspiration to all of us even now.”

Peggy Whitson, former NASA astronaut who holds the record for the United States for her 665 days in space.

“Houston is the Space City, because the Johnson Space Center is the home of human space flight. As you know, ‘Houston’ was the very first word spoken from the surface of the moon. And, it wasn’t a fluke. They knew who they needed to talk to, and it was Houston.”

— Mark Geyer, director of NASA's Johnson Space Center.

“In roughly three years, we will have astronauts back in the region of the moon — this time women and men. And soon after that, back onto the surface of the moon again in our mission called Artemis.”

— Geyer continues to say of NASA's lunar exploration plans.

“Just a few weeks ago, [Space Center Houston] inaugurated the completely restored mission control operations room from the Apollo era. We’ve done a restoration and taken it back to the 1960s, and it appears as if the flight controllers just got up to take a break.”

— William Harris, CEO of Space Center Houston. The organization is NASA's official tourism arm and houses 250,000 square feet of indoor and outdoor exhibition space.

Steven Gonzalez wants to give NASA technology to startups for free. Courtesy of NASA

Houston-based NASA technology strategist aims to connect the entity to startups and technologies across the country

Featured innovator

NASA has 1,400 technologies that are available for licensing across industries, but only 20 percent of those technologies have been licensed — traditionally by mid- to large-sized companies.

NASA Technology Transfer Strategist Steven Gonzalez, who's had a 30-year career at NASA at the Johnson Space Center, is responsible for moving these technologies out into the community. About four years ago, his department created a program to target startups and engage them with the organization's technology. Startup NASA is a program in which startups can license NASA technology for free for three years before the licensing fees kick in.

"We thought that once we created this program we'd have startups coming to break the door down to get these technologies, and that isn't the case," Gonzalez tells InnovationMap. "So, what I've been focusing on is trying to find was to connect to ecosystems across the country to introduce them to this program and our technology and find people who will be the bridge between us and these ecosystems."

All this month, with the world's focus on the 50th anniversary of Apollo 11, Gozalez is able to benefit from this momentum and reenergized focus on space. He spoke with InnovationMap about his career in space and the future Houston will play in the next 50 years.

InnovationMap: What initially got you interested in space and how did it turn into a career?

Steven Gonzalez: Star Trek, the original series. I had the desire to be Captain Kirk and be on the Starship Enterprise. I was born in New York, and raised in the Northeast. In 8th grade, I already had the bug to go to NASA and be the first in my family to go to college. I remember having all my classes picked out with college course credit, and — by this time we had moved to New Jersey, and we were only the second Spanish family there — the guidance counselor looked at my schedule and told me I would be better going to autoshop.

I went to Boston University and then got my master's at Texas A&M University. Right after A&M, I started at the Johnson Space Center in 1988, and I was working in mission control bringing in new technology. I remember getting there and expecting to see something along the lines of the Starship Enterprise, and it looked the same as it did from the Apollo timeframe. After that, I trained astronauts for a couple years before going back and working to bring the new control center online. The Houston Chronicle compared it to the tech on the Starship Enterprise, and I finally felt like I had arrived.

IM: From your strategic roles to now managing technology, what are some of the challenges you've faced in your NASA career?

SG: I looked at the 20-year strategy for the Johnson Space Center and how to get it positioned for the growth of commercial and international space. It was a great role, and the challenge for NASA predicting a long-term strategy was that every four or eight years, we get a new president, and when we get a new president, we get a new direction. We did all this strategy planning and using all the tools — this was in 2006 before we knew what Elon Musk or Jeff Bezos were up to — and we said that over 20 years, we predicted that the commercial market would grow and our role would have to shift. That was a hard message to swallow at that time when we had so much going on.

After working in strategy, I shifted to focus on partnerships, and now my role is technology transfer. After most of my career focused on impacting life space, now this last part of my career is focused on impacting life here on earth. My role now is to move technology out and find technology to bring in — mostly moving technology into startups around the country.

Now, my challenge in my role of moving technology out is that, especially when we go to startups, people think of NASA technology as being space technology. But, of our 1,400 technologies we have, so many of them have already impacted all different industries. So, trying to get people to figure out how to connect to the startup ecosystems is another challenge.

IM: What's been the effect on NASA now that commercialization has ramped up?

SG: First, we were created with a two-fold mission — to explore and to benefit humanity. From day one we have been moving our technology out. Unfortunately, we at NASA have the reputation of giving to the world Tang and Velcro, and neither one of that is true. The reality is so much more fantastic. The camera on our phones and LASIK came from NASA technology. There's a technology I love to talk about. We were working with Texas Children's Hospital, and they had a challenge of moving premature infants from room to room. The gurney would vibrate quite a bit and hurt their internal organs — some would even pass away from this. Our astronauts train two to three hours a day to keep their muscles and bones up and running, so they exercise on treadmills and bikes on the space station. Left unchecked, those vibrations from the equipment would ruin the experiments on the space station. So, we have the technology and expertise here in Houston that we worked with TCH and created a carrier that allows these children to be transferred without any harm to them.

The second part is that our technology is seeding this new commercial space market. Back in the '90s here in Houston, we developed a technology that was an inflatable habitat. When we send astronauts to the moon or mars, they need a spacious habitat that isn't too heavy to be transported via spacecraft. So, we created that technology, and Bob Bigelow, who owns a bunch of hotels and wanted to have the first hotel in space, long story short, he licensed our technology, created this hotel that's circling space and waiting until Uber can transport his paying customers up there. In the process, he thought that NASA and the ISS can use it in the meantime. So it's a technology we started, but we didn't have to commercialize it, someone else did the full development of it.

IM: So, it sounds like it's much more collaborative of a relationship between NASA and commercial entities than it is competitive, would you say?

SG: I'm glad you brought that up. A lot of times people think it's a competition. In the 1960s, it was a competition between us and the Russians. Then, the space station became this collaborative community. With the commercial market now, people keep talking about it being a competition, but in reality we need one another. We have 60 years of history that they can stand on and they are doing things differently that we're learning from. Also, we still are doing things that are tougher to make money on. We do things that has no return on investment, and the commercial companies are focusing on things they can make a market for.

IM: What role do you see Houston playing in the future of space?

SG: Right now, it's a bit premature to really talk about anything, but we're in conversations with various startup organizations about growth and collaborations. Between NASA, the Houston Spaceport, and the annual SpaceCom, Houston in an incredible position to be the hub for this growing, trillion-dollar commercial space market. Through events like SpaceCom, we are a hub for a lot of international activity. Houston already being a hub for international travel and business already, it could be an international gateway for the space industry.

IM: What does Space City Month mean to you and the city of Houston?

SG: We've always been the Space City, but for a while there, it was taken for granted. It's part of our history, but it's nice to see it brought back into the foreground to realize that it's not just history, it's who we are today. It's been better over the past few years as we've seen this conversation increasing. This anniversary is bringing back to the forefront how Houston embraces space for the future.

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Portions of this interview have been edited.

David Alexander of the Rice University Space Institute says Houston's past accomplishments in space aren't all the Space City has to offer. Photo courtesy of Rice University

Rice University's Space Institute director on the future of exploration, development, and the role Houston will play in space

Featured Innovator

While the city is celebrating the 50th anniversary of the Apollo mission that got man to the moon, this month should also be about looking forward to the Space City's future.

From commercial space travel momentum to upcoming governmental projects, there's a lot in the works for space, and Houston will play a big role in both sides of the equation, says David Alexander, director of the Rice University Space Institute.

"In Houston, we tend to think of space as a destination, but it really is a resource," he says. "And we need to be thinking about it as a resource."

New, and increasingly more accessible technologies are changing the landscape — especially for universities. Smaller satellite devices, called CubeSacs, are so easy to build and launch into space that students are able to it themselves, Alexander says, and they are. These projects across the country are collecting new data on a massive level.

"Students these days really want to solve meaningful problems rather than just academic problems, and space is way of giving them access to what information and data that can help them with that," Alexander says.

Alexander shared his thoughts and professional opinion on some of the exciting advancements the space industry has on its radar — and where Houston comes into play for these initiatives.

InnovationMap: What got you really interested in space exploration?

David Alexander: I was always interested in science, but one of the things got really interested in the human aspect of space was an event at the Rice Baker Institute a few years ago, shortly after the cancellation of the shuttle program. It was just a great discussion about the space in general, but what kind of hit me hard was the fact that a lot of history — we're talking about 50 years in space since the Apollo mission — has influenced the whole world. Modern human history has been hugely impacted by the presence of space, and a lot of that happened in Houston. And, some of the people who've made it happen are still around, and that day at the Baker Institute, some of them were there. So, that hit home for me.

IM: What are some of the focuses of the Rice Space Institute?

DA: We've got the outreach part, then we have the the science, the research, and then student activities and the connection to NASA that we have.

We have a professional master's program for students who are not particularly interested in research, but what they want to do is combine management and business training with technical training in science and engineering related to space. We've been building that program all for over the last six years or so. We also have this fairly popular public lectures series that we've been running since January of 2011.

One of the prime reasons for institutes at Rice, which are small entities, is to bring faculty from different disciplines together. And so that's been our primary effort when it comes to research. We'll try and get some of the bioengineers, for instance, working with NASA on the human side, and get some of the engineers working with NASA on things like sensor wireless technologies.

IM: What does the future of space exploration look like to you?

DA: I think one of the things that we're seen this helping drive that difference between now and then is the growth in the private and commercial enterprises in space. I think that what we're finding is that space is becoming more accessible. The actual cost of getting to space is radically coming down, and the kind of resources that we can put in space and the capability of these resources is changing.

IM: Do you think there's been a resurgence of interest in space lately?

DA: NASA made space kind of look routine, which is good because you want astronauts to be safe and you want your hardware to survive. So, it became less exciting. However, within the government side of things, that has been a huge steady progress. You can follow the path from the technology development all the way through to today. But I think from the general public's perception, people like Elon Musk, even though he has some ambitious ideas, has seen successes with reusable rockets with these landings. And people like Jeff Bezos, who are also developing their own rockets and their own plans for space, have kind of opened people's eyes again a little bit. I think they have added a bit of star power, and they have shown an excitement for space that's infectious.

IM: What does the celebration of the 50th anniversary of the Apollo 11 mission mean to the city of Houston?

DA: There's a balance that we have to find between looking too much in the past — you don't want to see your successes in the rearview. I think we should rightly be proud of the Apollo history and what it did for the region. The history part is really important, and, in my opinion, the biggest thing that came out of Apollo is the fact that so many young people got interested in science, technology, engineering, and math. I firmly believe that created the means by which the U.S. economy drove the world.

IM: What's Houston's role in the future of space exploration?

DA: On the space exploration side, NASA has announced that we're going to go back to the moon by 2024. Now, that's a huge challenge. The NASA administrator, Jim Bridenstine, who's a Rice graduate, is aware of those challenges. Whether it's 2024 or if we have to wait until 2028, a lot of that work is going to be driven by what's being done in Houston, particularly the Johnson Space Center. There's a big rocket that they're developing, as well as the Orion capsule, Houston has a big role in those.

On the commercial side, there's the Houston Spaceport, which was the 10th licensed commercially licensed spaceport in the United States. There's now 12 within the United States, but Houston's spaceport is the only one located in a large city. There's a great company out there called Intuitive Machines, and they just got one of the lunar landing contracts. So, sometime between now and 2021, there may actually be a piece of hardware land on the moon that was built here in Houston.

IM: What should the Houston innovation ecosystem be focused on?

DA: The pieces are all there. We just need to work together to get them working coherently. If you get someone who understands space data talking to one of these companies who are trying to monitor flooding, for example, then both of those groups will grow together. We need to start bringing them together.

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Portions of this interview have been edited.

A delegation from Houston consisting of former astronauts, aircraft experts, and local leaders were invited to the Paris Air Show to represent the Space City. Photo courtesy of the Greater Houston Partnership

Houston takes flight at Paris Air Show just in time for Space City Month​

Oui, oui

As we move closer to the 50th anniversary of Apollo 11 in mid-July, eyes around the world are turning to the United States and to Houston's NASA Johnson Space Center in celebration of the historic mission that first brought mankind to the moon. Thanks to that unprecedented interest, Houston was asked to be a featured partner of the USA Partnership Pavilion at the Paris Air Show last month.

Drawing nearly 2,500 exhibitors from 49 countries and more than 316,000 total visitors, the Paris Air Show continues to be the world's premier aerospace and aviation industry event. Houston's historic achievements set the stage to showcase how the region continues to be a global hub for technology and innovation.

A delegation of top Houston organizations brought distinct assets that showcased a collective advantage in competing for aerospace business. Led by the Greater Houston Partnership under the promotional banner Space City: The Gateway to Innovation, the group included:

  • Houston Spaceport, one of the nation's 10 licensed commercial spaceports co-located at Ellington Field (EFD).
  • Rice Space Institute, which has helped to establish Rice University's international reputation in all areas of space research by investing in efforts to further the development of new ideas and innovation in the broad area that is space exploration and utilization.
  • SpaceCom, the Space Commerce Conference and Exposition, an annual two-day conference that connects NASA technology with the private sector to fuel future innovation
  • Space Center Houston, the official visitor center of NASA's Johnson Space Center and a leading science and space learning center.
  • Blue Bear Capital, a Houston-based venture capital firm investing in fast-growing private companies that apply data driven technologies and innovative business models to the global energy supply chain.
  • Trumbull Unmanned, A Forbes Top 25 Veteran Founded startup based out of the Houston Spaceport that collects, analyzes, and visualizes critical data for the energy sector, primarily supporting oil and gas and environmental efforts.

As an anchor NASA community and home to the sharpest minds in aerospace, life sciences, energy and innovation, it was only fitting that Houston have a prominent presence in the show at Le Bourget. Among the 300 exhibitors representing the United States in the USA Partnership Pavilion, twenty of which were states, Houston was the only city with a major presence. Throughout the week, the Houston delegation participated in a schedule of high-profile thought-leadership and hospitality events to engage and educate global industry and government decision-makers and influencers.

For our part at the Greater Houston Partnership, we were able to conduct a series of meetings with companies from around the world, gathering more than 40 international and domestic economic development leads. The show is also a great media opportunity that allowed us to secure nearly 20 interviews for our delegation members with print and broadcast outlets from across the U.S. and Europe.

The USA Partnership Pavilion's week-long celebration of innovation and human achievement was led Apollo Astronauts Brig. Gen. Charlie Duke, and Houston-natives Col. Walt Cunningham and Col. Al Warden. Their presence served as a tangible way to connect our nation's achievements to the innovative future of the global aerospace industry.

"The 50th anniversary is such a unique time in history. It gives us an opportunity to think back about what we did, realize where we are today, and where we want to be in the future," says Col. Al Worden, "The most important thing about the space program was not so much about putting a man on the moon, it was about developing the technology to get there. Those technologies have made this country so successful, and I hope we continue to see that type of commitment to technology development in the future."

Houston delegates were asked to participate in several thought leadership panels.

"As we continue to explore further into the universe, there are a myriad of technical challenges that need to be overcome," says David Alexander, director of Rice Space Institute, who moderated a panel discussion on advancing technologies that will help humans physically and mentally adapt to deep space exploration. He was joined by industry leaders from United Launch Alliance (ULA), Lockheed Martin, Virgin Galactic, and Harris Corporation for the conversation centered around the use of artificial intelligence, 3D printing and additive manufacturing.

Governments around the globe including those in Europe, China and of course the United States have accelerated a discussion about sending humans back to the moon as a key step in our continued human exploration of deep space. This concept is also proving attractive to private companies, with an increase in public-private partnerships and a broader role being played by commercial entities in government aspirations.

Former astronaut and Space Station Commander turned venture capital leader Tim Kopra participated in a panel discussion on this very topic alongside representative from United Launch Alliance (ULA), the Federal Aviation Administration (FAA), Lockheed Martin, Deloitte, and the U.S. Air Force. Although Kopra's Blue Bear Capital's primary target are data-driven technologies in the energy industry, he notes that "there are a lot of intersections between energy and aerospace, and Houston's melting pot of global industries has turned the region into a hot bed for innovation with broader application of technologies."

The centerpiece of the Houston delegation's presence at the Paris Air Show was an executive briefing on June 19 featuring keynote remarks from Kopra that helped set the tone for the work Houston continues to do in innovation and aerospace technology. Kopra discussed his background with NASA, the transition into the funding scene that supports the region's growing innovation ecosystem, and what Houston has to offer businesses looking to expand their operations in the areas of aerospace, manufacturing, and digital technology.

A panel discussion followed, addressing topics that included educating the next generation of engineers and explorers, the intersection of NASA technology and the private sector, the next frontier of space exploration and the unique position that Houston has in pioneering those efforts.

"Over the past 58 years, Johnson Space Center has led the U.S. and the world in human exploration, discovery, and achievement in space," Kopra tells the audience. "Now we are in a position of transitioning a lot of those capabilities into the civilian sector."

The Houston Spaceport is one big step in that ongoing evolution. As the only commercial spaceport in the nation centered in a large metropolitan area, the Houston facility will have unmatched access to resources for companies and operators, said Arturo Machuca, general manager of the spaceport.

"The Houston Spaceport is being developed to ensure Houston stays relevant in commercial aerospace and aviation activities," he says. "Houston continues to hold a strong value proposition for companies looking to enter the aerospace industry with a unique set of advantages including the proximity to NASA's Johnson Space Center, unparalleled infrastructure through the Houston Airport System, and a strong talent base."

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Josh Davis is the director of International Investment and Trade at the Greater Houston Partnership and organized the Partnership's participation at the Paris Air Show and gathered the delegation.

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Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”

10+ Houston innovation leaders in the spotlight at SXSW 2026

where to be

Houston's innovation scene will be well represented at South by Southwest (SXSW) this month.

The week-long, Austin-based conference and festival will spotlight some of the Bayou City's leaders in health care, energy, space and more. The event kicks off today, March 12, and runs through March 18. The SXSW Innovation Conference will feature keynotes, workshops, mentoring sessions and more throughout various venues in the city.

Here's who to see and when and where to find them:

March 12

Aileen Allen, venture partner at Mercury Fund

Mentor Session from 4-5:15 p.m. at Hilton Austin Downtown

Allen will host a mentoring session focused on funding, marketing, advertising, PR and the future of work.

March 13

Heath Butler, partner at Mercury Fund

SXSW Pitch-Smart Cities, Transportation, Manufacturing & Logistics from 2:30-3:30 p.m. at the J.W. Marriott

Butler will judge five innovative startups as they pitch their solutions to advance smart cities, enhance transportation systems, modernize manufacturing, transform logistics, and strengthen government infrastructure and civic operations.

Jonathan Cirtain, CEO and president of Axiom Space

The Clock is Ticking for Space - Replacing the ISS from 4-5 p.m. at the J.W. Marriott

Cirtain will discuss Axiom's pursuit of building the world’s first commercial space station.

March 14

Jesse Martinez, founder and CEO of LSA Global

SXSW Pitch-Intelligent Systems, Robotics, & Multisensory Technology from 10-11 a.m. at the J.W. Marriott

Martinez will judge five innovative startups as they pitch their technologies that aim to enhance the way people connect, communicate and share unique life experiences with those around them in a digital ecosystem.

Jennifer Schmitt, head of operations at Rhythm Energy

Powering Texas with Reliable Integrated High-Demand Energy from 10-11 a.m. at Marlow

Schmitt will join a panel to discuss how EirGrid, the state-owned electric power transmission operator in Ireland, is pioneering solutions as the country works toward 80 percent renewable integration by 2030.

Saki Sasagawa, director of business development for JETRO Houston

Now is Japan's Time: Leading the Future with Deep Tech from 10-11 a.m. at the J.W. Marriott

Sasagawa joins a panel that will share real-time insights from diverse perspectives on the forefront of Japan’s deep tech and IP businesses.

March 15

Bosco Lai, CEO and co-founder of Little Place Labs

SXSW Pitch Alumni: Where Are They Now? from 10-11 a.m. at the J.W. Marriott

Lai joins a panel of four former SXSW Pitch winners to share how they leveraged the platform to take their startups to the next level.

Tara Karimi, cofounder and chief science and sustainability officer at Cemvita

South by South America: The Rise of Southern Brazil Tech from 2:30-3:30. p.m. at The Line

Karimi will participate in a panel to discuss how Rio Grande do Sul, Brazil's southernmost state, is attracting elite talent and AI infrastructure and share insights on navigating the next wave of South American tech growth.

March 16

Dr. Pavitra P. Krishnamani, emergency medicine physician at The University of Texas MD Anderson Cancer Center

Viva La Revolution: How the Digital Age is Transforming Wellness from 11:30 a.m.-12:30 p.m. at Hilton Austin Downtown

Krishnamani will discuss the latest advancements and policies that can accelerate the digital age of health care, such as wearables, telehealth and artificial intelligence.

March 18

Charlie Childs, co-founder and CEO of Intero Biosystems

Spinning Out: What It Takes to Build a University Startup from 2:30-3:30 p.m. at The Line

Childs will join founders who spun their companies out of the University of Michigan to share the real story of navigating IP, early capital, team building, market validation and the “valley of death.”

Dr. James Allison, regental chair of immunology and director of The Allison Institute at The University of Texas MD Anderson Cancer Center

Dr. Padmanee Sharma, professor in the Department of Genitourinary Medical Oncology, Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center

Beyond Checkpoints: Immunotherapy’s Next Act from 2:30-3:30 p.m. at the J.W. Marriott

Allison and Sharma will sit down with 21-year-old, Stage 4 cancer survivor Sharon Belvin and Time Magazine journalist Alice Park will discuss the future of immunotherapy and what challenges remain.

Last year, Houston startups Little Places Labs and Helix Earth won top prizes in their respective categories at the prestigious SXSW Pitch event, held this year from March 13-14. No Houston startups were named finalists to compete in this year's event.

NASA revamps Artemis moon landing program by modeling it after Apollo

To the moon

NASA is revamping its Artemis moon exploration program to make it more like the fast-paced Apollo program half a century ago, adding an extra practice flight before attempting a high-risk lunar landing with a crew in two years.

The overhaul in the flight lineup came just days after NASA’s new moon rocket returned to its hangar for more repairs, and a safety panel warned the space agency to scale back its overly ambitious goals for humanity’s first lunar landing since 1972.

Artemis II, a lunar fly-around by four astronauts, is off until at least April because of rocket problems.

The follow-up mission, Artemis III, had been targeting a landing near the moon’s south pole by another pair of astronauts in about three years. But with long gaps between flights and concern growing over the readiness of a lunar lander and moonwalking suits, NASA’s new administrator Jared Isaacman announced that mission would instead focus on launching a lunar lander into orbit around Earth in 2027 for docking practice by astronauts flying in an Orion capsule.

The new plan calls for a moon landing — potentially even two moon landings — by astronauts in 2028.

“Everybody agrees. This is the only way forward,” Isaacman said.

The hydrogen fuel leaks and helium flow problems that struck the Space Launch System rocket on the pad at NASA's Kennedy Space Center in February also plagued the first Artemis test flight without a crew in 2022.

Another three-year gap was looming between Artemis II and the moon landing by astronauts as originally envisioned, Isaacman said.

Isaacman stressed that “it should be incredibly obvious” that three years between flights is unacceptable. He'd like to get it down to one year or even less.

Isaacman, a tech billionaire who bought his own trips to orbit and performed the world’s first private spacewalk, took the helm at NASA in December.

During NASA’s storied Apollo program, he said, astronauts’ first flight to the moon was followed by two more missions before Neil Armstrong and Buzz Aldrin landed on the moon. What's more, he added, the Apollo moonshots followed one another in quick succession, just as the earlier Projects Mercury and Gemini had rapid flight rates, sometimes coming just a few months apart.

Twenty-four Apollo astronauts flew to the moon from 1968 through 1972, with 12 of them landing.

“No one at NASA forgot their history books. They knew how to do this," Isaacman said. “Now we're putting it in action.”

To pick up the pace and reduce risk, NASA will standardize its Space Launch System rockets moving forward, Isaacman said. These are the massive rockets that will launch astronauts to the moon aboard Orion capsules. At the same time, Elon Musk's SpaceX and Jeff Bezos' Blue Origin are speeding up their work on the landers needed to get the astronauts from lunar orbit down to the surface.

Isaacman said next year will see an Orion crew rendezvousing in orbit around Earth with SpaceX's Starship, Blue Origin's Blue Moon or both landers. It's similar to the methodical approach that worked so well during Apollo in the late 1960s, he noted. Apollo 8, astronauts' first flight to the moon, was followed by two more missions before Armstrong and Aldrin aimed for the lunar surface.

“We should be getting back to basics and doing what we know works,” he said.

The Aerospace Safety Advisory Panel recommended that NASA revise its objectives for Artemis III “given the demanding mission goals.” It’s urgent the space agency do that, the panel said, if the United States hopes to safely return astronauts to the moon. Isaacman said the revised Artemis flight plan addresses the panel's concerns and is supported by industry and the Trump administration.