Uniquely Houston event to convene innovation experts across aerospace, energy, and medicine

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For the eighteenth year in a row, the annual Pumps & Pipes event will showcase and explore convergence innovation and common technology themes across Houston’s three major industries. Image courtesy of Pumps & Pipes

Every year, Houston's legacy industries — energy, medicine, and aerospace — come together to share innovative ideas and collaborate on future opportunities.

For the eighteenth year in a row, the annual Pumps & Pipes event will showcase and explore convergence innovation and common technology themes across Houston’s three major industries. The hosting organization, also called Pumps & Pipes, was established in 2007 in Houston and is dedicated to fostering collaboration amongst the city's three major industries.

With NASA in its backyard, the world’s largest medical center, and a reputation as the “Energy Capital of the World,” Houston is uniquely positioned to lead in cross-industry convergence innovation and is reflected in the theme of this year’s event – Blueprint Houston: Converge and Innovate.

Here's what you can expect to explore at the event, which will take place this year on December 9 at TMC Helix Park. Tickets are available online.

The state of Texas’ aerospace investments

How are the recent strategic investments in aerospace by the State of Texas transforming the space economy and driving growth in adjacent industries? What is the case for cultivating a more dynamic and vibrant aerospace R&D environment?

These are the key questions explored in the opening session of Pumps & Pipes, moderated by David Alexander (Director, Rice Space Institute). Joining the discussion are distinguished leaders Norman Garza, Jr., Executive Director of the Texas Space Commission (TSC); as well as two members of the TSC board of directors: Sarah “Sassie” Duggelby, CEO/Co-Founder of Venus Aerospace; and Kathryn Lueders, GM at Starbase, SpaceX.

This panel will spotlight Texas’ critical role in shaping the future of aerospace, with a focus on its cross-sector impact, from space exploration to innovation in energy and health care. We’ll explore how the state’s investments are fueling research and development, creating economic opportunities, and fostering a more interconnected, high-tech ecosystem for the future.

Real-world applications of robotics and synthetic biology

Explore the groundbreaking intersection of syntheticbiology and robotics as they reshape industries from aerospace to energy to health care. Experts from academia and industry — Rob Ambrose of Texas A&M University, Shankar Nadarajah of ExxonMobil, Shalini Yadav of the Rice Synthetic Biology Institute, and Moji Karimi of Cemvita — will discuss the real-world applications and future possibilities of these two fields, including innovative uses of robotics and drones to monitor emissions from deep-sea oil rigs, and synthetic microbes that convert carbon dioxide into valuable chemical products.

Discover how synthetic biology and robotics are paving the way for a more sustainable, autonomous, efficient, and interconnected future.

The total artificial heart – a uniquely Houston story

Heart failure affects millions globally, yet only a small fraction of patients receive life-saving heart transplants. The Total Artificial Heart (TAH), developed by BiVACOR, offers a revolutionary solution for patients with severe heart failure who are ineligible for a transplant.

Luminary leader, Dr. Billy Cohn, will discuss the groundbreaking BiVACOR TAH, a device that fully replaces the function of the heart using a magnetically levitated rotary pump. This innovative approach is part of an FDA-approved first-in-human study, aiming to evaluate its use as a bridge-to-transplant for patients awaiting heart transplants.

Moderated by Dr. Alan Lumsden (Chair Dept. of CV Surgery at Houston Methodist Hospital), join Dr. Cohn as he shares insights, and the story-behind, this pioneering technology and its potential to reshape the future of heart failure treatment, offering new hope to thousands of patients in need.

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Stuart Corr is the director of innovation engineering at The Bookout Center at Houston Methodist and executive director of Pumps & Pipes.

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The projects focus on an array of topics from the challenges of harmful space radiation to the reliability of space robots. Photo via Pexels

Rice University awards $150,000 to space researchers

future of space

The Rice Space Institute has awarded $150,000 in seed funding to six university researchers to further their work in space-related science and engineering.

The projects each will receive $25,000 until June 2025, according to Rice. They focus on an array of topics from the challenges of harmful space radiation to the reliability of space robots.

“These projects collectively represent RSI’s commitment to pioneering studies that advance Rice’s space research portfolio,” RSI Director David Alexander, said in a statement.

The projects include:

  • Co-advancement of formal methods and prognostic digital twins for reliability and resilience of space robotics: The project aims to make space robots more reliable by improving the lifespan of robotic components operating in space.
  • Development of 3D-printed waveguide arrays for snapshot spectrometers for Earth remote sensing observations: The project will develop 3D waveguide components and a hyperspectral imaging system that will help provide data on Earth's water cycle. It's led by Tomasz Tkaczyk.
  • Haptic sensory feedback augmentation to mitigate vestibular deficits following microgravity exposure: The project focuses on a device that uses vibrotactile feedback to improve astronauts' balance and movement impairments due to microgravity. It's led by Marcia O’Malley, Vanessa Sanchez, Shane King and Kyra Stovicek.
  • Modeling framework for bioelectricity and its effect on the mechano-biology of wounds to accelerate healing in microgravity environments: The project focuses on the effect of bioelectricity on wound healing in microgravity. It's led by Raudel Avila, Swathi Balaji and K. Jane Grande-Allen.
  • The role of the environment in planet formation: The project will develop a conference at at the Rice Global Paris Center for foster collaboration between Rice, RSI and international institutions for students, researchers and faculty. It's led by Megan Reiter.
  • Spark plasma sintered high-density and lightweight boron nitrides ceramics for radiation shielding applications: The project aims to create boron-nitride ceramics to shield against harmful space radiation. It's led by Robert Vajtai and Abhijit Biswas.

Earlier this year, Alexander was named to the first-ever Texas Aerospace Research and Space Economy Consortium Executive Committee, part of the new Texas Space Commission. TARSEC is composed of representatives of each higher education institution in the state and aims to ensure that Texas remains a "powerhouse" in the space industry, Lieutenant Governor Dan Patrick said in a release.

Meanwhile, The Translational Research Institute for Space Health, or TRISH, which is part of BCM’s Center for Space Medicine, announced plans to launch six more experiments into space this year, focused on topics ranging from motion sickness to genome alterations during space travel.
Here's who's at the helm of the newly announced Texas Space Commission. Photo courtesy of the Office of the Governor

Texas Space Commission launches, Houston execs named to leadership

future of space

Governor Greg Abbott announced the Texas Space Commission, naming its inaugural board of directors and Texas Aerospace Research and Space Economy Consortium Executive Committee.

The announcement came at NASA's Johnson Space Center, and the governor was joined by Speaker Dade Phelan, Representative Greg Bonnen, Representative Dennis Paul, NASA's Johnson Space Center Director Vanessa Wyche, and various aerospace industry leaders.

According to a news release, the Texas Space Commission will aim to strengthen commercial, civil, and military aerospace activity by promoting innovation in space exploration and commercial aerospace opportunities, which will include the integration of space, aeronautics, and aviation industries as part of the Texas economy.

The Commission will be governed by a nine-member board of directors. The board will also administer the legislatively created Space Exploration and Aeronautics Research Fund to provide grants to eligible entities.

“Texas is home to trailblazers and innovators, and we have a rich history of traversing the final frontier: space,” Lieutenant Governor Dan Patrick says in a news release. “Texas is and will continue to be the epicenter for the space industry across the globe, and I have total confidence that my appointees to the Texas Space Commission Board of Directors and the Texas Aerospace Research and Space Economy Consortium Executive Committee will ensure the Texas space industry remains an international powerhouse for cutting-edge space innovation.”

TARSEC will independently identify research opportunities that will assist the state’s position in aeronautics research and development, astronautics, space commercialization, and space flight infrastructure. It also plans to fuel the integration of space, aeronautics, astronautics, and aviation industries into the Texas economy. TARSEC will be governed by an executive committee and will be composed of representatives of each higher education institution in the state.

“Since its very inception, NASA’s Johnson Space Center has been home to manned spaceflight, propelling Texas as the national leader in the U.S. space program,” Abbott says during the announcement. “It was at Rice University where President John F. Kennedy announced that the U.S. would put a man on the moon—not because it was easy, but because it was hard.

"Now, with the Texas Space Commission, our great state will have a group that is responsible for dreaming and achieving the next generation of human exploration in space," he continues. "Texas is the launchpad for Mars, innovating the technology that will colonize humanity’s first new planet. As we look into the future of space, one thing is clear: those who reach for the stars do so from the great state of Texas. I look forward to working with the Texas Space Commission, and I thank the Texas Legislature for partnering with industry and higher education institutions to secure the future of Texas' robust space industry."

The Houston-area board of directors appointees included:

  • Gwen Griffin, chief executive officer of the Griffin Communications Group
  • John Shannon, vice president of Exploration Systems at the Boeing Company
  • Sarah "Sassie" Duggleby, co-founder and CEO of Venus Aerospace
  • Kirk Shireman, vice president of Lunar Exploration Campaigns at Lockheed Martin
  • Dr. Nancy Currie-Gregg, director of the Texas A&M Space Institute

Additionally, a few Houstonians were named to the TARSEC committee, including:

  • Stephanie Murphy, CEO and executive chairman of Aegis Aerospace
  • Matt Ondler, president and former chief technology officer at Axiom Space
  • Jack “2fish” Fischer, vice president of production and operations at Intuitive Machines
  • Brian Freedman, president of the Bay Area Houston Economic Partnership and vice chairman of Wellby Financial
  • David Alexander, professor of physics and astronomy and director of the Rice Space Institute at Rice University

To see the full list of appointed board and committee members, along with their extended bios, click here.

Vanessa Wyche, director of NASA’s Johnson Space Center and Rice University president Reginald DesRoches expanded upon their partnership. Photo by Jeff Fitlow/Rice University

Rice University boosts NASA's research and new lunar mission with renewed partnership

owls in space

Nearly 60 years ago, President John F. Kennedy made a bold declaration to the crowd of 40,000 gathered at Rice University’s football stadium — and to the world. America, said the young president, would land a man on the moon before the decade’s end.

“Why does Rice play Texas? We choose to go to the moon,” Kennedy said in the now-iconic speech on September 12, 1962. “We choose to go to the moon in this decade and do the other things, not because they are easy, but because they are hard.”

Indeed, heading back to the moon is hard, but the Ivy League of the South has just formalized a deal to assist NASA in doing so in the agency’s new lunar Artemis program. Rice University and NASA have extended their historic collaboration and partnership in which the two entities share research and develop educational outreach programs and opportunities.

Specifically, the new umbrella Space Act Agreement (SAA) covers participation by Rice and NASA personnel in joint research opportunities, STEM engagement, and educational activities, according to a Rice press announcement. This deal follows a decade of collaboration (starting with the 2012 SAA) and a previous extension in 2017.

And in a nod to the late president, the agreement also makes official NASA’s co-host participation in the upcoming Rice campus celebration that celebrates Kennedy’s legendary “We choose to go to the moon” speech. Rice will host public events from September 10-12.

This partnership invites the university to host and attend presentations at Johnson Space Center, including its Gateway to Space lecture series, and to NASA personnel to present at and attend the Rice Space Institute’s Space Frontiers lecture series, the Professional Science Masters in Space Studies seminar series, and other events, per a release.

The university will also seek ways to involve NASA researchers as visiting scholars, share information that could lead to collaborations, encourage Rice students to seek NASA internships, and pursue opportunities to engage in bioscience and human health and performance research.

Vanessa Wyche presents a special plaque to Rice University. Photo by Jeff Fitlow/Rice University

Rice has collaborated with NASA since the agency’s inception, including donating land for what’s now Johnson Space Center, as well as founding the first space science department in an academic institution. Rice alums in space include Shannon Walker, who holds three Rice degrees; Peggy Whitson, who holds the American record for the most time in space; and Nichole Ayers, who joined the space corps last year, Rice notes.

In July 2019, veterans of the Apollo program reunited at Rice Stadium to toast the anniversary of the first moon landing (Apollo 11) and take part in a NASA video to mark the 50-year milestone.

“NASA’s Johnson Space Center has a long history of working with colleges and universities since the early days of the Mercury, Gemini and Apollo programs to help us achieve our human spaceflight missions,” said Vanessa Wyche, director of Johnson Space Center, in a statement. “We are eager to extend our partnership with Rice University to collaborate in vital research and technology development initiatives that will enable us to meet our nation’s exploration goals and advance human spaceflight as we work to land the first woman and first person of color on the moon under Artemis.”

Earlier this year, NASA also tapped University of Houston and Texas A&M University to expand partnerships at those institutions.

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This article originally ran on CultureMap.

Catch up on space news — from new partnerships at Rice University and the latest snub for the Space City. Photo via NASA.gov

Space City News: Houston passed over for military HQ, Rice forms new partnerships

aerospace updates

It's been a busy few days for space news, and in Houston — the Space City — it's all relevant to the continued conversation of technology and innovation.

With so much going on — from Houston being passed over for the Space Command's headquarters and Rice receiving $1.4 million in federal funds for a new hub — here's what you may have missed in space news.

The Ion awarded $1.4M to launch Aerospace Innovation Hub

The Ion will be home to the Aerospace Innovation Hub, thanks to a federal grant. Courtesy of Rice University

Through a partnership with NASA's Johnson Space Center and DivInc, The Ion has been awarded $1.4 million in federal funding to create its Aerospace Innovation Hub. The ASCI-Hub will support and develop regional minority business enterprises addressing aerospace-related challenges.

"Landing this award is another win for the region that leverages the unique strengths of the crewed space program at NASA JSC," says Jan E. Odegard, interim executive director of the Ion, says in a news release. "As Houston was critical to landing men on the moon in the late-'60s, the Ion's Aerospace Innovation Hub will be key not only to advancing the future of spaceflight, including the mission to Mars in the future, but also to tackling challenges facing our everyday lives here on Earth."

The hub will provide NASA's expertise and resources across robotics, medicine, health support systems, additive manufacturing, and more — as well as community events, education and training, and an accelerator program.

"We're eager to partner with the MDBA, Rice University and the Ion to help develop and grow minority entrepreneurs and accelerate innovative and tech-forward solutions in Houston," says Vanessa Wyche, deputy director of the JSC, in the release. "This partnership builds toward NASA's goals to enhance scientific and technological knowledge to benefit all of humankind and catalyze economic growth, as we propel commercialization of space and extend our presence in the solar system."

Opening in 2021, the Ion announced $1.5 million in grant funds in September. Those funds are going toward accelerators, which will collaborate with the Aerospace Innovation Hub.

"While we have taken many small — and valuable — steps over the past few years, this is one giant leap forward for our efforts to promote sustainable inclusion in Houston's entrepreneurial and technological ecosystem," says Christine Galib, senior director of programs at the Ion, in the release.

The Air Force announces 6 potential sites for Space Force base — and Houston misses the mark

Houston will not be considered for the Space Command HQ — but Texas isn't completely out of the running. U.S. Air Force Graphic by Rosario "Charo" Gutierrez

The United States Department of the Air Force announced the six candidate locations for the U.S. Space Command Headquarters — and Houston didn't make the cut.

The six locations include:

  • Kirtland Air Force Base in New Mexico
  • Offutt AFB in Nebraska
  • Patrick AFB in Florida
  • Peterson AFB in Colorado (where temporary operations are located)
  • Port San Antonio in Texas
  • Redstone Army Airfield in Alabama

The Air Force evaluated self-nominated cities from across 24 states based on factors related to mission, infrastructure capacity, community support, and costs to the Department of Defense, according to a press release. U.S. Space Command Headquarters location announcement is expected in early 2021.

"We are disappointed that Houston is not among the finalist locations for the U.S. Space Command," Susan Davenport, chief economic development officer for the Greater Houston Partnership, says in a statement to the Houston Chronicle. "We believe we put together a strong case for why Houston should be chosen. We will continue to work with the U.S. Air Force and other branches of the military on future opportunities and we will remain vigilant in our pursuit of aerospace industry opportunities for this region."

Rice Space Institute to collaborate with Canada

The Rice Space Institute has a new partner is Canada. Photo courtesy of NASA

Rice University's Rice Space Institute has signed a memorandum of understanding with the Consulate General of Canada in Dallas to collaborate on space science and technology.

The parties made the collaboration official at a virtual event on November 20. RSI Director David Alexander OBE, a Rice professor of physics and astronomy, says the partnership is key to the continued commercialization of space exploration.

"What's different about this agreement is that with the rapid growth of commercial space worldwide and the strength of the aerospace industry in Houston, it presents a new pathway for potential interactions between Canadian science and industry and commercial entities not just in the Houston region but around the world," he says in a news release. "It's a nice, complementary aspect to our connection with NASA."

The United States has collaborated with Canada on space exploration for decades, and Canada's government is committed to advancing space technology.

"This MOU with the Rice Space Institute comes at an exciting time in human space exploration," says Rachel McCormick, the Consul General of Canada in Dallas and Canada's official representative in the U.S. South Central region, in the release. "In 2019, the Government of Canada announced an investment of $1.9 billion over 24 years for the next generation of smart, AI-powered space robotics for the U.S.-led Lunar Gateway program.

"We are also providing $150 million over five years for the Lunar Exploration Accelerator Program," she continues. "LEAP will fund the development and demonstration of lunar science and technologies in fields that include AI, robotics and health."

From smart home technology to higher education institutions, these leaders are pushing forward innovation in Houston. Courtesy photos

3 Houston innovators to know this week

Who's who

Another week, another set of Houston innovators to keep your eye on. This week's edition crosses retail technology with higher education — both on this planet and beyond.

From tech that's orbiting the planet to tech that's in your very home, here are the Houston-based innovators to know.

Leah Barton, North American commercial director for Hive

Leah Barton oversees Hive's growing North American efforts from the Houston office. Courtesy of Hive

United Kingdom-based Hive, a smart product company, has bet on Houston as its battle ground for growth in the United States. The company recently tasked Leah Barton as North American Commercial Director to serve in the Houston office as of June 2019 and focus on this growth. Barton tells InnovationMap that she feels Houston is increasingly becoming an innovation hub.

"We know we've got the technical talent, we've got people who are interested in technology, whether it's from the medical angle, energy angle, aerospace angle," she says. Continue reading the story about Hive and Barton's plans for expansion by clicking here.

David Alexander, director of the Rice University Space Institute

David Alexander of the Rice University Space Institute says Houston's past accomplishments in space aren't all the Space City has to offer. Photo courtesy of Rice University

For David Alexander, director of the Rice University Space Institute, Houston's role in space exploration is far from over. In fact, even though it's been 50 years since Neil Armstrong phoned home to Houston from the moon, he argues that this moment is not all the Space City has to celebrate.

"In Houston, we tend to think of space as a destination, but it really is a resource," he says. "And we need to be thinking about it as a resource." Read the complete interview with Alexander by clicking here.

Paul Pavlou, dean of C. T. Bauer College of Business at the University of Houston

Paul Pavlou has been named as the dean of C. T. Bauer College of Business at the University of Houston. Courtesy of UH

Success is in the details for this new University of Houston C.T. Bauer College of Business dean, Paul Pavlou, who began his UH career earlier this month. Pavlou has a passion for higher education and the doors it has opened for him.

"My life was transformed by higher education," Pavlou says. "So, I feel the need to give back in terms of helping other students — especially of modest means like myself to do well in life and get a good job."

Pavlou has multidisciplinary efforts on his mind, as well as data and technology integration within the school's programs. To read more about Pavlou, click here.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

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