From space to marketplace

Houston medical devices company using NASA balancing technology prepares for commercial launch

Balancing is important throughout your life, and Zibrio has the tools and tips for you to use to stay centered. Pexels

In her postdoctoral work at NASA, Katharine Forth and her colleague were tasked with finding a new way to track the balance of astronauts on the moon.

"The machines typically used for balance measurement can be as large as a telephone booth, so we invented a new way to measure postural control using a much smaller mechanism that fit inside a moon boot," Forth says.

She didn't know it at the time, but working on this technology would lead her to create Zibrio, The Balance Company with her colleague, Erez Lieberman Aiden.

Zibrio is a health company that aims to be the gold standard of measuring balance. The Zibrio scale calculates users' weight like a typical scale and rates their balance on scale of 1 to 10.

The scale gathers data from your weight, your postural control, your muscles and other factors to calculate the rating. Andrea Case-Rogers, chief experience officer at Zibrio, describes a perfect rating of 10 as elusive for most, or "Simone Biles on a good day."

After seeing their rating, users can identify any problems and start taking steps to improve their balance. Zibrio will also come with a smartphone app, so users can track their balance, any fluctuations and progress over a long-term period.

By using the scale and app together, users can gain a greater understand of what in their lifestyle is helping versus hurting their balance.

From space to the marketplace
After co-founding Zibrio together in 2015, Forth and Aiden have taken the company a long way since then.

Zibrio is a finalist for the 2019 SXSW Pitch in the health and wearables category. In 2015, the company was part of the Texas Medical Center's TMCx medical devices cohort. Both programs highlight the innovative technology being used as well as the big impact that Zibrio could have for both consumers and clinicians.

Zibrio already has conducted clinical trials all over Houston by working with Memorial Hermann and UT Physicians, and the company is currently focused on fundraising. Forth and her team of five will use these funds to get the scale and smartphone app consumer-ready and launched.

The commercial launch for both the scale and app is planned for later this year.

"We're currently finalizing the design with the manufacturer, so they can make the scale available commercially," Forth says. "Since 2015, we've been fundraising, building prototype scales and conducting clinical trials."

Finding balance at any age
A common misconception is that our balance deteriorates in older age. In actuality, a lifetime of behavior and activity affects our balance in later years. Falls are the leading cause of accidental death and unexpected injuries in older adults.

"If you have been mostly sedentary your whole life, by the time you hit your later years, your lower limb strength is weakened affecting your ability to move." Forth says, "so many factors feed into your balance, which means there are so many things that can be done to lower your fall risk."

When Forth and her team ran a balance program at a senior living facility, they halved the number of falls in two years. By creating an awareness of balance, they were able to drive changed behaviors in the seniors, in turn, improving their balance.

According to Case-Rogers, Zibrio is bringing the balance conversation to people in 60s and 70s who want to keep their lifestyle and not deal with mobility and health issues later. They want to show investors that there is a market for wellness product like Zibrio among older people.

Zibrio will sponsor the National Senior Games, the largest multi-sport competition for seniors in the world, this summer in Albuquerque. With over 10,000 athletes, Forth and her team are excited to introduce Zibrio to a larger audience.

Forth firmly believes balance measurements should be a part of routine wellness exams and home self-monitoring, especially in later years.

"When athletes stand on a scale and see their number, it's like a light goes on in their heads and they realize how important balance is," says Forth. "That's what I love, we have this great product that opens up the conversation about and is really helping people in middle age and beyond."

The next TMCx cohort begins August 5. Courtesy of TMC

The Texas Medical Center's startup accelerator, TMCx, has added 19 companies from all around the world to join its medical device family.

The TMC Innovation Institute team narrowed down 140 applications to 40 for the second round of the process, which includes face-to-face interviews, according to a release. After those, 18 companies were selected to join the TMCx09 class, which focuses on medical devices. The last cohort, which specialized in digital health, concluded on June 6.

Out of the 18 companies, five are from Houston. Four other startups hail from other corners of the United States, while 10 international companies also made the cohort. The program commences on August 5, and will run for four months before concluding in a demo day event in November.

Here are the medical device startup companies joining the TMCx09 cohort.

See update at the bottom of this story.

Vascular devices

  • Neurescue (Copenhagen, Denmark) — Neurescue has developed a computer-aided aortic occlusion catheter to help save the lives of patients in the emergency care setting.
  • Venari Medical (Galway, Ireland) — Venari Medical is developing BioVena — a medical device that treats varicose veins and venous leg ulcers with a minimally invasive approach intended to reduce pain.
  • Obsidio (Solana Beach, California) — Obsidio is developing a universal gel embolic material to shrink lesions or to treat internal bleeds, aneurysms and vascular malformations.

Novel therapies

  • PATH EX (Houston) — PATH EX is developing an extracorporeal blood cleansing device designed to selectively remove pathogens, including multi-drug resistant bacteria, and endotoxins from circulating blood to diagnose and treat sepsis.
  • Innosphere (Hafia, Israel) — Innosphere is a medical device company developing brain stimulation solutions for treating cognitive disorders, with a focus on ADHD.

Rehab

  • AbiliTech (St. Paul, Minnesota) — AbiliTech is restoring independence to patients with upper limb neuromuscular conditions by offering a wearable assistive device that allows the user to perform independent activities of daily living.
  • Komodo OpenLab (Toronto, Ontario, Canada) — Komodo OpenLab has developed Tecla, an assistive device giving individuals with physical disabilities the ability to communicate, control, and connect with the world.

Surgery

  • CNX Medical (Houston) — CNX Medical is developing a transcutaneous neurostimulator that is placed in the ear and helps reduce inflammation after abdominal surgery, with a focus on post-operative ileus.
  • CorInnova (Houston) — CorInnova has developed a soft robotic non-blood contacting biventricular cardiac assist device for the treatment of heart failure that would eliminate the many adverse events associated with current technologies.
  • Ictero Medical (Houston) — Ictero Medical is developing a minimally invasive ablation solution to treat high-risk patients with gallstone disease and offer patients the benefits of surgery without the risk. The company was among the big winners at the Texas A&M New Ventures Competition.

Diagnostics

  • Artidis (Basel, Switzerland) — InArtidis has developed a nanomechanical biomarker technology using precise tissue measurement in combination with data analytics to personalize cancer diagnosis.
  • Inveox (Munich, Germany) — Inveox automates the pre-analytical process in cancer diagnosis to improve patient safety and lab efficiency.
  • Cambridge Respiratory Innovations Ltd. (Cambridge, United Kingdom) — CRiL has developed, N-Tidal, a device that analyzes CO2 end-tidal breathing to improve respiration monitoring.

Toward home health

  • Kegg (San Francisco) — Kegg is on a mission to simplify every woman's journey towards taking charge of her fertility with a user-friendly monitoring device.
  • TestCard (London) — TestCard is a flat pack urine test kit that functions in combination with a mobile phone application, turning a phone's camera into a clinical grade scanner.
  • Patch'd (New South Wales, Australia, and San Francisco) — Patch'd uses deep learning and wearable devices to predict the onset of sepsis in the at-home patient.

Transplant

  • Volumetric (Houston) — Volumetric's 3D bioprinting platform creates materials with living cells with applications in biomaterials, cancer research, and eventually human organ replacements. The company's technology started out of Rice University.
  • Tevosol (Edmonton, Alberta, Canada) — Tevasol is developing organ transplant transportation solutions. Their portable warm perfusion machines will help surgeons transplant more organs today and solve organ shortage tomorrow.

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Diagnostic Photonics withdrew from the program after the article published.