Van Heron Labs, founded at TMC, raised a $1.1 million seed round led by FoodLabs. Photo via Getty Images

A biotech company that was founded at the Texas Medical Center in Houston has raised fresh funding to support its goal of innovating new technologies for a healthier humanity.

Van Heron Labs, based in Huntsville, Alabama, raised a $1.1 million seed round led by FoodLabs, a European investor and venture studio for food, health, and climate. The startup taps into genomics, bioinformatics, artificial intelligence, and nanotechnology to improve how cells are cultured and harnessed with the mission to address critical industrial and global challenges with biotechnology.

“Van Heron Labs looks forward to using the generous support and funding from FoodLabs to advance our goal of making biological innovation better, faster, and cheaper," Rebecca C. Vaught, founder and CEO of Van Heron Labs, says in a news release. "By fueling the new bio-economy, we feel that our customers can optimize their systems and bring technologies to overcome critical global challenges to market."

Van Heron Labs, which was founded by Vaught, Alec Santiago, and Nithin Parsan in February 2020, originally launched with its cell-focused platform to support COVID-19 pandemic response. The company's cell-based applications also include cancer therapeutics and food and materials production.

“We are excited to lead the funding round in Van Heron Labs, as we firmly believe that their innovative approach to optimizing cellular nutrition has the potential to revolutionize multiple industries, including biopharma, biomanufacturing, foodtech, and agriculture,” Julius Strauss, investor at FoodLabs, says. “We are excited to be partnering with Dr. Rebecca Vaught and her team as they continue to push the boundaries of innovation in the bio-economy.”

The funding will go toward supporting existing and new product lines.

Van Heron Labs' automated flagship platform uses bioinformatics and advanced AI tools to discover the optimal cellular fuel. This information can be used to personalize the customers’ culture media to provide more excellent quality, efficiency, and scalability, per the company.

Co-founded by CEO Jessica Traver, IntuiTap says it plans to roll out the device at U.S. hospitals within the next year. Photo courtesy of IntuiTap

Houston health tech startup revolutionizing spinal taps receives FDA clearance

tap in

Houston startup IntuiTap Medical has gained clearance from the U.S. Food and Drug Administration for its VerTouch medical device.

The company says VerTouch is designed to make spinal punctures more accurate and consistent. The handheld imaging tool helps health care providers perform spinal punctures at a patient’s bedside.

IntuiTap says it plans to roll out the device at U.S. hospitals within the next year. The company is mulling global partnerships to help launch VerTouch.

IntuiTap’s proprietary spinal-mapping technology enables VerTouch to generate a 2D image of lumbar spinal anatomy, helping health care providers visualize a patient’s spine and guide them toward more precise needle placement.

Each year, 12.7 million Americans undergo an epidural, spinal block, or lumbar puncture, says IntuiTap.

“Having spent more than two decades pioneering the use of ultrasound to improve emergency lumbar punctures, I know the challenge of these procedures and that difficult training and image interpretation prevent ultrasound from being a complete solution,” Dr. Michael Blaivas, co-founder past president of the Society of Ultrasound in Medical Education, says in a news release.

IntuiTap says the FDA clearance “validates the safety and effectiveness” of VerTouch. The device has undergone testing at several institutions in the U.S., including Houston’s Texas Medical Center and Chicago’s Northwestern Memorial Hospital.

Jessica Traver, co-founder and CEO of IntuiTap, says the FDA clearance “marks a crucial milestone in our team’s journey to making epidurals, spinals, and lumbar punctures more accurate and efficient.”

Investors in IntuiTap include:

  • Dr. Paul Klotman, president of the Baylor College of Medicine
  • Venture capitalist Tim Draper
  • William Hawkins III, retired CEO of medical device giant Medtronic
  • Dr. Vip Patel, Founder of the Global Robotics Institute
  • Dr. Mary Klotman, dean of the Duke University’s medical school
  • Carrie Colbert, founder of Houston-based Curate Capital, a female-focused VC firm

“Our investment in IntuiTap was just as much about our faith in the technology, our faith in Jessica as the founder, and our conviction that innovation was sorely needed in this area,” Colbert says.

“The fact that the company is receiving FDA clearance is a huge leap forward, and as a venture capital fund who focuses on female-founded companies that benefit women, it’s extremely rewarding to know this device will impact so many women’s lives.”

In 2021, IntuiTap announced it had closed a $5.5 million series A funding round led by Curate Capital and The Pink Ceiling, a woman-centered investment firm. The startup was founded in 2016.

Houston Methodist's cardiovascular sciences, orthopedics and RNA therapeutics research programs will be the first to occupy the new space. Photo via houstonmethodist.org

Houston Methodist signs on at new TMC Helix Park building

moving in

Texas medical giant Houston Methodist is the latest to join the Dynamic One building within TMC Helix Park.

The hospital announced that it has signed a 75,800-square-foot lease in the building and will take over two floors of biomedical research laboratories. Houston Methodist's cardiovascular sciences, orthopedics and RNA therapeutics research programs will be the first to occupy the space.

“We are always focused on translating innovative medical discoveries into viable therapies for patients. These highly entrepreneurial programs, which translate these discoveries to the bedside, are a natural fit within the emerging biotechnology ecosystem that the TMC is cultivating,” Edward Jones, president and CEO of Houston Methodist Research Institute, said in the announcement.

Houston Methodist joins anchor tenant Baylor College of Medicine in the state-of-the-art building, which opened in Nov. 2023.

The 12-story Dynamic One building features lab space, offices, restaurants, and stores. It represents the first of four buildings planned for the 37-acre TMC Helix Park and was one of the largest life sciences projects in the U.S. set to come online last year.

Developers are slated to open three more move-in-ready Beacon Ready Labs in the building this summer, ranging from 9,000 to 15,000 square feet.

“We are excited to welcome Houston Methodist to this space; their commitment to bench to bedside innovation and track record of transformative new discoveries aligns with our vision for the campus,” William McKeon, president and CEO of the Texas Medical Center, said in a statement. “Beacon Capital has been an outstanding partner in the development of TMC Helix Park, lending their insights to our efforts to design a campus that would seamlessly blend institutions and industry.”

TMC Helix Park officially opened last October with the launch of the TMC3 Collaborative Building. The 250,000-square-foot building anchors the campus and houses research initiatives from the four founding partners: Texas Medical Center, The University of Texas MD Anderson Cancer Center, Texas A&M University Health Science Center, and The University of Texas Health Science Center at Houston.

UTHealth Houston also broke ground on its 350,000-square-foot tower on the campus last summer. It's slated to open in time for the 2026 Fall semester. And TMC unveiled plans for the fourth and final component of Helix Park, the TMC BioPort, in 2022.

A Houston company with a promising immuno-oncology is one step closer to delivering its cancer-fighting drug to patients who need it. Photo via Getty Images

Houston immuno-oncology company reaches next FDA milestone, heads to phase 2 trial

green light

A Houston immuno-oncology company has recently made major headway with the FDA, including both a fast track and an orphan drug designation. It will soon start a phase 2 trial of its promising cancer fighting innovation.

Diakonos Oncology was born in 2016, the brainchild of Baylor researchers already hard at work in the realm of dendritic cell vaccines. Drs. Will Decker, Matt Halpert, and Vanaja Konduri partnered with Dan Faust, a Houston businessman and pharmacist, to bring their treatment to the public, says COO Jay Hartenbach.

The name Diakonos means “deacon or servant in Greek,” he explains. “A lot of companies end up focusing on treating a specific disease or cancer and what you end up having is a significant amount of potential but with a lot of tradeoffs and downsides. And so our goal is we need to eliminate the cancer but we can't harm or dramatically malign the patient in doing so.”

How do they do that? Because the therapy catalyzes a natural immune response, it’s the patient’s own body that’s fighting the cancer. Hartenbach credits Decker with the idea of educating dendritic cells to attack cancer, in this case, glioblastoma multiforme (GBM), one of the most aggressive cancers with which doctors and patients are forced to tangle.

“Our bodies are already very good at responding very quickly and aggressively to what it perceives as virally infected cells. And so what Dr. Decker did was basically trick the immune system by infecting these dendritic cells with the cancer specific protein and mRNA,” details Hartenbach.

Jay Hartenbach is the COO of Diakonos Oncology. Photo courtesy of Diakonos Oncology

But GBM isn’t the only cancer on which Diakonos Oncology has its sights set. Other notably stubborn-to-treat cancers that they’re working on include pancreatic cancer and angiosarcoma. The scientists are focused on meeting unmet medical needs, but also realize that treating such cancers would allow for the fastest determination of whether or not the treatment was effective.

The fast track designation, originally received last fall, means that the drug approval time for DOC1021, Diakonos’ glioblastoma vaccine, will be only six months. But Hartenbach highlights an additional boon, the fact that the special designation also allows for more frequent communications with the FDA.

“That’s very helpful for us, right as we're contemplating how to design the upcoming trials. From a business standpoint, it also is incredibly helpful because it provides a third party validation of what we're doing and the results that we're seeing,” he says.

What they’re seeing includes the survival of 13 out of 16 patients from the initial October 2021 enrollment. The three patients who passed away received the lowest dose of DOC1021. Hartenbach says that the remaining patients are thriving, with no serious adverse effects. With a median survival rate of 15 to 21 months, it’s hard to understate the significance of these patients’ success.

Diakonos Oncology is headquartered in Houston, with a staff of 10 in Space City and an additional eight distributed employees. Hartenbach says that the company’s hometown has been instrumental in its success. He mentions that the robust innovation of the Texas Medical Center meant that as the company has grown, there has never been a motivation to leave Houston.

“You're having a lot of both investment and companies actually moving to Houston,” Hartenbach says. “So we’ve been fortunate to have started there. There are bigger traditional biotech hubs, San Diego, Boston, and San Francisco, but Houston really is now putting itself on the map and it's getting a lot of attention.”

One of the companies responsible for that improved reputation? Diakonos Oncology and its promising approach to aggressive cancers.

Portal Innovations announced that Monique Knighten as an executive director in Houston. Photo via LinkedIn

Chicago life science innovation firm names Houston leader

who's who

After announcing its expansion into Houston last summer and opening its office in a new Texas Medical Center building, Portal Innovations has named its Houston leader.

Portal Innovations announced that Monique Knighten as an executive director in Houston in a LinkedIn post this week. She has over 15 years of experience in supporting research scientists and clinicians working to develop therapeutics in labs and clinics. According to her LinkedIn, she's served in the position since November.

Prior to her new role at Portal, Knighten worked as a manager level at Sartorius Stedim in Houston for five years. Before that role, she served as a technical sales consultant in Texas at Miltenyi Biotec, primarily in the immuno-oncology therapeutic market in the TMC.

Portal first announced its expansion into Houston in June of last year.

“Houston is one of the fastest-growing cities in the U.S., and home to one of the world’s leading cancer research institutions, The University of Texas MD Anderson Cancer Center,” Portal’s Founder and CEO John Flavin said at the time. “It’s critical for us to open in Texas and leverage nearby pipelines from Rice University, UTHealth Houston, Texas A&M, University of Houston, Baylor College of Medicine, and others across Houston’s innovative life sciences ecosystem. We’re thrilled to work with TMC to help grow tomorrow’s biotech and medtech leaders.”

Portal's local office is in the Helix Park complex's Collaborative Building, which opened in October. Helix Park is a 37-acre mixed-use campus currently under construction. The institutional agnostic, 250,000-square-foot building will anchor Helix Park and house research initiatives from the four founding partners: Texas Medical Center, The University of Texas MD Anderson Cancer Center, Texas A&M University Health Science Center, and The University of Texas Health Science Center at Houston.

Flourishing Nexus recently won runner up in the innovation category of the city's Liftoff Houston competition. Photo courtesy of the City of Houston

Houston startup's AI-driven networking and education platform to soft launch in TMC

going online

Connecting medical professionals is about to get easier thanks to a new Houston company, Flourishing Nexus.

Next month, their digital platform, The Nexus, will debut to in a soft launch to a curated group of TMC employees.

“Think of it as a combination of existing platforms like LinkedIn, providing professional networking; Khan Academy, which provides excellent training and education; and a collaborative workspace like Google Workspace or Microsoft Teams, all enhanced by AI,” says Diane Nguyen.

Nguyen is a pharmacist by training, while her co-founder, Satid Thammasitboon, is an MD and master in health professions education.

The pair began working together in the health professions education space three years ago, but only established Flourishing Nexus in July of 2023. The company’s moniker refers to the concept of human flourishing.

“Our mission would be to promote human flourishing among health professionals,” says Thammasitboon.

The concept of human flourishing traces back at least to Aristotle, but The Nexus’ understanding of it is based on psychologist and educator Martin Seligman’s PERMA theory. The mnemonic stands for Positive Emotion, Engagement, Relationships, Meaning, and Accomplishment.

“We endeavor to bring these concepts of PERMA and human flourishing into the health professions space,” says Nguyen.

“Often our healthcare organizations or industries, when they hear health professionals are having issues with burnout, the response or reaction would be to increase incentive, financial support, or professional development to enhance resilience,” adds Thammasitboon. “We search for meaning we want to make a difference in the life of another rather than ‘everything is all about money.’”

Both professionals have globe-spanning careers. Thailand native Thammasitboon says that his endeavors have taken him across Europe, Southeast Asia, and East Asia, while Nguyen’s work has focused her attention on South America, sub-Saharan Africa, and Eastern Europe.

“I realized that the key to providing better outcomes and health care for the patients was really dependent on the continuing education and training of the staff,” Nguyen says.

Those experiences proved to be the roots from which The Nexus grew.

But the team’s colleagues abroad won’t be among the first The Nexus users. That distinction will belong to Houston’s rich community of medical pros. And when the platform soft launches in January, it will be with two awards already under its belt.

The Liftoff Houston Startup Business Plan competition took place last month. Nine finalists, mostly entrepreneurs from underrepresented backgrounds, were selected from among 100 applicants to compete in Liftoff’s Pitch Day. Not only was The Nexus among those competitors, it raked in a runner-up prize, as well as fan favorite in the innovation category.

Nguyen, who did the pitching, says that Liftoff helped Flourishing Nexus tremendously with both its preparation workshops and feedback from the judges.

“Sometimes you think you have a great idea but it’s not until you critically think about your own plan, analyze your plan, and prepare to pitch it that you really learn about it. This preparation helped us and strengthened our mission. Our business plan is much better,” says Thammasitboon.

Next up? Launching and growing The Nexus’ community. Nguyen also says they plan to participate in more competitions, including possibly Houston Community College’s Business Plan Competition. It’s one more way of bringing the abstract concept of human flourishing to a flesh and blood audience.

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Houston expert: How you should be approaching recruiting in 2024

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The January jobs report, per BLS, may be cause for celebration with 353,000 new jobs, but with a low unemployment rate of 3.7 percent, the tight labor market persists.

The same report states there were 2,000 more jobs in oil and gas extraction in January. Finding the right people for energy jobs can be a challenge right now as the industry has experienced flux the past few years. Many energy employers find key talent has moved into new industry verticals, drawn by the promise of increased stability.

Recruiting in the tech and energy sectors may be challenging, but the right candidates are out there. It is important for hiring managers to be realistic as they approach recruiting and hiring timeframes and make smart hiring decisions. The organization will be better off in the long run for this approach.

The following recruiting strategies are poised to support energy employers throughout the year.

Get personal.

Job candidates want to feel like their future employer is genuinely interested in them, which means recruiters should personalize the candidate’s experience. This starts by taking a holistic look at the hiring funnel and considering ways to make each candidate feel as though they are the only one you are talking to for the role.

Each touchpoint impacts how the candidate perceives the organization. The job description should inspire candidates, making them excited to apply and motivating them to dream about a future with your organization. Personalizing recruitment outreach messages to speak to their individual talents instead of a standard, generic message speaks volumes.

Moving through the hiring process as quickly as possible is important, but recruiting is about the long game. There are candidates who fall into place in a matter of days. Other times, you may have a conversation with a candidate months or even years before the timing is right for them to make a move. Asking about the candidate’s professional timeline and letting them know that you are willing to work with them, no matter how fast or slow, makes them feel special and valued by your company.

Be ready to compromise.

It has become hard to find the right fit for some of the energy jobs today. However, this does present an opportune moment for employers to reassess the conventional prerequisites typically required for specific positions. Criteria such as an exact college degree, a specified number of years of relevant experience, industry-specific expertise, an unbroken work history and proficiency in specific software applications are areas to reconsider in the job postings, job descriptions and interviews. This strategic adjustment broadens the talent pool and provides access to individuals whose suitability for a role might have been overlooked. Shifting away from stringent education backgrounds and narrowly defined experience, and instead prioritizing qualities such as adaptability and learning capabilities in the search for candidates, recruiters may discover a smoother path to securing qualified candidates.

Grow internal talent.

Recruitment today also means recruiting internally. The optimal approach to efficiently filling positions is promoting the role internally as existing employees have a vested interest and are deeply ingrained in the company’s culture. Their familiarity with colleagues, procedures and protocols facilitates a swift transition into new roles. In order for this to become a possibility, it’s imperative for leaders to nurture internal talent through professional development initiatives that equip employees with the skills needed for advancement. Tailored learning opportunities, mentorship and guidance for reskilling and upskilling can foster internal mobility, enhance employee retention and ensure sustained success. With all this in mind, recruiters should keep in close contact with management teams to discuss internal candidates and their career path.

There is no one way to recruit in 2024, but focusing on the individual and their skills as well as in-house candidates can make it a successful endeavor.

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Jill Chapman is a director of early talent programs with Insperity, a leading provider of human resources and business performance solutions.

Houston software shop bets on AI with new C-suite member

eyes on AI

A Houston-based software company has named its first chief artificial intelligence officer.

Blue People has named Luis Arregoces as the company’s CAIO. With 20 years of experience, Arregoces has led AI projects for global Fortune 100 companies in various industries.

He has a Ph.D. in Economics from the University of New Mexico and is an adjunct professor in Statistics and Data Science at the University of Houston. He previously led the Applied Intelligence and Data Science at Accenture's Innovation Hub.

“We are beyond excited to have Luis on board,” Alfredo Arvide, chief innovation officer of Blue People, says in a news release. “His leadership and vision will allow Blue People to help clients and C-level executives develop AI roadmaps and solutions for real-time analytics, secure data sharing, and technology-agnostic ecosystems that will shape the future of innovation across all industries in Houston and throughout the region.”

Blue People has offices in Houston, Austin, Texas, and Monterrey, México. Blue People was named People’s Choice: Startup of the Year at the 2023 Houston Innovation Awards. The company also recently participated in CodeLaunch Houston, where its startup partner won the judges' pick in the competition.

“I am honored to join Blue People and be a part of this historic moment,” Arregoces says in a news release. ”Together, we have the opportunity to shape the future of AI in Houston and beyond. AI’s versatility and transformative potential make it indispensable across all industries to drive innovations, efficiency, and competitiveness.”

Houston surgeon takes part in first-of-its-kind surgery in space

remote control health care

A small surgical robot at the International Space Station completed its first surgery demo in zero gravity last week, and one of the surgeons tasked with the remote robotic operations on simulated tissue was Houston-based Dr. Theodoros Voloyiannis.

Voloyiannis took part in what is being referred to as “surgery in space” by being one of the six doctors remotely controlling spaceMIRA — Miniaturized In Vivo Robotic Assistant — that performed several operations on simulated tissue at the lab located in the space station. The surgeons operated remotely from earth in Lincoln, Nebraska. The remote surgeons worked to control the robot's hands to provide tension to the simulated tissue made of rubber bands. They then used the other hand to dissect the elastic tissue with scissors.

“I said during the procedure ‘it was a small rubber band cut, but a great leap for surgery,’“ Voloyiannis tells InnovationMap. “This was a huge milestone for me personally in my career.”

The robot was developed by Virtual Incision Corporation, and made possible through a partnership between NASA and the University of Nebraska. The team of surgeons took part in a demonstration that is considered a common surgical task, as they dissected the correct piece of tissue under pressure.

Latency is the time delay between when the command is sent and the robot receives it, and that was the big challenge the team faced. The delay was about 0.85 of a second according to what the colorectal surgeon who worked on spaceMIRA Dr. Michael Jobst said to CNN. The demo overall was a success according to the team, and posed a new-found adrenaline rush due to the groundbreaking innovation.

“The excitement of the new and the unknown,” Voloyiannis says on the feeling of doing the first operation of its kind. “I never thought I’d be doing something like this when I was in training and in medical school.”

Voloyiannis serves as the chairman of colon and rectal surgery for The US Oncology Network. He was chosen for this experiment due to his experience and expertise performing robotic colorectal surgery. Voloyiannis and the developers are hopeful that this type of technology will soon allow doctors to perform this specialized robotic surgery on patients living in rural areas without a specialized surgeon nearby, military battlefields, as well as regularly in space one day.

“The same concept of remote surgery regularly in space could certainly be entertained,” Voloyiannis says. “When you do things with an absence of gravity and perform a surgery in that environment — of course that changes the way we do things. When you have an absence of gravity with bodily fluids, it is a very hard surgery, but with partial gravity that idea can be entertained.

"Remotely, internet connectivity would have to be considered and you’d have someone remote like me here, while potentially there you’d have someone with less training doing the procedure there guiding the robot," he continues. "It’s quite the concept though.”

The doctors had to account for nearly a second of delay in connectivity. Photo courtesy of Texas Oncology