The future is now

5 Houston biotech companies taking health care to new levels

With the Texas Medical Center in their backyard, these Houston biotech companies are creating breakthrough technologies. Getty Images

Houston is the home of the largest medical center in the world, so it comes as no surprise that the Bayou City is also home to breakthrough technologies. Here are five Houston companies developing some of this biotech advancements.

Moleculin Biotech Inc.

Houston-based Moleculin has three different oncology technologies currently in trials. Getty Images

Immunotherapy and personalized medicine get all the headlines lately, but in the fight against cancer, a natural compound created by bees could beat them in winning one battle.

In 2007, chairman and CEO Walter Klemp founded Moleculin Biotech Inc. as a private company. The former CPA had found success in life sciences with a company that sold devices for the treatment of acne. That introduction into the field of medical technology pushed him toward more profound issues than spotty skin.

"Coincidentally, the inventor of that technology had a brother who was a neuro-oncologist at MD Anderson," Klemp recalls.

The since-deceased Dr. Charles Conrad slowly lured Klemp into what he calls the "cancer ecosphere" of MD Anderson. In 2016, the company went public. And it looks like sooner rather than later, it could make major inroads against some of the toughest cancers to beat. Read the full story here.

Cavu Biotherapies

Dr. Colleen O'Connor has adapted immunotherapy treatments to be used in dogs. Courtesy of CAVU Biotherapies

Breakthrough biotech doesn't have to just be for humans. More than three years after its founding, Houston-based veterinary biotech company CAVU Biotherapies' had its first cancer patient: a black Labrador in Pennsylvania diagnosed with B-cell lymphoma.

Dr. Colleen O'Connor, CEO and founder of CAVU Biotherapies, established the company in July 2015 with a goal to help pets live longer post-cancer diagnoses. O'Connor, who earned a PhD in toxicology with a specialty in immunology, has more than a decade of hands-on experience researching cancer treatments.

"Our goal is to scale up and be able to increase our dogs' qualities of life with us," O'Connor said. "We want to keep families intact longer and we want to be able to modernize cancer care for our animals." Read the full story here.

Innovative Biochips

iBiochips, led by founder Lidong Qin, was awarded a $1.5 million grant in September to help develop a new technology that delivers data about the cell's genetic makeup and reports abnormalities. Courtesy of Lidong Qin

Innovative Biochips, a Houston-based biotechnology company, is one step closer to commercializing technology that the company hopes will provide an opportunity for researchers to detect diseases earlier.

The company was founded three years ago by Dr. Lidong Qin, a professor at the Houston Methodist Research Institute's department of nanomedicine. He launched iBiochips as an independent faculty startup that licensed technology from Houston Methodist. Qin says he wanted to engineer and manufacture devices that focus on revolutionizing single-cell isolation and genetic analysis. Read the full story here.

Celltex

Celltex's stem cell technology has received positive results from its multiple sclerosis, Parkinson's, and rheumatoid arthritis patients. Courtesy of Celltex

A Houston stem cell company is making strides in regenerative medicine. Celltex's treatment has been proved effective with its patients. Eighty-three percent of multiple sclerosis patients have reported improvement of symptoms specific to their disease, as have 73 percent of Parkinson's sufferers. But the staggering fact is that 100 percent of 58 respondents with rheumatoid arthritis say they have benefited.

David Eller, chairman, co-founder and CEO of the company, also recently announced the company's expansion to Saudi Arabia. Read the full story here.

Ridgeline Therapeutics

Houston-based Ridgeline Therapeutics isn't going to allow you beat aging, but someday it may well help you to live without muscle loss or diabetes. Getty Images

Stan Watowich pictures a world where elderly people have the same healthy muscles they had at a younger age. Watowich is CEO of Ridgeline Therapeutics, a spin-off company of the University of Texas Medical Branch in Galveston where he is an associate professor of biochemistry and molecular biology, and he wants to make it clear that he is not going to cure aging.

"You and I are still going to get old," he says. "But we have our hopes that as we get old our muscles will stay healthy."

He's talking about the drug candidate, RLT-72484. It has been shown to reactivate muscle stem cells and regenerate skeletal muscle in aged laboratory mice. Read the full story here.


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Building Houston

 
 

Here's what startups took home wins at CERAWeek. Photo by Natalie Harms/InnovationMap

Over 200 startups participated in CERAWeek this year, and 18 of those companies pitched at a Greater Houston Partnership event.

The Houston Energy Transition Initiative, an initiative to promote Houston's work within the energy transition, hosted its second annual HETI Energy Ventures Competition at CERAWeek Innovation Agora. The competition was divided into four categories. The first batch of startups consisted of five companies from the Texas Entrepreneurship Exchange for Energy, or TEX-E, a collaboration with Greentown Labs, MIT’s Martin Trust Center for Entrepreneurship, and universities across Texas.

The winning startups shared $50,000 of prizes, sponsored by TEX-E. Houston-based Helix Earth Technologies — which has developed high-speed, high-efficiency filter systems derived from technology originating at NASA — won both the first place prize and fan favorite for the category. Helix's co-founders, Rawand Rasheed and Brad Husick from Rice University, walked away with $25,000 in prizes

Founded by Bryon Praslicka, Daniel Zamarron, and Craig Newman from Texas A&M University, Flux Works LLC, and its magnetic gear technology, took second place and $15,000 home. Tierra Climate, a two-sided marketplace for carbon offsets and other sustainability efforts founded by Emma Konet and Jacob Mansfield from Rice University, won third place and $10,000.

Helix Earth Technologies walked away with the top prize of the TEX-E category. Photo via greentownlabs.com

The next sets of startup pitches we broken down by funding stages — pre-seed and seed, series A, and series B and beyond.

Red Shift Energy, uses plasma energy to produce hydrogen from hydrogen sulfide, won fan favorite in the pre-seed and seed category sponsored by HX Venture Fund. A member of Halliburton Labs, the company also was recognized as Chevron favorite.

Per the judging panel, CanaGas won the title of most promising in the pre-seed and seed category sponsored by Alchemy Industrial. The Canadian company liquifies natural gas without costly cryogenics or stripping of the gas.

Houston-based Criterion Energy Partners won both the most-promising series A company category sponsored by SLB, but also the fan favorite series A category sponsored by Guerrella LLC. A geothermal energy tech company, Criterion was also a member of Rice's inaugural Clean Energy Accelerator cohort.

OptiSeis Solutions also won in both categories for the series B track. The company, a geophysical acquisition design and software company, won the title of most promising in the series B category sponsored by Pana LCE Investments and the series B fan favorite category sponsored by Halliburton Labs.

Lastly, the competition named the Most Impactful DEI, a category sponsored by Pana LCE Investments. Austin-based Gazelle Ecosystems, a social innovation startup with eco-solutions for corporations, won that category.

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