digital disease detective

Houston-based biotech company aims to revolutionize cellular dissection technology

iBiochips was awarded a $1.5 million grant in September to help develop a new technology that delivers data about the cell's genetic makeup and reports abnormalities. Getty Images

Innovative Biochips, a Houston-based biotechnology company, is one step closer to commercializing technology that the company hopes will provide an opportunity for researchers to detect diseases earlier.

The company was founded three years ago by Dr. Lidong Qin, a professor at the Houston Methodist Research Institute's department of nanomedicine. He launched iBiochips as an independent faculty startup that licensed technology from Houston Methodist. Qin says he wanted to engineer and manufacture devices that focus on revolutionizing single-cell isolation and genetic analysis.

Qin says it can be difficult to launch a biotech startup in Houston, since the industry requires hefty initial funds to open a facility, get patents and hire a team of researchers.

"In the Houston area, even though it looks like it's a lot of state money (grants) around, it's very limited, and that's been a challenge of ours," Qin says.

But with the help of a $1.5 million investment from a private investor, Qin was able to launch iBiochips in 2015, and shortly after opened his own lab on Kirby Drive.

Recently, iBiochips was awarded a $1.5 million grant in September from the National Institutes of Health's Small Business Technology Transfer program. The grant will further support the company's research and development of an automated yeast dissection chip, which is designed to perform a raw analysis of single cells and deliver data about the cell's genetic makeup and report abnormalities.

Prior to the phase two grant, iBiochips was also awarded NIH's phase one grant of $225,000 in September 2017 to develop a prototype for the company's flagship cell isolation product, the Smart Aliquotor.

The Smart Aliquotor is a single-cell isolation dissection platform that allows scientists to analyze larger amounts of cells at a much faster rate than traditional isolation methods, Qin says. He says the system is also more convenient for researchers to operate because traditional cell isolation techniques require a lot of human effort.

To isolate the cells with a Smart Aliquotor, a scientist would take a patient's blood sample and inject it into a single point in the device. The blood sample would then travel through microfluidic channels into the device's 60 to 100 isolated holes, Qin says.

"In three days, we can handle about one million cells," Qin says. "In a traditional approach, people can handle only one or two cells in three days. So that is how we came to the [idea of the] chip can help a scientist do 20 years of work in three days."

The Smart Aliquotor can then be examined with iBiochips' newly funded automated dissection chip, which Qin says has the potential to detect cancer or infectious diseases earlier than before.

"If you isolate a cell by itself — even in the very beginning stage when the aggressive cells are not as dominating yet — you can still see that [abnormality in the sample]," Qin says.

iBiochips' products are currently only being manufactured for research use at clinical labs, universities and pharmacies. However, with the recent grant award, Qin says the company's research team plans to spend the next three to five years preparing the products for worldwide commercialization.


Dr. Lidong Qin is a professor at the Houston Methodist Research Institute's department of nanomedicine. He launched iBiochips as an independent faculty startup that licensed technology from Houston Methodist.Courtesy of Lidong Qin

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Here's what interactive, virtual events to log on to this month. Getty Images

Despite much of the state returning to some state of normalcy, larger groups are still not encouraged to gather quite yet in order to avoid an uptick in COVID-19 cases.

With that in mind, here are over 10 Houston innovation events you can attend virtually via online meetings. Be sure to register in advance, as most will send an access link ahead of the events.

June 2 — How Fashion Brands Optimize E-Commerce and Sustainability During a Pandemic

Kim Roxie, founder of LAMIK Beauty, moderates a panel of e-commerce startup founders for The Ion to discuss modern issues the female founders are facing.

Details: The event is at 5:30 p.m. on Tuesday, June 2. Learn more.

June 4 — Startup Growth After COVID-19 with Sputnik ATX

Curious about what business and startup growth may look like post-COVID-19? Join Sputnik ATX Partner Joe Merrill via General Assembly for a discussion on how to grow a business and raise a round during a pandemic.

Details: The event is at 3 p.m. on Thursday, June 4. Learn more.

June 6 — Enventure Basecamp: Business Building Workshop

Our community-driven business building basecamp series returns this June to support a local innovator construct their healthcare venture.

Details: The event is at 9 a.m. on Saturday, June 6. Learn more.

June 9 — Pulse Check-Today's Funding Landscape

Today's current crisis has changed the mindset of many industry strategic partners, investors and overall stakeholders. From pivoting investment priorities, to identifying new areas of innovation, the investor landscape is constantly shifting.

For small to medium sized biotechs, it can be hard to keep up with promised milestones while also planning and anticipating the future of their companies. How could companies be preparing for not only the short-term but for years to come? What should be prioritized in the coming months? Who is still investing? How can they find the right partners for them as they move forward?

Details: The event is at 11 a.m. on Tuesday, June 9. Learn more.

June 9 — VC Ask Me Anything Virtual Event featuring The Artemis Fund

These livestreams, which will include audience Q&A, will tackle the big questions on everyone's mind, like how founders should adjust in the face of the pandemic and what fundraising will look like once the pandemic loosens its grip. Click here to stream.

Details: The event is at 2 to 3 p.m. on Tuesday, June 9. Learn more.

June 11 — Energy and Utilities: Drones, Connectivity, and Operations of the Future

Preparing for the future can be confusing. How can you keep up with industry and regulatory advancements, or know when to invest in new technology? That's why we teamed up with Southern Company to share how they're preparing — and how you can, too. Join Skyward and Southern Company for a discussion about energy and utility operations of the future and practical steps you can take now to prepare your enterprise.

Details: The event is at 1 p.m. on Thursday, June 11. Learn more.

June 11 — Venture vs The Virus: Texas Halo Fund IV

The Houston Angel Network presents Episode 3 of Venture vs The Virus. During this virtual event you will hear from the managing directors of the Texas Halo Fund on the launch of their new fund and the investment opportunities they are seeing as a result of the health crisis.

Details: The event is at 2 p.m. on Thursday, June 11. Learn more.

June 11 — Intro to Fundraising in FemTech & AMA with Juliana Garaizar and Dr. Barreto

Are you raising capital for your FemTech startup? Join us VIRTUALLY for an overview from venture capitalists and investors at Intro to Fundraising in FemTech & Ask Me Anything!

Details: The event is at 2 p.m. on Thursday, June 11. Learn more.

June 16 — Women in Tech Summit presented by Accenture

Capital Factory will host a virtual Women In Tech Summit dedicated to increasing diversity in the entrepreneurial and tech community while making its coworking space an inclusive environment for all.

Attendees can look forward to a special keynote guest, insightful fireside chats, discussion sessions, a startup showcase, Epic Office Hours, and panels on relevant topics facing the tech ecosystem.

Details: The event is at noon to 5 p.m. on Tuesday, June 16. Learn more.

June 17-19 — Virtual Rice Business Plan Competition

This year's Rice Business Plan Competition, which was planned for March 26 to 28, was canceled due to COVID-19, but the Rice Alliance for Technology and Entrepreneurship has decided to offer up an alternative: A virtual RBPC. Forty two student teams will compete over three virtual events.

Details: The event is from June 17 to 19. Learn more.

June 23 — Virtual Fireside Chat: Fredrik Tukk, Maersk Drilling

Join The Ion for a chat with Fredrik Tukk-Head of Innovation Scouting at Maersk Drilling about how organizations can benefit from innovation

Details: The event is at 3 p.m. on Tuesday, June 23. Learn more.

June 24 — The Ion Startup Demo Day

Top tier mentors, local investors, and personalized pitch feedback for participating startups -- nothing's changed but the address. Whether you're a serial entrepreneur or just looking to get involved in the community, this event is for YOU.

Details: The event is at 6 p.m. on Wednesday, June 24. Learn more.

June 30 — TMC Accelerator for Cancer Therapeutics Info Session

The TMC ACT team will answer questions including who should apply to TMC ACT, what are the timelines, and what value to expect.

Details: The event is at 3 p.m. on Tuesday, June 30. Learn more.

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