collaborate for a cure

UT system funds Houston researchers in new collaboration to cure cancer

Five cancer research teams have been selected to receive funds from a new initiative from the University of Texas. Photo via news.utexas.edu

In a renewed effort to move the needle on finding a cure for cancer, the University of Texas system has launched a new collaboration in oncological data and computational science across three programs.

Houston-based University of Texas MD Anderson Cancer Center has teamed up with two UT Austin schools — the Oden Institute for Computational Engineering and Sciences and the Texas Advanced Computing Center. The collaboration was announced this summer to tap into mathematical modeling and advanced computing along with oncology expertise to inspire new methods of cancer treatment.

"Integrating and learning from the massive amount of largely unstructured data in cancer care and research is a formidable challenge," says David Jaffray, Ph.D., chief technology and digital officer at MD Anderson, in a news release. "We need to bring together teams that can place quantitative data in context and inform state-of-the-art computational models of the disease and accelerate progress in our mission to end cancer."

Now, the first five projects to be funded under this new initiative have been announced.

  • Angela Jarrett of the Oden Institute and Maia Rauch of MD Anderson will develop a patient-specific mathematical model for forecasting treatment response and designing optimal therapy strategies for patients with triple-negative breast cancer.
  • Caroline Chung of MD Anderson and David Hormuth of the Oden Institute are using computational models of the underlying biology to fundamentally change how radiotherapy and chemotherapy are personalized to improve survival rates for brain cancer patients.
  • Ken-Pin Hwang of MD Anderson and Jon Tamir of UT Austin's Department of Electrical and Computer Engineering and the Oden Institute will use mathematical modeling and massively parallel distributed computing to make prostate MR imaging faster and more accurate to reduce the incidence of unnecessary or inaccurate biopsies.
  • Xiaodong Zhang of MD Anderson and Hang Liu of TACC will advance both the planning and delivery of proton therapy via a platform that combines mathematical algorithms and high-performance computing to further personalize these already highly tailored treatments.
  • Tinsley Oden and Prashant Jha of the Oden Institute and David Fuentes of MD Anderson will integrate a new mechanistic model of tumor growth with an advanced form of MRI to reveal underlying metabolic alterations in tumors and lead to new treatments for patients.

"These five research teams, made up of a cross section of expertise from all three stakeholders, represent the beginning of something truly special," says Jaffray in a release. "Our experts are advancing cancer research and care, and we are committed to working with our colleagues at the Oden Institute and TACC to bring together their computational expertise with our data and insights."

Later this month, the five teams will log on to a virtual retreat along with academic and government thought leaders to further collaborate and intertwine their research and expertise.

"Texas is globally recognized for its excellence in computing and in cancer research. This collaboration forges a new path to international leadership through the combination of its strengths in both," says Karen Willcox, director of the Oden Institute. "We are thrilled that leaders in government, industry and academia see the potential of this unique Texan partnership. We're looking forward to a virtual retreat on October 29 to continue to build upon this realization."

Trending News

Building Houston

 
 

Ty Audronis founded Tempest Droneworx to put drone data to work. Photo courtesy of Tempest Droneworx

Ty Audronis quite literally grew up in Paradise. But the Northern California town was destroyed by wildfire in 2018, including Audronis’ childhood home.

“That’s why it’s called the Campfire Region,” says the founder, who explains that the flames were started by a spark off a 97-year-old transmission line.

But Audronis, who has literally written the book on designing purpose-built drones — actually, more than one — wasn’t going to sit back and let it happen again. Currently, wildfire prevention is limited to the “medieval technology” of using towers miles apart to check for smoke signals.

“By the time you see smoke signals, you’ve already got a big problem,” Audronis says.

His idea? To replace that system with real-time, three-dimensional, multi-spectral mapping, which exactly where his company, Tempest Droneworx, comes in.

When asked how he connected with co-founder Dana Abramowitz, Audronis admits that it was Match.com — the pair not only share duties at Tempest, they are engaged to be married. It was a 2021 pre-SXSW brainstorming session at their home that inspired the pair to start Tempest.

When Audronis mentioned his vision of drone battalions, where each is doing a specialized task, Abramowitz, a serial entrepreneur and founder who prefers to leave the spotlight to her partner, told him that he shouldn’t give the idea away at a conference, they should start a company. After all, Audronis is a pioneer in the drone industry.

“Since 1997, I’ve been building multicopters,” he says.

Besides publishing industry-standard tomes, he took his expertise to the film business. But despite its name, Tempest is a software company and does not make drones.

That software is called Harbinger. Audronis explains that the real-time management and visualization solution is viewable on practically any device, including mobile or augmented reality. The system uses a video game engine for viewing, but as Audronis puts it, “the magic happens” on the back end.

Harbinger is not just drone-agnostic, but can use crowd-sourced data as well as static sensors. With the example of wildfires in mind, battalions can swarm an affected area to inform officials, stopping a fire before it gets out of hand. But fires are far from Harbinger’s only intended use.

The civilian version of Harbinger will be available for sale at the end of 2023 or beginning of 2024. For military use, Navy vet Audronis says that the product just entered Technical Readiness Level (TRL) 5, which means that they are about 18 months away from a full demo. The latest news for Tempest is that earlier this month, it was awarded a “Direct to Phase II” SBIR (Government Small Business Innovation Research) contract with the United States Department of the Air Force.

Not bad for a company that was, until recently, fully bootstrapped. He credits his time with the Houston Founder Institute, from which he graduated last February, and for which he now mentors, with many of the connections he’s made, including SBIR Advisors, who helped handle the complex process of getting their SBIR contract.

And he and Abramowitz have no plans to end their collaborations now that they’re seeing growth.

“Our philosophy behind [our business] isn’t keeping our cards close to our vest,” says Audronis. “Any potential competitors, we want to become partners.”

The company was just the two founders until five weeks ago, when Tempest’s size doubled, including a full-time developer. Once Tempest receives its SIBR check, the team will grow again to include more developers. They are currently looking for offices in the city. As Audronis says, Tempest Droneworx is “100-percent made in Houston.” Paradise may have been lost, but with Harbinger soon to be available, such a disaster need never happen again.

Dana Abramowitz and Ty Audronis co-founded Tempest Droneworks. Photo courtesy of Tempest Droneworx

Trending News