UT system funds Houston researchers in new collaboration to cure cancer

collaborate for a cure

Five cancer research teams have been selected to receive funds from a new initiative from the University of Texas. Photo via news.utexas.edu

In a renewed effort to move the needle on finding a cure for cancer, the University of Texas system has launched a new collaboration in oncological data and computational science across three programs.

Houston-based University of Texas MD Anderson Cancer Center has teamed up with two UT Austin schools — the Oden Institute for Computational Engineering and Sciences and the Texas Advanced Computing Center. The collaboration was announced this summer to tap into mathematical modeling and advanced computing along with oncology expertise to inspire new methods of cancer treatment.

"Integrating and learning from the massive amount of largely unstructured data in cancer care and research is a formidable challenge," says David Jaffray, Ph.D., chief technology and digital officer at MD Anderson, in a news release. "We need to bring together teams that can place quantitative data in context and inform state-of-the-art computational models of the disease and accelerate progress in our mission to end cancer."

Now, the first five projects to be funded under this new initiative have been announced.

Angela Jarrett of the Oden Institute and Maia Rauch of MD Anderson will develop a patient-specific mathematical model for forecasting treatment response and designing optimal therapy strategies for patients with triple-negative breast cancer.
Caroline Chung of MD Anderson and David Hormuth of the Oden Institute are using computational models of the underlying biology to fundamentally change how radiotherapy and chemotherapy are personalized to improve survival rates for brain cancer patients.
Ken-Pin Hwang of MD Anderson and Jon Tamir of UT Austin's Department of Electrical and Computer Engineering and the Oden Institute will use mathematical modeling and massively parallel distributed computing to make prostate MR imaging faster and more accurate to reduce the incidence of unnecessary or inaccurate biopsies.
Xiaodong Zhang of MD Anderson and Hang Liu of TACC will advance both the planning and delivery of proton therapy via a platform that combines mathematical algorithms and high-performance computing to further personalize these already highly tailored treatments.
Tinsley Oden and Prashant Jha of the Oden Institute and David Fuentes of MD Anderson will integrate a new mechanistic model of tumor growth with an advanced form of MRI to reveal underlying metabolic alterations in tumors and lead to new treatments for patients.

"These five research teams, made up of a cross section of expertise from all three stakeholders, represent the beginning of something truly special," says Jaffray in a release. "Our experts are advancing cancer research and care, and we are committed to working with our colleagues at the Oden Institute and TACC to bring together their computational expertise with our data and insights."

Later this month, the five teams will log on to a virtual retreat along with academic and government thought leaders to further collaborate and intertwine their research and expertise.

"Texas is globally recognized for its excellence in computing and in cancer research. This collaboration forges a new path to international leadership through the combination of its strengths in both," says Karen Willcox, director of the Oden Institute. "We are thrilled that leaders in government, industry and academia see the potential of this unique Texan partnership. We're looking forward to a virtual retreat on October 29 to continue to build upon this realization."

Houston Methodist stood out yet again on an annual best hospitals report, but several other Houston institutions were recognized as well. Courtesy of Methodist Hospital/Facebook

New report recognizes best hospitals in Houston

better than all the rest

Hospitals across Houston were ranked by their patient care, patient safety, outcomes, nursing, advanced technology and reputation in an annual report that identifies the top medical facilities in the country.

U.S. News & World Report released its 31st annual best hospital rankings this week, which included both adult and children's hospital tracks across several categories. The report released both overall and local rankings after evaluating over 4,500 medical centers nationwide in 16 specialties, and 134 hospitals were ranked in at least one specialty.

For the ninth year in a row, the top hospital in Houston and Texas, according to the report, is Houston Methodist, which ranked at No. 20 nationally and made the report's Honor Roll.

"Our U.S. News rankings are especially meaningful right now as this has been an exceptionally difficult time for our health care workers," says Marc Boom, M.D., president and CEO of Houston Methodist, in a news release. "We have always served our community by providing exceptional care — during the COVID-19 pandemic and before. It's a true testament to our commitment to being unparalleled."

Houston Methodist Sugar Land Hospital tied for No. 4 in Houston and No. 6 (three-way tie) in Texas. Additionally, the hospital was recognized on the top lists for 11 specialties:

No. 12 for cardiology/heart surgery
No. 13 for orthopedics
No. 14 for gastroenterology/GI surgery
No. 17 for cancer
No. 19 (tie) for nephrology
No. 20 for pulmonology and lung surgery
No. 23 for neurology/neurosurgery
No. 26 for geriatrics
No. 26 (tie) for gynecology
No. 28 for diabetes and endocrinology
No. 49 for ear, nose and throat

The second-best hospital in Houston on this year's ranking was Baylor St. Luke's Medical Center, which was also named the No. 3 hospital in the state.

"At Baylor St. Luke's, we are transforming the way we deliver care for our patients through groundbreaking technologies and a multidisciplinary approach that allows us to give the best possible care to patients and their families," says Doug Lawson, CEO of St. Luke's Health, in a news release. "I praise our dedicated staff and physicians for helping us achieve this recognition."

Baylor St. Luke's also made an appearance across five specialties:

No. 17 for cardiology/heart surgery
No. 21 for gastroenterology/GI surgery
No. 21 for neurology/neurosurgery
No. 27 for cancer
No. 47 for geriatrics

"This is a great report that confirms the efforts of our partnership at Baylor St. Luke's and our affiliated hospitals to provide unsurpassed care to patients, conduct research that will change lives and train the next generation of physicians", says Dr. Paul Klotman, president, CEO, and executive dean at Baylor College of Medicine. "Baylor St. Luke's high ranking in Texas is in parallel with Baylor College of Medicine being the highest ranked medical school in Texas. Together, we are an outstanding academic medical center and learning health system."

Memorial Hermann - Texas Medical Center came in No. 3 in Houston and No. 5 in Texas. The hospital ranked in one adult specialty and two children's specialties.

No. 43 for ear, nose and throat (adult)
No. 22 for cardiology/heart surgery (pediatric)
No. 31 for neurology/neurosurgery (pediatric)

On the children's hospital track, Houston's Texas Children's Hospital ranked as No. 4 nationally and was recognized in all 10 pediatric specialties, which included:

No. 1 for pediatric cardiology/heart surgery
No. 2 for pediatric nephrology
No. 2 for pediatric neurology/neurosurgery
No. 3 for pediatric pulmonology and lung surgery
No. 4 for pediatric cancer
No. 5 for pediatric diabetes and endocrinology
No. 5 for pediatric gastroenterology/GI surgery
No. 6 for pediatric urology
No. 10 for neonatology
No. 15 for pediatric orthopedics

Zooming in on the specific specialties, several other Houston hospitals in addition to these top tier hospitals, secured spots in the top 10 rankings.

University of Texas MD Anderson Cancer Center was ranked No. 1 nationally for adult cancer treatment. Additionally, the hospital made an appearance in six other adult specialties and one pediatric specialty.

No. 4 for ear, nose and throat
No. 6 for urology
No. 14 for gynecology
No. 27 for diabetes and endocrinology
No. 41 for geriatrics
No. 46 for gastroenterology/GI surgery
No. 38 for cancer (pediatric)

TIRR Memorial Hermann in Houston ranked No. 3 nationally for rehabilitation.

For all 31 years, The Menninger Clinic has been recognized as a top hospital in the psychiatric speciality. This year, the clinic ranked at No. 9 nationally.

"Our clinical teams provide personalized care with the right blend of art and science. We have pioneered measuring the effectiveness of this treatment, and the results consistently demonstrate that patients sustain their well-being for at least a year after they leave Menninger," says Armando Colombo, president and CEO, in a news release. "Going forward, we will improve access to make it easier for more Texans to access these life-changing results."

Othram and the University of Texas M.D. Anderson Cancer Center have teamed up to create a modern forensic sequencing lab program. Getty Images

New program in Houston is training future forensic scientists and digitizing DNA evidence

crime scene innovation

Houston-area's first-privately held forensic sequencing laboratory has partnered with The University of Texas M.D. Anderson Cancer Center to create an academic program that will provide forensic training to genome scientists that will help them crack previously unsolved criminal cases.

Othram was created in 2018 specifically to apply the power of modern DNA parallel sequences to forensic evidence. Its new academic program partnership is aimed at training Molecular Genetic Technology (MGT) graduate students in the newest laboratory techniques and technology for the recovery and analysis of human DNA from deteriorated or contaminated materials.

"Because this field is so new, there aren't many individuals who are experts in both genomics and forensic science," David Mittelman, CEO and founder of Othram, tells InnovationMap. "We wanted to collaborate with M.D. Anderson who has a great genetic testing program already to help students learn about how to apply current techniques that are being used to solve cases that no one else can solve."

MGT students, who study the role of genetics in medicine, will be able to train with Othram experts using new technological advances such as the ability to harness whole-genome shotgun sequencing for the unique needs that forensic evidence demands like human identification.

"The Texas Medical Center is the best in the world, specifically for genomics training so it seemed like a natural fit," says Mittelman. "Especially since we want to attract and expose students to this new area of forensics as a possible outlet."

The use of new technology is what sets Othram apart, last year they helped solved a 103-year old mystery of a headless torso found in an Idaho cave, using their Forensic-Grade Genome SequencingTM technology. The DNA extraction and sequencing lab at Othram distill the sample DNA down to a sequence, which with the help of computer software, can be analyzed to reconstruct the whole genome of an individual's DNA.

Then the DNA is digitized and matched to other databases such as the FBI's Combined DNA Index System to cross-reference for a DNA match. With Othram's ability to construct whole genomes from previously unusable DNA samples, they can further the search to identify human remains or identify suspects from living relatives.

"There is no one currently leveraging whole genome sequencing right now like Othram," says Mittelman. "There's a whole range of opportunities from taking a look at the whole genome from ancestry to relationship testing and physical trait prediction."

The unique learning experience for MGT students will integrate classroom lectures, laboratory demonstrations, and technological experiences. Mittleman says that the academic program partnership will enable a new generation of forensic genomics scientists to digitize the nation's DNA evidence and solve cold cases.

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Houston-based creator economy platform goes live nationally

so clutch

An app that originally launched on Houston college campuses has announced it's now live nationwide.

Clutch founders Madison Long and Simone May set out to make it easier for the younger generation to earn money with their skill sets. After launching a beta at local universities last fall, Clutch's digital marketplace is now live for others to join in.

The platform connects brands to its network of creators for reliable and authentic work — everything from social media management, video creation, video editing, content creation, graphic design projects, and more. With weekly payments to creators and an inclusive platform for users on both sides of the equation, Clutch aims to make digital collaboration easier and more reliable for everyone.

“We’re thrilled to bring our product to market to make sustainable, authentic lifestyles available to everyone through the creator economy," says May, CTO and co-founder of Clutch. "We’re honored to be part of the thriving innovation community here in Houston and get to bring more on-your-own-terms work opportunities to all creators and businesses through our platform.”

In its beta, Clutch facilitated collaborations for over 200 student creators and 50 brands — such as DIGITS and nama. The company is founded with a mission of "democratizing access to information and technology and elevating the next generation for all people," according to a news release from Clutch. In the beta, 75 percent of the creators were people of color and around half of the businesses were owned by women and people of color.

“As a Clutch Creator, I set my own pricing, schedule and services when collaborating on projects for brands,” says Cathy Syfert, a creator through Clutch. “Clutch Creators embrace the benefits of being a brand ambassador as we create content about the products we love, but do it on behalf of the brands to help the brands grow authentically."

The newly launched product has the following features:

Creator profile, where users can share their services, pricing, and skills and review inquiries from brands.
Curated matching from the Clutch admin team.
Collab initiation, where users can accept or reject incoming collab requests with brands.
Collab management — communication, timing, review cycles — all within the platform.
In-app payments with a weekly amount selected by the creators themselves.
Seamless cancellation for both brands and creators.

Clutch raised $1.2 million in seed funding from Precursor Ventures, Capital Factory, HearstLab, and more. Clutch was originally founded as Campus Concierge in 2021 and has gone through the DivInc Houston program at the Ion.

Madison Long, left, and Simone May co-founded Clutch. Photo courtesy of Clutch

2 Houston suburbs roll onto top-15 spots on U-Haul’s list of growing cities

on the move

More movers hauled their belongings to Texas than any other state last year. And those headed to the Greater Houston area were mostly pointed toward Missouri City and Conroe, according to a new study.

In its recently released annual growth report, U-Haul ranks Missouri City and Conroe at No. 13 and No. 19, respectively among U.S. cities with the most inbound moves via U-Haul trucks in 2022. Richardson was the only other Texas cities to make the list coming in at No. 15.

Texas ranks No. 1 overall as the state with the most in-bound moves using U-Haul trucks. This is the second year in a row and the fifth year since 2016 that Texas has earned the distinction.

“The 2022 trends in migration followed very similar patterns to 2021 with Texas, Florida, the Carolinas and the Southwest continuing to see solid growth,” U-Haul international president John Taylor says in a news release. “We still have areas with strong demand for one-way rentals. While overall migration in 2021 was record-breaking, we continue to experience significant customer demand to move out of some geographic areas to destinations at the top of our growth list.”

U-Haul determines the top 25 cities by analyzing more than 2 million one-way U-Haul transactions over the calendar year. Then the company calculated the net gain of one-way U-Haul trucks entering a specific area versus departing from that area. The top U-Haul growth states are determined the same way.

The studies note that U-Haul migration trends do not directly correlate to population or economic growth — but they are an “effective gauge” of how well cities and states are attracting and maintaining residents.

Missouri City is known for its convenient location only minutes from downtown Houston. The city’s proximity to major freeways, rail lines, the Port of Houston, and Bush and Hobby Airports links its businesses with customers “around the nation and the world,” per its website.

The No. 19-ranked city of Conroe is “the perfect blend of starry nights and city lights,” according to the Visit Conroe website. Conroe offers plenty of outdoor activities, as it is bordered by Lake Conroe, Sam Houston National Forest and W. Goodrich Jones State Forest. But it also has a busy downtown area with breweries, theaters, shopping and live music.

To view U-Haul’s full growth cities report, click here.

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This article originally ran on CultureMap.

Houston expert: Space tourism is the future — do we have the workforce to run it?

guest column

Throughout history, humans have always been fascinated in exploring and traveling around the world, taking them to many exotic places far and away. On the same token, ever since the dimension of space travel has been inaugurated with multiple private companies launching rockets into space, it has become an agenda to make space travel public and accessible to all. We believe that space travel is the next frontier for tourism just like for our forefathers world travel to faraway places was the next frontier, for recreational and adventure purposes.

In a world racing on technology, we can picture flying cars, invisible doors, and international cuisine in space. With this rapid expansion of the land, the idea of space tourism has stirred the space industry to think about running businesses, start trade, and set up universalization beyond the ring of the earth. It is no longer science fiction but our immediate future. However, the true question remains. Who will be responsible for all of it? Are we training the right workforce that is needed to build and run all of this?

Space tourism is an exciting idea in theory, traveling to extra-terrestrial destinations, exploring new planets, all by being in an anti-gravitational environment. Through these diminishing borders and rapid advancements soon we'll be living the space life, all the virtual, metaverse gigs coming to reality. But before that let's explore space tourism and how the solar system will welcome humans.

What is Space tourism?

Ever since 1967, Apollo opened the getaway of space travel and the technological intervention spun to rise. Just like nomad tourism, space tourism is human space travel for commercializing interstellar for leisure or pleasurable adventures of the unknown. Space has different levels of horizons, according to research, orbital space has high speeds of 17,400 mph to allow the rocket to orbit around the Earth without falling onto the land. While lunar space tourism goes into subcortical flights and brings people back at a slower speed.

Studies have shown that in the upcoming years, commercial space exploration will hike up the economical database, by generating more than expected revenue. On these grounds, space tourism won't be limited to suborbital flights but rather take onto orbital flights, this revolutionary expenditure will change the future.

Everything aligns when the right team works together endlessly to reach the stars. The space exploration will only take place with enthusiastic and empowered individuals catering towards their roles.

Astronomers, space scientists, meteorologists, plasma physicists, aerospace engineers, avionics technicians, technical writers, space producers, and more will work in the field to make this space dream come true.

The attraction of Space exploration

Curiosity is the gateway to the seven wonders of the world. Humans are born with novelty-seeking, the drive to explore the unknown and push boundaries. This exploration has benefited society in a million ways, from making bulbs to jets.

The attraction towards exploring the space stems from the same desire for novelty seeking. We want to answer the most difficult questions about the universe, is there only darkness beyond that sky? Can we live on another planet if ours die? To address the challenges of space and the world, we have created new technologies, industries, and a union worldwide. This shows how vital space exploration is to humans. Many astronauts dwell on the idea of seeing the iconic thin blue outline of our planet, the quintessential experience makes the astronaut go back and back. However, are we entering this dimension with the right skills? Is our future workforce ready to take need the best

Who will lead the path?

The main question that still goes unanswered is who will run space tourism. When it comes to the future, there are infinite options. One decision and you will fly into an endless sky.

This expenditure has opened multiple career opportunities for the future workforce to take on for diversification and exploration of space. Currently, we cannot predict how people will find meaning and improve their lives through space tourism, but it will be a soul-awakening experience. According to experts, travelers would prefer a livelihood in space for which companies are working day and night to figure out accommodation and properties. The ideas include having space hotels, offices, research labs, and tents for operations.

Lastly, space tourism is just a start, we are moving into a dimensional field of physics and astronomy to create new opportunities and ground-breaking inventions to explore the untouchable. The new era of more refined and thoroughly accessed careers are on the rise, let's see how the world evolves in the next 10 years.