funds granted

University of Houston researcher receives grant for first-of-its-kind breast cancer drug

A UH researcher has fresh funding to support her life-saving, cancer-fighting drug. Photo via UH.edu

A University of Houston researcher was awarded a $2 million grant from the Cancer Prevention and Research Institute of Texas to develop a new drug that will initially target breast cancer, the university announced this month.

The drug is intended to impact a type of traditionally "undraggable" target of cancer, known as intrinsically disordered proteins (IDPs), which researchers have yet to gain fundamental understanding of. According to the release, approximately 70 percent of proteins impacted by cancer are considered IDPs.

Gül Zerze, an assistant professor in the William A. Brookshire Department of Chemical and Biomolecular Engineering at the UH Cullen College of Engineering, has specialized in research on the computational modeling and simulations of these IDPs, and is one of the 12 cancer researchers awarded such a grant by the CPRIT.

Candidates for Zerze's drug will be rapidly tested through collaborations within UH and MD Anderson, according to the statement.

Gül Zerze is an assistant professor in the William A. Brookshire Department of Chemical and Biomolecular Engineering. Photo via UH.edu

"One out of nearly six Texas women diagnosed with breast cancer will die of the disease. Importantly, Texan women of color are disproportionately impacted by the high mortality rate compared to white Texan women (41 percent higher mortality rate reported for Black Texan women in 2016)," Zerze said in a statement. "This high mortality rate, despite the substantial efforts made for early diagnosis, calls for better therapeutics urgently.”

Zerze was recruited by the CPRIT to come to UH from Princeton last November. She was part of the latest class of recruitment grants from the organization, totaling $38 million to “form a critical ecosystem of distinguished cancer-fighting talent” in Texas.

According to the CPRIT website, the organization has recruited 263 cancer researchers and their labs to Texas over the years. First launched in 2007, the CPRIT is now a $6 billion, 20-year initiative that's allowing institutions in Houston compete against the likes of Harvard and Stanford universities, and the Cleveland and Mayo clinics.

“The ideas proposed here will save lives," Zerze said in the statement. "And the products that will come out of this project have a great potential for commercialization and founding companies to contribute to the Texas economy.”

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Guess what, Houston innovators. Tickets to this year's Houston Innovation Awards are on sale now. Graphic via InnovationMap

You can now buy tickets to the 2023 Houston Innovation Awards on November 8 — but the deadline to nominate deserving individuals and companies for the prestigious awards is just a few days away.

Tickets are available online for the awards event taking place at Silver Street Studios, and InnovationMap has a few options to choose from. Individual tickets are on sale for $80, with a special founder price of $40 available. This year, individual tickets will have seating at a first come, first served basis, but attendees are also able to opt into a reserved table of 10 for $1,000. Sponsors, judges, and finalists and their guests will receive complimentary tickets.

The nomination period for the annual awards is coming to a close next week on Tuesday, September 19. Click here to read about this year's awards categories.The process includes submitting nominations on behalf of yourself or others, and next week, nominees will be sent an application that will be due October 4. A panel of judges will review the applications and finalists will be announced and notified ahead of the event.

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