X marks the spot

5 things to know about TMCx's newest cohort

TMCx's eighth cohort started Monday. Of the 21 companies, 10 are international and two are from Texas. Courtesy of TMCx

On Monday, 21 startups settled in for a wild, four-month ride at the Texas Medical Center's Innovation Institute, and TMCx's eighth cohort, which is focused on digital health, is officially ongoing.

The companies will be absorbing the curriculum and guidance from TMCx and its partners for the next four months, and this particular cohort is exciting for Lance Black, associate director at TMCx, for a few reasons.

"I'm really honored to be able to support these startup companies because, in my mind, it's this entrepreneur spirit that's going to change health care for the better," says Black.

From where the startups are from to where they're going, here's what you need to know about TMCx's eighth cohort.

Digital health companies are defined as those with a software component. 

Each year, TMCx hosts two four-month cohorts — one focusing on medical device companies and the other on digital health. Last fall, TMCx concluded its medical device cohort, so its time to turn the focus on digital health, which Black says TMCx defines as companies with a software element to their product.

The 21 companies in X8 focus on a myriad of medical issues — neurology, mental health, and oncology — as well as logistical applications — patient experience, hospital efficiency, process improvement, clinical decision support, and more.

Black says one type of cohort isn't harder than the other, but the process and curriculum is different. Medical device companies need to have an established prototype, which can take a while. Meanwhile, a digital health company can turn around an app in a matter of weeks.

It might be a bit of a gray area as to what all falls under digital health, but one thing's for sure — TMC is a great opportunity for the companies.

"Overall, our digital health companies do really well in the Texas Medical Center because there's a lot of large hospital systems that are eager and hungry to improve their processes in a number of ways," Black says. "So, we've seen digital health get picked up quickly."

It's the accelerator's most international cohort.

Black says his team evaluated hundreds of startups and, of the 150 companies, 70 were interviewed before getting pared down to 21. What was particularly surprising was the amount of international companies were interested. Ten of the cohort's startups are internationally based.

"What we really tried to do is put the blindfolds on for where they are from and what their background is and really look at the company and its technology, and pick the highest quality of the companies," Black says.

The countries represented are Canada, Australia, Israel, Denmark, and the United Kingdom.

"It shows not only what TMC has done but how Houston has come up in ranking as an international location for these companies," says Black. "For the majority of the 10, this is their first time in the U.S. They are looking at Houston as their entry to the U.S. market."

One Houston company made the cut.

Texas has two companies in the cohort — one from Austin and one from Houston.

Houston-based PreopMD makes the preoperative experience — for patients and clinicians — a whole lot easier. Improved patient communications and monitoring is the main goals of the company, and the website describes the technology as a "virtual operating room command center."

Austin-based Cloud 9 is on a mission to make mental health care more accessible to the population. According to their website, 20 percent of the population has mental health issues, but only 8 percent receive treatment. By engaging mental health care providers and making access to data and communication more available, Cloud 9 can help to fix the broken system.

There's a new guy in charge. 

After TMCx's former director, Erik Halvorsen, left his position in December, Black has stepped up to the plate as interim director to lead the cohort. The responsibilities are definitely different, Black says.

"As a strategist my focus was primarily the companies and being their point of contact," he says. "My day to day had a lot to do with communicating with the companies, and making sure they got the most out of the program. Now, in my current role, It's a little bit one step removed from that. I'm looking over the entire program and thinking about it strategically."

Black says that for him this means finding areas where the cohort can be improved or expanded.

It's the best time to be a TMCx company.

In the past few years, Black says the program has improved dramatically from the curriculum to the programing and what TMC has to offer its startups.

Now, the cohort has access to local talent through the intern program, fundraising events, the new Center of Device Innovation, and more.

"The more that we throw at them, the more they absorb and the better that they do," Black says. "So, we're always looking for ways to improve on their experience."


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Building Houston

 
 

Free mental health care, local COVID-19 testing, and a new great to fund an ongoing study — here's your latest roundup of research news. Image via Getty Images

As Houston heads toward the end of summer with no major vaccine or treatment confirmed for COVID-19, local research institutions are still hard at work on various coronavirus-focused innovations.

Free mental health care, local COVID-19 testing, and a new great to fund an ongoing study — here's your latest roundup of research news.

Baylor College of Medicine genomics team to partner for local COVID-19 testing

Houston millionaire to start biotech accelerator for companies focusing on regenerative medicine

Two departments at BCM are working with the county on COVID-19 testing. Getty Images

Two Baylor College of Medicine institutions have teamed up to aid in local COVID-19 testing. The Human Genome Sequencing Center and the Alkek Center for Metagenomics and Microbiome Research — under the leadership of BCM — are partnering with local public health departments to provide polymerase chain reaction testing of COVID-19 samples, according to a news release from BCM.

"We are pleased to work with the outstanding local government groups in this critical public health effort," says Dr. Richard Gibbs, director of the HGSC and Wofford Cain chair and professor of molecular and human genetics at Baylor, in the release. "We are proud of the tireless determination and expertise of our centers and college staff that enabled the rapid development of this robust testing capacity to serve the greater Houston community."

Baylor is among the testing providers for Harris County Public Health, and people can receive testing following a pre-screening questionnaire online.

"We are fortunate to have Baylor College of Medicine as a close partner during the COVID-19 pandemic," says Dr. Umair Shah, executive director of Harris County Public Health, in the release. "This is a challenging time for our community and as the need for increased testing capacity and getting results to residents faster has grown, Baylor has risen to the occasion. There are countless unsung heroes across Harris County who have stepped up to the plate during this pandemic and Baylor College of Medicine is one of them."

COVID-19 testing samples are collected from testing sites and delivered to the Alkek Center. After isolating the virus, genomic material is extracted and sent to the HGSC to quantitative reverse transcription PCR testing. Should the sample's RNA sequence match the virus, then it is positive for COVID-19. The sequencing must test positive three times to be considered overall positive.

Results are returned within 48 hours, and the lab has a capacity of more than 1,000 samples a day. Since May, the team has tested over 30,000 samples.

"We knew we had all the pieces to stand up a testing center fast – large scale clinical sequencing, experts in virology and molecular biology, and a secure way to return results to patients," says Ginger Metcalf, Human Genome Sequencing Center Director of Project Development, in the release. "We are also fortunate to have such great partners at Harris County Public Health, who have done an amazing job of gathering, tracking and delivering samples, especially for the most at-risk members of our community."

National Science Foundation renews Rice University funding amid pandemic

José Onuchic (left) and Peter Wolynes are co-directors of the Center for Theoretical Biological Physics at Rice University. Photo by Jeff Fitlow/Rice University

Rice University's Center for Theoretical Biological Physics has been granted a five-year extension from the National Science Foundation. The grant for $12.9 million will aid in continuing the CTBP's work at the intersection of biology and physics.

The center — which was founded in 2001 at the University of California, San Diego, before moving to Rice in 2011 — is led by Peter Wolynes and José Onuchic.

"We have four major areas at the center," Onuchic says in a news release. "The first is in chromatin theory and modeling, developing the underlying mathematical theory to explain the nucleus of the cell — what Peter calls the 'new nuclear physics.' The second is to test ideas based on the data being created by experimentalists. The third is to understand information processing by gene networks in general, with some applications related to metabolism in cancer. The fourth is to study the cytoskeleton and molecular motors. And the synergy between all of these areas is very important."

Onuchic adds that an upcoming donation of a supercomputer by AMD will help the center's ongoing research into COVID-19 and four institutions — Rice, Northeastern, Baylor College of Medicine and the University of Houston — are working collaboratively on the study,

"We're all set to move on doing major COVID-related molecular simulations on day one," he says in the release. "The full functioning of a center requires a synergy of participation. Rice is the main player with people from multiple departments, but Baylor, Northeastern and Houston play critical roles."

University of Houston offers free mental health therapy for restaurant workers

Texas restaurant workers can get free mental health care from a UH initiative. Photo via Elle Hughes/Pexels

Through a collaboration with Southern Smoke and Mental Health America of Greater Houston, the University of Houston Clinical Psychology program launched a a free mental health care program for Texas-based food and beverage employees and their children.

"During normal times this is a high stress industry where people work very hard in environments where they are just blowing and going all the time," says John P. Vincent, professor of psychology and director of the UH Center for Forensic Psychology, in a news release.

The program has 14 graduate students who converse with a total of 30 patients and meet weekly with supervisors at UH.

"This opportunity allows our clinical program to reach people in the community who usually don't have access to mental health services," says Carla Sharp, professor of psychology and director of clinical training, in the release.

For restaurant industry workers looking for help and care, they can visit the Mental Health Services page on Southern Smoke's website.

According to Vincent, this is just the beginning.

"We're discussing it," says Vincent in the release. "But as far as I'm concerned it can just keep going and going."

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