How this community-focused coworking concept plans to continue growth around Houston and beyond

HOUSTON INNOVATORS PODCAST EPISODE 235

Jon Lambert, CEO of The Cannon, joins the Houston Innovators Podcast to discuss the growth of The Cannon, including its newest location. Photo courtesy of The Cannon

For the past five years as CEO, Jon Lambert has faced some challenges leading The Cannon — from navigating a global pandemic to the subsequent evolved real estate market. But now, the coworking and community building company is poised for even more growth — especially with its ninth location opening up this month — thanks to its community-driven mission.

The Cannon Memorial opens its doors on Monday, May 13, with a week of free coworking and events. And while the new space, developed in partnership with MetroNational, is open for leasing, Lambert says on the Houston Innovators Podcast the first and foremost, The Cannon is a community.

"The Cannon wasn't created as a real estate play — we got into coworking because as we started supporting the community and asking the question of, 'what can we do for you?,' one of the highlights was, 'hey, we need space to work,'" he says on the show. "For us, we were going to provide space because that's one of the key needs of this community.

"Our measurement of success is not the buildings we have or the occupancy even — it's what's the success of the companies that are part of the community," he continues.

Lambert shares more about The Cannon's community-focused growth by giving Fulshear as an example. The new community west of Houston isn't currently working on developing a coworking facility yet, but from a programming and digital perspective, The Cannon has established a presence.

"The first phase of the project is to just mobilize the startup and early-stage business community in Fulshear and see what kind of energy and vibe we can create there and connect them to The Cannon's resources and community," Lambert says. "That's our big-picture vision. We can build a new node of community — through a new real estate opportunity, economic development or university relationship — that's beneficial in itself, but that node gets connected to everything else."

With a recent acquisition, The Cannon has further grown its ability to engage its communities digitally. In February, Village Insights, a community management platform, was acquired by The Cannon, onboarding its core employees and further integrating the platform it was already using.

When it comes to its next expansion, The Cannon has a lot of opportunity both around and beyond Houston, Lambert says.

"Any direction is an opportunity and possibility," he says. "I would project that by the end of the year, we'll probably be having another conversation about what The Cannon's doing in other cities as well — for the benefit of The Cannon Community in Houston."

With seven locations across the Houston area, The Cannon's digital technology allows its members a streamlined connection. Photo courtesy of The Cannon

Houston coworking company acquires digital community platform

M&A moves

After collaborating over the years, The Cannon has acquired a Houston startup's digital platform technology to become a "physical-digital hybrid" community.

Village Insights, a Houston startup, worked with The Cannon to create and launch its digital community platform Cannon Connect. Now, The Cannon has officially acquired the business. The terms of the deal were not disclosed.

“The combined commitment to support innovation communities—large and small—is evident,” Andrew Ramirez, who served as CEO for Village Insights ahead of the acquisition, says in a news release. “Village Insights and The Cannon merged to align efforts and cultivate local, regional and global innovation communities. Combining our value propositions represents a significant leap forward for the populations that we serve.”

With seven locations across the Houston area, The Cannon's digital technology allows its members a streamlined connection.

“The Cannon’s hub network stretches from The Woodlands to Galveston and across the 13-county region, with a membership base of more than 900 companies and 3,000 employees,” Jon Lambert, CEO of The Cannon, adds. “The digital extension of our physical footprint brings comprehensive innovation and business development support to communities that need it the most. Cannon Connect’s virtual- connection capabilities stand to remarkably expand our universe of ecosystem opportunities.”

Village Insights was founded in 2020. According to the release, the acquisition began in December, and members of the Village Insights core leadership team have rolled onto new roles at The Cannon.

“The integration of a world-class onsite member experience and Cannon Connect’s superior virtual resource network creates a seamless, streamlined environment for member organizations,” Clemmie Martin, The Cannon’s newly appointed chief of staff, says in the release. “Cannon Connect and this acquisition have paved new pathways to access and success for all.”

Six Italian companies are coming to the Space City to accelerate their businesses thanks to a new program. Photo via nasa.gov

Houston to host 6 Italian aerospace companies with new program

space it up

It's an Italian invasion in Houston — and it's happening in the name of accelerating innovation within aerospace.

For the first time, Italy has announced an international aerospace-focused program in the United States. The Italian Trade Agency and Italian Space Agency will partner with Space Foundation to launch Space It Up, an initiative that will accelerate six companies in Houston.

“The launch of Space It Up marks a pivotal moment in our ongoing commitment to nurturing innovation and facilitating global partnerships," Fabrizio Giustarini, Italian Trade Commissioner of Houston, says in a news release. "This program serves as a testament to the collaborative spirit that defines the aerospace industry. It represents the convergence of Italian ingenuity and Houston's esteemed legacy in space exploration, setting the stage for unprecedented advancements."

The Italian companies in the inaugural cohort represent various areas of cutting-edge aerospace innovations and technologies. The selected companies are:

Arca Dynamics, a space traffic management and Earth observation service provider.
Delta Space, a low-cost satellite connectivity for sensors and launch services.
Involve Space, a pseudo-satellite platform and intelligent software to enable access to space.
Nabu, an IoT and data analysis provider.
NOVAC, which is producing an innovative shapeable all-solid-state structural supercapacitor.
T4i, developing innovative engines to serve small satellite platforms.

ITA and Space Foundation will provide a six-week immersive program focused on the most important aspects of the aerospace industry that will also include business events, networking opportunities, and, ultimately, connect the Houston aerospace community with the Italian startups.

Space It Up will launch its kick-off event at noon on September 1 at Ion Houston, followed by a demo day on September 27. The Demo Day will demonstrate the transformative impact on the aerospace industry by presenting the progress on break-through technologies and projects like the acceleration programs.

The Houston office is one of five ITA offices in the U.S. Other partnerships include Houston-based digital platform leader Village Insights, which will serve as a digital epicenter for Italy’s aerospace companies.

“From the cradle of Renaissance to the frontiers of the cosmos, Italy’s heritage of space innovations knows no bounds,” Keli Kedis Ogborn, Space Foundation vice president of space and entrepreneurship, says in a news release. “With a legacy of scientific advancements, Italy continues to script a new chapter in history, this time with a broader focus on international collaboration and impactful growth to the evolving global space ecosystem.”

This week's roundup of Houston innovators includes James Hury of TRISH, Serafina Lalany of HX, and Andrew Ramirez of Village Insights. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from space health to virtual collaboration — recently making headlines in Houston innovation.

James Hury, deputy director and chief innovation officer of TRISH

James Hury joins the Houston Innovators Podcast to discuss the role of the Translational Research Institute for Space Health. Photo courtesy of TRISH

Only about 500 humans have made it to space, and that number is getting bigger thanks to commercial space travel.

"If you look at all the people who have gone into space, they've mostly been employees of nations — astronauts from different governments," says James Hury of the Translational Research Institute for Space Health on this week's episode of the Houston Innovators Podcast. "We're going to start to get people from all different ages and backgrounds."

Hury is the deputy director and chief innovation officer for Houston-based TRISH, and he's focused on identifying space tech and research ahead of the market that has the potential to impact human health in space. From devices that allow astronauts to perform remote health care on themselves to addressing behavioral health challenges, TRISH is supporting the future of space health. Click here to read more and stream the podcast.

Serafina Lalany, executive director of Houston Exponential

Serafina Lalany, vice president of operations at Houston Exponential

HX has its new permanent leader. Photo courtesy of Serafina Lalany

Houston's nonprofit focused on accelerating the growth of the local innovation ecosystem has named its new leader.

Serafina Lalany has been named Houston Exponential's executive director. She has been serving in the position as interim since July when Harvin Moore stepped down. Prior to that, she served as vice president of operations and chief of staff at HX.

"I'm proud to be leading an organization that is focused on elevating Houston's startup strengths on a global scale while helping to make the world of entrepreneurship more accessible, less opaque, and easier to navigate for founders," Lalany says in a news release. "My team and I will be building upon the great deal of momentum that has already been established in this effort, and I look forward to collaborating closely with members of our community and convening board in this next chapter of HX." Click here to read more.

Andrew Ramirez, CEO of Village Insights

Andrew Ramirez originally worked on a similar project 10 years ago. Photo via LinkedIn

Innovation thrives on collisions, but how do innovators connect without face-to-face connection? Andrew Ramirez and Mike Francis set out to design a virtual village to promote collisions and innovation, and their platform is arriving at an apt time.

"The world has changed," Ramirez says. "I feel like people are trying to find the right balance of the physical but also the productivity gain from being able to do things digitally."

Ramirez leads Village Insights as CEO and the new platform is expected to formally launch it's Open World platform next month. Click here to read more.

This Houston startup is creating a digital platform to create collisions and spark innovation. Image via villageinsights.com

Exclusive: Houston startup is creating a unique digital network to connect innovative communities

virtually innovating

About 10 years ago, Andrew Ramirez was working internally with a corporate team at a Fortune 500 company to build a digital platform that would connect employees to work collaboratively.

"What we really realized is that once you put a lot of people together with a common theme or mission, we started to see a lot of interesting ideas pop up organically," Ramirez tells InnovationMap. "They were creating these collisions without any geographical boundaries."

About a decade later, Ramirez and his former co-worker on the project Mike Francis, revisited the idea of creating this collaborative digital space — with today's technology — for the greater innovation community, and Village Insights was born. Ramirez leads the company as CEO and the new platform is expected to formally launch it's Open World platform next month.

Village Insights allows users to join groups connected under a larger network. Image via villageinsights.com

Currently, Ramirez says Village Insights is targeting all the major players within innovation — startup development organizations, incubators, accelerators, academic partners, and more — to both house their internal networks but also connect them to the greater innovation landscape for idea sharing and problem solving collaboration on the web-based app.

"It's an organizational network — you can bring your community together," Ramirez says. "And on top of that, we have social and productivity features. Really what we're trying to do is create collisions. We feel that innovation and solving problems is best done with a group — the village concept."

When the COVID-19 pandemic hit, the need for Village Insights became even greater.

"The world has changed," Ramirez says. "I feel like people are trying to find the right balance of the physical but also the productivity gain from being able to do things digitally."

But Village Insights — which grew throughout the pandemic, hiring a team Ramirez hadn't even met — isn't just a pandemic solution, nor is Ramirez trying to replace in-person collisions.

"We want to be the digital mesh around the physical world," he says.

Sensing an opportunity amid the pandemic, Francis approached Halliburton Labs with his idea. Francis, founder and CEO of Nanotech was a member of the accelerator. Halliburton Labs and Village Insights collaborated to create a beta of the technology focused on clean energy innovation, called Constellation. The platform has been used by Halliburton's network and will be featured as a part of their Pitch Day event on Sept. 30.

"We learned a lot as a startup working with a corporate entity," Ramirez says. "We got to collaborate together and think about different ways to provide value for Constellation and the clean energy community. We learned that people are looking for a way to connect, and we're just now getting started on that journey."

Buoyed by the success with Constellation, Ramirez says Village Insights is in fundraising mode to support its growth. The company has plans for a $1 million seed round with a series A round to follow in the next eight to 12 months.

Andrew Ramirez and Mike Francis originally worked on a similar project 10 years ago. Photos courtesy

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Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

$1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
$922 million for the University of Houston System
$167 million for Texas Southern University
$10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
Created the Lake Houston Dredging and Maintenance District
Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.

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