Rice Business Plan Competition doles out $2M to 2025 student teams

big winners

The University of Michigan's Intero Biosystems was the star of the show at the 2025 Rice Business Plan Competition, bringing home both the top-place finish and the largest total investment. Photo courtesy Rice University.

Celebrating its 25th year, the Rice Alliance for Technology and Entrepreneurship hosted the celebrated Rice Business Plan Competition this month, doling out more than $2 million in investment and cash prizes to the top-performing teams.

“For 25 years, the Rice Business Plan Competition has helped shape how Rice Business shows up in the world by creating a platform where student-entrepreneurs can tackle some of the most complex challenges of our time in energy, in health care, in technology and beyond,” Peter Rodriguez, dean of Rice Business, the presenting sponsor of the event, said in a news release. “If we’re serious about changing the world — and I believe we are — then it’s our responsibility to open doors for students everywhere to imagine bold solutions and build what comes next.”

Over the course of the three-day event, the 42 startups competing this year from colleges or universities around the world presented their plans before more than 300 angel, venture capital, and corporate investors. The teams were selected from the event’s largest applicant pool to date and represented 34 universities across four countries, according to Rice. Winners were announced at the company showcase and awards ceremony April 12 in downtown Houston.

Seven finalists were selected, though each team left the competition with some form of funding, according to Rice. The University of Michigan's Intero Biosystems was the star of the show, bringing home both the top-place finish and the largest total investment. Rice's own Pattern Materials also had a strong showing, placing fourth in the pitch competition and also earning the fourth-highest investment total.

Here are the teams that won big in 2025. See a full list of winners and prizes here.

Intero Biosystems, University of Michigan - $902,000

The team finished in first place for its GastroScreen, the first stem cell-driven human “mini gut” that is ideal for organ function testing before testing on humans, and also claimed the largest total investments among the competition.

$150,000 Goose Capital Investment Grand Prize
$250,000 Goose Capital Investment Prize
$200,000 The OWL Investment Prize
$100,000 Houston Angel Network Investment Prize
$100,000 nCourage Investment Network’s Courageous Women Entrepreneur Investment Prize
$100,000 Investment Prize from Nancy Chang
$1,000 Mercury Elevator Pitch Competition - Overall Winner
$1,000 Anbarci Family Company Showcase Prize
TMC Innovation Healthcare Accelerator Bootcamp Invitation Prize

MabLab, Harvard University – $301,500

The team placed second for its rapid test capable of detecting multiple adulterants in laced drugs and spiked drinks.

$100,000 Investment Prize, sponsored by David Anderson, Anderson Family Fund, Jon Finger and Finger Interests
$100,000 The Indus Entrepreneurs (TiE) Texas Angels Investment Prize
$25,000 nCourage Investment Network’s Courageous Women Entrepreneur Investment Prize
$50,000 Valhalla Investment Network Investment Prize
$25,000 The Eagles Investor Investment Prize
$500 Mercury Elevator Pitch Competition - Life Science*
$1,000 Anbarci Family Company Showcase Prize

re.solution, RWTH Aachen University — $76,500

The team placed third for its water-based technology that recycles polyesters without generating salt waste, making textile recycling viable.

$50,000 Investment Prize, sponsored by David Anderson, Anderson Family Fund, Jon Finger and Finger Interests
$25,000 Pearland EDC Spirit of Entrepreneurship Cash Prize
$500 Mercury Elevator Pitch Competition - Energy/Cleantech
$1,000 Anbarci Family Company Showcase Prize

Pattern Materials, Rice University – $134,500

The Houston-based team placed fourth for its laser-induced graphene technology that can be rapidly performed, enabling low-cost, scalable production of the material.

$5,000 prize, sponsored by Norton Rose Fulbright
$50,000 Valhalla Investment Network Investment Prize
$25,000 Pearland EDC Spirit of Entrepreneurship Cash Prize
$25,000 New Climate Ventures Sustainable Investment Prize
$25,000 Amentum and WRX Companies Rising Stars Space Technology and Commercial Aerospace Cash Prize
$500 Mercury Elevator Pitch Competition - Hard Tech
$1,000 Anbarci Family Company Showcase Prize
$3,000 Venture Builder Innovation Prizes

Xatoms, Western University and University of Toronto — $30,000

The team placed fifth for its AI- and quantum-driven platform for discovering solar-activated semiconductor materials.

$5,000 prize, sponsored by EY
$25,000 nCourage Investment Network’s Courageous Women Entrepreneur Investment Prize

Mito Robotics, Carnegie Mellon University— $5,000

The team placed sixth for its automated manual cell culture with AI-powered robotic scientists for life science research

$5,000 prize, sponsored by Chevron Technology Ventures

FarmSmart.ai, LSU – $106,000

The team placed seventh for its AI—driven assistant that synthesizes vast agricultural research into actionable, tailored intelligence, but earned the fifth-most investments among the group.

$5,000 prize, sponsored by Shell Ventures
$100,000 The OWL Investment Prize
$1,000 Anbarci Family Company Showcase Prize
Edward H. Molter Memorial Prizes for Wildcard Round - 1st place - Advance to Finals

Other significant awards

GreenLIB Materials, University of Ottawa – $152,000

$150,000 Goose Capital Investment Prize
$2,000 Venture Builder Innovation Prizes

Microvitality, Tufts University – $26,500

$25,000 Southwest National Pediatric Device Consortium Pediatric Device Cash Prize
$1,500 Edward H. Molter Memorial Prizes for Wildcard Round - 3rd place overall in WC

Nanoborne, University of Texas at Austin - $25,000

$25,000 NOV Golden Ticket to Supernova Accelerator and Cash Prize

Last year, the Rice Business Plan Competition facilitated over $1.5 million in investment and cash prizes. MesaQuantum from Harvard University landed the highest total investment last year, although it was not named a finalist. Protein Pints from Michigan State University won the pitch competition.

According to Rice, 910 startups have raised more than $6.9 billion in capital through the competition over the last 25 years.

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The winners of the hackathon included a contact tracing tool for schools, a soap dispenser to promote handwashing, a virus-killing filter, and more. Photo via Rice University Public Relations

College students design COVID-19 innovations at Rice University competition

coronavirus creations

As fall creeps closer, the need for a safe way to reopen schools becomes more and more dire. A team of Rice University students created a software that might help on that front.

SchoolTrace, a software that uses the schedules of students and faculty for COVID-19 contact tracing in schools, won top honors in the 2020 Rice Design-A-Thon, which took place July 17 to 19 online this year due to the pandemic. The hackathon was planned to be held in person during the fall semester, but organizers moved up the date to focus on coronavirus solutions. Twenty-three teams — comprised of 116 undergraduate competitors — participated.

"We wanted to provide students with a meaningful summer opportunity and the potential for a significant public health impact," says Carrigan Hudgins, a Sid Richardson College senior and co-coordinator, in a news release. "At one point, we considered cancelling, but hosting it virtually instead actually allowed us to reach a broader base of students across Texas and out of state."

SchoolTrace and its contact tracing tech that doesn't raise privacy concerns with tracking sensors or mobile phone apps took the $1,000 first price. Justin Cheung, Nick Glaze, Mit Mehta, Tyler Montague and Huzaifah Shamim — all juniors majoring in electrical and computer engineering — also received $500 for excelling in the digital age of health care track.

The teams that came in second and third place received $800 and $600, respectively, and the winners of each of the three design tracks also scored $500. The prizes were sponsored by Rice's George R. Brown School of Engineering, Rice's student chapter of the Biomedical Engineering Society and the Southwest National Pediatric Device Innovation Consortium.

Aside from the cash prizes, the students also received valuable guidances and feedback from industry experts.

"Having the judges and our team vouch for the actual solution, when we can propose it to different competitions and incubators around Texas and the country, is more important than the cash prizes," says co-coordinator Franklin Briones, a Brown College senior who competed in previous design-a-thons at Rice. Briones and Hudgins co-coordinated this year's event with Wiess College senior Eric Torres.

Here were the other award-winning innovations to come out of the program:

Second place and pediatric track winner — "Team SARS Wars: A New Hope." The team created a soap dispenser attachment that plays music and rewards children with stickers if they wash their hands for 20 seconds. Team members included: Anyssa Castorina, Aman Eujayl, Diego Lopez-Bernal, Janet Lu, Rubén Sebastián Marroquín, and Belén Szentes, all sophomores from Rice.
Third place — "The (d^3x/dt^3)(s)." COV-COM is a wall-mounted filtration system that catches and kills COVID-19 created by a team of juniors and seniors from the University of Texas at San Antonio. Team members included: Olivia Garza, Juan Herrera, Frida Montoya, Aishwarya Sathish, Samantha Strahan, and Morgan Struthers.
Global health track winner — "The Duncaroo Designers." The team from Rice created affordable desk partitions that could be used in schools with limited funds. Team members included: senior Rachel Bui and sophomores Jacob Duplantis, Charlie Gorton, Andrei Mitrofan, Anh Nguyen, and Vivian Wong.

Each of the teams were tasked Friday (July 17) evening with the prompt to "design and present a solution (either a product or a method) to address the treatment, prevention or non-medical related needs of the COVID-19 pandemic." Final presentations took place final presentations Sunday afternoon.

"The needs-finding for those problems was the most cumbersome part," Briones says in the release. "Not because it's hard to find problems, but because COVID-19 is so continually changing. It was hard to find which problem was the most important one."

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New cancer-fighting nanodrug tops Houston innovation news to know

Trending News

Editor's note: The new year brings big Houston innovation news, from pending retirements to new hires and a cancer-fighting nanodrug. Below are the five most-read InnovationMap stories published January 16-30, 2026:

1. Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

Wei Gao (center), a UH assistant professor of pharmacology, and her team have developed Nano-273, which helps the immune system fight pancreatic and lung cancers. Photo courtesy UH.

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within. Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum. Continue reading.

2. Rice Alliance and the Ion leader Brad Burke to retire this summer

Houston entrepreneurship and innovation leader Brad Burke is set to retire on June 30. Photo by Jeff Fitlow/Rice University

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university. Burke will remain at the Rice Alliance as an adviser until his retirement on June 30. Continue reading.

3. 5+ must-know application deadlines for Houston innovators

The University of Michigan's Intero Biosystems earned a top-place finish and the largest total investment from the 2025 Rice Business Plan Competition. Photo courtesy Rice University.

As 2026 ramps up, the Houston innovation scene is looking for the latest groups of innovative startups that'll make an impact. A number of accelerators and competitions have opened applications. See which might be a good fit for you or your venture, and take careful note of the deadlines. Continue reading.

4. Houston startups closed $1.75 billion in 2025 VC funding, says report

Local startups collected $1.75 billion in venture capital in 2025. Photo via Pexels.

Going against national trends, Houston-area startups raised 7 percent less venture capital last year than they did in 2024, according to the PitchBook-NVCA Venture Monitor report. The report shows local startups collected $1.75 billion in venture capital in 2025, down from $1.89 billion the previous year. Continue reading.

5. Baylor College of Medicine names Minnesota med school dean as new president, CEO

Baylor College of Medicine has named Dr. Jakub Tolar as its new president, CEO and executive dean. Photo courtesy of Mendel Lectures.

Dr. Jakub Tolar, dean of the University of Minnesota Medical School, is taking over as president, CEO and executive dean of Houston’s Baylor College of Medicine on July 1. Tolar—who’s also vice president for clinical affairs at the University of Minnesota and a university professor—will succeed Dr. Paul Klotman as head of BCM. Klotman is retiring June 30 after leading Texas’ top-ranked medical school since 2010. Continue reading.

Innovative Houston-area hardtech startup closes $5M seed round

fresh funding

Conroe-based hardtech startup FluxWorks has closed a $5 million seed round.

The funding was led by Austin-based Scout Ventures, which invests in early-stage startups working to solve national security challenges.

Michigan Capital Network also contributed to the round from its MCN Venture Fund V. The fund is one of 18 selected by the Department of Defense and Small Business Administration to participate in the Small Business Investment Company Critical Technologies Initiative, which will invest $4 billion into over 1,700 portfolio companies.

FluxWorks reports that it will use the funding to drive the commercialization of its flagship Celestial Gear technology.

"At Scout, we invest in 'frontier tech' that is essential to national interest. FluxWorks is doing exactly that by solving critical hardware bottlenecks with its flagship Celestial Gear technology ... This is about more than just gears; it’s about strengthening our industrial infrastructure," Scout Ventures shared in a LinkedIn post.

Fluxworks specializes in making contactless magnetic gears for use in extreme conditions, which can enhance in-space manufacturing. Its contactless design leads to less wear, debris and maintenance. Its technology is particularly suited for space applications because it does not require lubricants, which can be difficult to control at harsh temperatures and in microgravity.

The company received a grant from the Texas Space Commission last year and was one of two startups to receive the Technology in Space Prize, funded by Boeing and the Center for the Advancement of Science in Space (CASIS), in 2024. It also landed $1.2 million through the National Science Foundation's SBIR Phase II grant this fall.

Fluxworks was founded in College Station by CEO Bryton Praslicka in 2021. Praslicka moved the company to Conroe 2024.

5 Houston scientists named winners of prestigious Hill Prizes 2026

prized research

Five Houston scientists were recognized for their "high-risk, high-reward ideas and innovations" by Lyda Hill Philanthropies and the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST).

The 2026 Hill Prizes provide seed funding to top Texas researchers. This year's prizes were given out in seven categories, including biological sciences, engineering, medicine, physical sciences, public health and technology, and the new artificial intelligence award.

Each recipient’s institution or organization will receive $500,000 in direct funding from Dallas-based Lyda Hill Philanthropies. The organization has also committed to giving at least $1 million in discretionary research funding on an ad hoc basis for highly-ranked applicants who were not selected as recipients.

“It is with great pride that I congratulate this year’s Hill Prizes recipients. Their pioneering spirit and unwavering dedication to innovation are addressing some of the most pressing challenges of our time – from climate resilience and energy sustainability to medical breakthroughs and the future of artificial intelligence,” Lyda Hill, founder of Lyda Hill Philanthropies, said in a news release.

The 2026 Houston-area recipients include:

Biological Sciences: Susan M. Rosenberg, Baylor College of Medicine

Rosenberg and her team are developing ways to fight antibiotic resistance. The team will use the funding to screen a 14,000-compound drug library to identify additional candidates, study their mechanisms and test their ability to boost antibiotic effectiveness in animal models. The goal is to move toward clinical trials, beginning with veterans suffering from recurrent infections.

Medicine: Dr. Raghu Kalluri, The University of Texas MD Anderson Cancer Center

Kalluri is developing eye drops to treat age-related macular degeneration (AMD), the leading cause of vision loss globally. Kalluri will use the funding to accelerate studies and support testing for additional ocular conditions. He was also named to the National Academy of Inventors’ newest class of fellows last month.

Engineering: Naomi J. Halas, Rice University

Co-recipeints: Peter J. A. Nordlander and Hossein Robatjazi, Rice University

Halas and her team are working to advance light-driven technologies for sustainable ammonia synthesis. The team says it will use the funding to improve light-driven catalysts for converting nitrogen into ammonia, refine prototype reactors for practical deployment and partner with industry collaborators to advance larger-scale applications. Halas and Nordlander are co-founders of Syzygy Plasmonics, and Robatjazi serves as vice president of research for the company.

The other Texas-based recipients include:

Artificial Intelligence: Kristen Grauman, The University of Texas at Austin
Physical Sciences: Karen L. Wooley, Texas A&M University; Co-Recipient: Matthew Stone, Teysha Technologies
Public Health: Dr. Elizabeth C. Matsui, The University of Texas at Austin and Baylor College of Medicine
Technology: Kurt W. Swogger, Molecular Rebar Design LLC; Co-recipients: Clive Bosnyak, Molecular Rebar Design, and August Krupp, MR Rubber Business and Molecular Rebar Design LLC

Recipients will be recognized Feb. 2 during the TAMEST 2026 Annual Conference in San Antonio. They were determined by a committee of TAMEST members and endorsed by a committee of Texas Nobel and Breakthrough Prize Laureates and approved by the TAMEST Board of Directors.

“On behalf of TAMEST, we are honored to celebrate the 2026 Hill Prizes recipients. These outstanding innovators exemplify the excellence and ambition of Texas science and research,” Ganesh Thakur, TAMEST president and a distinguished professor at the University of Houston, added in the release. “Thanks to the visionary support of Lyda Hill Philanthropies, the Hill Prizes not only recognize transformative work but provide the resources to move bold ideas from the lab to life-changing solutions. We are proud to support their journeys and spotlight Texas as a global hub for scientific leadership.”

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