Rice Business Plan Competition doles out $2M to 2025 student teams

big winners

The University of Michigan's Intero Biosystems was the star of the show at the 2025 Rice Business Plan Competition, bringing home both the top-place finish and the largest total investment. Photo courtesy Rice University.

Celebrating its 25th year, the Rice Alliance for Technology and Entrepreneurship hosted the celebrated Rice Business Plan Competition this month, doling out more than $2 million in investment and cash prizes to the top-performing teams.

“For 25 years, the Rice Business Plan Competition has helped shape how Rice Business shows up in the world by creating a platform where student-entrepreneurs can tackle some of the most complex challenges of our time in energy, in health care, in technology and beyond,” Peter Rodriguez, dean of Rice Business, the presenting sponsor of the event, said in a news release. “If we’re serious about changing the world — and I believe we are — then it’s our responsibility to open doors for students everywhere to imagine bold solutions and build what comes next.”

Over the course of the three-day event, the 42 startups competing this year from colleges or universities around the world presented their plans before more than 300 angel, venture capital, and corporate investors. The teams were selected from the event’s largest applicant pool to date and represented 34 universities across four countries, according to Rice. Winners were announced at the company showcase and awards ceremony April 12 in downtown Houston.

Seven finalists were selected, though each team left the competition with some form of funding, according to Rice. The University of Michigan's Intero Biosystems was the star of the show, bringing home both the top-place finish and the largest total investment. Rice's own Pattern Materials also had a strong showing, placing fourth in the pitch competition and also earning the fourth-highest investment total.

Here are the teams that won big in 2025. See a full list of winners and prizes here.

Intero Biosystems, University of Michigan - $902,000

The team finished in first place for its GastroScreen, the first stem cell-driven human “mini gut” that is ideal for organ function testing before testing on humans, and also claimed the largest total investments among the competition.

  • $150,000 Goose Capital Investment Grand Prize
  • $250,000 Goose Capital Investment Prize
  • $200,000 The OWL Investment Prize
  • $100,000 Houston Angel Network Investment Prize
  • $100,000 nCourage Investment Network’s Courageous Women Entrepreneur Investment Prize
  • $100,000 Investment Prize from Nancy Chang
  • $1,000 Mercury Elevator Pitch Competition - Overall Winner
  • $1,000 Anbarci Family Company Showcase Prize
  • TMC Innovation Healthcare Accelerator Bootcamp Invitation Prize

MabLab, Harvard University – $301,500

The team placed second for its rapid test capable of detecting multiple adulterants in laced drugs and spiked drinks.

  • $100,000 Investment Prize, sponsored by David Anderson, Anderson Family Fund, Jon Finger and Finger Interests
  • $100,000 The Indus Entrepreneurs (TiE) Texas Angels Investment Prize
  • $25,000 nCourage Investment Network’s Courageous Women Entrepreneur Investment Prize
  • $50,000 Valhalla Investment Network Investment Prize
  • $25,000 The Eagles Investor Investment Prize
  • $500 Mercury Elevator Pitch Competition - Life Science*
  • $1,000 Anbarci Family Company Showcase Prize

re.solution, RWTH Aachen University — $76,500

The team placed third for its water-based technology that recycles polyesters without generating salt waste, making textile recycling viable.

  • $50,000 Investment Prize, sponsored by David Anderson, Anderson Family Fund, Jon Finger and Finger Interests
  • $25,000 Pearland EDC Spirit of Entrepreneurship Cash Prize
  • $500 Mercury Elevator Pitch Competition - Energy/Cleantech
  • $1,000 Anbarci Family Company Showcase Prize

Pattern Materials, Rice University – $134,500

The Houston-based team placed fourth for its laser-induced graphene technology that can be rapidly performed, enabling low-cost, scalable production of the material.

  • $5,000 prize, sponsored by Norton Rose Fulbright
  • $50,000 Valhalla Investment Network Investment Prize
  • $25,000 Pearland EDC Spirit of Entrepreneurship Cash Prize
  • $25,000 New Climate Ventures Sustainable Investment Prize
  • $25,000 Amentum and WRX Companies Rising Stars Space Technology and Commercial Aerospace Cash Prize
  • $500 Mercury Elevator Pitch Competition - Hard Tech
  • $1,000 Anbarci Family Company Showcase Prize
  • $3,000 Venture Builder Innovation Prizes

Xatoms, Western University and University of Toronto — $30,000

The team placed fifth for its AI- and quantum-driven platform for discovering solar-activated semiconductor materials.

  • $5,000 prize, sponsored by EY
  • $25,000 nCourage Investment Network’s Courageous Women Entrepreneur Investment Prize

Mito Robotics, Carnegie Mellon University— $5,000

The team placed sixth for its automated manual cell culture with AI-powered robotic scientists for life science research

  • $5,000 prize, sponsored by Chevron Technology Ventures

FarmSmart.ai, LSU – $106,000

The team placed seventh for its AI—driven assistant that synthesizes vast agricultural research into actionable, tailored intelligence, but earned the fifth-most investments among the group.

  • $5,000 prize, sponsored by Shell Ventures
  • $100,000 The OWL Investment Prize
  • $1,000 Anbarci Family Company Showcase Prize
  • Edward H. Molter Memorial Prizes for Wildcard Round - 1st place - Advance to Finals


Other significant awards

GreenLIB Materials, University of Ottawa – $152,000

  • $150,000 Goose Capital Investment Prize
  • $2,000 Venture Builder Innovation Prizes

Microvitality, Tufts University – $26,500

  • $25,000 Southwest National Pediatric Device Consortium Pediatric Device Cash Prize
  • $1,500 Edward H. Molter Memorial Prizes for Wildcard Round - 3rd place overall in WC

Nanoborne, University of Texas at Austin - $25,000

  • $25,000 NOV Golden Ticket to Supernova Accelerator and Cash Prize

Last year, the Rice Business Plan Competition facilitated over $1.5 million in investment and cash prizes. MesaQuantum from Harvard University landed the highest total investment last year, although it was not named a finalist. Protein Pints from Michigan State University won the pitch competition.

According to Rice, 910 startups have raised more than $6.9 billion in capital through the competition over the last 25 years.

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The winners of the hackathon included a contact tracing tool for schools, a soap dispenser to promote handwashing, a virus-killing filter, and more. Photo via Rice University Public Relations

College students design COVID-19 innovations at Rice University competition

coronavirus creations

As fall creeps closer, the need for a safe way to reopen schools becomes more and more dire. A team of Rice University students created a software that might help on that front.

SchoolTrace, a software that uses the schedules of students and faculty for COVID-19 contact tracing in schools, won top honors in the 2020 Rice Design-A-Thon, which took place July 17 to 19 online this year due to the pandemic. The hackathon was planned to be held in person during the fall semester, but organizers moved up the date to focus on coronavirus solutions. Twenty-three teams — comprised of 116 undergraduate competitors — participated.

"We wanted to provide students with a meaningful summer opportunity and the potential for a significant public health impact," says Carrigan Hudgins, a Sid Richardson College senior and co-coordinator, in a news release. "At one point, we considered cancelling, but hosting it virtually instead actually allowed us to reach a broader base of students across Texas and out of state."

SchoolTrace and its contact tracing tech that doesn't raise privacy concerns with tracking sensors or mobile phone apps took the $1,000 first price. Justin Cheung, Nick Glaze, Mit Mehta, Tyler Montague and Huzaifah Shamim — all juniors majoring in electrical and computer engineering — also received $500 for excelling in the digital age of health care track.

The teams that came in second and third place received $800 and $600, respectively, and the winners of each of the three design tracks also scored $500. The prizes were sponsored by Rice's George R. Brown School of Engineering, Rice's student chapter of the Biomedical Engineering Society and the Southwest National Pediatric Device Innovation Consortium.

Aside from the cash prizes, the students also received valuable guidances and feedback from industry experts.

"Having the judges and our team vouch for the actual solution, when we can propose it to different competitions and incubators around Texas and the country, is more important than the cash prizes," says co-coordinator Franklin Briones, a Brown College senior who competed in previous design-a-thons at Rice. Briones and Hudgins co-coordinated this year's event with Wiess College senior Eric Torres.

Here were the other award-winning innovations to come out of the program:

  • Second place and pediatric track winner — "Team SARS Wars: A New Hope." The team created a soap dispenser attachment that plays music and rewards children with stickers if they wash their hands for 20 seconds. Team members included: Anyssa Castorina, Aman Eujayl, Diego Lopez-Bernal, Janet Lu, Rubén Sebastián Marroquín, and Belén Szentes, all sophomores from Rice.
  • Third place — "The (d^3x/dt^3)(s)." COV-COM is a wall-mounted filtration system that catches and kills COVID-19 created by a team of juniors and seniors from the University of Texas at San Antonio. Team members included: Olivia Garza, Juan Herrera, Frida Montoya, Aishwarya Sathish, Samantha Strahan, and Morgan Struthers.
  • Global health track winner — "The Duncaroo Designers." The team from Rice created affordable desk partitions that could be used in schools with limited funds. Team members included: senior Rachel Bui and sophomores Jacob Duplantis, Charlie Gorton, Andrei Mitrofan, Anh Nguyen, and Vivian Wong.

Each of the teams were tasked Friday (July 17) evening with the prompt to "design and present a solution (either a product or a method) to address the treatment, prevention or non-medical related needs of the COVID-19 pandemic." Final presentations took place final presentations Sunday afternoon.

"The needs-finding for those problems was the most cumbersome part," Briones says in the release. "Not because it's hard to find problems, but because COVID-19 is so continually changing. It was hard to find which problem was the most important one."

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Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

5+ must-know application deadlines for Houston innovators

apply now

Editor's note: As 2026 ramps up, the Houston innovation scene is looking for the latest groups of innovative startups that'll make an impact. A number of accelerators and competitions have opened applications. Read below to see which might be a good fit for you or your venture. And take careful note of the deadlines. Please note: this article may be updated to include additional information and programs.

Did we miss an accelerator or competition accepting applications? Email innoeditor@innovationmap.com for editorial consideration.

2026 HCC Business Plan Competition

Deadline: Jan. 26

Details: HCC’s annual Business Plan Competition (BPC) is an opportunity for proposed, startup and existing entrepreneurs to develop focused plans to start or grow their businesses. Accepted teams will be announced and training will begin in late February and run through early June, with six free, three-hour training sessions. Advising will be provided to each accepted team. Applicants can apply as a team of up to five persons. Finalists will present to to gudges on May 27, 2026. Last year, $26,000 was awarded in seed money to the top five teams. In-kind prizes were also awarded to all graduating teams including free products, services and memberships, with an estimated in-kind value totaling $147,000. Find more information here.

University of Houston Technology Bridge Innov8 Hub (Spring 2026)

Deadline: Jan . 30

Details: UHTB Innov8 Hub’s immersive, 12-week startup acceleration program designed to help early-stage founders launch and scale their technology startups. Selected participants will gain access to expert mentors and advisors, collaborate with a cohort of peers, and compete for cash prizes during our final pitch event. The cohort begins Feb. 16, 2026. The program culminates in Pitch Day, where participants present their ventures to an audience of investors and partners from across the UH innovation ecosystem. Find more information here.

Rice Business Plan Competition 2026

Deadline: Jan. 31

Details: The Rice Business Plan Competition, hosted by the Rice Alliance for Technology and Entrepreneurship, gives collegiate entrepreneurs real-world experience to pitch their startups, enhance their business strategy and learn what it takes to launch a successful company. Forty-two teams will compete for more than $1 million in cash, investments and prizes on April 9-11, 2026. Find more information here.

Rice Veterans Business Battle 2026

Deadline: Jan. 31

Details: The Rice Veterans Business Battle is one of the nation’s largest pitch competitions for veteran-led startups, providing founders with mentorship, exposure to investors and the opportunity to compete for non-dilutive cash prizes. The event has led to more than $10 million of investments since it began in 2015. Teams will compete April 8-9, 2026. Find more information here.

TEX-E Fellows Application 2026-2027

Deadline: Feb. 10

Details: The TEX‑E Fellowship is a hands-on program designed for students interested in energy, climate, and entrepreneurship across Texas. It connects participants with industry mentors, startup founders, investors and academic leaders while providing practical, "real-world" experience in customer discovery, business modeling, and energy-transition innovation. Fellows gain access to workshops, real-world projects, and a statewide network shaping the future of energy and climate solutions. Participants must be a student at PVAMU, UH, UT Austin, Rice University, MIT or Texas A&M. Find more information here.

2026 Energy Venture Day & Pitch Competition

Deadline: Feb. 13

Details: The Rice Alliance, the Houston Energy Transition Initiative (HETI) and TEX-E will present the annual Energy Venture Day and Pitch Competition during CERAWeek on March 24-25, 2026. Energy Venture Day features two days of presentations by energy tech ventures driving efficiency and advancements toward the energy transition. On March 24, the Pitch Preview at the Ion will feature over 50 companies presenting in front of Rice Alliance's robust network of investors and industry partners. On March 25, the Energy Venture Day and Pitch Competition during CERAWeek will showcase 36 ventures at the George R Brown Convention Center. The pitch competition is divided up into the TEX-E university track, in which Texas student-led energy startups compete for $50,000 in cash prizes, and the industry ventures track. The industry track is subdivided into three additional tracks, spanning materials to clean energy. The top three companies from each industry track will be named. The winner of the CERAWeek competition will also have the chance to advance and compete for the $1 million investment prize at the Startup World Cup. Find more information here.

Greentown Go Make 2026

Deadline: March 10

Details: Greentown Go Make 2026 is an open-innovation program with Shell and Technip Energies. The six-month program is advancing industrial decarbonization by accelerating catalytic innovations. Selected startups will gain access to a structured platform to engage leadership from Shell and Technip Energies and explore potential partnership outcomes, including pilots and demonstrations. They’ll also receive networking opportunities, partnership-focused programming, and marketing visibility throughout the program. The cohort will be selected in May. Find more information here.

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