new digs

Photos: Rice Alliance reveals new office space

The Rice Alliance unveiled its new Gensler-designed, 3,000-square-foot office space. Photo courtesy of the Rice Alliance

Rice University's entrepreneurship-driving entity has a new, updated office on campus. The Rice Alliance for Technology and Entrepreneurship cut the ribbon on its 3,000-square-foot Bill and Stephanie Sick Suite just in time for the holidays.

The space was made possible by a $1 million donation from its namesake couple, Rice engineering alumnus William "Bill" Sick and his wife, Stephanie. Bill Sick was among the first supporters and mentors to the program when it was formed in 2000.

"[Bill is] passionate about building entrepreneurship at Rice University and passionate about the importance of entrepreneurship in driving innovation and economic development in this country," Brad Burke, managing director at the alliance, says. "Bill has watched Rice's program go from an unranked program to the No. 1 entrepreneurship program in the country and felt the Rice Alliance needed a larger, more appropriate space commensurate with the Rice Alliance's impact on Rice and on the Houston community."

Burke says the Rice Alliance's new home — located in McNair Hall, which houses the Jones Graduate School of Business — will be better accommodating for the number of industry professionals that come onto the Rice campus for events, programming, mentorship, and more.

"The Rice Alliance meets frequently with venture capitalists, entrepreneurs, students, mentors, and other members of the Houston entrepreneurial ecosystem," Burke says. "The new space is on the first floor of the Jones School and is much more accessible and visible to our guests and visitors."

The Bill and Stephanie Sick Suite has doubled the Alliance's space and has allowed the organization to co-locate with another innovation-focus entity on campus. The Liu Idea Lab for Innovation & Entrepreneurship, or LILIE, will have an office in the space, better connecting the two organizations that have worked hand-in-hand for a number of years.

Some visual elements of the space include bright green walls, which sets the Rice Alliance apart from the school with an energetic feel. The space also features a number of Houston art, including:

  • A three-paneled piece by local Houston artist DUAL, which was commissioned by Rice Alliance for the 2019 Rice Business Plan Competition.
  • A neon sign, designed and created by Houston artist Tim Walker of The Neon Gallery adorns the entrance wall.
  • In a way to honor Houston's history, mosaic tile flooring from the Blue Tile Project is also featured in the space.

Gensler designed the space and b. bell builders was the general contractor. Quynhmai Nguyen, Rice Alliance's senior director of operations and event planning, worked with Gensler and made the final detailed design decisions.

Energetic new space

The new space, which premiered with a holiday party last week, features a neon sign, designed and created by Houston artist Tim Walker of The Neon Gallery.

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Building Houston

 
 

From biomolecular research to oral cancer immunotherapy, here are three research projects to watch out for in Houston. Photo via Getty Images

Research, perhaps now more than ever, is crucial to expanding and growing innovation in Houston — and it's happening across the city right under our noses.

In InnovationMap's latest roundup of research news, a couple local scientists are honored by awards while another duo of specialists tackle a new project.

University of Houston professor recognized with award

Mehmet Orman of UH has been selected to receive an award for his research on persister cells. Photo via UH.edu

Mehmet Orman, assistant professor of chemical and biomolecular engineering at the University of Houston Cullen College of Engineering has been honored with a Faculty Early Career Development Award from the National Science Foundation. The award comes with a $500,000 grant to study persister cells — cells that go dormant and then become tolerant to extraordinary levels of antibiotics.

"Nearly all bacterial cultures contain a small population of persister cells," says Orman in a news release. "Persisters are thought to be responsible for recurring chronic infections such as those of the urinary tract and for creating drug-resistant mutants."

Previously, Orman developed the first methods to directly measure the metabolism of persister cells. He also developed cell sorting strategies to segregate persisters from highly heterogeneous bacterial cell populations, and, according to the release, he will be using his methods in the NSF research project.

Houston researchers collaborate on oral cancer innovation

Dr. Simon Young of UTHealth and Jeffrey Hartgerink of Rice University are working on a new use for an innovative gel they developed. Photo via Rice.edu

Two Houston researchers — chemist and bioengineer Jeffrey Hartgerink at Rice University and Dr. Simon Young at the University of Texas Health Science Center at Houston — have again teamed up to advance their previous development of a sophisticated hydrogel called STINGel. This time, they are using it to destroy oral cancer tumors.

SynerGel combines a pair of antitumor agents into a gel that can be injected directly into tumors. Once there, the gel controls the release of its cargo to not only trigger cells' immune response but also to remove other suppressive immune cells from the tumor's microenvironment. The duo reported on the technology in the American Chemical Society journal ACS Biomaterials Science & Engineering.

SynerGel, combines a pair of antitumor agents into a gel that can be injected directly into tumors, where they not only control the release of the drugs but also remove suppressive immune cells from the tumor's microenvironment.

"We are really excited about this new material," Hartgerink says in a news release. "SynerGel is formulated from a specially synthesized peptide which itself acts as an enzyme inhibitor, but it also assembles into a nanofibrous gel that can entrap and release other drugs in a controlled fashion.

In 2018, the pair published research on the use of a multidomain peptide gel — the original STINGel — to deliver ADU-S100, an immunotherapy drug from a class of "stimulator of interferon gene (STING) agonists."

The research is supported by the Oral and Maxillofacial Surgery Foundation, the National Institutes of Health, the Welch Foundation, the National Science Foundation and the Mexican National Council for Science and Technology.

Texas Heart Institute researcher honored by national organization

Dr. James Martin of Texas Heart Institute has been named a senior member of the National Academy of Inventors. Photo courtesy of THI

The National Academy of Inventors have named Houston-based Texas Heart Institute's Dr. James Martin, director of the Cardiomyocyte Renewal Lab, a senior member.

Martin is an internationally recognized developmental and regenerative biologist and his research is focused on understanding how signaling pathways are related to development and tissue regeneration.

"Dr. Martin has long been a steward of scientific advancement and has proven to be a tremendous asset to the Texas Heart Institute and to its Cardiomyocyte Renewal Lab through his efforts to translate fundamental biological discoveries in cardiac development and disease into novel treatment strategies for cardiac regeneration," says Dr. Darren Woodside, vice president for research at THI, in a news release. "Everyone at the Texas Heart Institute is thrilled for Dr. Martin, whose induction into the NAI as a Senior Member is well-deserved."

Martin has authored over 170 peer-reviewed papers in top journals he holds nine U.S. patents and applications, including one provisional application, all of which have been licensed to Yap Therapeutics, a company he co-founded.

The full list of incoming NAI Senior Members, which includes three professionals from the University of Houston, is available on the NAI website.

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