Zach Ellis, founder and general partner of South Loop Ventures, which recently closed its debut fund. Photo via LinkedIn

Houston-based South Loop Ventures recently closed its debut fund for more than $21 million, led by investments from Rice Management Company and Chevron Technology Ventures.

The funds will go toward teams with at least one underrepresented founder of color working in the energy, health, space, sports and fintech sectors. Additional investments came from The Great Commission Foundation of the Episcopal Diocese of Texas, Texas CapitalBank and others organizations.

According to South Loop Ventures, less than 3 percent of venture capital reaches underrepresented founders of color. Zach Ellis Jr., founder and general partner of South Loop, says the firm wants to address this "billion-dollar blind spot."

"Inequitable distribution of venture capital represents a clear market inefficiency—and market inefficiencies translate into exceptional opportunities," Ellis said in a release.

He added that the firm's location in Houston will help it make an impact.

"Being anchored here gives us front-row access to world-class corporations eager to engage and support innovation from founders with underrepresented voices and perspectives," he added in the release.

Ellis founded South Loop Ventures in 2022. It has funded 13 companies since August 2023 and plans to fund several more this year. Its portfolio includes Houston-based Milkify, a breast milk freeze-drying service; Lokum App, a Houston-founded platform for recruiting certified registered nurse anesthetists; and others.

Ellis' background spans the United States Military, academia, and roles at Rev1 Ventures and PepsiCo’s corporate venture team. He previously told InnovationMap that he was called to invest in founders of color after George Floyd's murder. He says he also realized how much money was being left on the table by overlooking these innovators.

"The mission of South Loop is to become the preeminent source of venture capital dollars for underrepresented, diverse teams nationally to serve as a beacon for the best underrepresented talent and to enable them to be successful through leveraging the unique resources and talent of Houston," he said on the Houston Innovators Podcast in 2024. "A big part of our mission is also to help catalyze Houston as an ecosystem for tech entrepreneurship."

Listen to the full interview with Ellis here. The recent funding news and Ellis were also featured in a profile by TechCrunch earlier this week. Click here to read more.

The Ion has announced that it is adding an additional 28,000 square feet of coworking space. Photo courtesy of the Ion

Houston innovation hub expands coworking space

more room at the Ion

The Ion has announced it will bring more coworking space to its facility.

The innovation hub in Midtown, which is owned and operated by Rice Management Company, expanded its partnership with Dallas-based Common Desk to the Ion’s fourth floor. The addition brings another 28,000 square feet of workspace to the building.

“When people work in an inspiring place that fosters community, going into work is exciting. The Ion’s experience with Common Desk proves it,” says Jan E. Odegard, executive director of the Ion. “This rapid expansion signals that the Ion is the place to be for growing organizations, and we will soon be releasing new programs that expand our value proposition for startups, investors, corporations, academic institutions, and the community.”

According to the release, Common Desk's Ion space — originally opened in August of 2021 — reached max capacity in less than a year and now has a waiting list. The new combined space will total 86,400 square feet of coworking space for Houston entrepreneurs.

"With RMC’s support, we created a thoughtful design, along with the amenities and memberships offered,” says Common Desk's Head of Real Estate Dawson Williams in the release. “One year later, this space in the Ion is a game-changer for Houston’s innovators. It’s exciting that we’re already expanding because so many rapidly growing companies want to be inside the Ion and experience everything it has to offer.”

Founded in 2012, Common Desk has grown to over 20 locations and counting in Dallas, Houston, Austin, Wilmington, and Raleigh. In Houston, the company has opened coworking space in several locations, most recently at the POST in downtown.

The Ion's Common Desk space originally opened last summer. Rendering courtesy of Common Desk

This week's roundup of Houston innovators includes Sam Dike of Rice Management Company, Barbara Burger of Greentown Labs, and Joe Alapat of Liongard. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from clean energy to software — recently making headlines in Houston innovation.


Sam Dike, manager of strategic initiatives at Rice Management Company

Sam Dike of Rice Management Company joins the Houston Innovators Podcast to discuss the past, present, and future of Houston's rising Ion Innovation District. Photo via rice.edu

A few years ago, Rice Management Company saw an opportunity a few years back to make an investment in Houston's nascent innovation and tech ecosystem, and announced the plans for the Ion, a 266,000-square-foot innovation hub in an renovated and rehabilitated Sears.

"In some ways innovation is not necessarily about creating something completely new — it's oftentimes building upon something that exists and making it better," says Sam Dike, manager of strategic initiatives at Rice Management Company, on the most recent episode of the Houston Innovators Podcast. "I think that's what we've done with the building itself.

"We took something that had really strong bones and a strong identity here in Houston," he continues, "and we did something that's often atypical in Houston and preserved and repurposed it — not an easy logistical or financial decision to make, but we believed it was the best for Houston and for the project." Click here to read more and stream the podcast.

Barbara Burger, board member at Greentown Labs

Barbara Burger, former president of Chevron Technology Ventures, has been named to the Greentown Labs board of directors. Photo courtesy of CTV

Greentown Labs announced that it has appointed Barbara J. Burger — former vice president of innovation and president of Chevron Technology Ventures, Chevron's startup investment arm — to its board of directors.

In her previous role at Chevron, she spearheaded the energy company's support of Greentown Labs since 2013 and the opening of its Houston incubator. After announcing her retirement in December, she has continued being active at Greentown and hosts semi-annual Women of Greentown Houston dinners.

“I am honored and excited to join the Greentown Labs Board of Directors,” says Burger in the release. “Combatting the effects of climate change requires bringing a wide range of innovative solutions to scale. There is work for incumbents and startups alike in this enormous challenge that WE all face. Greentown Labs plays an essential role in providing facilities, tools, programs, and an inclusive community to nurture and grow innovation that matters.” Click here to continue reading.

Joe Alapat, co-founder and CEO of Liongard

Houston IT company forms new partnership

Houston-based Liongard has fresh funding to work with. Courtesy of Liongard

Liongard, an IT software provider, has raised an additional $10 million in funding, according to a news release, will go toward providing the best customer service for Liongard's growing customer base.

The technology is providing managed service providers, or MSPs, improved visibility across the IT stack and an optimized user experience.

“Since working with our first MSP partners, we’ve seen time and again the power of visibility into IT data, reducing the time they spend researching customer issues and allowing them to respond faster than their peers,” says Joe Alapat, CEO and co-founder of Liongard, in the release. “This investment enables us to continue to achieve our vision of delivering visibility into each element of the IT stack.” Click here to continue reading.

Sam Dike of Rice Management Company joins the Houston Innovators Podcast to discuss the past, present, and future of Houston's rising Ion Innovation District. Photo via rice.edu

What Houston can expect from its rising innovation district

Houston innovators podcast episode 140

Last month, the Ion Houston welcomed in the greater Houston community to showcase the programs and companies operating within the Ion Innovation District — and the week-long Ion Activation Festival spotlighted just the beginning.

The rising district — anchored by the Ion — is a 16-acre project in Midtown Houston owned and operated by Rice Management Company, an organization focused on managing Rice University's $8.1 billion endowment.

"We're chiefly responsible for stewarding the university's endowment and generating returns to support the academic mission of the university," says Samuel Dike, manager of strategic initiatives at RMC, on this week's episode of the Houston Innovators Podcast. "Part of those returns go to support student scholarships and student success — as well as many of the other academic programs."

"The university sees a dual purpose behind the investing," Dike continues, in addition to focusing on generating returns, RMC's mission is "also to be a valuable partner in Houston's ecosystem and pushing Houston as a global 21st century city."

RMC saw an opportunity a few years back to make an investment in Houston's nascent innovation and tech ecosystem, and announced the plans for the Ion, a 266,000-square-foot innovation hub in an renovated and rehabilitated Sears.

"In some ways innovation is not necessarily about creating something completely new — it's oftentimes building upon something that exists and making it better," Dike says. "I think that's what we've done with the building itself.

"We took something that had really strong bones and a strong identity here in Houston," he continues, "and we did something that's often atypical in Houston and preserved and repurposed it — not an easy logistical or financial decision to make, but we believed it was the best for Houston and for the project."

Now, the Ion District includes the Ion as the anchor, as well as Greentown Houston, which moved into a 40,000-square-foot space in the former Fiesta Mart building, just down the street. While RMC has announced a few other initiatives, the next construction project to be delivered is a 1,500-space parking garage that will serve the district.

"It is not your typical parking garage," Dike says. "The garage will feature a vegetated facade with ground-floor retail and gallery space, as well as EV charging spaces and spaces to feature display spaces for future tech. It's going to be a nice addition to the district."

The new garage will free up surface parking lots that then will be freed up for future construction projects, Dike explains.

He shares more about the past, present, and future of the Ion and the district as a whole on the podcast. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.



The Ion has a new partner. Photo courtesy of The Ion

ExxonMobil named founding partner of Houston innovation hub

new collab

A Texas energy giant has joined The Ion as a founding partner, the innovation hub announced recently.

ExxonMobil, which announced its new Houston HQ move from Irving, Texas, earlier this year, celebrated the announcement at the Ion Activation Festival last month. The partnership is effective immediately, according to a June 13 news release.

“ExxonMobil has been a leader in energy technology for over a century. Collaboration is essential to both augment our capabilities and accelerate the development of scalable solutions,” says Linda DuCharme, president of ExxonMobil Technology and Engineering Company, in the release. “Our partnership with The Ion will enable us to tap into the extraordinary talent in Houston.”

ExxonMobil joins existing Ion founding partners Aramco, Chevron Technology Ventures, Baker Botts, and Microsoft, as well as affiliate partners bp and Intel. The company joins the Ion "to help develop solutions for the world’s emerging energy issues," per the release.

“To have one of the strongest brands in oil and gas globally join us is a testament to the Ion’s momentum and mission,” says Jan E. Odegard, executive director of the Ion. “We’re thrilled to welcome ExxonMobil’s thought leaders and this caliber of mindshare to the Ion family. As the Ion expands its programming and footprint, we are confident in the impact we’ll create together.”

The Ion is a 266,000-square-foot building developed and managed by Rice Management Company and anchors the 16-acre Innovation District in Midtown.

The Ion has joined the ranks of an international network of hotspots for innovation. Photo courtesy of The Ion

Houston's emerging innovation district gets global recognition from prestigious program

tech hotspot

The Ion Houston has a new feather to add to its cap. Rice Management Company's Midtown innovation hub has been recognized on a global scale.

The Global Network of Innovation Districts has added The Ion District to its network of innovation hubs, and the Ion is the first district in Texas to join. Affiliated with the Brookings Institute, the global organization consists of thought leaders and innovation district developers. With the addition of the Ion, there are 22 members in the Global Network, including the Pittsburgh Innovation District, Cortex Innovation Community in Missouri, Tech Central in Sydney, and Knowledge District Zuidas in Amsterdam.

“GIID’s Global Network is utilizing best practices of world-renowned innovation districts to accelerate regional economies. Their focus on placemaking, startup services, and community engagement are some of the critical components that lead to successful districts,” says Bryson Grover, investment manager of real estate development at Rice Management Company, in a news release. “With GIID, we will continue to think creatively about how the built environment and specialized programming can inform future development and allow equitable access to an ever-changing workforce.”

The Ion, a 266,000-square-foot space in the renovated Midtown Sears building, is the anchor of the district, which also includes Greentown Labs. According to the release, the next building is under construction, with three more projects to begin in the next year. Overall, the build-out of the Ion District will deliver three million square feet of development across 16 acres over the next decade.

“The Ion and the Ion District represent a major commitment and investment in the success of Houston as a center of innovation and a foundation of Houston’s economic future. From the very beginning of our planning, we visited innovation hubs and districts around the country and around the world to make sure that we drew on their experiences and best practices,” says Rice President David Leebron in the release. “And by participating in the Global Network now, the Ion District will contribute to and benefit from a global exchange of knowledge among the very best innovation districts, which complements Rice’s broader international engagements and strategies.”

GIID is a nonprofit dedicated to research on and connecting innovation districts in new geographies of innovation, per the release. Headquartered in New York, the organization was founded in 2018 to help position innovation districts as engines of economic development and spur productive, inclusive, and sustainable environments.

“We’re thrilled for The Ion and Ion District to join our network, especially as it commences its next steps on development later this year,” says Julia Wagner, president of GIID, in the release. “Our team has extensive experience working with unique real estate ventures that aim to transform how communities learn, work, and live. We look forward to playing a part in Houston’s transformation, and as we have documented in innovation districts around the world, having a leader like Rice drive the creation of the district is a key ingredient of its continued and growing success.”

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Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.

Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.

5 incubators and accelerators fueling the growth of Houston startups

meet the finalists

Houston is home to numerous accelerators and incubators that support founders in pushing their innovative startups and technologies forward.

As part of our 2025 Houston Innovation Awards, the new Incubator/Accelerator of the Year category honors a local incubator or accelerator that is championing and fueling the growth of Houston startups.

Five incubators and accelerators have been named finalists for the 2025 award. They support startups ranging from hard-tech companies to digital health startups.

Read more about these organizations below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled.

Get your tickets now on sale for this exclusive event celebrating Houston Innovation.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its second Houston cohort this summer.

This year, the incubator grew to include its largest number of concurrent supported fellows, with 88 companies currently being supported nationally. In total, Activate has supported 296 fellows who have created 236 companies. Those companies have raised over $4 billion in follow-on funding, according to Activate. In Houston, it has supported several Innovation Awards finalists, including Solidec, Bairitone Health and Deep Anchor Solutions. It is led locally by Houston Managing Director Jeremy Pitts.

EnergyTech Nexus

Cleantech startup hub EnergyTech Nexus' mission is to accelerate the energy transition by connecting founders, investors and industrial stakeholders and helping to develop transformative companies, known as "thunderlizards."

The hub was founded in 2023 by CEO Jason Ethier, Juliana Garaizar and Nada Ahmed. It has supported startups including Capwell Services, Resollant, Syzygy Plasmonics, Hertha Metals, EarthEn Energy and Solidec—many of which are current or past Innovation Awards finalists. This year Energy Tech Nexus launched its COPILOT Accelerator, powered by Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory (NREL). COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. Energy Tech Nexus also launched its Liftoff fundraising program, its Investor Program, and a "strategic ecosystem partnership" with Greentown Labs.

Greentown Labs

Climatetech incubator Greentown Labs offers its community resources and a network to climate and energy innovation startups looking to grow. The collaborative community offers members state-of-the-art prototyping labs, business resources and access to investors and corporate partners. The co-located incubator was first launched in Boston in 2011 before opening in Houston in 2021.

Greentown has seen major changes and activity this year. In February, Greentown announced Georgina Campbell Flatter as its new CEO, along with a new Board of Directors. In July, it announced Lawson Gow as its Head of Houston, a "dedicated role to champion the success of Greentown Houston’s startups and lead Greentown’s next chapter of impact in the region," according to Greentown. It has since announced numerous new partnerships, including those with Energy Tech Nexus, Los Angeles-based software development firm Nominal, to launch the new Industrial Center of Excellence; and Houston-based Shoreless, to launch an AI lab onsite. Greentown Houston has supported 175 startups since its launch in 2021, with 45 joining in the last two years. Those startups include the likes of Hertha Metals, RepAir Carbon, Solidec, Eclipse Energy (formerly GoldH2) and many others.

Healthtech Accelerator (TMCi)

The Healthtech Accelerator, formerly TMCx, focuses on clinical partnerships to improve healthcare delivery and outcomes. Emerging digital health and medical device startups that join the accelerator are connected with a network of TMC hospitals and seasoned advisors that will prepare them for clinical validation, funding and deployment.

The Healthtech Accelerator is part of Texas Medical Center Innovation, which also offers the TMCi Accelerator for Cancer Therapeutics. The Healthtech Accelerator named its 19th, and latest, cohort of 11 companies last month.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with 24,000-plus members spanning 69 countries, making it one of the world’s largest communities for accelerating entrepreneurial solutions toward the United Nations' Sustainable Development Goals (SDGs).

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.