4 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Angela Holmes of Mercury Data Science, Meredith Wheeler and Maggie Segrich of Sesh Coworking, and Shaun Zhang of the University of Houston. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from data science to cancer therapeutics — recently making headlines in Houston innovation.

Angela Holmes, CEO of Mercury Data Science

Angela Holmes is the CEO of MDS. Photo via mercuryds.com

A Houston-based AI solutions consultancy has made changes to its C-suite. Dan Watkins is passing on the CEO baton to Angela Holmes, who has served on MDS's board and as COO. As Holmes moves into the top leadership position, Watkins will transition to chief strategy officer and maintain his role on the board of directors.

"It is an exciting time to lead Mercury Data Science as we advance the development of innovative data science platforms at the intersection of biology, behavior, and AI," says Holmes in the release. "I am particularly excited about the demand for our Ergo insights platform for life sciences, allowing scientists to aggregate a vast set of biomedical data to better inform decisions around drug development priorities." Click here to read more.

Meredith Wheeler and Maggie Segrich, co-founders of Sesh Coworking

Sesh Coworking and its founders Maggie Segrich and Meredith Wheeler are on a roll. Photo courtesy of Sesh

Sesh Coworking, described as Houston’s first female-focused and LGBTQIA+ affirming coworking, has been operating its 2808 Caroline Street location's second-floor space since January, but the first floor, as of this week, is now open to membership and visitors. The new build-out brings the location to over 20,000 square feet of space.

Called The Parlor, the new space includes additional desks, common areas, a wellness room, and a retail pop-up space. Since its inception in early 2020, Sesh has overcome the pandemic-related obstacles in its path and even seen a 60 percent increase in membership with an overall 240 percent increase in sales over the past year.

“Our growth is a testament to the ever-changing landscape of Houston’s office and retail industry after the workplace dramatically changed in 2020,” says Maggie Segrich, co-founder of Sesh Coworking, in a news release. “We are ecstatic to welcome current and prospective members to our new, inclusive space.” Click here to read more.

The duo also joined the Houston Innovators Podcast to discuss Sesh's growth. Click here to listen.

Shaun Zhang, director of the Center for Nuclear Receptors and Cell Signaling at the University of Houston

A UH professor is fighting cancer with a newly created virus that targets the bad cells and leaves the good ones alone. Photo via UH.edu

A Houston researcher is developing a cancer treatment — called oncolytic virotherapy — that can kill cancer cells while being ineffective to surrounding cells and tissue. Basically, the virus targets the bad guys by "activating an antitumor immune response made of immune cells such as natural killer (NK) cells," according to a news release from the University of Houston.

However exciting this rising OV treatment seems, the early stage development is far from perfect. Shaun Zhang, director of the Center for Nuclear Receptors and Cell Signaling at the University of Houston, is hoping his work will help improve OV treatment and make it more effective.

“We have developed a novel strategy that not only can prevent NK cells from clearing the administered oncolytic virus, but also goes one step further by guiding them to attack tumor cells. We took an entirely different approach to create this oncolytic virotherapy by deleting a region of the gene which has been shown to activate the signaling pathway that enables the virus to replicate in normal cells,” Zhang says in the release. Click here to read more.

Sesh Coworking and its founders Maggie Segrich and Meredith Wheeler are on a roll. Photo courtesy of Sesh

With freshly opened inclusive coworking space, Houston founders look to continue momentum

houston innovators podcast episode 142

The origin story of Sesh Coworking is familiar to a lot of startups. Meredith Wheeler was looking for a new business opportunity — and the right network and work environment to do that — when she realized she didn't find anything out there that was what she needed. Then she thought — maybe building that was the next business opportunity she was looking for.

"I knew that I wanted each person who was introduced to our community felt unafraid," Wheeler says on this week's episode of the Houston Innovators Podcast. "It's really hard to walk into anywhere where anyone knows each other. I wanted it to feel to people that it was approachable."

Eventually relocating to Houston and syncing up with her now-business partner, Maggie Segrich, Wheeler started hosting pop-up coworking sessions. The meetups evolved into Sesh Coworking's small Montrose space that opened in early 2020.

This year, the duo got to have their dream of a bigger, inclusive coworking space actualized, and both phase one and two of the new Sesh Coworking space has opened in Midtown. Described as Houston’s first female-focused and LGBTQIA+ affirming coworking, Sesh's 2808 Caroline Street location provides its members with over 20,000 square feet of meeting, work, and event space.

With the bigger space, Wheeler and Segrich have the same mission of inclusivity and embracing diversity while growing its membership.

"At the end of the day, what our members really want is a feeling of belonging," Wheeler says. "They might need to get out of the house, and they might need to network a bit more. But what they want is a sense of belonging. Sesh provides that because we are this inclusive community."

Sesh, as the co-founders describe, is an attractive spot for creatives and business owners seeking a community and flexible environment. Membership is $199 a month for coworkers, and now, thanks to the expansion, Sesh also can provide private office space — even to coworker members.

"To jump into a private office — that's a big difference in pricing for some people, and that means that your business has to grow exponentially to get to that point," Segrich says. "So we try to make sure that all our members have access to private spaces for a few hours a day. We know that budgeting restraints are a big deal."

The Midtown location also has a similar opportunity for growing retail businesses. Just like the other members at Sesh, the shop gives retailers a smaller scale and less risky space compared to the costs associated with opening up their own brick-and-mortar shop.

With the challenges from the pandemic and the construction of the new store behind them, Segrich and Wheeler are already looking to the future for the company.

"First Houston — next, the world," Segrich says. "This location we've definitely set up to be the flagship, so there is definitely more Sesh coming whether that's in Houston, Texas, or somewhere else is yet to be determined.


Sesh's 20,000-square-foot space in Midtown is now completely open. Photo courtesy of Sesh

Photos: Houston coworking spot opens expanded first-floor space

where to work

A female-focused coworking space has officially opened the first floor of its Midtown Houston location after a months-long buildout.

Sesh Coworking, described as Houston’s first female-focused and LGBTQIA+ affirming coworking, has been operating its 2808 Caroline Street location's second-floor space since January, but the first floor, as of this week, is now open to membership and visitors. The new build-out brings the location to over 20,000 square feet of space.

Called The Parlor, the new space includes additional desks, common areas, a wellness room, and a retail pop-up space. Since its inception in early 2020, Sesh has overcome the pandemic-related obstacles in its path and even seen a 60 percent increase in membership with an overall 240 percent increase in sales over the past year.

“Our growth is a testament to the ever-changing landscape of Houston’s office and retail industry after the workplace dramatically changed in 2020,” says Maggie Segrich, co-founder of Sesh Coworking, in a news release. “We are ecstatic to welcome current and prospective members to our new, inclusive space.”

Sesh tapped real estate developer, The Deal Co, to work on the space and provide a catered experience for a diversified membership, including working mothers, the LGBTQIA+ community, and progressive Houstonians, per the news release.

The fully completed space now provides members with:

  • Hassle-free parking
  • 30 offices
  • Three conference rooms
  • Four phone booths
  • Amphitheater
  • Library
  • Studio kitchen
  • Pop-up retail shop for local small businesses
  • Locker rooms with showers
  • Interactive art installations
  • 24/7 access
  • Tech-enabled spaces
  • 15 percent at Weights + Measures, which directly connects to The Parlor

“Our vision is to provide a high-quality experience with a tight-knit community,” said Co-Founder Meredith Wheeler. “The Parlor’s open and collaborative atmosphere will help foster relationships, collaboration and creativity for our members.”

  

Photo courtesy of Sesh

This week's roundup of Houston innovators includes Dr. Toby Hamilton of Hamilton Health Box, Meredith Wheeler and Maggie Segrich of Sesh Coworking, and Simone Biles of Cerebral. Courtesy photos

4 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health to coworking — recently making headlines in Houston innovation.

Dr. Toby Hamilton, founder and CEO of Hamilton Health Box

Dr. Toby Hamilton is a leader in Houston's health care innovation ecosystem, and he joins the Houston Innovators Podcast to discuss his latest endeavor, which is rethinking primary and preventative care. Photo via tmc.edu

Dr. Toby Hamilton has seen Houston establish itself as a leader in health innovation, and he's been a part of that journey too. He started his career as a physician before founding Emerus Holdings, a micro-hospital system in the Houston area which later exited to private equity. He also founded a nonprofit focused on connecting hospital innovation leaders called the Healthcare Innovators Professional Society and led the Texas Medical Center's Biodesign program for two years.

Over the years, he says he's seen the potential develop for Houston to hold a significant role in health care innovation across the world — it's just going to take all hands on deck.

"As a community, if we can get behind that vision and be the place that tests, develops, and creates opportunities, Houston has the potential to be unlike anything in the world," he says on the Houston Innovators Podcast. Click here to listen and read more.

Meredith Wheeler and Maggie Segrich, founders of Sesh Coworking

Co-founders Maggie Segrich (right) opened Sesh with Meredith Wheeler in 2020. Photo courtesy of Sesh

One of Houston's coworking companies is moving on up. Sesh Coworking is moving into a new space that's 10 times as large as its original location — and it's an optimal location too, say Meredith Wheeler and Maggie Segrich, founders of Sesh Coworking.

"Being able to grow our community at our beautiful original location in Montrose through the pandemic is a testament to the grit and resilience of Houstonians. We are so honored and grateful to be a part of their journey,” says Segrich. “We are excited that our new location in Midtown, near the Innovation District, will provide more Houstonians with the workspace and support they need."

The two-story space is expected to open in two phases. Tenants will first move into the space's second floor in January while the first floor, the larger of the two floors, completes construction and is expected in March. Click here to read more.

Simone Biles, chief impact officer at Cerebral

Houston's favorite gymnast is the chief impact officer on a California-based tech company that's raised $462M. Photo via getcerebral.com

The greatest gymnast of all time has a new title to her many gymnastics accomplishments. Simone Biles recently joined mental health startup Cerebral as chief impact officer, and the company is backed by SoftBank and has a valuation of $4.8 billion.

Biles has been vocal about her passion for mental health. Cerebral was an official sponsor of Biles’ Gold Over America Tour, which took place from September to November, and is an official sponsor of the 2022 Simone Biles International Invitational, a gymnastics competition that will be held January 27-30 at Houston’s George R. Brown Convention Center. The Spring-based World Champions Centre, Biles’ home gym, stages the invitational.

“Mental health is just as important as physical health, but for far too long the stigma of mental health has prevented too many people from seeking help,” Biles says in a Cerebral news release. “I have my own challenges with mental health, and therapy has been very empowering for me as I try to be the best person that I can be. I believe everyone should have access to mental health resources, and Cerebral gives me the ability to personalize my mental health care experience.” Click here to read more.

Sesh Coworking's new space is 10 times as big as its previous location. Photo courtesy of Sesh

Exclusive: Houston coworking company plans to move into larger Midtown location

room to grow

A Houston startup with an inclusive approach to coworking has announced where its new location will be and plans to open in its first phase in the new year.

Sesh Coworking, which bills itself as the first female-centered and LGBTQ+-affirming coworking space, has announced its new 20,000-square-foot space at 2808 Caroline St, Suite 100 and 201. The team is all hands on deck to move over the next few weeks and formally beginning operating in the Midtown location in January 2022.

The two-story space is about ten times the size of its original location, which opened in February of 2020. Current and new tenants will move into the space's second floor in January while the first floor, the larger of the two floors, completes construction.

The new space will open in two phases. Image courtesy of Sesh

"Being able to grow our community at our beautiful original location in Montrose through the pandemic is a testament to the grit and resilience of Houstonians. We are so honored and grateful to be a part of their journey,” says Maggie Segrich, founder of Sesh Coworking. “We are excited that our new location in Midtown, near the Innovation District, will provide more Houstonians with the workspace and support they need."

The new location has hassle-free parking in a walkable part of town. In terms of layout, Sesh plans to have 25 offices, three conference rooms, four phone booths, an amphitheater, library, demo kitchen, pop-up retail shop, locker room with showers, and interactive art installations. A huge new perk of the space: 24/7 access for members.

"We plan to offer a robust calendar of programming featuring community partners such as networking events, lunch and learns, breakfast clubs, cooking classes, book clubs, business development and more," the founders tell InnovationMap.

According to Sesh, membership pricing will remain at the current rate of $199 per month, but individuals will now be able to opt into private offices starting at $789 per month for space that can accommodate teams of up to 15 people.

Sesh worked with real estate developer, The Deal Co, to customize the space in order to best meet the needs of its dynamic female and LGBTQ+ members. The new location was funded in part by a crowdfunding campaign, which raised $40,000, which represented the company’s goal. Sesh also received grant funds from the TWU Center for Women Entrepreneurs, an organization aiming to help women grow into successful business owners.

Founders Maggie Segrich (right) opened Sesh with Meredith Wheeler in 2020. Photo courtesy of Sesh

Sesh Coworking has outgrown its space in Montrose. Photo courtesy of Sesh

Houston coworking company launches crowdfund to move to bigger space

sesh we can

A Houston coworking community that's founded by women and for women has announced it's ready to move into a bigger space.

Sesh Coworking, which opened early 2020 by Meredith Wheeler and Maggie Segrich, has launched a crowdfunding campaign to fuel its move into a new space to support its growing membership. The campaign is as unique as the company is itself. Coworkers can commit to offices or desks at a 25 percent discount for six-month prepaid membership, but Sesh tapped fellow Houston companies to add in other perks for crowdfund contributors.

"We're very fortunate to have local businesses who believe in Sesh and our mission," Segrich tells InnovationMap, explaining that these businesses have contributed special products and experiences like a two-hour portrait session, chocolate boxes, jewelry and more. "Realistically, we know not everyone needs coworking, but we realize some may want to show their support and we have other opportunities."

Meredith Wheeler and Maggie Segrich founded Sesh Coworking after years of working from home and feeling the need for a community. Photo courtesy of Sesh

Investors can also snag like Sesh's Houston is Dope AF T-shirts ($35) and naming rights to their plants ($50), phone booths ($1,500) and conference rooms ($10,000). As of publication, Sesh has already raised $11,047 of their $40,000 goal.

The new coworking space is set to be in Midtown, but Sesh hasn't yet announced the specific location. The plan is to open to members at the beginning of 2022. The move will allow Sesh to offer private offices and dedicated desks, as well as other amenities members are looking for.

"These last 18 months have provided us plenty of opportunities to listen and learn from our community which means we have new amenities that we can provide them," Segrich says. "The new location will continue to provide Houstonians the spaces they need to feel inspired, energized, connected, and supported. Our goal is to make sure we provide our community with the space and tools they need to grow and succeed."

Opening right ahead of the pandemic, Sesh Coworking has cultivated an involved and collaborative community at a time when entrepreneurs and small business owners needed community more than ever. But, even outside of the pandemic, Segrich says this was always their plan.

"Sesh never set out to be like other coworking spaces," she says. "We are on a mission to create a work space that isn't just four walls and a door. We began in 2017 by building our community first through pop-ups and then with our current space in Montrose. This new space carries on that tradition and mission of putting community first."

Sesh's current space features a pinkie promise mural so unique and special to the members — but don't worry. Segrich says they are working again with Houston artist Amy Malkan to create a new and improved version of it for the new space.

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World's largest student startup competition names teams for 2025 Houston event

ready, set, pitch

The Rice Alliance for Technology and Entrepreneurship has announced the 42 student-led teams worldwide that will compete in the 25th annual Rice Business Plan Competition this spring.

The highly competitive event, known as one of the world’s largest and richest intercollegiate student startup challenges, will take place April 10–12 at Houston's The Ion. Teams in this year's competition represent 34 universities from four countries, including one team from Rice.

Graduate student-led teams from colleges or universities around the world will present their plans before more than 300 angel, venture capital, and corporate investors to compete for more than $1 million in prizes. Last year, top teams were awarded $1.5 million in investment and cash prizes.

The 2025 invitees include:

  • 3rd-i, University of Miami
  • AG3 Labs, Michigan State University
  • Arcticedge Technologies, University of Waterloo
  • Ark Health, University of Chicago
  • Automatic AI, University of Mississippi and University of New Orleans
  • Bobica Bars, Rowan University
  • Carbon Salary, Washington University in St. Louis
  • Carmine Minerals, California State University, San Bernardino
  • Celal-Mex, Monterrey Institute of Technology and Higher Education
  • CELLECT Laboratories, University of Waterloo
  • ECHO Solutions, University of Houston
  • EDUrain, University of Missouri-St. Louis
  • Eutrobac, University of California, Santa Cruz
  • FarmSmart.ai, Louisiana State University
  • Fetal Therapy Technologies, Johns Hopkins University
  • GreenLIB Materials, University of Ottawa
  • Humimic Biosystems, University of Arkansas
  • HydroHaul, Harvard University
  • Intero Biosystems, University of Michigan
  • Interplay, University of Missouri-Kansas City
  • MabLab, Harvard University
  • Microvitality, Tufts University
  • Mito Robotics, Carnegie Mellon University
  • Motmot, Michigan State University
  • Mud Rat, University of Connecticut
  • Nanoborne, University of Texas at Austin
  • NerView Surgical, McMaster University
  • NeuroFore, Washington University in St. Louis
  • Novus, Stanford University
  • OAQ, University of Toronto
  • Parthian Baattery Solutions, Columbia University
  • Pattern Materials, Rice University
  • Photon Queue, University of Illinois, Urbana-Champaign
  • re.solution, RWTH Aachen University
  • Rise Media, Yale University
  • Rivulet, University of Cambridge and Dartmouth College
  • Sabana, Carnegie Mellon University
  • SearchOwl, Case Western Reserve University
  • Six Carbons, Indiana University
  • Songscription, Stanford University
  • Watermarked.ai, University of Illinois, Urbana-Champaign
  • Xatoms, University of Toronto

This year's group joins more than 868 RBPC alums that have raised more than $6.1 billion in capital with 59 successful exits, according to the Rice Alliance.

Last year, Harvard's MesaQuantum, which was developing accurate and precise chip-scale clocks, took home the biggest sum of $335,000. While not named as a finalist, the team secured the most funding across a few prizes.

Protein Pints, a high-protein, low-sugar ice cream product from Michigan State University, won first place and the $150,000 GOOSE Capital Investment Grand Prize, as well as other prizes, bringing its total to $251,000.

Tesla recalling more than 375,000 vehicles due to power steering issue

Tesla Talk

Tesla is recalling more than 375,000 vehicles due to a power steering issue.

The recall is for certain 2023 Model 3 and Model Y vehicles operating software prior to 2023.38.4, according to the National Highway Traffic Safety Administration.

The printed circuit board for the electronic power steering assist may become overstressed, causing a loss of power steering assist when the vehicle reaches a stop and then accelerates again, the agency said.

The loss of power could required more effort to control the car by drivers, particularly at low speeds, increasing the risk of a crash.

Tesla isn't aware of any crashes, injuries, or deaths related to the condition.

The electric vehicle maker headed by Elon Musk has released a free software update to address the issue.

Letters are expected to be sent to vehicle owners on March 25. Owners may contact Tesla customer service at 1-877-798-3752 or the NHTSA at 1-888-327-4236.

Houston space tech companies land $25 million from Texas commission

Out Of This World

Two Houston aerospace companies have collectively received $25 million in grants from the Texas Space Commission.

Starlab Space picked up a $15 million grant, and Intuitive Machines gained a $10 million grant, according to a Space Commission news release.

Starlab Space says the money will help it develop the Systems Integration Lab in Webster, which will feature two components — the main lab and a software verification facility. The integration lab will aid creation of Starlab’s commercial space station.

“To ensure the success of our future space missions, we are starting with state-of-the-art testing facilities that will include the closest approximation to the flight environment as possible and allow us to verify requirements and validate the design of the Starlab space station,” Starlab CEO Tim Kopra said in a news release.

Starlab’s grant comes on top of a $217.5 million award from NASA to help eventually transition activity from the soon-to-be-retired International Space Station to new commercial destinations.

Intuitive Machines is a space exploration, infrastructure and services company. Among its projects are a lunar lander designed to land on the moon and a lunar rover designed for astronauts to travel on the moon’s surface.

The grants come from the Space Commission’s Space Exploration and Aeronautics Research Fund, which recently awarded $47.7 million to Texas companies.

Other recipients were:

  • Cedar Park-based Firefly Aerospace, which received $8.2 million
  • Brownsville-based Space Exploration Technologies (SpaceX), which received $7.5 million
  • Van Horn-based Blue Origin, which received $7 million

Gwen Griffin, chair of the commission, says the grants “will support Texas companies as we grow commercial, military, and civil aerospace activity across the state.”

State lawmakers established the commission in 2023, along with the Texas Aerospace Research & Space Economy Consortium, to bolster the state’s space industry.

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