This week's roundup of Houston innovators includes Angela Holmes of Mercury Data Science, Meredith Wheeler and Maggie Segrich of Sesh Coworking, and Shaun Zhang of the University of Houston. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from data science to cancer therapeutics — recently making headlines in Houston innovation.

Angela Holmes, CEO of Mercury Data Science

Angela Holmes is the CEO of MDS. Photo via mercuryds.com

A Houston-based AI solutions consultancy has made changes to its C-suite. Dan Watkins is passing on the CEO baton to Angela Holmes, who has served on MDS's board and as COO. As Holmes moves into the top leadership position, Watkins will transition to chief strategy officer and maintain his role on the board of directors.

"It is an exciting time to lead Mercury Data Science as we advance the development of innovative data science platforms at the intersection of biology, behavior, and AI," says Holmes in the release. "I am particularly excited about the demand for our Ergo insights platform for life sciences, allowing scientists to aggregate a vast set of biomedical data to better inform decisions around drug development priorities." Click here to read more.

Meredith Wheeler and Maggie Segrich, co-founders of Sesh Coworking

Sesh Coworking and its founders Maggie Segrich and Meredith Wheeler are on a roll. Photo courtesy of Sesh

Sesh Coworking, described as Houston’s first female-focused and LGBTQIA+ affirming coworking, has been operating its 2808 Caroline Street location's second-floor space since January, but the first floor, as of this week, is now open to membership and visitors. The new build-out brings the location to over 20,000 square feet of space.

Called The Parlor, the new space includes additional desks, common areas, a wellness room, and a retail pop-up space. Since its inception in early 2020, Sesh has overcome the pandemic-related obstacles in its path and even seen a 60 percent increase in membership with an overall 240 percent increase in sales over the past year.

“Our growth is a testament to the ever-changing landscape of Houston’s office and retail industry after the workplace dramatically changed in 2020,” says Maggie Segrich, co-founder of Sesh Coworking, in a news release. “We are ecstatic to welcome current and prospective members to our new, inclusive space.” Click here to read more.

The duo also joined the Houston Innovators Podcast to discuss Sesh's growth. Click here to listen.

Shaun Zhang, director of the Center for Nuclear Receptors and Cell Signaling at the University of Houston

A UH professor is fighting cancer with a newly created virus that targets the bad cells and leaves the good ones alone. Photo via UH.edu

A Houston researcher is developing a cancer treatment — called oncolytic virotherapy — that can kill cancer cells while being ineffective to surrounding cells and tissue. Basically, the virus targets the bad guys by "activating an antitumor immune response made of immune cells such as natural killer (NK) cells," according to a news release from the University of Houston.

However exciting this rising OV treatment seems, the early stage development is far from perfect. Shaun Zhang, director of the Center for Nuclear Receptors and Cell Signaling at the University of Houston, is hoping his work will help improve OV treatment and make it more effective.

“We have developed a novel strategy that not only can prevent NK cells from clearing the administered oncolytic virus, but also goes one step further by guiding them to attack tumor cells. We took an entirely different approach to create this oncolytic virotherapy by deleting a region of the gene which has been shown to activate the signaling pathway that enables the virus to replicate in normal cells,” Zhang says in the release. Click here to read more.

Sesh Coworking and its founders Maggie Segrich and Meredith Wheeler are on a roll. Photo courtesy of Sesh

With freshly opened inclusive coworking space, Houston founders look to continue momentum

houston innovators podcast episode 142

The origin story of Sesh Coworking is familiar to a lot of startups. Meredith Wheeler was looking for a new business opportunity — and the right network and work environment to do that — when she realized she didn't find anything out there that was what she needed. Then she thought — maybe building that was the next business opportunity she was looking for.

"I knew that I wanted each person who was introduced to our community felt unafraid," Wheeler says on this week's episode of the Houston Innovators Podcast. "It's really hard to walk into anywhere where anyone knows each other. I wanted it to feel to people that it was approachable."

Eventually relocating to Houston and syncing up with her now-business partner, Maggie Segrich, Wheeler started hosting pop-up coworking sessions. The meetups evolved into Sesh Coworking's small Montrose space that opened in early 2020.

This year, the duo got to have their dream of a bigger, inclusive coworking space actualized, and both phase one and two of the new Sesh Coworking space has opened in Midtown. Described as Houston’s first female-focused and LGBTQIA+ affirming coworking, Sesh's 2808 Caroline Street location provides its members with over 20,000 square feet of meeting, work, and event space.

With the bigger space, Wheeler and Segrich have the same mission of inclusivity and embracing diversity while growing its membership.

"At the end of the day, what our members really want is a feeling of belonging," Wheeler says. "They might need to get out of the house, and they might need to network a bit more. But what they want is a sense of belonging. Sesh provides that because we are this inclusive community."

Sesh, as the co-founders describe, is an attractive spot for creatives and business owners seeking a community and flexible environment. Membership is $199 a month for coworkers, and now, thanks to the expansion, Sesh also can provide private office space — even to coworker members.

"To jump into a private office — that's a big difference in pricing for some people, and that means that your business has to grow exponentially to get to that point," Segrich says. "So we try to make sure that all our members have access to private spaces for a few hours a day. We know that budgeting restraints are a big deal."

The Midtown location also has a similar opportunity for growing retail businesses. Just like the other members at Sesh, the shop gives retailers a smaller scale and less risky space compared to the costs associated with opening up their own brick-and-mortar shop.

With the challenges from the pandemic and the construction of the new store behind them, Segrich and Wheeler are already looking to the future for the company.

"First Houston — next, the world," Segrich says. "This location we've definitely set up to be the flagship, so there is definitely more Sesh coming whether that's in Houston, Texas, or somewhere else is yet to be determined.


Sesh's 20,000-square-foot space in Midtown is now completely open. Photo courtesy of Sesh

Photos: Houston coworking spot opens expanded first-floor space

where to work

A female-focused coworking space has officially opened the first floor of its Midtown Houston location after a months-long buildout.

Sesh Coworking, described as Houston’s first female-focused and LGBTQIA+ affirming coworking, has been operating its 2808 Caroline Street location's second-floor space since January, but the first floor, as of this week, is now open to membership and visitors. The new build-out brings the location to over 20,000 square feet of space.

Called The Parlor, the new space includes additional desks, common areas, a wellness room, and a retail pop-up space. Since its inception in early 2020, Sesh has overcome the pandemic-related obstacles in its path and even seen a 60 percent increase in membership with an overall 240 percent increase in sales over the past year.

“Our growth is a testament to the ever-changing landscape of Houston’s office and retail industry after the workplace dramatically changed in 2020,” says Maggie Segrich, co-founder of Sesh Coworking, in a news release. “We are ecstatic to welcome current and prospective members to our new, inclusive space.”

Sesh tapped real estate developer, The Deal Co, to work on the space and provide a catered experience for a diversified membership, including working mothers, the LGBTQIA+ community, and progressive Houstonians, per the news release.

The fully completed space now provides members with:

  • Hassle-free parking
  • 30 offices
  • Three conference rooms
  • Four phone booths
  • Amphitheater
  • Library
  • Studio kitchen
  • Pop-up retail shop for local small businesses
  • Locker rooms with showers
  • Interactive art installations
  • 24/7 access
  • Tech-enabled spaces
  • 15 percent at Weights + Measures, which directly connects to The Parlor

“Our vision is to provide a high-quality experience with a tight-knit community,” said Co-Founder Meredith Wheeler. “The Parlor’s open and collaborative atmosphere will help foster relationships, collaboration and creativity for our members.”

Photo courtesy of Sesh

This week's roundup of Houston innovators includes Dr. Toby Hamilton of Hamilton Health Box, Meredith Wheeler and Maggie Segrich of Sesh Coworking, and Simone Biles of Cerebral. Courtesy photos

4 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health to coworking — recently making headlines in Houston innovation.

Dr. Toby Hamilton, founder and CEO of Hamilton Health Box

Dr. Toby Hamilton is a leader in Houston's health care innovation ecosystem, and he joins the Houston Innovators Podcast to discuss his latest endeavor, which is rethinking primary and preventative care. Photo via tmc.edu

Dr. Toby Hamilton has seen Houston establish itself as a leader in health innovation, and he's been a part of that journey too. He started his career as a physician before founding Emerus Holdings, a micro-hospital system in the Houston area which later exited to private equity. He also founded a nonprofit focused on connecting hospital innovation leaders called the Healthcare Innovators Professional Society and led the Texas Medical Center's Biodesign program for two years.

Over the years, he says he's seen the potential develop for Houston to hold a significant role in health care innovation across the world — it's just going to take all hands on deck.

"As a community, if we can get behind that vision and be the place that tests, develops, and creates opportunities, Houston has the potential to be unlike anything in the world," he says on the Houston Innovators Podcast. Click here to listen and read more.

Meredith Wheeler and Maggie Segrich, founders of Sesh Coworking

Co-founders Maggie Segrich (right) opened Sesh with Meredith Wheeler in 2020. Photo courtesy of Sesh

One of Houston's coworking companies is moving on up. Sesh Coworking is moving into a new space that's 10 times as large as its original location — and it's an optimal location too, say Meredith Wheeler and Maggie Segrich, founders of Sesh Coworking.

"Being able to grow our community at our beautiful original location in Montrose through the pandemic is a testament to the grit and resilience of Houstonians. We are so honored and grateful to be a part of their journey,” says Segrich. “We are excited that our new location in Midtown, near the Innovation District, will provide more Houstonians with the workspace and support they need."

The two-story space is expected to open in two phases. Tenants will first move into the space's second floor in January while the first floor, the larger of the two floors, completes construction and is expected in March. Click here to read more.

Simone Biles, chief impact officer at Cerebral

Houston's favorite gymnast is the chief impact officer on a California-based tech company that's raised $462M. Photo via getcerebral.com

The greatest gymnast of all time has a new title to her many gymnastics accomplishments. Simone Biles recently joined mental health startup Cerebral as chief impact officer, and the company is backed by SoftBank and has a valuation of $4.8 billion.

Biles has been vocal about her passion for mental health. Cerebral was an official sponsor of Biles’ Gold Over America Tour, which took place from September to November, and is an official sponsor of the 2022 Simone Biles International Invitational, a gymnastics competition that will be held January 27-30 at Houston’s George R. Brown Convention Center. The Spring-based World Champions Centre, Biles’ home gym, stages the invitational.

“Mental health is just as important as physical health, but for far too long the stigma of mental health has prevented too many people from seeking help,” Biles says in a Cerebral news release. “I have my own challenges with mental health, and therapy has been very empowering for me as I try to be the best person that I can be. I believe everyone should have access to mental health resources, and Cerebral gives me the ability to personalize my mental health care experience.” Click here to read more.

Sesh Coworking's new space is 10 times as big as its previous location. Photo courtesy of Sesh

Exclusive: Houston coworking company plans to move into larger Midtown location

room to grow

A Houston startup with an inclusive approach to coworking has announced where its new location will be and plans to open in its first phase in the new year.

Sesh Coworking, which bills itself as the first female-centered and LGBTQ+-affirming coworking space, has announced its new 20,000-square-foot space at 2808 Caroline St, Suite 100 and 201. The team is all hands on deck to move over the next few weeks and formally beginning operating in the Midtown location in January 2022.

The two-story space is about ten times the size of its original location, which opened in February of 2020. Current and new tenants will move into the space's second floor in January while the first floor, the larger of the two floors, completes construction.

The new space will open in two phases. Image courtesy of Sesh

"Being able to grow our community at our beautiful original location in Montrose through the pandemic is a testament to the grit and resilience of Houstonians. We are so honored and grateful to be a part of their journey,” says Maggie Segrich, founder of Sesh Coworking. “We are excited that our new location in Midtown, near the Innovation District, will provide more Houstonians with the workspace and support they need."

The new location has hassle-free parking in a walkable part of town. In terms of layout, Sesh plans to have 25 offices, three conference rooms, four phone booths, an amphitheater, library, demo kitchen, pop-up retail shop, locker room with showers, and interactive art installations. A huge new perk of the space: 24/7 access for members.

"We plan to offer a robust calendar of programming featuring community partners such as networking events, lunch and learns, breakfast clubs, cooking classes, book clubs, business development and more," the founders tell InnovationMap.

According to Sesh, membership pricing will remain at the current rate of $199 per month, but individuals will now be able to opt into private offices starting at $789 per month for space that can accommodate teams of up to 15 people.

Sesh worked with real estate developer, The Deal Co, to customize the space in order to best meet the needs of its dynamic female and LGBTQ+ members. The new location was funded in part by a crowdfunding campaign, which raised $40,000, which represented the company’s goal. Sesh also received grant funds from the TWU Center for Women Entrepreneurs, an organization aiming to help women grow into successful business owners.

Founders Maggie Segrich (right) opened Sesh with Meredith Wheeler in 2020. Photo courtesy of Sesh

Sesh Coworking has outgrown its space in Montrose. Photo courtesy of Sesh

Houston coworking company launches crowdfund to move to bigger space

sesh we can

A Houston coworking community that's founded by women and for women has announced it's ready to move into a bigger space.

Sesh Coworking, which opened early 2020 by Meredith Wheeler and Maggie Segrich, has launched a crowdfunding campaign to fuel its move into a new space to support its growing membership. The campaign is as unique as the company is itself. Coworkers can commit to offices or desks at a 25 percent discount for six-month prepaid membership, but Sesh tapped fellow Houston companies to add in other perks for crowdfund contributors.

"We're very fortunate to have local businesses who believe in Sesh and our mission," Segrich tells InnovationMap, explaining that these businesses have contributed special products and experiences like a two-hour portrait session, chocolate boxes, jewelry and more. "Realistically, we know not everyone needs coworking, but we realize some may want to show their support and we have other opportunities."

Meredith Wheeler and Maggie Segrich founded Sesh Coworking after years of working from home and feeling the need for a community. Photo courtesy of Sesh

Investors can also snag like Sesh's Houston is Dope AF T-shirts ($35) and naming rights to their plants ($50), phone booths ($1,500) and conference rooms ($10,000). As of publication, Sesh has already raised $11,047 of their $40,000 goal.

The new coworking space is set to be in Midtown, but Sesh hasn't yet announced the specific location. The plan is to open to members at the beginning of 2022. The move will allow Sesh to offer private offices and dedicated desks, as well as other amenities members are looking for.

"These last 18 months have provided us plenty of opportunities to listen and learn from our community which means we have new amenities that we can provide them," Segrich says. "The new location will continue to provide Houstonians the spaces they need to feel inspired, energized, connected, and supported. Our goal is to make sure we provide our community with the space and tools they need to grow and succeed."

Opening right ahead of the pandemic, Sesh Coworking has cultivated an involved and collaborative community at a time when entrepreneurs and small business owners needed community more than ever. But, even outside of the pandemic, Segrich says this was always their plan.

"Sesh never set out to be like other coworking spaces," she says. "We are on a mission to create a work space that isn't just four walls and a door. We began in 2017 by building our community first through pop-ups and then with our current space in Montrose. This new space carries on that tradition and mission of putting community first."

Sesh's current space features a pinkie promise mural so unique and special to the members — but don't worry. Segrich says they are working again with Houston artist Amy Malkan to create a new and improved version of it for the new space.

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CultureMap Emails are Awesome

From hiring tips to AI's impact on the workforce, here's what guest columns were the most read in 2024

year in review

Editor's note: Every week, InnovationMap runs one or two guest columns written by tech entrepreneurs, public relations experts, data geniuses, and more. As Houston's innovation ecosystem gets ready for 2025, here are some of this year's top guest contributor pieces — each with pertinent information and advice for startups both at publishing and into the new year. Make sure to click through to continue reading each piece.

Is your New Year's resolution to start contributing? Email natalie@innovationmap.com to learn more.

How to avoid bad hiring decisions when it matters most, according to this Houston expert

Despite the inevitability of bad hires, recruiters equipped with proper tools and training can identify red flags and take preventive measures. Photo by Tima Miroshnichenko from Pexels

Written by Karen Leal, performance specialist with Houston-based Insperity, a provider of human resources offering a suite of scalable HR solutions available in the marketplace.

Hiring the right people for the right roles is ideal and can make an organization reach new heights. The reality is every business has made a bad hire.

Finding the wrong fit for a team or organization is not uncommon, but it is important to know what it costs the organization, which can be detrimental to company finances and its workplace culture, especially small businesses and startups where the impact is magnified.

The U.S. Department of Labor reports a bad hire can cost up to 30 percent of the employee’s wage, which would be approximately $18,000 since the average American wage is $60,000. In addition, there are soft costs of managers and leadership time during the hiring and training process, which adds up quickly. Continue reading.

How AI is changing product management and what you need to know

A product management expert shares how artificial intelligence is affecting the process for the tech and startup worlds. Photo via Getty Images

Written by Natasha Gorodetsky, founder and CEO of Product Pursuits, a Houston company that helps early stage and venture-backed startups build products and create impact.

For the past 14 months, everyone has been talking about ways artificial intelligence is changing the world, and product management is not an exception. The challenge, as with every new technology, is not only adopting it but understanding what old habits, workflows, and processes are affected by it.

Product managers — as well as startup founders leading a product function — more than any other role, face a challenge of bringing new life-changing products to market that may or may not be received well by their users. A product manager’s goal is complex — bring value, stay ahead of the competition, be innovative. Yet, the "behind the scenes" grind requires endless decision making and trade offs to inspire stakeholders to move forward and deliver.

As we dive into 2024, it is obvious that AI tools do not only transform the way we work but also help product managers create products that exceed customer expectation and drive businesses forward. Continue reading.

Houston expert shares 3 ways to stay on top of employee mental health

Companies that intentionally focus on their employees’ mental well-being will reap the benefits of a happier, healthier workforce. Photo via Getty Images

Written by Dennis Yung, executive vice president and general manager at Skanska.

Conversations surrounding mental health have come to the forefront of business and is an imperative aspect that cannot be ignored by business leaders.

Approximately 20 percent of Americans, which is 50 million people (about twice the population of Texas), are experiencing a mental illness, 15 percent of Americans had a substance use disorder in the past year and nearly 5 percent, over 12.1 million adults, reported serious thoughts of suicide (Mental Health America). Notably, certain professions, such as construction, exhibit higher suicide rates, (CDC). With these staggering numbers, the foundation of workplace safety extends beyond physical well-being to encompass psychological health.

The landscape has undergone a transformation, stemming from the pandemic, and the stigma of mental health concerns and seeking help has loosened. Recognizing that September is Suicide Prevention Month, below are three ways businesses of every size can actively support the mental well-being of their employees. Continue reading.

Houston expert shares 3 business trend predictions for 2024

Here are predictions for what current and emerging trends will further shape businesses in 2024. Photo via Getty Images

Written by Bryce Lindner, senior vice president and market executive, commercial banking in South Texas at Louisiana at Bank of America.

Last year was a dynamic year for businesses across all sectors. Artificial intelligence went from a novel technology to a more widely utilized business productivity tool. Many companies invested additional resources in sustainable business practices. And digital business solutions helped companies thrive.

Here are predictions for what current and emerging trends will further shape businesses in 2024. Continue reading.

How this Houston innovator is using his personal connection to ALS fuel his fight for a cure

Daniel Barvin has a neurodegenerative disease in his near future. He joined Houston-based Coya Therapeutics to help fight for a cure to the aggressively deadly ALS. Photo via Getty Images

Written by Daniel Barvin, vice president of operations and patient advocacy at Coya Therapeutics.

We can never predict how our lives will turn out, but then maybe some of us can. Genetic testing showed that I, like my grandfather, aunt, uncle and father before me, would most likely die of amyotrophic lateral sclerosis, more commonly known as ALS, and/or frontotemporal degeneration (FTD) in my 40s.

Being 36, it’s possible that fear could have overtaken my life, but instead I chose to fight for every chance to change not only my life, but the lives of millions who are suffering or may one day suffer from neurodegenerative disease.

ALS is a rare disease that robs one of their ability to control their muscles, leading them to lose their ability to walk, talk and eventually breathe. Eighty percent of cases are sporadic (of unknown origin) and 20 percent have known genetic causes. Continue reading.

Rice University, Houston Methodist launch new institute to revolutionize health care through AI, innovation

collaboration station

Rice University and Houston Methodist have established through a multi-year joint effort the Digital Health Institute, which aims to transform healthcare through advanced technology and the collaborative expertises of the university and hospital.

Rice’s leadership in engineering, digital health and artificial intelligence will combine with Houston Methodist’s academic medicine and research infrastructure.

“This partnership embodies Rice’s bold vision to lead at the forefront of innovation in health and responsible AI,” Rice President Reginald DesRoches says in a news release. “By combining our strengths with Houston Methodist, we are creating a transformative platform to address critical challenges in healthcare with solutions that are ethical, accessible and impactful. This initiative exemplifies our commitment to driving interdisciplinary collaboration and advancing global health for the benefit of humanity.”

Leading the initiative will be Rice’s Ashutosh Sabharwal, the Ernest Dell Butcher Professor of Engineering and professor of electrical and computer engineering, and Houston Methodist’s Dr. Khurram Nasir, the Centennial Chair in Cardiovascular Medicine, and Dr. William Zoghbi, division chief of cardiovascular prevention and wellness. Rice and Houston Methodist have worked previously with the Center for Neural Systems Restoration that opened earlier this year and the Center for Human Performance that was established in 2022.

The Digital Health Institute allows for both institutions to share data, and resources that focus on key areas like the early detection through AI algorithms for early diagnosis of cancer, infections, cardiovascular diseases and other conditions, predictive analytics that utilize real-time monitoring that can predict and prevent events such as strokes and heart failure, and the development of novel sensors, wearables and ingestibles to innovate new remote monitoring and care pathways.

The Digital Health Institute will also work to utilize more personalized medicine efforts, developments of new novel and assistive technologies, expansion of telemedicine, and proactive self-care management through AI-driven patient self-management.

“This partnership between our institutions marks a bold new chapter in driving meaningful innovation at the intersection of healthcare and technology through solutions that are both visionary and practical,” Dr. Marc Boom, president and CEO of Houston Methodist, adds. “Our long-standing relationship with Rice University has produced impactful collaborations, but this initiative is by far the most transformative endeavor in our shared commitment of leading medicine through innovation.”

Rice President Reginald DesRoches and Houston Methodist CEO Marc Boom announced the new partnership at the Ion. Photo courtesy of Rice

Elon Musk wants to turn SpaceX's Starbase site into a Texas city

mayor musk?

SpaceX is launching a new mission: making its Starbase site a new Texas city.

Billionaire Elon Musk 's company last week sent a letter to local officials requesting an election to turn what it calls Starbase — the South Texas site where SpaceX builds and launches its massive Starship rockets — into an incorporated city. Residents of the area known as Starbase submitted the petition, according to the company.

The area is on the southern tip of Texas at Boca Chica Beach, near the Mexican border. Earlier this year, Musk announced he was moving the headquarters of SpaceX and his social media company X from California to Texas.

“To continue growing the workforce necessary to rapidly develop and manufacture Starship, we need the ability to grow Starbase as a community. That is why we are requesting that Cameron County call an election to enable the incorporation of Starbase as the newest city in the Rio Grande Valley,” Kathryn Lueders, the general manager of Starbase, wrote in a letter to the county.

It's not the first time turning Starbase into its own city has been floated. Musk proposed the idea in 2021 when he wrote a social media post that simply said, “Creating the city of Starbase, Texas.”

Cameron County Judge Eddie Treviño Jr., the county’s top elected official, said despite the talks of incorporation in 2021, this was the first time a petition was officially filed.

“Our legal and elections administration will review the petition, see whether or not it complied with all of the statutory requirements and then we’ll go from there," Treviño said on Thursday.

More than 3,400 full-time SpaceX employees and contractors work at the Starbase site, according to a local impact study issued by Trevino earlier this year.

SpaceX's rapid expansion in the region has drawn pushback from some locals. Earlier this year, a group called Save RGV sued the company in July over allegations of environmental violations and dumping polluted water into the nearby bay. SpaceX said in response that a state review found no environmental risks and called the lawsuit “frivolous.”