Support Houston startups by shopping local this holiday season. Photo via Getty Images

It's giving season, and you need not look any further than Houston's startup and innovation community for some gift ideas.

This year's Houston startup gift guide includes experiences, sustainable shopping, and more.

Need some more ideas? Browse last year's roundup of Houston startup-created gift ideas, and check out the 2021, 2020 and 2019 startup gift guides as well for even more options.

For someone outdoorsy: An easy-to-book fishing trip

Mallard Bay, which won big at the Rice Business Plan Competition, expanded in Houston this year. Photo via Getty Images

After seeing success in last year's Rice Business Plan Competition, Mallard Bay, a marketplace for booking guided fishing and hunting trips, announced this year that it's moving half of its employees to Houston, InnovationMap reported. The company hopes the move will help it tap into the large corporate and convention entertainment market in Texas. You can book a trip for your family or shop gear on the startup's website.

For a wine lover: A quick cooling tool

The Cold Cork delivers 20-second beverage chilling. Photo via Facebook/Cold Cork

Perfect for someone who loves to entertain, The idea Cold Cork came from the brains of two Houstonians who love a chilled wine at the end of a long day. However, it often happens that while you're ready for wine, but the wine's not ready for you. The device, priced at $64.95, chills liquids 20 degrees in 20 seconds.

For the new mom in your life: A game-changing breastmilk service

Milkify secured a deal on Shark Tank. Photo courtesy of Milkify

As seen on Shark Tank, Houston-based Milkify provides a unique service to breastfeeding moms. The company freeze dries breast milk so that families can have the convenience of formula with the nutrition of breast milk. The startup, which won at this year's Houston Innovation Awards, secured an investment on the show and even got the nod of approval from Gwyneth Paltrow. Milkify has plans to scale, as the husband-and-wife team shared on the Houston Innovators Podcast.

For someone who loves a sweat sesh: Smell-free athletic wear

Houston-based Accel Lifestyle's innovative line of athleisure has made it into Talbots. Photo courtesy of Accel Lifestyle

For years, Houston athletic clothing brand Accel Lifestyle has been providing its customers with sporty outfits that are designed to not hold onto any stink resulting from bacteria from sweat. As of this summer, the brand is in Talbots, so you can shop in store, as well as online.

For the trendsetter: Sustainable fashion

A Houston innovator found second-hand shopping time consuming. So, she designed a better experience. Image courtesy of Trendy Seconds

Shop for one (or all) of your loved ones sustainably with Trendy Seconds, a website created by Houstonian Maria Burgos. There's likely something for everyone on your Christmas list — and no purchase can possibly considered naughty — at least when considering your carbon footprint.

For a party animal: Brews for every occasion

Bring these to your next holiday party. Photo by Emily Jaschke/InnovationMap

Two Houston companies formalized their partnership this year. Bayou City Hemp Company announced that it has purchased 8th Wonder Brewery, Distillery, and Cannabis. The acquisition deepens a relationship that dates back to 2021, when 8th Wonder and Bayou City Hemp partnered to create Wonder Water, a non-alcoholic beverage available with either CBD or Delta-8 that became the top-selling to-go product at 8th Wonder. Now, the combined company creates adult beverages by offering a full lineup of beer, spirits, and cannabis-infused drinks.

For a mother-daughter duo: A tool to enhance their relationship

Houston startup addresses mother-daughter dynamic with first app of its kindA Houston-founded company is targeting mothers and daughters with their teletherapy app. Photo courtesy of Passport Journeys

Passport Journeys, an app with a membership that helps cultivate mother-daughter relationships, can help you on your new year's resolution to heal your relationship with your mom or daughter. The intake process is $280 with monthly fees after and includes a slew of support for relationship building.

Houston-based WellWorth was selected as the winner of this year’s Houston Startup Showcase. Photo courtesy of the Ion

Houston energy startup wins Ion's annual showcase, pitch competition

1st place

The Ion hosted its annual startup pitch competition, and one company walked away with a win.

WellWorth, a financial modeling and analysis software-as-a-service company for the upstream energy sector, won the Houston Startup Showcase + Expo and secured a $5,000 prize. The startup's technology introduces a more streamlined approach to NAV modeling or corporate financial modeling for its users.

“Having worked in investment banking, I have seen firsthand how the limitations of Excel models and a lack of bespoke tools have led to inefficient workflows in upstream Oil & Gas finance," says Samra Nawaz, CEO and Co-founder of WellWorth, in a statement. "We decided to solve this problem by building a cloud-based platform that helps energy finance leaders improve decision-making around raising, managing, and deploying capital.”

Nawaz explains how impactful the opportunity to pitch has been on WellWorth, which aims to raise funding early next year accelerate customer acquisition and product development.

“By getting involved in the Ion’s innovation ecosystem, we’ve been able to not only network with many entrepreneurs and innovators in the Houston community, but also find opportunities to scale our growth,” continues Nawaz. “We’re thrilled to have brought a few more customers onboard recently, and are working closely with them to optimize our product pipeline."

The company pitched alongside the other five finalists, which included Tierra Climate, MRG Health, BeOne Sports, Trez, and Mallard Bay. Mallard Bay, a booking platform for hunting and fishing trips, secured the people's choice award, which was decided by the crowd.

“Our flagship event, Houston Startup Showcase, not only connects startups and entrepreneurs with top business leaders but also provides them an opportunity to pitch their innovations to the technology ecosystem,” says Jan Odegard, executive director of the Ion, in a news release. “We extend our congratulations to WellWorth and the company’s innovative SaaS platform for energy industry finance teams, as well as Mallard Bay, the People’s Choice winner. These companies are exemplifying the exciting new technologies being developed in Houston today.”

In addition to the pitches, several companies showcased at the event, including Nanotech, manufacturer of thermal management materials for the built environment; last year's winner Unytag, a universal toll tag that provides drivers the ability to pass through tolls anywhere in the nation; and Softeq, provides early-stage innovation, technology business consulting, and full-stack development solutions to enterprise companies and innovative startups.

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This article originally ran on EnergyCapital.

Mallard Bay, which won big at the Rice Business Plan Competition, is expanding in Houston. Photo via Getty Images

A Louisiana-born, Houston-backed outdoors activity startup is expanding into the Bayou City

growing in Hou

A Louisiana-founded hunting and fishing startup is growing its operations and expanding into Houston.

Mallard Bay, a marketplace for booking guided fishing and hunting trips, will move half of its employees to Houston and will join the Greater Houston Partnership, according to a release from the GHP. The company hopes the move will help it tap into the large corporate and convention entertainment market in Texas.

The company was founded in 2021 by a group of Louisiana State University students after noticing a gap in the outdoor travel space. Last year, founders Logan Meaux, Joel Moreau, Wyatt Mallett and Tam Nguyen entered in the Rice Business Plan Competition and won the fourth-most in investments and prizes, totaling $218,000.

“Entering the Rice Business Plan Competition helped close out our $1.8 million seed round last September,” Meaux, co-founder and CEO of Mallard Bay, says in a statement. “Not only did it help us raise money, but the recognition and the contacts we made were instrumental in growing the business and sparked the idea to expand to Houston. Prior to the competition, we were unaware of all that the Houston startup ecosystem had to offer, but quickly realized the value of having a network here in Houston.”

That same year the company also acquired Texas-based marketing firm, Bourbon Media. The company also recently launched GuideTech, which provides guides and charter services with tools like calendar management and payment solutions for back-office use, the Baton Rouge Business Report reported earlier this year.

According to the GHP, Mallard Bay now works with more than 300 outfitters, ranchers and charter captains. The company has seen more than 1,000 percent YOY growth over the last five months.

Houston-based technology services development company Softeq Venture Studio is a major investor in Mallard Bay. According to a statement from Billy Grandy, chief innovation officer at Softeq and Managing Partner of the Softeq Venture Fund, the company began working with Mallard Bay in 2022.

"The company has garnered significant interest since participating in The Softeq Venture Studio, our hands-on startup accelerator program and we are eager to see where this next chapter takes them," Grandy added in the statement.

Softeq announced its latest cohort for its accelerator program in May.

Houston is also home to outdoors and sporting equipment marketplace Everest. Founder and CEO Bill Voss spoke on the Houston Innovators Podcast about how Everest aims to disrupt the marketplace with its seller-friendly platform.
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Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.

5 incubators and accelerators fueling the growth of Houston startups

meet the finalists

Houston is home to numerous accelerators and incubators that support founders in pushing their innovative startups and technologies forward.

As part of our 2025 Houston Innovation Awards, the new Incubator/Accelerator of the Year category honors a local incubator or accelerator that is championing and fueling the growth of Houston startups.

Five incubators and accelerators have been named finalists for the 2025 award. They support startups ranging from hard-tech companies to digital health startups.

Read more about these organizations below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled.

Get your tickets now on sale for this exclusive event celebrating Houston Innovation.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its second Houston cohort this summer.

This year, the incubator grew to include its largest number of concurrent supported fellows, with 88 companies currently being supported nationally. In total, Activate has supported 296 fellows who have created 236 companies. Those companies have raised over $4 billion in follow-on funding, according to Activate. In Houston, it has supported several Innovation Awards finalists, including Solidec, Bairitone Health and Deep Anchor Solutions. It is led locally by Houston Managing Director Jeremy Pitts.

EnergyTech Nexus

Cleantech startup hub EnergyTech Nexus' mission is to accelerate the energy transition by connecting founders, investors and industrial stakeholders and helping to develop transformative companies, known as "thunderlizards."

The hub was founded in 2023 by CEO Jason Ethier, Juliana Garaizar and Nada Ahmed. It has supported startups including Capwell Services, Resollant, Syzygy Plasmonics, Hertha Metals, EarthEn Energy and Solidec—many of which are current or past Innovation Awards finalists. This year Energy Tech Nexus launched its COPILOT Accelerator, powered by Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory (NREL). COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. Energy Tech Nexus also launched its Liftoff fundraising program, its Investor Program, and a "strategic ecosystem partnership" with Greentown Labs.

Greentown Labs

Climatetech incubator Greentown Labs offers its community resources and a network to climate and energy innovation startups looking to grow. The collaborative community offers members state-of-the-art prototyping labs, business resources and access to investors and corporate partners. The co-located incubator was first launched in Boston in 2011 before opening in Houston in 2021.

Greentown has seen major changes and activity this year. In February, Greentown announced Georgina Campbell Flatter as its new CEO, along with a new Board of Directors. In July, it announced Lawson Gow as its Head of Houston, a "dedicated role to champion the success of Greentown Houston’s startups and lead Greentown’s next chapter of impact in the region," according to Greentown. It has since announced numerous new partnerships, including those with Energy Tech Nexus, Los Angeles-based software development firm Nominal, to launch the new Industrial Center of Excellence; and Houston-based Shoreless, to launch an AI lab onsite. Greentown Houston has supported 175 startups since its launch in 2021, with 45 joining in the last two years. Those startups include the likes of Hertha Metals, RepAir Carbon, Solidec, Eclipse Energy (formerly GoldH2) and many others.

Healthtech Accelerator (TMCi)

The Healthtech Accelerator, formerly TMCx, focuses on clinical partnerships to improve healthcare delivery and outcomes. Emerging digital health and medical device startups that join the accelerator are connected with a network of TMC hospitals and seasoned advisors that will prepare them for clinical validation, funding and deployment.

The Healthtech Accelerator is part of Texas Medical Center Innovation, which also offers the TMCi Accelerator for Cancer Therapeutics. The Healthtech Accelerator named its 19th, and latest, cohort of 11 companies last month.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with 24,000-plus members spanning 69 countries, making it one of the world’s largest communities for accelerating entrepreneurial solutions toward the United Nations' Sustainable Development Goals (SDGs).

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.



Rice University launches  engineering-led brain science and health institute

brain research

Rice University has announced the creation of a new interdisciplinary center known as the Rice Brain Institute (RBI).

The new hub will aim to use engineering, natural sciences and social sciences to research the brain and reduce the burden of neurodegenerative, neurodevelopmental and mental health disorders.

“The Rice Brain Institute reflects Rice’s strength in collaboration without boundaries,” Rachel Kimbro, dean of the School of Social Sciences, said in a news release. “Our researchers are not only advancing fundamental science but they’re also ensuring that knowledge reaches society in ways that promote human flourishing.”

RBI researchers will work in thematic clusters focusing on neurodegeneration, mental health, brain injury and neurodevelopment. The clusters will work toward goals such as significantly improving key brain health outcomes, reducing mortality and mental health disorders and improving quality of life for patients living with brain injuries and neurodevelopmental disorders, according to Rice.

The institute will focus on “engineering-driven innovation,” rather than traditional neuroscience, to design tools that can measure, model and modulate brain activity based around Rice’s expertise in soft robotics, neuroimaging, data science and artificial intelligence—making it unique among peer organizations, according to Rice.

Additionally, RBI will be structured around three collaborative Rice “pillars”:

  • The Neuroengineering Initiative, launched in 2018, brings together neuroscience, engineering, and related fields experts
  • The Neuroscience Initiative, a new initiative that brings together cell biologists, neurobiologists, biochemists, chemists and physicists to explore fundamental mechanisms of the brain and nervous system
  • The Brain and Society Initiative, also a new initiative, considers brain research within the broader social and policy landscape

Rice’s Neuroengineering Initiative has already garnered more than $78 million in research funding, according to Rice, and has established major partnerships, like the Rice-Houston Methodist Center for Neural Systems Restoration.

“Rice is uniquely equipped to bridge and connect scientific understanding of the brain and behavior sciences with the technologies and policies that shape our world,” Amy Dittmar, the Howard R. Hughes Provost and executive vice president for academic affairs, added in the news release. “By uniting faculty in neuroengineering, neuroscience and psychological sciences, this interdisciplinary hub embodies the kind of bold, nimble collaboration that allows Rice to turn discovery into societal impact to save lives and enhance human flourishing.”

The formation of the RBI coincides with recent support of the Dementia Prevention Research Institute of Texas (DPRIT), which landed voter approval earlier this week and aims to make Texas the center for dementia research via brain-health tech. According to the World Economic Forum, brain disorders and mental health disorders cost the global economy an estimated $5 trillion per year and could be as high as $16 trillion by 2030.

“Few areas of research have as direct and profound an impact on human well-being as brain health,” Rice President Reginald DesRoches added in the news release. “As rates of Alzheimer’s, dementia and other neurological diseases rise in our country and around the world, universities have a responsibility to lead the discovery of solutions that preserve memory, movement and quality of life. We all know someone who has been affected by a brain-related health issue, so this research is personal to all of us.”