Overheard: Why these 3 startups relocated to Houston

eavesdropping at the houston innovation awards gala

Here's why three New to Hou finalists from the Houston Innovation Awards have committed to Houston. Photo via Getty Images

Houston is attracting more and more businesses big and small, old and new. So much that it seemed worthy of an award for the Houston Innovation Awards Gala.

The awards event, which is on November 9 and hosted by InnovationMap and Houston Exponential at the Ion, is honoring five finalists selected by judges — and naming one winner — who have recently relocated or significantly expanded to Houston.

Here's why three of these New to Hou finalists have committed to Houston.

"The move to the Houston area allowed us to be much closer to our strategic partners, customers and suppliers. We are also impressed by the vast talent pool in the area. Houston has a highly skilled workforce with diverse experiences, particularly in oil and gas, petrochemicals, and a broad range of technical areas."

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— Jay Manouchehri, CEO of Fluence Analytics, which relocated from Louisiana to Stafford last year, just outside of Houston. "We have been able to engage very actively with many customers since the move and also have developed valuable supplier relationships."

"In 2019, Chevron and EIC (both Houston based) became investors and we already had a lot of US clients, so we wanted to create a Houston footprint."

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— John van Pol, co-founder and CEO of INGU, which opened its new Houston office in 2021. Van Pol adds that the pandemic delayed their expansion initially.

"Houston has a quickly-growing biotechnology sector and already has existing oil and gas talent, making it an ideal place to find the people we need to grow our business."

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— Zimri T. Hinshaw, founder and CEO of BUCHA BIO, which relocated to Houston from New York in January 2022. "Our most prominent investor is Houston-based New Climate Ventures," he adds.

This week's roundup of Houston innovators includes Anouk van Pol of INGU Solutions, Eric Tait of Urban Capital Network, and Chris Howard of Softeq. Courtesy photos

3 Houston innovators to know this week

Who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from venture capital to energy — recently making headlines in Houston innovation.

Anouk van Pol, co-founder and COO of INGU Solutions

INGU Solutions has established its U.S. office in Houston — and is ready to tap into the city's energy industry with its revolutionary pipeline inspection-as-a-service model. Photo via LinkedIn

After generating some fresh funds from U.S. investors in 2019, Canadian pipeline services company INGU Solutions decided it was time to open a new office somewhere in the country. The startup led by a father-daughter team chose Houston and opened up an office just ahead of the first wave of the COVID-19 pandemic.

“The idea was to be closer to our customers,” Anouk van Pol, COO, tells InnovationMap. “Houston is the oil and gas hub, and just being able to be in [our clients'] offices and be there in person it just helps. I hope at one point COVID passes and that we can make use out of it a bit more.

Despite the challenges of the pandemic, INGU, which uses data analytics and a small sensor to inspect pipes within the energy and water industries, grew 60 percent over the past two years. Click here to read more.

Eric Tait, co-founder at Urban Capital Network

Urban Capital Network have launched a fund-of-funds to allow investors to tap into later-stage startups at a much lower barrier of entry. Photo via urbancapitalnetwork.com

With its new fund of funds, Houston-based Urban Capital Network is allowing its members the chance to invest in venture funds at a much lower barrier of entry. The Horizon Fund II will deploy capital in up to five funds — each with 15 to 30 portfolio companies.

Eric Tait, co-founder at UCN, says they are looking for variety in the funds they invest in and are targeting top-tier, and highly rated VC firms all over the country that UCN's leadership has connections with.

“We’re relatively agnostic in terms of industry,” Tait says. “We do try to have a portfolio allocation that will create a return threshold that is varied.” Click here to read more.

Chris Howard, CEO and founder of Softeq

A Houston software company has announced its new venture fund. Photo courtesy of Softeq

Last week, Houston-based Softeq Development Corporation, a global full-stack development company, launched The Softeq Venture Fund, a $40 million venture fund to invest in seed and series A startup rounds. According to a news release, more than half the fund will be deployed to power the Softeq Venture Studio, Softeq's recently launched accelerator program.

“For generations, the state of Texas has been home to world-renowned tech companies who have greatly contributed to our regional success. As a local entrepreneur, advisor, and angel investor, it’s been my dream for many years to create a venture fund benefiting startups," says Christopher A. Howard, founder and CEO of Softeq, in the release. "I am proud to increase our support of the state’s early-stage tech community. Our investment fund is designed to attract tech visionaries from both inside and outside the state and grow innovative concepts in Houston." Click here to read more.

INGU Solutions has established its U.S. office in Houston — and is ready to tap into the city's energy industry with its revolutionary pipeline inspection-as-a-service model. Photo via ingu.com

Innovative Canadian company taps into Houston market to better serve energy customers

in the pipeline

On average, oil and gas pipelines are inspected every five years, which, considering pipelines in the United States are more than 60 years old, just isn't cutting it. Operators face costly and damaging leaks on cracks and incidences that are totally avoidable with more regular inspection. The issue is inspection isn't an easy process — unless INGU Solutions is involved.

The Alberta, Canada-based company has created a hardware component — called a Piper — that's about the size of a baseball. The device can be run through pipes of any size to inspect and detect internal issues. INGU has an inspection-as-a-service model so that whatever data is collected by the Pipers is analyzed and provided to clients without any more steps from them.

The idea for the device came to John van Pol, founder and CEO, who has a background in nuclear physics and founded the company in 2015. Now, he runs the company with his daughter, Anouk van Pol, who started as an analyst and working in the field for INGU and now serves the company as co-founder and COO.

The Piper is smaller than a baseball and can flow through any sized pipe used in the oil and gas industry. Photo via ingu.com

In 2017, INGU was selected to be a part of Chevron's inaugural Catalyst Program cohort and Chevron Technology Ventures — along with two other U.S. investors — contributed to the company's series A round in 2019. This led to INGU establishing its U.S. operations in Houston in order to grow their American team and to be closer to customers. Then, the pandemic hit.

“The idea was to be closer to our customers,” Anouk tells InnovationMap. “Houston is the oil and gas hub, and just being able to be in [our clients'] offices and be there in person it just helps. I hope at one point COVID passes and that we can make use out of it a bit more.

"The other thing is you open up your market on the hiring side," she says, adding that the company has two U.S. employees now.

INGU first had an office in The Cannon, but now operates locally at The Ion in the Common Desk coworking space with an office suite to support its local team. In 2019, the company was named to Plug and Play's inaugural Houston cohort and as a most-promising business by Rice Alliance at OTC.

Anouk, who was selected for Forbes 30 Under 30 in energy in 2020, and her father both split their time between Houston and Alberta, usually alternating so that the van Pols have a presence in each office at all times, but both are currently in town for the 34th annual Pipeline Pigging and Integrity Management conference, or PPIM. It's the OTC for the pipeline industry, Anouk says.

Ahead of the conference and despite the challenges the pandemic has posed for INGU, Anouk says the company has seen significant growth over the past two years.

"We grew 60 percent last year," she says. "which is pretty good for what's been happening over the past two years."

From a hardware perspective, the pandemic's impact has been relatively small. The Pipers are designed with off-the-shelf materials, which INGU stocked up on — avoiding any supply chain shortages. Additionally, INGU can send the devices to pipeline operators, who can deploy them while the devices send the collected data directly to INGU.

Anouk van Pol is the company's COO. Photo via LinkedIn

The company, which anticipates a secondary series A round this year in addition to tripling its annual revenue, has an environmental, social, and governance, or ESG, component to its business. While half of INGU's clients are in the energy industry and Pipers contribute to reducing waste within oilfield operations, the other half of customers are within the water industry. Water infrastructure is 100 years old, and Anouk says about 6 billion gallons of water are wasted each day.

"That's 40 percent of all water, and because so much water is lost, you need more power and energy," Anouk says. "Where we see oil and gas is aimed at prevention in well condition, etc., the water market is doing a lot of leak protection."

In both industries, Pipers are preventing waste and allowing companies to make positive moves in their ESG plans.

INGU has clients all over the world and servicing these various types of pipes and businesses is growing INGU's database, which better benefits their inspection-as-a-service capabilities.

"The more we grow, the more we can and will learn, and then go in this self-fulfilling cycle," Anouk says.

Startups from across the world pitched at the Rice Alliance Startup Roundup at the Offshore Technology Conference. Getty Images

Rice Alliance names the 10 most promising startups at Houston's Offshore Technology Conference

Best of the rest

Over 50 different startups from across the globe gathered at the Offshore Technology Conference for the fifth annual Rice Alliance Startup Roundup event. The full day of speed pitching and presentations, hosted by Rice Alliance Managing Director Brad Burke, took place at NRG Arena on Monday, May 6.

After interacting with all the various startups, the Rice Alliance's panel of experts voted on the 10 most promising startups. Half of the companies that were recognized are based in Houston — and even more have an office or some sort of operations in town. Here's which technologies the offshore oil and gas industry has its eye on.

Oliasoft AS

Oliasoft provides solutions for digitizing well planning operations. Photo via oliasoft.com

Oslo, Norway-based Oliasoft kicked off the presentations at OTC and walked away with an award 2.5 hours later. The cloud-based technology allows for enhanced well planning, casing and other drilling engineering processes.

Syzygy Plasmonics

Syzygy Plasmonics is a chemicals company in Houston lead by Trevor Best. Best presented his company's hydrogen as a fuel alternative technology. According to best, Syzegy's technology is a lower cost solution to gasoline that doesn't put out any chemical waste.

Toku Systems Inc.

Canadian IIoT company, Toku Systems Inc., has a inexpensive monitoring device. Photo via tokuindustry.com

When it comes to monitoring operations, it can be pricey and inaccurate. Edmonton, Alberta-based Toku Systems Inc. has designed a solution. Toku's device is durable and uses IIoT technology to allow for oil and gas companies to monitor their operations remotely.

Ingu Solutions

Ingu Solutions' Pipers technology might look small — but it's able to save a whole lot of cash for oil companies and prevent leaks. Photo via ingu.co

Another Canadian company, Ingu Solutions from Calgary, Alberta, took home an award from Rice. The company's pipeline detection technology can access pipes' conditions and prevent leaks and damage from causing major, costly events. Ingu's Pipers technology works off a subscription model, so clients have access to support and supplies with their monthly fees to the company.

LaserStream

LaserStream uses its imaging technology to track the wear and tear on pipes. Photo via laserstreamlp.com

Humble-based LaserStream provides laser-based scans of pipeline. The technology can evaluate damage and corrosion as well as calculate measurements of various equipment. The company has inspected over 350,000 feet of materials , including tubing, casing, drilling risers, production risers, and more, according to the website.

Ondaka

Ondaka's technology allows you to visualize your infrastructure before you act. Photo via ondaka.com

Ondaka isn't your typical Bay Area startup. The company uses an alphabet soup of buzzword technologies — IoT, AI, VR — and allows oil and gas companies to really visualize their infrastructure. The Palo Alto-based startup is a StartX company and a member at Station Houston for its local office.

Dark Vision Technologies Inc.

Canada-based Dark Vision has created a tool that can take ultrasound images of wells. Photo via darkvisiontech.com

North Vancouver, British Columbia-based Dark Vision has spent years developing its ultrasound technology that can get a 360-degree view of oil wells. According to the website, Dark Vision can find a number of downhole issues, such as tubing defects, casing corrosion, obstructions, and more.

Cemvita Factory

The Karimi siblings have created a way to synthetically convert CO2 into glucose, and they are targeting the energy and aerospace industries for their technology. Courtesy of Cemvita Factory

Houston-based Cemvita Factory didn't present its CO2-to-glucose conversion technology at the roundup, but the company's presence earlier in the day was enough for the judges. Co-founder Moji Karimi tells InnovationMap in a previous story about how the technology has many applications in oil and gas, but also in space operations,

Lift Etc.

Even though Lift ETC didn't present in the roundup, the Houston-based company walked away with an award for its artificial lift technology that is more efficient and cheaper for companies to use. According to the website, Lift ETC has a technology that's proven to lower the surface compressor requirements up to 75 percent and increase production.

SensorField

Houston-based SensorField didn't present, but still walked away with recognition from Rice. Photo via sensorfield.com

When it comes to using IoT for remote oilfield site monitoring, Houston-based SensorField is ahead of the curve. The company's device — so small it can fit in the palm of your hand — is powerful enough to provide complete monitoring capabilities from fluid level and pressure to rotating machinery health and location security, according to the website.

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

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