6 female-founded startups shaping the Houston innovation ecosystem

meet the finalists

Meagan Pitcher, CEO of Houston-based Bairitone Health. Photo courtesy of LinkedIn

Female-founded businesses reached a new milestone last year. According to payroll company Gusto, female founders launched 49 percent of new businesses in 2024, reaching near parity with male-founded businesses for the first time.

And though they still face challenges, with access to VC funding at the top of the list, those women-led companies are driving major impact in the startup and innovation ecosystem.

The fifth-annual Houston Innovation Awards will honor six women-led startups that are shaping Houston innovation in our Female-founded Businesses category, presented by Houston Powder Coaters.

The finalists for the 2025 award, selected by our esteemed panel of judges, range from a company developing natural carbon-free fuel to another launching at-home sleep apnea technology.

Read more about these innovative startups and the visionary female founders behind them below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled at our live awards ceremony.

Tickets are now on sale for this exclusive event celebrating all things Houston innovation.

Anning Corporation

Clean energy company Anning Corporation is working to develop geologic hydrogen, a natural carbon-free fuel, using its proprietary stimulation approaches and advanced exploration modeling. The company said that geologic hydrogen has the potential to be the lowest-cost source of reliable baseload electricity in the U.S.

The company was founded by CEO Sophie Broun in 2024 and is a member of Greentown Labs. Last month, it also announced that it was chosen to participate in Breakthrough Energy’s prestigious Fellows Program. Anning raised a pre-seed round this year and is currently raising a $6 million seed round.

Bairitone Health

Bairitone Health is bringing anatomy imaging for sleep apnea to the home environment. The company's platform maps users' anatomy during natural sleep using a facial patch to determine the root cause of airway obstruction. It then offers effective therapies for each patient. The system is currently in the research and development phase and is being used in clinical trials and studies.

The company was founded in 2022 in the Texas Medical Center's Biodesign program by CEO Meagan Pitcher, CTO Onur Kilic and chief medical officer Britt Cross. It was a member of Activate Houston's inaugural cohort and has participated in numerous accelerators and incubators. It raised a pre-seed round last year of $435,000.

Brain Haven

Founded at the University of Houston, Brain Haven is developing neuroscience-based, clinically validated protocols that use sensory stimulation through smell and sound to offer a natural and non-invasive way to activate the brain and preserve neuroplasticity. The company aims to deliver an accessible and affordable way for the aging population to preserve memory, delay cognitive decline and improve quality of life.

The company was co-founded by Gail Aflalo, a graduate student in the University of Houston College of Optometry, and Jokūbas Žiburkus, an associate professor in the department of biology and biochemistry at UH. It was selected to participate in the 2024 Innov8 Cohort, where it won the cohort's Startup Pitch Day, and was included in Class 13 of UH RED Labs. Brain Haven was awarded $70,000 in seed funding from UH in June 2025 to support a year-long research initiative in adults aged 50 and above.

FlowCare

Sugar Land-based FlowCare is developing a period health platform that integrates smart dispensers, education and healthcare into one system to make free, high-quality organic period products more accessible.

The company was founded by CEO Tanu Jain, a registered nurse and product management executive, in 2024. It participated in the TiE Women Program and the Houston Community College Business Plan Competition, placing in the top five in both pitch competitions.

March Biosciences

Houston cell therapy company March Biosciences aims to treat unaddressed challenging cancers, with its MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma, currently in Phase 2 clinical trials.

The company was founded in 2021 by CEO Sarah Hein, Max Mamonkin and Malcolm Brenner and was born out of the TMC Accelerator for Cancer Therapeutics. The company completed a $29.6 million series A last year and also raised a $4.2 million seed round.

TrialClinIQ

Houston-based TrialClinIQ is an AI-powered clinical trial recruitment platform that helps identify, qualify and enroll eligible patients in appropriate trials faster and more accurately.

The company was founded in 2025 by CEO Jontel Pierce and Janette Obi.

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.

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Female-founded companies in the U.S. raised $38.8 billion, up 27 percent from the previous year, but deal count dropped, according to VC data from PitchBook. Photo via Getty Images.

Texas female-founded companies raised more than $1 billion in 2024, VC data shows

by the numbers

Female-founded companies in Dallas-Fort Worth may rack up more funding deals and more money than those in Houston. However, Bayou City beats DFW in one key category — but just barely.

Data from PitchBook shows that in the past 16 years, female-founded companies in DFW collected $2.7 billion across 488 deals. By comparison, female-founded companies in the Houston area picked up $1.9 billion in VC through 343 deals.

Yet if you do a little math, you find that Houston ekes out an edge over DFW in per-deal values. During the period covered by the PitchBook data, the value of each of the DFW deals averaged $5.53 million. But at $5,54 million, Houston was just $6,572 ahead of DFW for average deal value.

Not surprisingly, the Austin area clobbered Houston and DFW.

During the period covered by the PitchBook data, female-founded companies in the Austin area hauled in $7.5 billion across 1,114 deals. The average value of an Austin deal: more than $6.7 million.

Historically, funding for female-established companies has lagged behind funding for male-established companies. In 2024, female-founded companies accounted for about one-fourth of all VC deals in the U.S., according to PitchBook.

PitchBook noted that in 2024, female-founded companies raised $38.8 billion, up 27 percent from the previous year, but deal count dropped 13.1 percent, meaning more VC for fewer startups. In Texas, female-founded companies brought in $1.3 billion last year via 151 deals. The total raised is the same as 2023, when Texas female founders got $1.3 billion in capital across 190 deals.

“The VC industry is still trying to find solid footing after its peak in 2021. While some progress was made for female founders in 2024, particularly in exit activity, female founders and investors still face an uphill climb,” says Annemarie Donegan, senior research analyst at PitchBook.

Stephanie Tsuru joins this week's Houston Innovators Podcast to share her growth plans for 2023. Photo via LinkedIn

Houston founder shares expansion plans for female-focused coworking

houston innovators podcast episode 169

Stephanie Tsuru didn't know much about coworking when she decided to jump headfirst into creating SheSpace.

On this week's episode of the Houston Innovators Podcast, Tsuru, founder and CEO of SheSpace, explains that she saw an need for a place for women — entrepreneurs, independent contractors, remote workers, etc. — to congregate and collaborate. So, she filled that need.

"The idea wasn't about coworking — it was a place to bring women together so that they didn't have to sit by themselves in a coffee shop," she says on the show.

Tsuru opened the membership-based space with her daughter-in-law Katie in November of 2020, and has already expanded to support its growing membership. In August 2021, SheSpace added an additional 1,500 square feet. Now, the company has 250 women in its network, whether they rent a private office, hotdesk, or just attend for events — something Tsuru says was created based on interest from potential members.

"We had so many people who wanted to be a part of the community — so we started a social networking group," she says.

SheSpace was designed very intentionally, Tsuru explains on the podcast. Everything from the colors on the walls to the parking and surrounding retail access was intentional.

"Women have a lot of stuff on their plate," she says, explaining how SheSpace has a gas station, a grocery store, a nail salon, and more within the same retail property. "We don't get our stuff done in an office complex."

SheSpace has a busy year ahead. While the Heights-area location will be SheSpace's flagship and where programming will continue to be held, Tsuru says she has plans to open a satellite location to accommodate a growing membership and Houston's sprawl.

"We are looking at satellite areas for more offices, workspace, and meeting rooms," she says. "We'll make a decision and have a location this year."

She shares more about what she's accomplished with SheSpace in its first two years — as well as what's next on the podcast. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


In observance of Women’s Entrepreneurship Day on November 19, here are four key considerations for women who want to start their own businesses. Photo via Getty Images

Houston expert: 4 things female founders should know before starting a business

guest column

Almost four years ago my business partner and I started Volante Integrated Planning, a Houston-based office of Northwestern Mutual focused on comprehensive financial planning. I always aspired to run a business; however, I knew there were many factors to consider before making that leap.

According to the 2022 Northwestern Mutual Great Realization survey, 24 percent of respondents say they want to start a new business in the next two years. While starting your own business sounds appealing, leaving your current job and becoming an entrepreneur can be a difficult transition — and it’s no secret that women have to approach our career paths differently than men.

As I recognize there is no one-size-fits-all approach to starting and managing your own business, I wanted to share a few valuable lessons and key takeaways that I learned from my own experience:

1. Seek advice and counsel

When it comes to starting your own business, it’s important to go through the proper financial and legal steps. In order to do this, there are three people you should consider developing a relationship with. The first is a financial planner who can assist you in growing your business by creating a budget and finding ways to leverage your current assets to set you up for long-term success. The second is a Certified Public Accountant who has experience in your industry to help you navigate the unique intricacies of being a business owner. Lastly, an attorney who can help you draw up the necessary documents and think through what needs to be included to protect you and your family.

2. Build your team

You will always need a support system and business team to lean on no matter how much experience you have in your industry or in running a business. I knew early on that I wanted to partner with someone to make it more fun and add higher value to our clients. Before launching our business partnership, we went through varying business cycles together to ensure we would mesh well, from a value standpoint, both financially and personally. This business “courtship” is critical to ensure you build the kind of trust needed. It is also important to develop the culture and values you want for your business first and choose partners or team members that align with those values.

3. Don’t be afraid to be authentic

People are drawn to authenticity rather than if you try to fit into a box, which is why it’s important to stay true to yourself in all aspects of your business. By being your true, authentic self, you can put a plan in place to start a business that is a reflection of your values and morals. If being a working mom is a part of your identity, don’t be afraid to make that known to the team. There is nothing that says you have to start a business a certain way, so make it yours and own it.

4. Give yourself grace

As women, we have a tendency to want to do it all, but it’s important to give yourself grace and be intentional with how you prioritize your time. There are certain life factors and considerations that ultimately influence how women prepare for their financial futures, especially when it comes to running a business. If starting or managing your business is the priority at the time, it’s OK to let your social life or fitness routine, for example, take the back burner for a period of time.

Being a female business owner has its challenges, but it is also extremely rewarding. If you’re considering starting your own business, it’s important to remember to stay true to yourself and do your due diligence to prepare for whatever unique challenges may be thrown your way.

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Jennifer Steil is a Houston-based Northwestern Mutual wealth management adviser.

Sesh Coworking's new space is 10 times as big as its previous location. Photo courtesy of Sesh

Exclusive: Houston coworking company plans to move into larger Midtown location

room to grow

A Houston startup with an inclusive approach to coworking has announced where its new location will be and plans to open in its first phase in the new year.

Sesh Coworking, which bills itself as the first female-centered and LGBTQ+-affirming coworking space, has announced its new 20,000-square-foot space at 2808 Caroline St, Suite 100 and 201. The team is all hands on deck to move over the next few weeks and formally beginning operating in the Midtown location in January 2022.

The two-story space is about ten times the size of its original location, which opened in February of 2020. Current and new tenants will move into the space's second floor in January while the first floor, the larger of the two floors, completes construction.

The new space will open in two phases. Image courtesy of Sesh

"Being able to grow our community at our beautiful original location in Montrose through the pandemic is a testament to the grit and resilience of Houstonians. We are so honored and grateful to be a part of their journey,” says Maggie Segrich, founder of Sesh Coworking. “We are excited that our new location in Midtown, near the Innovation District, will provide more Houstonians with the workspace and support they need."

The new location has hassle-free parking in a walkable part of town. In terms of layout, Sesh plans to have 25 offices, three conference rooms, four phone booths, an amphitheater, library, demo kitchen, pop-up retail shop, locker room with showers, and interactive art installations. A huge new perk of the space: 24/7 access for members.

"We plan to offer a robust calendar of programming featuring community partners such as networking events, lunch and learns, breakfast clubs, cooking classes, book clubs, business development and more," the founders tell InnovationMap.

According to Sesh, membership pricing will remain at the current rate of $199 per month, but individuals will now be able to opt into private offices starting at $789 per month for space that can accommodate teams of up to 15 people.

Sesh worked with real estate developer, The Deal Co, to customize the space in order to best meet the needs of its dynamic female and LGBTQ+ members. The new location was funded in part by a crowdfunding campaign, which raised $40,000, which represented the company’s goal. Sesh also received grant funds from the TWU Center for Women Entrepreneurs, an organization aiming to help women grow into successful business owners.

Founders Maggie Segrich (right) opened Sesh with Meredith Wheeler in 2020. Photo courtesy of Sesh

The five finalists in the Female-Founded Business category for the inaugural InnovationMap Awards share the challenges they overcame as female founders. Photos courtesy

Houston founders share the challenges they've had to overcome as women in tech

innovationmap awards

Even in 2021, women face discrimination in the workplace — whether it's running their own businesses or climbing the corporate ladder.

The five female finalists of the Female-Founded Business category for the InnovationMap Awards presented by Techwave were asked to share their challenges overcame as female founders. Here's what they had to say. Click here to register for the livestream.

Raising capital

Carolyn Rodz, founder of Hello Alice, says raising capital was her biggest challenge.

"We overcame it through insane networking and persistence," she continues. "Each round got easier as we proved that we knew how to grow this business and build a fiercely loyal owner community.

Katharine Forth, co-founder of Zibrio, agrees that raising early funding was her biggest challenge.

"To overcome it, I was very creative with the limited funds to generate the progress we created until we reached a threshold that was more comfortable for investors," she explains.

Being the only woman in the room

"This is a hurdle in and of itself, but it brings lots of other little behavioral hurdles too," says Kim Raath, CEO and co-founder of Topl. "Because men and women are socialized so differently, women often have to adapt to or accommodate for male-pattern behaviors."

Raath continues, saying how men tend to up-sell what they are doing, while women undersell. Additionally, she says, men are more likely to make statements while women suggest their ideas.

"It takes a lot of courage to fight for yourself and your ideas in a room full of men," Raath says. "You can't expect others to do it for you. Even further, those of us that are in the room have a duty to speak up, not just for our own sake, but for other voices that are still excluded. Being a woman in the tech space means learning how to accommodate, navigate, and hold your ground."

Being treated equally

For Samantha Snabes, co-founder of re:3D, her biggest challenge was being treated the same as her male co-founder.

"I've learned that I need to be more confident and to be proud of the differences in my leadership or communication style," she explains.

Being mistaken for the secretary

Shoshi Kaganovsky, founder of RingOn, says electronics is a very male dominated arena.

"Every time I approach a man — whether to interview him for a job or to partner up on another level — they think I'm the CEO's secretary," she says.

"When male investors talk to me they often times think I don't understand what I'm doing or that they need to dumb it down for me," continues Kaganovsky, who speaks five languages and has six degrees. "Second conversations are completely different usually."

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Aegis Aerospace appoints Houston space leader as new president

moving up

Houston-based Aegis Aerospace's current chief strategy officer, Matt Ondler, will take on the additional role of president on Jan. 1. Ondler will succeed Bill Hollister, who is retiring.

“Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers,” Stephanie Murphy, CEO of Aegis Aerospace, said in a news release.

Hollister guided Aegis Aerospace through expansion and innovation in his three years as president, and will continue to serve in the role of chief technology officer (CTO) for six months and focus on the company's technical and intellectual property frameworks.

"Bill has played an instrumental role in shaping the success and growth of our company, and his contributions leave an indelible mark on both our culture and our achievements," Murphy said in a news release.

Ondler has a background in space hardware development and strategic leadership in government and commercial sectors. Ondler founded subsea robots and software company Houston Mechatronics, Inc., now known as Nauticus Robotics, and also served as president, CTO and CSO during a five-year tenure at Axiom Space. He held various roles in his 25 years at NASA and was also named to the Texas Aerospace Research and Space Economy Consortium Executive Committee last year.

"I am confident that with Matt at the helm as president and Bill supporting us as CTO, we will continue to build on our strong foundation and further elevate our impact in the space industry," Murphy said in a news release. "Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers."

Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

neuro research

Rice University launched its new Amyloid Mechanism and Disease Center last month, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases.

The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established.

The team will work to ultimately increase its understanding of amyloid processes and will collaborate with the Texas Medical Center to turn lab discoveries into real progress for patients. It will hold its launch event on Jan. 21, 2026, and hopes to eventually be a launchpad for future external research funding.

The new hub will be led by Pernilla Wittung-Stafshed, a Rice biophysicist and the Charles W. Duncan Jr.-Welch Chair in Chemistry.

“To make a real difference, we have to go all the way and find a cure,” Wittung-Stafshede said in a news release. “At Rice, with the Amyloid Mechanism and Disease Center as a catalyst, we have the people and ideas to open new doors toward solutions.”

Wittung-Stafshede, who was recruited to Rice through a Cancer Prevention and Research Institute of Texas grant this summer, has led pioneering work on how metal-binding proteins impact neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Her most recent study, published in Advanced Science, suggests a new way of understanding how amyloids may harm cells and consume the brain’s energy molecule, ATP.

According to Alzheimer’s Disease International, neurodegenerative disease cases could reach around 78 million by 2030 and 139 million by 2050. Wittung-Stafshede’s father died of dementia several years ago.

“This is close to my heart,” Wittung-Stafshede added in the news release. “Neurodegenerative diseases such as dementia, Alzheimer’s and Parkinson’s are on the rise as people live longer, and age is the largest risk factor. It affects everyone.”

This Houston airport saw sharp passenger decline in 2025, study shows

Travel Talk

A new global airport travel study has revealed passenger traffic at Houston's William P. Hobby Airport (HOU) sharply decreased from 2024 to 2025.

The analysis from travel magazine LocalsInsider examined recently released data from the Bureau of Transportation Statistics (BTS), the U.S. International Trade Association, and a nationwide survey to determine the following American traveler habits: The most popular U.S. and international destinations, emerging hotspots, and destinations on the decline. The study covered passenger travel trends from January through July 2025.

In the report's ranking of the 40 U.S. airports with the sharpest declines in passenger traffic, HOU ranked 13th on the list.

About 4.26 million arrivals were reported at HOU from January through July 2024, compared to about 3.96 million during the same seven-month period in 2025. According to the data, that's a significant 7.1 percent drop in passenger traffic year-over-year, or a loss of 300,974 passengers.

"As travelers chase new hotspots, some destinations are seeing reduced passenger traffic whether due to rising costs, shifting airline schedules, or evolving traveler preferences, some destinations are seeing a decrease in visitors," the report's author wrote.

It appears most major Texas airports had drops in passenger traffic from 2024 to 2025. Dallas Love Field Airport (DAL) saw the worst in the state, with a dramatic 7.4 percent dip in arrivals. DAL also ranked 11th on the list of U.S. airports with the steepest declines in passenger traffic.

More than 5.13 million arrivals were reported at DAL from January through July 2024, compared to over 4.75 million during the same seven-month period in 2025.

This is how passenger traffic has fallen at other major Texas airports from 2024 to 2025:

Austin-Bergstrom International Airport (AUS):

  • 6,107,597 – Passenger arrivals from January to July 2024
  • 5,828,396 – Passenger arrivals from January to July 2025
  • -4.6 percent – Year-over-year passenger change
Dallas/Fort Worth International Airport (DFW):
  • 23,830,017 – Passenger arrivals from January to July 2024
  • 23,251,302 – Passenger arrivals from January to July 2025
  • -2.4 percent – Year-over-year passenger change

San Antonio International Airport (SAT):

  • 2,937,870 – Passenger arrivals from January to July 2024
  • 2,836,774 – Passenger arrivals from January to July 2025
  • -3.4 percent – Year-over-year passenger change
El Paso International Airport (ELP):
  • 1,094,431 – Passenger arrivals from January to July 2024
  • 1,076,845 – Passenger arrivals from January to July 2025
  • -1.6 percent – Year-over-year passenger change
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This story originally appeared on CultureMap.com.

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