Houston 3D printing co. moves forward to next phase of NSF accelerator

sustainability in mind

Re:3D has moved onto the next phase of a NSF program focused on circular economy innovation. Photo via re3d.org

An innovative project led by Houston-founded re:3D Inc. is one of six to move forward to the next phase of the National Science Foundation's Convergence Accelerator that aims to drive solutions with societal and economic impact.

The sustainable 3D printer company will receive up to $5 million over three years as it advances on to Phase 2 of the program for its ReCreateIt project, according to a statement from the NSF. Co-funded by Australia's national science agency, the Commonwealth Scientific and Industrial Research Organisation, or CSIRO, ReCreateIt enables low-income homeowners to design sustainable home goods using recycled plastic waste through 3D-printing at its net-zero manufacturing lab.

The project is in partnership with Austin Habitat for Humanity ReStores and researchers from the University of Wollongong and Western Sydney University. CSIRO is funding the Australian researchers.

In Phase II the teams will receive training on product development, intellectual property, financial resources, sustainability planning and communications and outreach. The goal of the accelerator is to promote a "circular economy," in which resources are reused, repaired, recycled or refurbished for as long as possible.

"Progress toward a circular economy is vital for our planet's health, but it is a complex challenge to tackle," Douglas Maughan, head of the NSF Convergence Accelerator program, said in the statement. "The NSF Convergence Accelerator program is bringing together a wide range of expertise to develop critical, game-changing solutions to transition toward a regenerative growth model that reduces pressure on natural resources, creates sustainable growth and jobs, drastically reduces waste and ultimately has a positive impact on our environment and society. Phase 2 teams are expected to have strong partnerships to ensure their solutions are sustained beyond NSF support."

Other teams that are moving forward in the accelerator include:

FUTUR-IC: A global microchip sustainability alliance led by MIT
PFACTS: Led by IBM's Almaden Research Center and aiming to replace, redesign and remediate fluorine-containing per- and polyfluoroalkyl substances (PFAS)
SOLAR: A team led by Battelle Memorial Institute using photovoltaic circularity to develop the technology needed to achieve sustainable solar recycling
SpheriCity: A cross-sector tool that examines how plastics, organics and construction and demolition materials flow through local communities developed by the University of Georgia Research Foundation Inc.
Topological Electric: Another MIT-led team, this group aims to develop electronic and energy-harvesting device prototypes based on topological materials.

Re:3d and 15 other teams were first named to the Convergence Accelerator in 2022 with a total investment of $11.5 million. At the end of Phase 1, the teams participated in a formal Phase 2 proposal and pitch, according to the NSF. The Convergence Accelerator was launched in 2019 as part of the NSF's Directorate for Technology, Innovation and Partnerships.

This is the latest project from re:3D to land national attention and funding. Last year the company was one of 12 to receive up to $850,000 from NASA's SBIR Ignite pilot for its project that aimed to develop a recycling system that uses a 3D printer to turn thermoplastic waste generated in orbit into functional and useful objects, according to the project's proposal.

In 2022, it was also among the winners of an inaugural seed fund expo from the U.S. Small Business Administration. It also earned the prestigious Tibbetts Award from the SBA in 2021. The award honors small businesses that are at the forefront of technology.

Re:3D Inc. was founded in 2013 by NASA contractors Samantha Snabes and Matthew Fiedler and is based in Clear Lake. It's known for its GigaBot 3D printer, which uses recycled materials to create larger devices. The company announced its new Austin headquarters earlier this year.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

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