Support Houston startups by shopping local this holiday season. Photo via Getty Images

It's giving season, and you need not look any further than Houston's startup and innovation community for some gift ideas.

This year's Houston startup gift guide includes experiences, sustainable shopping, and more.

Need some more ideas? Browse last year's roundup of Houston startup-created gift ideas, and check out the 2021, 2020 and 2019 startup gift guides as well for even more options.

For someone outdoorsy: An easy-to-book fishing trip

Mallard Bay, which won big at the Rice Business Plan Competition, expanded in Houston this year. Photo via Getty Images

After seeing success in last year's Rice Business Plan Competition, Mallard Bay, a marketplace for booking guided fishing and hunting trips, announced this year that it's moving half of its employees to Houston, InnovationMap reported. The company hopes the move will help it tap into the large corporate and convention entertainment market in Texas. You can book a trip for your family or shop gear on the startup's website.

For a wine lover: A quick cooling tool

The Cold Cork delivers 20-second beverage chilling. Photo via Facebook/Cold Cork

Perfect for someone who loves to entertain, The idea Cold Cork came from the brains of two Houstonians who love a chilled wine at the end of a long day. However, it often happens that while you're ready for wine, but the wine's not ready for you. The device, priced at $64.95, chills liquids 20 degrees in 20 seconds.

For the new mom in your life: A game-changing breastmilk service

Milkify secured a deal on Shark Tank. Photo courtesy of Milkify

As seen on Shark Tank, Houston-based Milkify provides a unique service to breastfeeding moms. The company freeze dries breast milk so that families can have the convenience of formula with the nutrition of breast milk. The startup, which won at this year's Houston Innovation Awards, secured an investment on the show and even got the nod of approval from Gwyneth Paltrow. Milkify has plans to scale, as the husband-and-wife team shared on the Houston Innovators Podcast.

For someone who loves a sweat sesh: Smell-free athletic wear

Houston-based Accel Lifestyle's innovative line of athleisure has made it into Talbots. Photo courtesy of Accel Lifestyle

For years, Houston athletic clothing brand Accel Lifestyle has been providing its customers with sporty outfits that are designed to not hold onto any stink resulting from bacteria from sweat. As of this summer, the brand is in Talbots, so you can shop in store, as well as online.

For the trendsetter: Sustainable fashion

A Houston innovator found second-hand shopping time consuming. So, she designed a better experience. Image courtesy of Trendy Seconds

Shop for one (or all) of your loved ones sustainably with Trendy Seconds, a website created by Houstonian Maria Burgos. There's likely something for everyone on your Christmas list — and no purchase can possibly considered naughty — at least when considering your carbon footprint.

For a party animal: Brews for every occasion

Bring these to your next holiday party. Photo by Emily Jaschke/InnovationMap

Two Houston companies formalized their partnership this year. Bayou City Hemp Company announced that it has purchased 8th Wonder Brewery, Distillery, and Cannabis. The acquisition deepens a relationship that dates back to 2021, when 8th Wonder and Bayou City Hemp partnered to create Wonder Water, a non-alcoholic beverage available with either CBD or Delta-8 that became the top-selling to-go product at 8th Wonder. Now, the combined company creates adult beverages by offering a full lineup of beer, spirits, and cannabis-infused drinks.

For a mother-daughter duo: A tool to enhance their relationship

Houston startup addresses mother-daughter dynamic with first app of its kindA Houston-founded company is targeting mothers and daughters with their teletherapy app. Photo courtesy of Passport Journeys

Passport Journeys, an app with a membership that helps cultivate mother-daughter relationships, can help you on your new year's resolution to heal your relationship with your mom or daughter. The intake process is $280 with monthly fees after and includes a slew of support for relationship building.

An innovative, Houston-created tool instantly chills wine and spirits. Photo via thecoldcork.com

Innovative Houston couple designs wine-cooling device

drink this in

Great inventions reveal their value within due course, but there are those creations that tell their worth almost immediately, with a first look, image, or mere mention.

The Cold Cork, a malleable pouring device that instantly chills wine and spirits, falls into that category.

It seems like such a simple idea, but that’s the thing about inventions, isn’t it? Anyone can come up with an idea, but it’s the ones that can execute that idea that make it to the finish line and etch their names in the annals of creative glory.

“I had come home from the grocery store, right at the onset of COVID, and I wanted to have a glass of wine that I bought, but it was already room temperature, and I didn't want to put ice in it,” says wine-lover and former healthcare worker Michelle Kurkiewicz. “So, we started doing some research and came up with the idea for Cold Cork.”

Timing is everything, and because the nationwide pause caused by the COVID-19 pandemic offered Michelle, 33, and her husband Tyler, 30, plenty of free time, the dutiful duo was able to flesh out their labor of love.

Tyler and Michelle Kurkiewicz came up with the idea of the Cold Cork. Photo via thecoldcork.com

As it turns out, Tyler, a mechanical engineer by trade, had recently purchased a 3D printer back in January 2020, so he was able to use it to build hundreds of prototypes in-house to eventually arrive at a final design, which is based on the couple’s wedding champagne flutes.

So how does the Cold Cork work? Picture this: the wine-lover takes the Cold Cork out of the freezer (after a recommended 24 hours to thoroughly freeze), places it on top of the open bottle of wine and begins to pour.

As the liquid funnels through the stainless-steel coil, which is surrounded by a proprietary, food-grade cooling medium, the wine or spirits is chilled by 20 degrees in just 20 seconds.

To achieve the best results for red wine, pour the entire bottle through the Cold Cork into a decanter and enjoy.

And the best part? Not one part of the Cold Cork’s signature process alters the taste or composition of the drink in any way.

The device, priced at $64.95, chills liquids 20 degrees in 20 seconds. Photo via thecoldcork.com

“At first, we thought about whether the product should be inside the bottle or outside the bottle,” remembers Tyler. “But we quickly realized that there’s simply not enough room to do that amount of chilling inside a bottle. And we didn't want to have to pour any wine out. But we needed to make space to put some sort of chiller in the bottle. And so, we immediately started looking outside the bottle, and just with all the other wine gadgets, being bottle-topped and plugging in with a rubber stopper, that's immediately the direction we sort of drifted to.”

According to Tyler, the first couple of prototypes were made of a 3D filament. Initially, the idea was to focus on creating a cooling gel to compliment the coil, but that got a bit messy and, of course, there were too many wine taste-testing sessions to count.

“We definitely went through a lot of bottles of wine,” says Michelle. “But one of the first people that used our product was a sommelier and she loved it. We also gave one of our first production-level prototypes to a friend who is a manager at a restaurant. She used it on several occasions and said it was perfect for what she needed and seeing our product be used at a place that we frequented was extremely validating.”

Armed with the validation they needed to go to production, the wine-loving public could now have the product they needed to keep from having to throw all their wine in the refrigerator.

“The Cold Cork is really good for the people that maybe don't have those multi-zone fridges,” says Michelle. “We found a good niche with entry-level wine drinkers that don't have a wine fridge, but they want to drink their white wines still without being over-drank with ice cubes.

“That's really who we've been going after, and who we've seen has found a lot of value in the product. It's really the people that maybe aren't so prepared or maybe looking just for some more accessible solutions, whether it's because of the space in their apartment or financially, you know, it might be cheaper than a wine fridge. That's why we came up with the Cold Cork ourselves, because that was us, and so we kind of made a product that worked for us and found that there are a lot of people like that.”

The Cold Cork is available now and can be purchased directly from the company’s website for $64.95. In the future, more cork sizes and different colors will be offered, and more brick-and-mortar stores will carry the product. The couple pitched the idea and received investment from Trend Ventures at the 2022 Build Up Buttercup, an initiative that featured small business pitches for a select group of investors.

“We’ve gotten a lot of feedback directly from customers saying they use it a lot more than they thought,” says Michelle. “But then there are those people that are skeptical about how it works. That’s why I love to demo the Cold Cork in person.”

For a couple that met at a bar one night in downtown Houston, the Cold Cork is almost a poetic destination as a business endeavor and one that they both really relish.

“We both have our strengths, and we give each other a lot of support,” says Michelle.

“I’m very mechanically inclined, so I develop and invent, and Michelle is great with the marketing aspect and working with people to purchase the product,” adds Tyler. “In addition to the Cold Cork, we do have a couple of early projects that we are working on. I think there is a lot of opportunity with our technology to take what we have learned and fit that into different product lineups moving forward.”

Cold Cork Thermometer Test

Dede Raad of Dress Up Buttercup created a unique pitch series — completely fueled by her social media community — that gave a spotlight to eight businesses. Photo via dressupbuttercup.com

Houston fashionista fuels fresh brands with pitch series

money moves

After growing her audience to over a million followers on Instagram, Houston fashion blogger Dede Raad felt the pressure to expand her business — but she didn't feel inspired by any particular line of business to grow into.

"In the blogging world, which I've been doing for about seven years, everyone's next step is to start a brand and to start something of their own," Raad, founder of Dress Up Buttercup, tells InnovationMap. "I just don't have anything in my heart that I was really passionate about. I know once you start something, you have to give it your all."

But what Raad realized — after a year of thinking about her next move and a chance viewing of Shark Tank — was that tons of business founders were passionate about their own brands, and there was an opportunity for Raad use her community to support them instead of coming up with something of her own.

She put the call out to her followers to find founders with growing brands. Raad launched "Build Up Buttercup," an initiative that featured small business pitches for a select group of investors, with her husband, Ted. The event, which happened last October, resulted in eight business pitches across four episodes uploaded to Dress Up Buttercup's page that garnered hundreds of thousands of views. The initiative also resulted in a handful of investments and cash prizes.

"It was a crazy four days, but it was so cool to see the brands and the passion behind it and for Ted and I to help in both a financial and advising way," Raad says.

Raad was joined at the event with fellow investors, which included Houston-based investment firms Curate Capital and Trend Ventures, the investment arm of influencer management company Trend Management, founded by Ted Raad.

Of the eight that pitched, four companies received investments. Dress Up Buttercup invested in Houston-based jewelry company Burdlife and children's clothing brand Poppy Kids. Trend Ventures made investments in Cold Cork and Houston-based tech startup, AIM7, which closed its seed round in December.

Raad tells InnovationMap that she'd be interested in hosting another edition of "Build Up Buttercup" in the future, but for now she's focused on her two new brands. Her role within both of the companies is very hands on, she explains, and meets with the founders at least once a week. She also markets both brands to her Instagram community.

"We're not just sending you a check — we want to be involved," Raad says. "I've worked with brands for the past seven years, and I've seen what people are buying. I have such a power in my community, and I know what they like."

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Houston researchers develop dissolvable implant for targeted cancer drug delivery

cancer research

Researchers at Houston Methodist have developed a biodegradable implant that can be used to safely and consistently deliver drug treatments to tumors and then dissolve without the need for further surgery.

The implant is only the size of a grain of rice, but its potential is staggering. The biodegradable nanofibrous drug-eluting seed (b-NDES) works as a reservoir parked inside a soft tumor, where it can slowly release immune-stimulating drugs over time. This overcomes a consistent problem with drugs such as immune checkpoint inhibitors. Normal systemic administration sees comparatively little of the drug making its way to the tumor, with most of it circulating throughout the body. The b-NDES is like deploying a small guerrilla fighting force embedded in enemy territory, doing maximum damage to the entrenched tumor.

"To improve cancer treatment, we're trying to start a fire inside the tumor itself," Corrine Chua, associate professor in the Center for BioNanoengineering at Houston Methodist Research Institute, said in a news release. "By activating immune cells directly within the tumor microenvironment, those cells can then travel throughout the body and seek out cancer wherever it exists. The b-NDES platform was developed to help keep therapeutic drugs concentrated inside tumors while minimizing exposure to healthy tissues.”

Chua co-led the study with Alessandro Grattoni, chair and director of the Center for BioNanoengineering at Houston Methodist Research Institute.

The study included support from the Nancy Owens Breast Cancer Foundation and the National Institutes of Health/National Cancer Institute.

Chau and Grattoni used preclinical models of triple-negative breast cancer, an aggressive form of cancer that is estrogen receptor-negative, progesterone receptor-negative and HER2-negative. Because of the receptor negativity, some popular treatments like tamoxifen and trastuzumab are ineffective. Chemotherapy has been shown to be the best course of action.

The b-NDES implant is deployed alongside radiation drugs. It keeps the drugs focused on the tumor, reducing the amount of harmful side effects typically seen when drugs are circulated more widely in the body. In 60 percent of the models, tumors were eliminated and did not cause side effects beyond the tumor site. Once the drugs have been deployed, the implant breaks down naturally.

While promising, more research will have to be done to expand use to other tumor types.

"Although the study focused on triple-negative breast cancer models, the approach could have broader applications for solid tumors," Grattoni added in the release. "It could potentially be used in cancers where there is a tumor lesion accessible for placement, including pancreatic or lung cancers."

New Houston platform Same Day Reels launches for on-demand content creation

In The Moment

If an event doesn't happen on Instagram, did it even really happen? In today's social media-driven age of branding and audience engagement, the answer increasingly is no.

Houston entrepreneur Karen De Amat is looking to fill the online content creation needs of companies with her new venture, Same Day Reels, which launched in early August. It will serve as a platform to connect companies and brands with talent that can help turn an event into a viral moment as it is happening.

"Events move quickly, and social media moves even faster,” said De Amat. “Same Day Reels was built to help brands capture the moment while it still matters. We are creating a more efficient way for businesses and creators to work together. Brands need content faster, and creators need more opportunities to turn their talent into real work. Same Day Reels brings those needs together.”

The company is focused on adding livestreams and concurrent short video content to "activations, launches, fundraisers, grand openings, conferences, hospitality experiences, and private celebrations." Such content can significantly increase the visibility of a product or brand according to digital marketing brands like Wyzowl, whose data found 63 percent of people in 2026 prefer to learn about new products via short video.

Packages offered by Same Day Reels will include filming, editing, and publishing content within hours of the targeted event.

De Amat says that her content creation platform will be a way to preserve the excitement of events and launches by enshrining them with immediate social media-driven memories.

“Event content is no longer just something you post after the fact,” De Amat said. “It is part of how people experience, remember and share the moment.”

Previously, De Amat is also the founder and CEO of Social Behavior, an influencer marketing company she launched from her home in 2014. It quickly garnered an array of clients and thrust De Amat into the spotlight, including numerous appearances on Fox 26's The Isiah Factor. Influencer Marketing Hub named her one of the top CEOs of influencer marketing companies in Houston in 2025.

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This article originally appeared on CultureMap.com.

Bristol Myers Squibb to build $2.3B Houston pharma manufacturing campus

coming soon

New Jersey-based pharmaceutical giant Bristol Myers Squibb Co. has officially named Houston as the home of its new state-of-the-art manufacturing site.

The 60,000-square-foot facility represents a $2.3 billion investment, according to a news release. It is expected to create 500 skilled jobs and will be located in Houston's Generation Park.

BMS first announced that it was considering Houston among 16 other cities for the facility in May. The new hub will manufacture small molecule, biologic and antibody-drug conjugates and is part of a $40 billion commitment to invest in the United States over five years. Construction is slated to begin next year, with the facility coming online in 2030.

"We're building the domestic manufacturing capabilities needed to deliver the next generation of medicines and support future scientific breakthroughs. Houston and the state of Texas offer the talent, infrastructure, and partnership needed to help bring that vision to life," Christopher Boerner, CEO and board chair of BMS, said in the release.

The new facility will feature a modular, multi-modal design, which will allow the company to reconfigure and add to its manufacturing capabilities over time. BMS says it expects the facility to "(grow) in scale and capability well beyond its opening configuration."

"Our decision to build this state-of-the-art manufacturing campus in Houston, Texas, reflects our confidence in the region’s ability to support a world-class, digitally advanced supply operation,” Karin Shanahan, EVP and chief supply chain and operations officer of BMS, added in the release. “This facility is designed to deliver the speed, quality, and reliability that patients depend on, combining flexible, modular manufacturing with advanced digital capabilities to ensure consistent supply across multiple modalities. It strengthens our ability to operate with resilience and positions us to reliably deliver medicines to patients today while adapting future demands.”

Texas Gov. Greg Abbott shared that the state has granted BMS a $4.89 million Texas Enterprise Fund (TEF) grant for the project. TEF grants, administered by the Texas Economic Development & Tourism Office, support business relocation or expansion projects that create "new, good-paying jobs in the community and attract significant new capital investment to the state." The development is also a qualified project under the Texas Jobs, Energy, Technology, and Innovation (JETI) program.

“Texas is a global hub for life sciences, where today’s innovations shape the future of healthcare,” Abbott said in a news release. “This $2.3 billion investment by Bristol Myers Squibb in the dynamic biotech ecosystem in Houston is a testament to the depth of our skilled workforce and the pipeline of talent coming through our nation-leading technical colleges and research universities. With lower operating costs and easy access to markets across the U.S. and the world, Texas drives affordability for consumers.”

"Bristol Myers Squibb’s announcement is a tremendous win for Texas and the Houston region, further reinforcing our position as a premier destination for life sciences and advanced manufacturing,” added Greater Houston Partnership President and CEO Steve Kean.

Last fall, Eli Lilly and Co. selected Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.