The Ion announces new tenants that have recently moved in, expanded within the hub

moving in

The Ion has announced the latest companies to move into the hub. Photo courtesy of The Ion

Several organizations — from tech startups to a nonprofit — have moved into the Ion recently to either relocate or expand their presence in Houston.

The Ion District announced new tenants today, bringing the total space leased to 86 percent, according to a news release. The recent additions to the Ion include:

Carbon Clean announced its new United States HQ last month. The startup’s technology has captured nearly two million tons of carbon dioxide at almost 50 sites around the world.
Cognite is a Norwegian software company for asset-heavy industries that turns industrial data into customer value.
OpenStax, a Houston-based nonprofit, is publishing openly licensed college textbooks that are free online and low cost in print.
Synopic is a California-based startup that's building next-gen depth-enabled cameras to improve visualization and decision making during medical procedures.
Houston-based Motif Neurotech, a medical equipment manufacturing startup, is working to develop minimally invasive electronic solutions for mental health.
RedSwan CRE, founded in Houston, is a crowdfunding-style investment platform and marketplace of tokenized commercial real estate.
Nauticus Robotics, a marine robotics hardtech and software company, recently went public.
Rice University’s Office of Innovation and its Nexus Lab, which is under construction and designed for prototyping and scaling-up technologies, is increasing its presence in the Ion.
Also noteworthy is the expanded office of Ara Partners, which first moved into the Ion last year. The Houston-based, global private equity firm is focused on investing in carbon decentralization technology.
Dallas-headquartered flexible workspace provider Common Desk announced that it would expand its space by nearly 50 percent at the Ion last December.

“Welcoming this amazing lineup of new tenants, across the breadth of sectors they represent, demonstrates that the Ion is the place to be and do business in Houston,” says Jan E. Odegard, executive director of the Ion, in the news release. “By continuing to fill our space with new innovators across all these different offerings, from all around the globe, we’ve become the home for collisions that will create solutions to the biggest problems facing our world today.

"We pride ourselves on advancing the diverse knowledge, teams, technologies, and products that will propel our world forward. Our inspiring new tenants will do just that,” he continues.

The Ion's grand opening took place just about a year ago, and existing tenants include Chevron, Microsoft, (Schlumberger) SLB Innovation Factori, Houston Methodist. The growing Ion District is home to more than 300 businesses, including corporates, small businesses, startups, and restaurants.

“The Ion continues to see leasing demand from companies that understand the value of a creative and active work environment,” says Bryson Grover, investment manager of real estate development at Rice Management Co. “Companies are choosing Ion District because it offers more than just a solution for space needs. Workers are given the opportunity to experience a sense of community that brings together like-minded individuals and those with different perspectives.”

From Your Site Articles

The new programming geared at idea-stage startups has officially commenced at TMC Innovation Institute. Courtesy of TMCx

New TMCx program launches, C-level execs named at Houston startups, and more innovation news

Short stories

There's been a lot of recent Houston innovation news, and you might have missed something. Keep up to date with all the news happening among startups and technology in Houston in this innovation news roundup.

If you know of innovation-focused news happening, email me at natalie@innovationmap.com with the details and subscribe to our daily newsletter that sends fresh stories straight to your inboxes every morning.

TMCalpha premieres

Courtesy of TMC

The Texas Medical Center has long counseled budding medical entrepreneurs in various capacities through its TMC Innovation Institute, but wanted to introduce programming specifically for early-stage companies. That's how TMC alpha was born and announced at the most recent TMCx Demo Day.

The program officially launched on July 18 and will host meetups on the third Thursday of every month.

"Over the past five years, TMC Innovation has blossomed into a global proving ground for healthcare startup companies from across the world, and we could not be more pleased with the myriad ways in which the ecosystem here has expanded in nature," says TMC Innovation Director Tom Luby in a release. "That being said, we realized that TMC Innovation needed to do more for the local innovation community and offer ample resources to support homegrown talent from within the confines of the largest medical city in the world. With TMC alpha, the hope is to connect anyone with a fledgling healthcare idea to the TMC Innovation network and create a two-way channel of meaningful dialogue."

Innowatts scores extra funding and names new C-level exec

Photo via innowatts.com

Houston-based AI-enabled analytics company, Innowatts, is growing in more ways than one. The company, which is fresh off an over $18.2 million Series B fundraise, added move funds and a new C-level executive.

Veronorte, a South American venture capital firm backed by one of the largest utilities in Colombia, became an additional investor in the company with an undisclosed contribution. Meanwhile, Eric Danziger joined the company as its new chief revenue officer. He will be tasked with the growth and sales of Innowatts' eUtility™ product.

"As the utility grid becomes more complex with the proliferation of electric vehicles and distributed generation," says Danziger in a release, "utility companies have to adapt to the data generated and needs of their consumers to manage these complex requirements."

Startup snags free office space prize

Photo courtesy of The Cannon

Shoot, a digital marketplace that simplifies the photographer and videographer booking process, has scored free office space in the newly opened Cannon building after receiving the second annual Insperity Innovation Scholarship.

The company was co-founded by Simbai Mutandiro and Alina Merida and has already launched its beta platform. The company will release its next version of the platform soon.

"Our relationship with The Cannon and the Insperity Innovation Scholarship are part of our initiative to help startups become successful more quickly by connecting and collaborating with like-minded individuals," says Larry Shaffer, Insperity senior vice president of marketing and business development, in a release. "We congratulate Shoot on receiving this scholarship and wish the co- founders continued success in furthering their entrepreneurial dream."

The other three finalists in the contest — Delfin, Social Chains, and SOTAOG — will receive open desk memberships at The Cannon for six months.

Houston falls low on the list of cities booming with growing private companies

Getty Images

When it comes to the major metros with the biggest jump in private businesses with over $1 million in revenue, Houston is the last on the list for Texas cities. LendingTree looked at the data, and, between 2014 and 2016, Houston only saw an increase of 4.9 percent in million-dollar business growth. This earned the Bayou City a No. 32 ranking across the country.

Dallas was slightly ahead of Houston with 5.2 percent growth and a No. 29 rank. Meanwhile, Austin earned the top spot with 15.1 percent growth. San Antonio, the only other Texas metro in the study, ranked No. 12 with 9 percent growth.

Nesh forms partnership

Photo courtesy of Thomas Miller/Breitling Energy

The Woodlands-based WellDatabase has announced a partnership with Nesh, an AI-optimized tool that's like the Siri or Alexa of oil and gas.

"The technology is amazing and we are thrilled to work with the Nesh team," writes John Ferrell, CEO of WellDatabase, in a blog post. "The integration allows Nesh to run real-time queries against WellDatabase. Users can ask a multitude of questions and get instant answers. They can also work with the Nesh team directly to train and build new questions and workflows."

Rice University and Cognite join forces

Courtesy of Cognite

When Oslo, Norway-based Cognite announced its dual U.S. headquarters in Houston and Austin, it had plans to engage universities from the get go. Now, the company, which specializes in data software with industrial applications, has officially created a partnership and internship program with Rice University.

"This partnership illustrates Cognite's commitment to attracting top people to build the most talented software engineering team in the world," says John Markus Lervik, Cognite co-founder and CEO, in a release. "Cognite solves some of the most complex problems related to industrial digitalization. To do that, we need the best minds, so partnering with Rice University was a natural choice."

Rice students are currently in Norway this summer working for Cognite as a part as the inaugural program.

The Cannon teams up with Thompson & Knight

Courtesy of The Cannon

Houston-based law firm Thompson & Knight has officially signed on to provide resources for The Cannon startups in a strategic partnership between the two companies.

"Thompson & Knight is pleased to partner with Houston-based entrepreneurs who are building the innovation, services, and technological platforms of the very near future," says Mark M. Sloan, managing partner of Thompson & Knight, in a news release. "We will offer our experience in the issues common to startup businesses, including intellectual property, technology, corporate, labor, and other areas of counsel that will help further the goals of these pioneering companies."

The law firm will have an office in The Cannon's recently opened building in West Houston.

Solugen names president

Getty Images

In May, Houston-based chemicals company, Solugen Inc., closed a $32 million round. Now, the company has put a portion of that money to work to hired the newest executive on the team. Jason Roberts, who has a decade of chemicals and oil and gas experience, has joined Solugen as president.

"What I found most compelling about Solugen was the company's quick successes and their overarching goal of decarbonizing the chemicals industry," says Roberts in a release. "The company's fundamental chemistry and technologies have created products that no one in the industry currently has. I am excited to join this young company's fast moving team at such a significant time in its history and look forward to helping scale their innovative products and services."

From oil and gas to space technology, these leaders are pushing forward innovation in Houston. Courtesy photos

3 Houston innovators to know this week

Who's who

One thing this week's movers and shakers in the Houston innovation ecosystem have in common is their intention to disrupt an industry using technology. Here are this week's innovators you need to know in Houston.

Francois Laborie, general manager of Cognite North Americas

Courtesy of Cognite

When it comes to data, most energy companies are squandering valuable information by not properly using their data. Cognite, which has its US headquarters in Texas, has solutions, says general manager of the company, Francois Laborie.

"Standardizing APIs across the oil and gas industry would open the door to a community of developers, which could create custom applications and connect existing market solutions," he writes in a guest column for InnovationMap. "Then more new and exciting applications and services would reach the market faster."

Click here to read Laborie's article on the importance of APIs and data management.

Steven Gonzalez, technology transfer strategist at NASA

Courtesy of NASA

Houston is the Space City — present tense. While the city has a rich history as a major player in aerospace exploration and engineering, Houston is far from done, Steven Gonzales, NASA technology transfer strategist, tells InnovationMap.

We've always been the Space City, but for a while there, it was taken for granted. It's part of our history, but it's nice to see it brought back into the foreground to realize that it's not just history, it's who we are today.

Click here to read our Space City Month feature on Gonzalez in which he explains Houston's future in space and how NASA wants to work with startups.

Christine Galib, program director of The Ion Smart Cities Accelerator

Courtesy of Station Houston

Christine Galib has a new gig in town. The former Rice University and St. Thomas University educator is now the program director of the Ion Smart Cities Accelerator, a program that will find and grow startups with solutions to Houston's biggest problems.

"When we look at The Ion being created as a center for entrepreneurship and innovation in Houston, there's no other city in the world has this type of level of collaboration and transparency of major players in the innovation space coming together to create, not only the physical space, but also the programming and mindset and the environment and the culture to sustain it," she tells InnovationMap.

Click here to read more about Galib and what she's excited to bring to town.

Using APIs, organizations can more easily combine their own internal data. Getty Images

Energy companies need to integrate new functions in order to better utilize data, says this expert

Houston, home to one of Cognite's U.S. headquarters, is the energy capital of the world. But while many oil and gas industry players and partners come together here, much of the data they use — or want to employ — remains siloed.

There's no lack of data. Connected devices are a wellspring of enterprise resource planning data, depth-based trajectories, piping and instrumentation diagrams, and sensor values. But incompatible operational data systems, poor data infrastructure, and restricted data access prevent organizations from easily combining data to solve problems and create solutions.

We understand these challenges because we work alongside some of the biggest operators, OEMs and engineering companies in the oil and gas business. Lundin Petroleum, Aker Energy OMV, and Aker BP are among our customers, for example.

Flexible, open application programming interfaces can address the challenges noted above. APIs enable users to search, filter and do computations on data without downloading full data sets. And they abstract the complexity of underlying storage formats.

As a result, data scientists and process engineers can access data in an efficient manner, spending more time on their use cases and less effort contending with technical details. Using APIs, organizations can more easily combine their own internal data. APIs also simplify the process of using data from industry partners and other sources.

Most companies have slightly different work processes. But common API standards can help a company combine software services and platforms from others in a way that matches its own business logic and internal processes. That can allow the company to differentiate itself from competitors by employing services from the best suppliers to create innovative solutions.

Standardizing APIs across the oil and gas industry would open the door to a community of developers, which could create custom applications and connect existing market solutions. Then more new and exciting applications and services would reach the market faster.

To ensure adoption and success of such a standardization effort, the APIs would need to be well crafted and intuitive to use. These APIs would have to include the business logic required to perform the operations to empower users. In addition, APIs would need to define and allow for the sharing of desired information objects in a consistent way.

Best practices in defining common APIs for sharing data within the industry include:

Introducing APIs iteratively, driven by concrete use cases with business value
Ensuring all services using the API provide relevant output and insights in a structured machine-readable format, enabling ingestion into the API to ensure continuous enrichment of the data set
Making all data searchable
Preventing underlying technology from being exposed through the APIs to ensure continuous optimization and allow companies to implement their technology of choice
Supporting all external data sharing through an open, well-documented and well-versioned API, using the OpenAPI standard

If oil and gas industry operators define APIs, suppliers will embrace them. That will "grease" the value chain, allowing it to move with less friction and waste.

Operations and maintenance are a natural place for API harmonization to start. Standardized APIs also can enable operators to aggregate and use environmental, equipment and systems, health and safety, and other data. That will accelerate digital transformation in oil and gas and enable companies to leverage innovative solutions coming from the ecosystem, reduce waste, and improve operations, making production more sustainable.

------

Francois Laborie is the general manager of Cognite North Americas.

Cognite is opening two offices in Texas. Getty Images

European software company plans first U.S. office in Houston

New to town

When considering entering the United States market, Francois Laborie, general manager of Cognite North Americas, of course considered some of the obvious cities for a regional headquarters.

"Initially, when we talked about the US, people assumed Silicon Valley or Boston, because we are a traditional software company," Laborie says. "But we really didn't consider too long because the customers we work with require a pretty deep understanding of industry."

The Norway-based company decided to bet on the energy capital of the world and has announced future offices in Houston as well as Austin — both to open by this summer. This will be Cognite's first expansion outside of Northern Europe. The company makes data software for industrial businesses — oil and gas being a huge focus, as is engineering, equipment manufacturing, shipping, and more.

"The industrial world is very siloed and closed, and we are changing a lot of things in that world," Laborie says. "In the digital world, data and information only becomes valuable as you share it. We are all about liberating data, contextualizing it, and then drawing value out of it."

Laborie says the Houston office will be the company's energy hub — both current and prospective clients of Cognite have pressences in town. Meanwhile, Austin will be the tech hub, since the city has a large tech talent pool. Currently, Austin is on the path to be the U.S. headquarters, but nothing is set in stone at the moment, Laborie says.

Cognite, which expects around 50 employees (both new hires and relocations) split between the two locations, already has strategic Houston partnerships in place. Cognite will operate out of Station Houston and even has an internship program and partnership with Rice University. Overall, Laborie says the reception of the city has been positive.

"Houston went above and beyond," Laborie says. "The relationship with Rice has been very interesting because they are working closely with the Houston municipality to transform this image of Houston to get a stronger driver on innovation with the Innovation District, which spoke very loudly to us."

These partnerships are a crucial party of the company, Laborie says, and Cognite plans to work within Houston's innovation ecosystem to continue to push the envelope on innovative technologies.

"We have partnerships with large corporations, but we also see the importance to work with smaller companies to drive innovation — even if they aren't directly related," Laborie says.

Ad Placement 300x100

Ad Placement 300x600

CultureMap Emails are Awesome

Property Showcase

Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

View All Listings

INNOVATIONMAP EMAILS ARE AWESOME