Softeq Venture Studio's growing portfolio of startups in its accelerator work out of FUSE Workspace in City Centre. Image via fuseworkspace.com

A Houston early-stage accelerator has named 22 startups to its latest cohort.

Softeq Development Corp. has announced the companies joining the Softeq Venture Studio, the tech services company's accelerator program. A total of 22 companies have joined the program — hailing from the United Kingdom, Iceland, Mexico, Peru, and across the United States. This addition nearly doubles the program's portfolio, bringing the total number of startups to 49.

“This year has been a significant one for the Softeq Venture Fund and our portfolio companies. Due to the hard work of our team and the success achieved by previous founders, we’ve seen our investors and our entrepreneurs evolve to be more global than ever, and with more ambitious plans to revolutionize their industries," says Christopher A. Howard, founder and CEO of Softeq, in a news release. "We continue to attract world-class founders to Houston for our program that de-risks startups and investments."

Howard also announced a new limited partner. Houston entrepreneur Craig Ceccanti — co-founder of Pinot’s Palette and Rivalry Technologies — is the latest investor to join the $40 million Softeq Venture Fund, which is anticipated to close by the end of the year.

“Investors constantly search for opportunities that balance opportunity and risk, and ones that help us grow and maximize returns while maintaining a measure of stability and diversification,” says Ceccanti in the release. “Joining the Softeq Venture Fund is an exciting opportunity because it provides a de-risked investment opportunity plus the ability to participate in a hands-on fashion in Houston within these high-growth industries.”

The trend among the new cohort joining the program for the next three months includes health tech, sports tech, fintech, e0-commerce, Web 3.0, and more. Participating starups will have access to FUSE Workspace, as well as support and guidance from Softeq Venture Studio staff, Softeq engineers, local mentors, investors, and earlier cohort members.

“During our startup journey, we participated in leading technology accelerator Y Combinator. Later on, we realized through our users’ feedback we needed to improve our product with additional technology expertise and support to reach our full potential,” says Gerardo Briones, founder and CEO of new cohort startup Pagaloop of Mexico City. “That’s why we chose to participate in the Softeq Venture Studio. Softeq engineers have experience building enterprise-grade applications that scale up. We also get more opportunities to meet investors to bring our product to all of Latin America.”

The complete list of the new cohort of the Softeq Venture Fund, according to the news release, includes the following companies:

  • Adkaddy gets brands out of your email and into a powerful brand management tool. From discovery to promotions, shipping and receipts, this is digital commerce your way.
  • Allkind is benefiting reproductive healthcare globally by innovating fertility matching, empowering personal goals & improving modern family building.
  • atease is where 133 million government and military employees with strict rental requirements find approved, affordable, and reimbursable lodging options.
  • Boxes provides convenient, space-efficient, highly measurable, sampling and trial vending technology for premium CPG companies looking to reach customers where they shop and live.
  • Hapi is a stock trading platform with no minimums and no commissions focused on consumers in Latin America.
  • HelloDoctor puts qualified, responsive, and affordable doctors on the screens of 89 million cell phones of patients in Mexico. Healthcare just got better in Latin America.
  • Hightag is an automated media capture and delivery system that helps mountain bikers, skiers, and other action sport athletes capture and share their greatest moments.
  • IncentiFind is the nation’s go-to database of green building incentives, transforming U.S. real estate through $70 billion in incentives.
  • JamFeed aggregates artists' social media and music streaming content into an automated no-code website where artists can control their brand, their business, and their relationship with fans in one platform in less than 5 minutes.
  • Lesson Squad helps brands turn their customers into loyal users by creating a branded hub where customers can take lessons, enter competitions, and discover products.
  • LVED is an easy to use expert guided platform that provides everything families need to plan, organize, legally document end of life wishes, and memorialize loved ones.
  • Mesada is a digital remittance company that is utilizes blockchain technology to offer fast, efficient, and easy money transfers throughout the Latin American region.
  • Motusi is a whole-body wearable with AI to generate deeper insights related to movement quality and injury insights to help athletes progress in their performance or recovery.
  • MyShoots is an app for shooting sports organizations to connect with and market to their clients more efficiently, while allowing field-sports brands to connect with their customers.
  • Pagaloop is a fintech company that allows Latin American businesses more control over their cash flow when performing B2B transactions.
  • RESCUNOMICS offers a mobile app that helps save lives by expediting rescuer protocols and providing visibility into building floor plans and more.
  • sEATz connects fans to concessions and merchandise for in-seat delivery or pick-up reducing concession lines, increasing throughput, improving sales, and driving fan satisfaction.
  • SpecsX is transforming eye care into a virtual care model reducing costs, inconvenience for patients and providers, and giving everyone access to perfect vision.
  • Struttur Sports is an NFT platform where athletes share their experiences by connecting and combining digital and In Real Life events to create the deep interactions sports fans crave.
  • Svarmi is a digital platform that defines and prioritizes areas where business and progress influence nature providing meaningful, insightful metrics and proof of regulatory compliance.
  • SynvergySvn digitizes the movements of athletes with integrated wearables like the J-Sleeve so players, coaches, and trainers can diagnose muscle memory and improve repeat performance.
  • WulfTech protects and preserves the health of high-value K9 working dogs through smart wearable technology for government agencies, the military, and first responders.

The Softeq Venture Studio announced its inaugural cohort a year ago, and the fund was launched earlier this year. In August, Softeq expanded to New Hampshire to reach more startups and entrepreneurs.

Through a partnership with New Hampshire investors, Softeq has expanded its venture studio out of state. Image via hrknsscowork.com

Houston tech company's venture studio secures $5M investment, expands out of state

investing in investors

A Houston tech services company has announced fresh funding and a new location for its venture studio focused on growing startups.

Softeq Development Corp. announced an additional commitment of $5 million to the Softeq Venture Fund. With the investment, Softeq has a new partnership that will work toward creating a satellite venture studio in New Hampshire with local investors. Launch New Hampshire will leverage the Softeq Venture Studio platform to back qualified startups from within and outside New Hampshire, according to a news release from Softeq.

“It’s a great time to invest in startup companies, and we saw an opportunity to bridge the gap between the growing innovation community here in Houston and the untapped investment community in New Hampshire,” says Christopher A. Howard, founder and CEO of Softeq, in the release. “We’re excited about this partnership because it provides the Softeq Venture Studio with a source of high-quality startups while also fostering the innovation ecosystem in New Hampshire and New England.”

The Softeq Venture Studio announced its inaugural cohort last year, launching to act as an investor and accelerator program that provides mentors, resources, and workspaces for promising tech startups. This is the first expansion of the program and the latest investment into the Softeq Venture Fund, which has raised over $25 million of its $40 million goal.

Michael and Jamie Simchik, New Hampshire real estate developers, and Terry Anderton, an experienced technology entrepreneur, are the founders of Launch NH. The satellite cohort will work out of HRKNSScowork in Concord, New Hampshire.

“New Hampshire has been slow to adopt an innovation ecosystem, but with nearby Boston enjoying continued startup successes, we have the unique opportunity to leverage what is happening in Massachusetts, as well as in Vermont and Maine,” says Simchik, founder and CEO of HRKNSScowork. “By working with Softeq, we want to help build the innovation community statewide and drive broad-based startup activity in the region, similar to what Softeq has accomplished in its Houston headquarters.”

Anderton founded Wagz, which was recently acquired, an early participant in the Softeq accelerator program. Through his experience with Softeq, the company says he wanted to help bring the program other startups in the region.

The Softeq Venture Studio has made investments into 27 startups from across the globe since it launched in 2021. Over the next three years, per the release, Softeq intends to invest in 40 companies each year, including at least 12 via Launch NH.

This week's roundup of Houston innovators includes John "JR" Reale of the TMC, Maria Burgos of Trendy Seconds, and Christopher Howard of Softeq. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from venture funding to startup acceleration — recently making headlines in Houston innovation.


John "JR" Reale, executive in residence at Texas Medical Center Innovation and managing director of Integr8d Capital

John "JR" Reale joined the Houston Innovators Podcast for a special two-part series. Photo courtesy of TMC

John "JR" Reale has seen the evolution of Houston's innovation ecosystem from day one. Recently, he joined InnovationMap for a two-part series on the Houston Innovators Podcast to discuss the city's evolution as a tech and startup hub as well as what he's up to nowadays — leading venture activity at the Texas Medical Center Innovation and within his own firm.

"One of the most important moments for Houston was when we got kicked in the teeth with the Amazon HQ2 bid," he says on the show. "Amazon came back with the shortlist of the 20 cities in North America — and Houston isn't on it. I remember being excited. It was arguably the most innovative company in the world saying 'no thank you.'"

Flash forward, and Houston's a different ecosystem — still with a ways to go. Click here to stream part one and part two of the series.

Maria Burgos, founder of Trendy Seconds

A Houston innovator found second-hand shopping time consuming. So, she designed a better experience. Image courtesy of Trendy Seconds

After donating her items to a local church, Maria Burgos sought to be more sustainable and decided to try secondhand shopping.

“The good news was that I had so many options, new with tags, great conditions…the bad news was that it was so much that I ended up being frustrated because I didn't find what I liked,” she tells InnovationMap. “I had to spend hours of my time scrolling thousands of items, dozens of filters, multiple platforms."

She asked herself why there wasn’t a website where she could find items in one place. “That was the genesis of Trendy Seconds,” she shares. Click here to read more.

Christopher Howard, founder and CEO of Softeq

Chris Howard, CEO and founder of SofteqA Houston software company has announced its new venture fund. Photo courtesy of Softeq

Houston-based Softeq Development Corp. announced its third group of early-stage startups to join the Softeq Venture Studio, which is geared at helping its resident startups quickly develop their technology and build their businesses. With 14 startups, the summer 2022 cohort is the largest yet and brings the total portfolio to 27 companies. Additionally, the $40 million Softeq Venture Fund welcomed Royal Eagle Capital Partners, a Houston-based investment firm, as a limited partner with its $3 million commitment.

“We are thrilled to see how much the Softeq Venture Studio has grown since 2021,” says Christopher A. Howard, founder and CEO of Softeq, in a news release. “We’re also pleased to welcome Royal Eagle Capital Partners as an investment partner in our Venture Fund, which allowed us to achieve more than 50 percent of our funding goal in just five months. We look forward to building on this partnership and growing Softeq in North America, Latin America, and beyond.”

Softeq is also celebrating a recent expansion into Latin America and staffing the new regional office with 30 engineers. The company has plans to grow to 150 employees in the region over the next year. Click here to read more.

A Houston software company has announced its new venture fund. Photo via Getty Images

Houston tech company launches $40M fund to invest in early-stage startups

money moves

A Houston company that recently launched an innovation studio to support startups has now announced that they are launching a new fund to take startup support to the next level.

Houston-based Softeq Development Corporation, a global full-stack development company, launched The Softeq Venture Fund, a $40 million venture fund to invest in seed and series A startup rounds. According to a news release, more than half the fund will be deployed to power the Softeq Venture Studio, Softeq's recently launched accelerator program.

“For generations, the state of Texas has been home to world-renowned tech companies who have greatly contributed to our regional success. As a local entrepreneur, advisor, and angel investor, it’s been my dream for many years to create a venture fund benefiting startups," says Christopher A. Howard, founder and CEO of Softeq, in the release. "I am proud to increase our support of the state’s early-stage tech community. Our investment fund is designed to attract tech visionaries from both inside and outside the state and grow innovative concepts in Houston."

Jumana Capital, a single-family office also based in Houston and founded in 2018, has made a "sizable investment" in the fund, per the release.

“The Softeq team has successfully engineered, developed, and launched technology solutions for enterprise and early-stage companies for 25 years. In partnership with Softeq, we are thrilled to play a role in the creation of their new fund and to support the entrepreneurs that come to Houston to develop cutting-edge technologies and build businesses,” says Chris Martin, managing director at Jumana Capital, in the release.

While the fund will mostly go into investing in and supporting studio companies, Softeq will also tap into the fund to "invest opportunistically."

In October, the company announced the six startups that make up the studio's inaugural cohort. The purpose of the studio was to identify startups with scalable solutions but that need guidance and support from Softeq and its network.

"Historically, most tech startups had a founder with development skills. However, we're now seeing more and more business people, doctors, and other professionals start companies, and they need a strong engineering partner to develop their products," Howard says in an October news release. "We take it several steps further with the Venture Studio providing technology business consulting, development services, and much-needed cash. We're a vested partner, so we also help secure follow-on funding for continued growth."

Applications are open for the spring 2022 cohort. More information and applications are available online.

Christopher A. Howard is the founder and CEO of Softeq. Photo courtesy of Softeq

The lab will launch virtually first, before moving into a physical space early next year. Photo via Getty Images

Houston software company to launch innovation lab for enterprise startups

new to hou

A Houston-based global software development company has teamed up to create an innovation lab that will launch virtually before moving into a physical space early next year.

Softeq Development Corporation announced the creation of the Softeq Innovation Lab in partnership with the Massachusetts Institute of Technology's Integrated Design and Management program and Massachusetts-based Boundless Technology. The lab is directed at helping enterprise companies collaborate on the technologies of tomorrow, according to a news release.

"At the Softeq Innovation Lab, we recognize the importance of developing an incubator that goes beyond innovation theatre and are rolling up our sleeves to achieve transformative disruption in enterprise companies," says Christopher A. Howard, Softeq founder and CEO, in the release.

"The first wave of disruption was based in Silicon Valley," he continues. "The second wave of disruption is occurring in industries central to Houston's economy such as energy, health care, and financial services. With technology rewriting the playbooks for these industries, Houston is the perfect venue for our Innovation Lab to enable companies to thrive in this new age of disruption."

First up for the lab is a series of Boundless Bootcamps, which aims to connect participants to corporate disruptors, including David Rose of Warby Parker and MIT Media Lab.

"The city of Houston is at the center of a powerful convergence between industry, innovation and proven intrapreneurs," says Chuck Goldman, principal at Boundless Technology, in the release. "The Softeq Innovation Lab brings together entrepreneurs, corporations and 20X innovators who have achieved ROI of at least 20X and built billion-dollar businesses."

In addition to having access to MIT, Boundless, and Softeq's global networks, the participants will also receive an MIT IDM Certification from the nation's top engineering, design, and business program.

"I'm thrilled to bring our leadership and human-centered design program to Houston to help intrapreneurs drive breakthrough growth in leading organizations" says Matt Kressy, founding director MIT IDM, in the release.

For additional information or to find out more about how to get involved please visit the Softeq Innovation Lab's website.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."