3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Chris George of Octopus EV, James Allison of MD Anderson, and Paul Wotton of RBL LLC. Photos courtesy

Editor's note: Every week, I introduce you to a handful of Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes a biotech leader, a Nobel laureate, and EV innovator.

Chris George, United States co-lead at Octopus Electric Vehicles

Chris George, United States co-lead at Octopus Electric Vehicles, joins the Houston Innovators Podcast. Photo courtesy of Octopus

Switching from a gas-powered car to an electric one can be a big change, but a Houston-based company has made things a lot easier for its customers.

Octopus Electric Vehicles US, a spinout of United Kingdom-based retail energy provider Octopus Energy, matches its users with their perfect EV lease and sets them up with smart electricity technology for at-home charging.

"We do a couple of really unique things that are not only first of its kind but really innovative," Octopus EV's US Co-Lead Chris George says on the Houston Innovators Podcast, pointing out specifically Octopus Energy's Intelligent Octopus, a smart feature for customers that automates energy usage to lower cost.

"We launched an Intelligent Octopus for EVs service. Instead of operating in a very narrow window — overnight — it operates dynamically," he continues. Read more.

James P. Allison, director of the James P. Allison Institute

MD Anderson's lab led by Nobel laureate James Allison has secured a $5 million donation. Photo courtesy of MD Anderson Cancer Center

The James P. Allison Institute at The University of Texas MD Anderson Cancer Center scored a $5 million gift at its second annual symposium.

On behalf of Mayor John Whitmire, Oct. 10, 2024 was named “James P. Allison Institute Day,” and it was also the day that the TMC3 Collaborative Building in the Texas Medical Center’s Helix Park greeted 900 attendees for the scientific symposium, entitled “Immunotherapy in Space and Time: The Tumor Microenvironment.”

“Spatial biology is a rapidly expanding field that offers tremendous new insights into immunobiology that were not possible just a few short years ago. Understanding how immune cells interact with their neighbors and with tumor cells in space and time will enable us to bring forward new strategies to improve immunotherapy outcomes,” says James P. Allison. “We are proud to host this annual symposium to advance the field, and we are extremely grateful for the support of the Wintermann Foundation to make new breakthroughs possible.” Read more.

Paul Wotton, managing partner of RBL LLC

Established to rapidly build companies based on Rice University's portfolio of over 100 patents, RBL LLC is Rice University's new biotech venture creation studio based in Texas Medical Center Helix Park. RBL comes on the heels of establishing the Rice Biotech Launch Pad, a biotech innovation accelerator that opened last year.

Paul Wotton, executive director of the Rice Biotech Launch Pad, co-founded RBL with his colleagues Omid Veiseh, Rice professor of bioengineering and faculty director of the Rice Biotech Launch Pad; Jacob Robinson, Rice professor of electrical and computer engineering; and Dr. Rima Chakrabarti, a physician scientist and venture capital investor with KdT Ventures.

“This is a pivotal moment for Houston and beyond,” Wotton, who serves as RBL’s managing partner, says in a news release from Rice. “Houston has rapidly emerged as a global life sciences powerhouse, blending cutting-edge research with early clinical applications at Rice and the city’s world-renowned hospital systems." Continue reading.

Chris George, United States co-lead at Octopus Electric Vehicles, joins the Houston Innovators Podcast. Photo courtesy of Octopus

Houston innovator drives EV adoption with unique approach to car leasing, smart tech

HOUSTON INNOVATORS PODCAST EPISODE 258

Switching from a gas-powered car to an electric one can be a big change, but a Houston-based company has made things a lot easier for its customers.

Octopus Electric Vehicles US, a spinout of United Kingdom-based retail energy provider Octopus Energy, matches its users with their perfect EV lease and sets them up with smart electricity technology for at-home charging.

"We do a couple of really unique things that are not only first of its kind but really innovative," Octopus EV's US Co-Lead Chris George says on the Houston Innovators Podcast, pointing out specifically Octopus Energy's Intelligent Octopus, a smart feature for customers that automates energy usage to lower cost.

"We launched an Intelligent Octopus for EVs service. Instead of operating in a very narrow window — overnight — it operates dynamically," he continues.


Pulling from the success of its British EV leasing business, Octopus EV helps Texans find their ideal car to lease from the available pre-owned EVs in the state. The process is hands on, George says, and he and his team are constantly working directly with customers to find them their right make, model, mileage, and more, then setting them up for free home charging with Octopus. All this for as low as $200 a month — perfect for both EV veterans and newbies alike.

"We serve a lot of people. What we're aiming to do is to drive adoption, and we're finding that for most people this is their first EV," George says, explaining that accessibility has been an issue for aspiring EV owners.

The company is rolling out a new process this week. In addition to providing its service in a match-making capacity, now Octopus EV will be showcasing EVs so that customers can browse, test drive, and really get to see what all they like before deciding on a car. George says this new process will be a bit of an experiment.

"We're gong to be showcasing inventory around Houston so customers can see the physical car, the lease price, test drive, and get the car you want," George says. "It's going to look and feel a little different from our current product, but it's going to serve customers just the same."

On the show, George, who previously led EV adoption-focused nonprofit Evolve Houston, shares a bit about the EV industry and what he's closely watching, including growth of charging stations, multifamily charging opportunities, battery technology for EVs and resilience, and perfecting messaging for new and returning customers.

"I'm always trying to think about where are the other things where we can unlock innovation, unlock ideas that help our industry and help Houstonians," George says.

This week's roundup of Houston innovators includes Ana Amicarella of EthosEnergy, John Arnold of Centaurus Capital, Chris George of Octopus Electric Vehicles, and the 2024 Houston Innovation Awards judges. Photos courtesy

3+ Houston innovators to know this week

who's who

Editor's note: Every week, I introduce you to a handful of Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes an energy leader, an electric vehicle expert, and more.

Ana Amicarella, CEO of EthosEnergy

Ana Amicarella, CEO of EthosEnergy, joins the Houston Innovators Podcast to discuss the company's growth amid the energy transition. Photo courtesy of EthosEnergy

For most of her career, Ana Amicarella has been the only person in the room who looks like her. But as CEO of Houston-based EthosEnergy, she's changing that.

"The energy sector for sure is highly dominated by men, but I think it's such an exciting environment," Amicarella says on the Houston Innovators Podcast. "What I try to do at every job that I go to is I try to increase representation — diverse representation and females in the company. And I measure that when I started and when I end. I want to be able to make a difference."

Amicarella joined EthosEnergy — which provides rotating equipment services and solutions to the power, oil and gas, and industrial markets — as CEO in 2019 a few years after it was in 2014 as a joint venture between John Wood Group PLC and Siemens Energy AG. Prior to her current role, she served in leadership roles at Aggreko an GE Oil and Gas. Read more.

John Arnold, founder of Centaurus Capital

A Houston company has raised funding from a local investor. Photo via Centaurus Capital

A Houston company has closed its series B extension at $25 million.

MetOx International, which develops and manufactures high-temperature superconducting (HTS) wire, announced it closed a $25 million series B extension. Houston-based Centaurus Capital, an energy-focused family office, and New System Ventures, a climate and energy transition-focused venture firm, led the round with participation from other investors.

"MetOx has developed a robust and highly scalable operation, and we are thrilled to partner with the Company as it enters this pivotal growth stage," says John Arnold, founder of Centaurus, in a news release. "The market for HTS is expanding at an unprecedented pace, with demand for HTS far outweighing supply. MetOx is poised to be the leading U.S. HTS producer, closing the supply gap and bringing dramatic capacity to high power innovations and applications. Their progress and potential are unmatched in the field, and we are proud to support their growth." Read more.

Chris George, United States co-lead at Octopus Electric Vehicles

Texas is positioned to be a great state for the EV industry, writes this expert. Photo via LinkedIn

As Texans continue to invest in electric vehicles, public charging needs to be able to meet an increased demand, according to Chris George, the United States co-lead at Octopus Electric Vehicles, who wrote a guest column for InnovationMap about the state's potential when it comes to EVs.

"As we look to the future of transport and energy, the synergy between NEVI and Tesla’s network should create a compelling narrative for those thinking about leasing an EV," he writes. "Combine that with exciting new battery tech and potential range improvements, fueled by West Texas wind and solar, Texas is positioned to be a great state for the EV industry." Read more.

2024 Houston Innovation Awards judges

Here's who's calling the shots for the 2024 Houston Innovation Awards. Photos courtesy

Ten Houstonians are in the hot seat for deciding the best companies and individuals in Houston's innovation ecosystem.

InnovationMap has announced its 2024 Houston Innovation Awards judging panel, which includes startup founders, nonprofit leaders, investors, corporate innovators, and more. In addition to the 10 judges, InnovationMap Editor Natalie Harms will serve as the editorial representative on the judging panel.

The selected judges will evaluate applications from the nearly 300 nominations that were submitted this year. The judges will be using their expertise to evaluate the nominees' applications, which are due to InnovationMap this week. Read more.

Texas is positioned to be a great state for the EV industry. Photo via Getty Images

How Texas is on the road to becoming a prime state for EVs, according to this expert

guest column

As Texans adopt electric vehicles, significant strides must be made to ensure public charging meets demand. Steps are being made under the National Electric Vehicle Infrastructure Formula Program to address such needs. With new developments promising to bolster the state's infrastructure, it’s only a matter of time until all EV owners will have access to reliable and fast charging options.

NEVI Funding in Texas

Texans will benefit from NEVI funding. This federal initiative is part of a broader effort to enhance EV adoption by providing drivers with a robust and reliable network of fast chargers, particularly along corridors, i.e., highways between Houston, Dallas, Austin, San Antonio, etc. To date, Texas has been busy installing 66 fast-charging ports along those key corridors with much more to come (Electrify News Site). There are multiple phases associated with NEVI, and the first 50 sites outlined by the Texas Electric Vehicle Infrastructure Plan have been completed.

Enhanced Accessibility and Convenience

One of the key aspects of the NEVI-funded stations is their strategic placement in areas previously underserved by existing charging networks. This focus not only addresses range anxiety but also ensures a minimum of four chargers per site with a reliability standard of 97 percent uptime. Such strategic deployment is crucial for supporting the widespread use of electric vehicles, especially in a state as vast as Texas (Electrify News Site).

NACS Compatibility and Adapters: Bridging the Gap

To further support all EV drivers, Tesla has opened their previously closed charging network. This network’s charging system is known as the North American Charging Standard, or NACS. This will allow for other brands to leverage the largest and most reliable charging network in Texas and beyond. Now, just about every manufacturer has opted in to the NACS charging ecosystem. This standard will undoubtedly result in more coverage for all EV drivers and a true standard for the industry. You can see the list of manufacturers that have adopted NACS thus far here.

If you already drive a non-Tesla EV, don’t worry. Many manufacturers have embarked upon developing an adapter for you such as Ford. If you drive a Tesla, your options will remain more or less the same. You’ll not need an adapter with future fast charging stations.

At the end of 2023, there were roughly 19,000 Tesla Superchargers and 15,000 from the entirety of the charging community. Tesla aims to add another 7,500 by the end of 2024 in addition to $7.5B from the federal government to support all other charging initiatives.

This move is particularly beneficial for Texas, where the distances between charging stations can be vast. By enabling access to Tesla's superchargers, drivers can embark on long road trips with the assurance that a fast and reliable charging option is never far away. This increased accessibility will likely spur greater EV adoption, as drivers gain confidence in the state's charging infrastructure.

Charging at Home

The concept of fueling and charging EVs at home offers an exciting paradigm shift. Drivers often have to wait for their cars to approach Empty “E” on their dashboard. Some take it all the way down to the red line (or below) while others begin searching for gas stations once they’ve reached a quarter tank.

With EVs however, the average Houstonian who drives ~30 miles a day now has the potential to begin their day with a full charge. Those who have access to home charging can plug their cars in when they get home from work and typically make up for their daily driving/commute with a standard power outlet which offers a customer anywhere from 30-40 miles of charger over a 12 hour period.

But let’s say you’re a super commuter - someone who drives 75 miles a day or more! Starting off with a full charge every day is almost a necessity, and a standard power outlet may not cut it. Luckily, Level 2 chargers exist and serve as an incredible time and money saver. Like the average commuter, a super commuter can simply plug in a level 2 charger, and the EV will be back to full by the time they wake the next morning (offering anywhere from 20-30 miles of charge per hour). Even those who drive 150+ miles a day can confidently use their EVs as a daily driver if they have a Level 2 charger at home.

Embracing the Future

As we look to the future of transport and energy, the synergy between NEVI and Tesla’s network should create a compelling narrative for those thinking about leasing an EV. Combine that with exciting new battery tech and potential range improvements, fueled by West Texas wind and solar, Texas is positioned to be a great state for the EV industry.

———

Chris George is the United States co-lead at Octopus Electric Vehicles.

This article originally ran on EnergyCapital.

A Houston company has announced a new service that will encourage electric vehicle use. Photo via Getty Images

Houston energy company announces new EV business arm

making moves

Houston-based energy retailer Octopus Energy U.S. is now getting its tentacles into the electric vehicle business.

Octopus Energy US on July 6 unveiled Octopus Electric Vehicles, whose first offering is EV Concierge. This new service will help customers lease an EV, and integrate smart charging and billing into their existing energy plan.

New and existing customers in Texas can apply for the beta leasing program at octoev.us. Employees of the program will help customers search for a new or used EV to lease, install an at-home EV charger, and adopt best practices for EV ownership.

“Interest in electric vehicles is at an all-time high. With Texas as the third-largest market for EVs and a global leader in energy, we will be positioned to help customers realize vehicle and energy savings all on one bill,” says Chris George, U.S. director of Octopus Electric Vehicles. “As fossil fuel continues to be impacted by inflation, it’s never made more sense to get an EV paired with smart charging to extract the lowest-priced energy from the grid.”

EV Concierge is paired with Intelligent Octopus, which lets customers access power when it is cheaper and greener while helping balance stability of power grid.

Octopus Electric Vehicles launched in 2018 in the United Kingdom, where parent company Octopus Energy Group is based. In the U.K., Octopus leases EVs, installs at-home chargers, provides EV tax breaks, and provides access to more than 250,000 public charging stations in Europe.

Customers of Octopus Electric Vehicles can lease 65 different EVs from 28 automotive brands.

“We’ve seen that consumers are looking for experts that can offer the full EV package to guide them through their journey,” says Fiona Howarth, CEO of Octopus Electric Vehicles. “With more EV models entering the market every month, and innovative tariffs like Intelligent Octopus making charging your car as easy as [charging] your phone, we only expect the transition to accelerate.”

The launch of EV Concierge comes just a year after Octopus Energy U.S. set up shop in Houston. Establishment of the Houston presence coincided with the company’s $5 million acquisition of Houston-based Evolve Energy.

Last month, Kraken Technologies, the software licensing arm of Octopus Energy Group, picked Houston for its U.S. headquarters.

Octopus Energy Group, valued at nearly $5 billion, entered the U.S. market in 2020. It supplies green energy to more than 3 million retail customers around the world.

From the potential for electric vehicle growth to the role of corporates, experts joined a panel to discuss the progress of Houston's low-carbon energy initiatives. Photo by Katya Horner

Overheard: Here's where Houston's low-carbon efforts stand, according to the experts

eavesdropping online

Houston is moving the needle on low-carbon initiatives, as one panel agreed at the Center for Houston's Future's Low-Carbon Energy Innovation Summit.

The annual event, which is taking place virtually this year, was broken up into two days. The first installment focused on low-carbon markets on October 8. This week on October 15, the virtual programming will cover Houston's energy ecosystem.

While the day of low-carbon programming zeroed in on specifics within the subject, one panel zoomed out to check in on Houston's progress. Brett Perlman, president and CEO for the center for Houston's Future, moderated the discussion, which featured five energy experts. Here are some highlights from the panel.

“We’ve identified 200 companies in Houston that we would call energy 2.0 companies — solar, wind, energy stories, and other energy and clean tech companies. So, there’s already a lot happening.”

— Bob Harvey, president and CEO of the Greater Houston Partnership.

“While innovation and the energy transition are not the same thing, they are close cousins. Innovation is about change and new businesses and how they work with incumbent businesses, so when you think about the transition, you have to include both of them.”

— Barbara Burger, Chevron's vice president of innovation and president of Chevron Technology Ventures.

“Hurricane Harvey was a point where so much changed. Everything I do in my job changed. We went from climate being talked about discretely to something we can’t not talk about. It’s in every conversation whether we like it or not.”

— Lara Cottingham, chief of staff and chief sustainability officer for the city of Houston.

“This is a global challenge, but Houston is a global leader. We really want to be hands on and tackle this to keep Houston in that leadership role.”

— Cottingham continues.

“Houston has the engineering expertise and experience doing energy at scale. Frankly, we need that set of expertise at the table.”

— Emily Reichert, CEO of Greentown Labs, which recently expanded to Houston.

“We’d like to see 30 percent of new vehicle sales be electric vehicles by 2030. I think we’ll get there much sooner.”

— Chris George, president and executive director of EVolve Houston.

“Houston is very important and significant because of our relation to the port. Whether it’s looking at hydrogen trucking for long haul trips or looking at reducing logistics cost for manufacturing and assembly, Houston has everything to offer.”

— George continues.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Property Showcase

Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

View All Listings