3 Houston innovators to know this week

Who's Who

From a former astronaut to growing software company leaders, here are three innovators to know. Courtesy photos

This week's set of innovators to know are familiar with pivoting careers. All three had successful careers — from energy finance to space exploration — before jumping into a new field. And each set of prior experience prepared them for what they are doing today.

Alex Colosivschi, founder and CEO of Currux

Courtesy of Currux

Alex Colosivschi had a successful career in energy finance before he started his company, Currux. He was walking in his Rice Village neighborhood when the idea came to him. He realized that despite the green surroundings, he was choked by the smell of engine exhaust.

"I started with thinking about the future of energy and how the industry will adapt to a world of electric, autonomous and shared mobility, and the need to reduce CO2 emissions," he says.

Tim Kopra, partner at Blue Bear Capital

Courtesy of Blue Bear Capital

It might not be easy to connect the dots between Tim Kopra's NASA career and his current role at Blue Bear Capital, but for Kopra, it makes perfect sense.

"On face value, it may sound like an odd match, taking someone with a tech and operational background and putting them in venture, but quite frankly it feels very familiar to me because my career has really been focused on working on complex technology and operations with very small teams," Kopra says. "It's not just a theoretical understanding of the technology, but understanding how to use the technology and how it works."

Stuart Morstead, co-founder and COO of Arundo Analytics

Courtesy of Arundo Analytics

Stuart Morstead spent the bulk of his career in consulting, so he knows the importance of understanding the needs an industry has. He co-founded Arundo Analytics to address the analytical needs energy companies have on a regular basis.

Morstead says that most industrial companies that encounter issues with operations such as equipment maintenance "lack the data science and software capabilities to drive value from insights into their daily operations."

Arundo is growing — both from a funding standpoint as well as through its staff. The Houston company has big plans for its 2019.

From tech innovators to recently funded startups and growing software companies, here's what you're reading this week. Pexels

5 top trending innovation stories in Houston this week

What You're Reading

Editor's note: The most read stories on InnovationMap this week cover a myriad of things — from tech innovators and Houston innovation events to recently funded startups and growing software companies. Here are the stories that you're reading.

3 Houston tech innovators to know this week

These three innovators are using their technology to provide solutions across industries. Courtesy photos

Innovation isn't always about being the first to create a technology. Sometimes, innovation is seeing the potential an existing technology has to impact a different industry. That's what all three of this week's innovators to know have done across industries. And, they are are only just getting started. Read the full story here.

5 Houston startups beginning 2019 with new capital

These five companies are starting 2019 out with some cash, and here's what they plan on doing with it. Getty Images

Finding growing Houston startups is as easy as following the money, and a few local companies are starting 2019 strong with a recent round of funding closed. InnovationMap has rounded up a few recent raises to highlight heading into the new year. Read the full story here.

Updated: 10 can't-miss innovation events for January

From enlightening talks to anniversary celebrations, here's where you need to be in January. Getty Images

Houston's innovation community is starting 2019 strong with plenty of business professional events. This story first published a few weeks ago, but has been updated to include new events. Read the full story here.

Houston software company looks to grow its workforce internationally

This growing Houston company is providing industrial industries with smart analytics. Getty Images

A Houston-based analytics-focused company is gearing up for growth in 2019 and plans to staff up its headquarters and remote offices abroad.

Arundo Analytics Inc. brings industrial companies — which sometimes are slow to adopt brand-new technology — into the world of machine learning and advanced analytics to help boost revenue, cut costs and reduce risks. Read the full story here.

Growing Houston cyber security company plans to hire

Houston-based Security Gate has grown 1,000 percent each year. Getty Images

Cyber security is constantly evolving, and, while information hacks are always a concern, worst-case scenarios could even be life threatening.

Houston-based startup, Security Gate, is addressing all of types of cyber security threats, says Ted Gutierrez, an Army special forces vet and co-founder and CEO of the company. Read the full story here.

It might not be surprising to discover that the energy capital of the world is a hub for energy startups. Getty Images

5 emerging energy tech companies in Houston revolutionizing the industry

The Future is Now

If you thought Houston's wildcatter days were exciting, just you wait. Houston has an emerging ecosystem of tech startups across industries — from facial recognition devices used at event check in to a drone controller that mimics movement in space.

A somewhat obvious space for Houston entrepreneurs is oil and gas. While the energy industry might have a reputation of being slow to adapt new technologies, these five Houston startups are developing the future of the industry — one device at a time.

Future Sight AR

Lori-Lee Emshey's Future Sight AR is revolutionizing antiquated construction tools using augmented reality. Courtesy of Future Sight AR

Working on an oil and gas construction site is like constructing a really large puzzle — one that, if constructed incorrectly, could have dangerous and costly consequences. On her first job in the industry, Lori-Lee Emshey was required to move through the site with a pen and a clipboard to mark down any issues or problems, only to later log that information into a computer. It was a slow process, and she felt frustrated by that.

"I was really shocked at how much work they were doing with such little technology," Emshey says. "I thought, 'there's so much room for innovation here.'"

She created Future Sight AR that uses artificial reality technologies on a smart device so that technicians can instantly see instructions and solutions for the hardware they are constructing on the site. Read more about Future Sight AR here.

Nesh

Nesh's digital assistant technology wants to make industry information more easily accessible for energy professionals. Photo courtesy of Thomas Miller/Breitling Energy

Access to information is endless in the digital age, but Sidd Gupta wanted to create a digital assistant that specifically focused on the energy industry. Nesh is an information bot that users can chat questions to. Think: Siri or Alexa, but with an engineering degree.

"We created Nesh as something super-simple to use," Gupta says. "There's no learning curve, no technical knowledge required, you just need to speak plain English."

Nesh has the potential to change productivity and hiring requirements in various energy companies. Read more about Nesh here.

Cemvita Factory

The Karimi siblings have created a way to synthetically convert CO2 into glucose, and they are targeting the energy and aerospace industries for their technology. Courtesy of Cemvita Factory

Energy companies are getting more and more pressure to create a sustainable solution for the carbon dioxide refineries produce on a daily basis. Houston-based Cemvita Factory has a solution. The company has a patented technology that can convert CO2 into glucose — just like plants do in the photosynthesis process.

"We go to these companies and say, 'What do you want to convert CO2 into?,'" Moji Karimi, co-founder of Cemvita, says. "Then, we do a quick pilot in six months in our lab, and we show them the metrics. They decide if they want to scale it up."

The company also has big plans for making an impact on the aerospace industry too. Read more about Cemvita here.

NatGasHub.com

Jay Bhatty looked at how pipeline data reached traders and thought of a better way. Getty Images

Information around natural gas pipelines — such as whether a pipeline has capacity issues that could trigger a spike in prices — has, for years, been scattered across the web. Now, Houston-based NatGasHub.com aggregates pipeline data from dozens upon dozens of websites.

Jay Bhatty, a veteran of the natural-gas-trading business, founded the Houston-based NatGasHub.com platform, which runs on cloud-based software, launched in late 2017. The company is already profitable and hasn't taken any outside funding. Read more about NatGasHub.com here.

Arundo Analytics

This growing Houston company is providing industrial industries with smart analytics. Courtesy of Arundo

While information can be slow and siloed between energy companies, energy professionals come across the same problem within their own organization. Arundo Analytics is developing software to help connect the dots within an energy company's operations.

Stuart Morstead, co-founder and chief operating officer of Arundo, says that most industrial companies that encounter issues with operations such as equipment maintenance "lack the data science and software capabilities to drive value from insights into their daily operations." Read more about Arundo Analytics here.

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Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

     
  • $1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
  • $922 million for the University of Houston System
  • $167 million for Texas Southern University
  • $10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

     
  • Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
  • Created the Lake Houston Dredging and Maintenance District
  • Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.

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