treating addiction

Houston med-tech companies partner on wearable device for opioid withdrawal

A new medical device created in Houston is revolutionizing opioid withdrawal treatment. Photo via sparkbiomedical.com

Houston-based Spark Biomedical has created a revolutionary wearable device that provides unprecedented levels of opioid withdrawal relief.

The device known as the Sparrow Therapy System is worn over the ear for five to seven days and sends mild electrical signals to trigger cranial nerves that sit near the skin's surface.

Once activated, the nerves release endorphins that the body has stopped producing on its own during opioid use. The endorphins satisfy the opioid receptors and in turn reduce or prevent the intense symptoms that often come along with opioid withdrawal. According to Spark BioMed CEO Daniel Powell, the technology also helps patients better control their "flight or fight mechanisms," allowing them to make clearer, more logical decisions as they come off of the drug.

"If you ask 100 people who've gone through opioid withdrawal, I would bet 99 of them will tell you they thought they were going to die," Powell says. "Giving them the ability to manage that is huge. It's the first step towards addiction recovery. It's not solving the addiction, but it is an absolute barrier to move forward."

The product was approved by the FDA in January of 2020, after clinical trials showed that the Sparrow could meaningfully reduce withdrawal symptoms in the first hour of use. According to Powell, roughly a third of patients in the trial were completely out of withdrawal and patients' Clinical Opioid Withdrawal Scales scores reduced by more than 53 percent across the board.

Spark, which won Venture Houston's inaugural pitch competition earlier this year, partnered with Houston-based Velentium (which also happened to grow 93 percent last year after partnering with General Motors on Project V) to bring the product from concept to commercial physician prescribed product. "We needed a more sophisticated design house to help us finish it," Powell says.

The up-and-comers were connected through one of Spark's investors. Powell, in a previous career, had also sold a neurostimulator that Velentium CTO Randy Armstrong had invented.

"You're seeing more and more Houston centric medical innovation than we've ever seen before," says Velentium CEO Dan Purvis. "And the cool thing about that is there ends up being a camaraderie amongst entrepreneurs, medical researchers and scientists."

And though the release of Sparrow marks a huge milestone, neither Spark of Velentium are stopping there. Moving forward, Spark aims to conduct a massive study on how a similar technology, dubbed the Roo, can aid infants born to opioid-dependent mothers wean from the drug.

The company also aims to create a next generation Sparrow with the help of Velentium, and will look at long-term uses of the product. Powell says that Spark will look to determine if the product can prevent relapses and help to cure addiction when worn daily or regularly.

"Our big, crazy, ambitious goal is can we actually help people recover from addiction," Powell says. "We're really not addressing psychology, that's going to be in cognitive behavioral therapy. But if we can remove the neurological results of drug use, we think we can make at least start to stack the deck in the favor of the patient versus having the deck stacked completely against them all the time."

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Building Houston

 
 

Houston Tech Rodeo returns with 2023 programing across space, health, emerging tech, and more. Image via houstontechrodeo.com

Houston Tech Rodeo returns this year — and the lineup of panels and networking opportunities has been released online.

The four-day summit was originally introduced in 2020 by Houston Exponential to shine a spotlight on Houston's tech and startup ecosystem. Last year, HX changed ownership, converted into a for-profit business, and named Natara Branch as the new CEO. With the new ownership comes a new era for HTR — complete with AI-generated media, a goal for a record-breaking finale event with CodeLaunch, and more.

"The biggest theme of Tech Rodeo this year is around being aware," Branch tells InnovationMap. "We want entrepreneurs to know what resources are out there, that they are supported, and that there are all these entities out here that are conducting themselves in a manner that is really centered around supporting them."

"We hope that when entrepreneurs and startups walk away from Tech Rodeo this year, it will really feel to them like there's more momentum in this city than there has been in the past so that we can be a top-tier startup destination," she continues.

This year's schedule is divided across a few themes and all events are being held in the Houston Innovation District in Midtown.

  • Monday, February 27: Space Tech at the Ion
  • Tuesday, February 28: GlobalMindset at HCC Central Campus and EnergyTech at Greentown Labs
  • Wednesday, March 1: BioEconomy at TMC Innovation and EmergingTech at The Cannon - Downtown
  • Thursday, March 2: Townhall and CodeLaunchFinale at Sesh Coworking and 713 Music Hall
The week's events will attract founders, investors, startup development organizers, and more. When HTR launched its free tickets online, Branch says they received around 800 registrants in one day. At the center of everything HX does is the Houston founders, Branch says.
"It was supper important to us to make sure that entrepreneurs have access," she says. "It's free to entrepreneurs — they are number one in who should attend."

More information and registration is available at houstontechrodeo.com.

Head to houstontechrodeo.com for up-to-date schedule information. Graphic courtesy of HX

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