A local church deploying handwashing stations across town was one of this year's top social impact stories on InnovationMap. Photo by Nijalon Dunn

Editor's note: As 2020 comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. InnovationMap's most read articles regarding social impact innovation include a new incubator program from impactful startups, a church providing handwashing stations for Houston's homeless, and more.

Local organization creates handwashing stations for Houston's homeless communities

A local church is deploying handwashing stations across town. Photo by Nijalon Dunn

When the coronavirus forced the closure of restaurants, stores, and community centers, it disproportionally affected the health of a population of people: The homeless.

Homeless individuals are acutely vulnerable amid the public health and hygiene concerns due to the coronavirus pandemic, says Houstonian Nijalon Dunn. These communities of people have been left without immediate access to soap and clean water, especially with the closure of local businesses whose restrooms sometimes served as individuals' only sources of clean water.

"[Local businesses are] where people were able to use the restroom, wash their hands and have access to soap and water," Dunn says. "Take public restrooms away, now you have an increase in public urination and people using the restroom outside. Not only that, but people aren't washing their hands because of a lack of education and awareness about social distancing and hygiene practices."

Observing this effect of the virus, a group of Houstonians pulled together their skills and resources to provide handwashing stations across the city for Houston's homeless population.

Rise Houston Church, a local organization servicing inner-city Houston, is behind the initiative. Eager to help the community during the coronavirus pandemic, Rise Houston's pastor Stan DePue proposed the idea of building and distributing handwashing stations that would provide clean water and soap to homeless communities. Click here to continue reading.

Houston area high school students develop innovations to help  in coronavirus crisis response

Teens at a local school took initiative to create entrepreneurial solutions amid the COVID-19 crisis. Photo courtesy of The Village School

Some Houston-area high school students have stepped up to help their community during the outbreak of the novel coronavirus. The students have worked on two separate teams to create an intubation box to reduce the spread of COVID-19 from patients to healthcare workers and SpeeDelivery, an app that delivers food for at-risk individuals.

The students from The Village School in the Energy Corridor, known for its unique and enriching IB diploma, are getting support from school educators. The two projects grew naturally from the interests of the high school juniors, who wanted to do anything that could help others during this crisis.

"Our teachers have been very supportive have really enjoyed having the opportunity to see the students," says TeKedra Pierre, director of experiential learning at The Village School. "It's hard enough to teach virtually but with platforms like Zoom, Google classroom, and other platforms that they have been using to communicate and make sure that our students are still doing well."

The students created the intubation box out of clear plastic with two areas of access so that doctors can put their hands through it and intubate a patient who needs a ventilator. The box prevents exposure to the virus which can be passed in microdroplets from patients to healthcare workers. Click here to continue reading.

Houston nonprofit introduces new startup incubator ahead of impact-focused innovation week

Grace Rodriguez, CEO and executive director of Impact Hub Houston, introduced a new program for startups. Courtesy of Grace Rodriguez

Impact Hub Houston — the local chapter of a nonprofit focused on supporting startups in the social impact space — has a lot on its plate this month.

Not only is next week The Houston Innovation Summit — the fourth annual week of entrepreneurship programming — as well as the second annual Climathon, but the organization has also just launched a new business incubator program.

Accelerate is a program that Impact Hub has offered across 17 international markets. Houston's new chapter already has a few Houston startups involved — including Potentia Workforce and McMac CX. Structured as an ongoing accelerator with mentorship, education, and support, the program is currently accepting new members.

"We actually sit down with each new Accelerate member and then go through a diagnostic interview to help them understand what stage they're at," says Grace Rodriquez, CEO and executive director of Houston Impact Hub. "And then we create a development strategy with them."

Whether the Accelerate member needs one-on-one mentorship, specialized education, or more, the program match makes each member's needs. EY is a network partner and — since everything is virtual — member companies have access to international experts through Impact Hub and its partners' networks.

"The ideal entrepreneur for the Accelerate membership is somebody who has already developed a solution — at least an MVP — for their social venture, whether it's a product or a service," Rodriguez says. Click here to continue reading.

Growing Houston thrift startup aims to impact the unsustainability of the fashion industry

Houston-based Goodfair takes clothing that would otherwise end up in landfills and turns it into a "mystery shopping" thrift experience. Photo courtesy of Goodfair

A Houston-based online retailer for second-hand clothing is quickly growing, aiming to make "No New Things" the mantra of the fashion world.

As the popularity of "Fast Fashion," or cheap clothing produced rapidly by mass-market retailers, begins to decline, brands are refocusing on upcycled, recycled, and sustainable clothing — and Goodfair has bet its business plan on this movement.

"I realized that there was too much stuff out there," says Topper Luciani, founder and CEO of Goodfair, "and there is an environmental crisis being caused by the clothing industry. They're manufacturing so many items, they're using slave labor, they're pumping dyes and other chemicals into rivers. It's absolutely wild."

The fashion industry contributes 10 percent of the world's carbon emissions, is the second-largest user of the earth's water supply, and pollutes the oceans with microplastics according to a report from Business Insider in October 2019. Additionally, the outlet reports that 85 percent of all textiles go to the dump every year.

"Still, we have an enormous demand for these clothes that are being thrown away and that demand is just being filled by more cheap new clothes at malls and things like that, instead of reintroducing second-hand clothes," says Luciani. "I've been working really hard on creating a way to make a frictionless process for reintroducing those clothes." Click here to continue reading.

New program at Rice University to educate corporate leaders on innovation

A new program within Rice University's Executive Education school will foster education for corporate innovation. Photo courtesy of Rice

As important as it is to foster innovation among startups, there's another side of the equation that needs to be addressed, and a new program at Rice University plans to do exactly that.

Executive Education at Rice University's Jones Graduate School of Business, which creates peer-based learning and professional programs for business leaders, has created a new program called Corporate Innovation. The program came about as Executive Education, which has existed since the '70s, has evolved over the past few years to create courses and programs that equip business leaders with key management tools in a holistic way.

"We realized we need to open the innovation box," says Zoran Perunovic, director of Executive Education and is also a member of the Innovation Corridor committee and a mentor at TMCx.

The program, which is open for registration and will take place September 28-30, will flip the script on how innovation is normally discussed and observed and instead take a holistic approach to innovation in a corporate setting.

"In the innovation space, you have two lines — one is the entrepreneurial and the other is happening in large, established organizations," Perunovic tells InnovationMap. "The mechanisms of innovation within in those companies are different than the entrepreneurial." Click here to continue reading.

A new program within Rice University's Executive Education school will foster education for corporate innovation. Photo courtesy of Rice

New program at Rice University to educate corporate leaders on innovation

tables have turned

As important as it is to foster innovation among startups, there's another side of the equation that needs to be addressed, and a new program at Rice University plans to do exactly that.

Executive Education at Rice University's Jones Graduate School of Business, which creates peer-based learning and professional programs for business leaders, has created a new program called Corporate Innovation. The program came about as Executive Education, which has existed since the '70s, has evolved over the past few years to create courses and programs that equip business leaders with key management tools in a holistic way.

"We realized we need to open the innovation box," says Zoran Perunovic, director of Executive Education and is also a member of the Innovation Corridor committee and a mentor at TMCx.

The program, which is open for registration and will take place September 28-30, will flip the script on how innovation is normally discussed and observed and instead take a holistic approach to innovation in a corporate setting.

"In the innovation space, you have two lines — one is the entrepreneurial and the other is happening in large, established organizations," Perunovic tells InnovationMap. "The mechanisms of innovation within in those companies are different than the entrepreneurial."

The course's professor is Jing Zhou, Mary Gibbs Jones Professor of Management and Psychology – Organizational Behavior, and she says that when people think "innovation" they think of startups or technology. However, when it comes to innovation at the corporate level, it's so much more than that.

"In the past, we think about corporate innovation, we think about technological advancements. Because we have so many world-class organizations in Houston, we feel like we are doing a good job," Zhou says.

"Innovation definitely includes technology, but it also involves new business models, new way of meeting customers, new work processes — everything we do in a large corporation, there's always a better way of doing it. That's our definition of our corporate innovation."

Zoran Perunovic (left) anf Jing Zhou created the Corporate Innovation program housed in Rice's Executive Education department. Photos courtesy of Rice

Zhou and Perunovic designed the program to target business professionals from all areas of the corporate world.

"People, managers, professionals, executives in all functional areas of business can benefit from this program," Zhou says. "We don't teach to just one function area. We teach the fundamental principles of how to drive innovation and broaden the cognitive space."

Perunovic concurs with his colleague and adds that, "everyone is relevant — that's the future of innovation." Another aspect of the program that's forward thinking is the idea of cross-industry innovation collaboration.

"In all our programs, especially this one, we are not encouraging members from one type of industry to join. We want diversity of industry," Perunovic says.

The program has an advisory board comprised of business leaders in Houston. The program's board is made up of:

  • Tanya Acevedo, chief technology officer of Houston Airport System
  • Barbara Burger, vice president of innovation at Chevron and president of Chevron Technology Ventures
  • Gareth Burton, vice president of technology at American Bureau of Shipping
  • David Hatrick, vice president of innovation at Huntsman Advanced Materials
  • Roberta L. Schwartz, executive vice president and chief innovation officer at Houston Methodist

Industry, position, and company notwithstanding, the program has value across the board in Houston, now more than ever.

"Innovation is no longer optional for large organizations," Zhou says. "It's required in whatever you do, and whatever space you're competing in."

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”