3 Houston innovators to know this week

Who's who

This week's innovators to know represents a homecoming, an accelerator launch, and a call for tech education. Courtesy photos

This week's innovators to know span across industries — from sports tech to education, but they are all fighting for something here in Houston. Here's what they are focused on bringing to the Houston innovation ecosystem.

Mike T. Brown, founder of Win-Win

Courtesy of Win-Win

Mike T. Brown decided to move his Silicon Valley sports tech platform that gamifies charitable donations to his hometown of Houston. Win-Win, which launched in 2016 and since raised $1.2 million in funding, is ready to scale and launch full-scale during the 2019 NFL season.

"I couldn't be more excited about returning to Houston to become a part of the city's tech revolution," says Brown in the release. "After visiting The Cannon, I immediately felt the energy and have witnessed their commitment to pushing Houston's tech startup movement. I can't wait to get fully plugged into the city's ecosystem, to start hiring local talent and raising money from local investors." Read more about Brown and Win-Win here.

Yvette Casares Willis, director of strategic partnerships for MassChallenge Texas

Courtesy of MassChallenge Texas

Yvette Casares Willis has been working to put Houston on the map for MassChallenge Texas, and her work is finally coming to fruition. The organization opened applications for its inaugural cohort last week. As excited as she is to work with the cohort, Willis is looking forward to what it means for the program to arrive in Houston and help to connect the dots across the city's innovation ecosystem.

"I'm excited about what Houston has to offer," says Willis, who is the director of partnerships for the organization. "We have everything we could possibly provide in this ecosystem to be amazing, as long as we all work together. If we can all collaborate and if we all have the same mission, we can really make a difference in Houston." Read more about Willis and MassChallenge Texas here.

TeKedra Pierre, internship coordinator at The Village School

Courtesy of The Village School

Tekedra Pierre's job is to help students be aware of real-life needs in the workforce through internship programs. And what's extremely clear to Pierre is the need for more professionals in tech — specifically the cybersecurity space. She wrote a piece for InnovationMap on the subject.

"Employers struggle to keep employees up to speed on the latest technologies and skill sets needed to succeed and thrive in the rapidly changing and evolving business landscape," she writes. "To remain competitive, Houston businesses must attract qualified workers to fill these positions that range from cybersecurity to industrial technology, engineering and medicine. And the earlier we can reach them, the better." Read Pierre's piece here.

Yvette Casares Willis leads partnerships for MassChallenge Texas. Courtesy of MassChallenge

Accelerator program executive to connect the dots within Houston's innovation ecosystem

Featured Innovator

For Yvette Casares Willis, Houston already has what it takes to be a strong innovation ecosystem. Now, it's about working together to get the city where it needs to be, and MassChallenge hopes to do that with its new chapter in Houston.

MassChallenge Texas announced its new Houston program in January. Applications for the inaugural cohort will be officially open as of tonight's launch party for the program. The organization, which has locations around the world, looks for early stage startups that haven't raised more than $500,000 in equity-based funding and have generated less than $1 million in revenue over the past year. The cohort will support 25 startups with free GreenStreet office space, mentorship, investment opportunities, and more, all the while taking no equity in the companies.

Willis has been the organization's boots on the ground in Houston, since MassChallenge Texas is run out of Austin. She spoke with InnovationMap about what MassChallenge's Houston program means to her and the city.

InnovationMap: Why did the city need something like this?

Yvette Casares Willis: We're a little unique to what Houston already has. Houston has a lot of great organizations, but MassChallenge is unique in the fact that we're industry agnostic, we're a nonprofit, and we offer a different business model to be added into the local ecosystem.

IM: Having worked in Houston, what do you feel you bring to the table for MassChallenge?

YCW: My role covers the entire state, but I have been boots on the ground for MassChallenge in Houston and it's been exciting to bring this to where I'm from. I have over 20 years in the Houston market in the corporate environment — my background is in professional sports and entertainment.

IM: As the director of partnerships for MassChallenge, what have you been able to accomplish?

YCW: In the last 10 months, I've been able to meet with several community and corporate partners to talk about MassChallenge. I've seen a lot of excitement. We're working on collaborating, so that when we do have our cohort, we can provide them with the best opportunities to partner with the community and corporations."

IM: What are you most excited about for Houston's MassChallenge program?

YCW: I feel like Houston has all of the best ingredients to be an amazing ecosystem. MassChallenge is going to play a big part of bridging all of the different organizations together. I see that everything is here, but it needs to come together, and I think MassChallenge is really good at doing that wherever they are.

IM: What's next for MassChallenge?

YCW: In my role, when I talk to other organizations, I see a lot of interest between collaborations between Houston and other cities in Texas, but I also see a lot of excitement globally. Houston's a global city and a lot of people are excited about the network MassChallenge has around the world.

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Portions of this interview have been edited.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

New accelerator joins the Ion and more Houston innovation news to know

Trending News

Editor's note: The Houston innovation scene is buzzing with big news this month, from a new accelerator joining the fold at the Ion to pre-IPO funding and national expansion plans. Below are the five most-read InnovationMap stories from Feb. 1-15, 2026:

New accelerator for AI startups to launch at Houston's Ion this spring

The new AI Native Dual-Use Sports, Health & Wellness Accelerator is expected to launch in March. Photo courtesy of the Ion

The Collectiv Foundation and Rice University have established a sports, health and wellness startup accelerator at the Ion District’s Collectiv, a sports-focused venture capital platform. The AI Native Dual-Use Sports, Health & Wellness Accelerator is scheduled to formally launch in March. Continue reading.

10+ can't-miss Houston business and innovation events in February

From recurring monthly favorites to the return of annual celebrations and summits, here's what not to miss in February. Photo courtesy the Ion.

February may be a short month, but its event calendar isn’t. From recurring monthly favorites to the return of annual celebrations and summits, here are the Houston business and innovation events not to miss — and how to register. Continue reading.

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