The Lone Star State's mix of rural and urban settings — and other factors — has set it up for success as the economy reels from the COVID-19 pandemic. Photo by gguy44/Getty Images

A new study has found that businesses in Texas are in a good position to weather the storm that is the COVID-19 pandemic and subsequent economic challenges.

The FitSmallBusiness.com ranking factored in various metrics from overall financial health and emergency reserves to even how consumers feel about their state's ability to bounce back. The researchers weighted five metrics: Economic and financial Health (20 percent); least economic stressors (25 percent); emergency reserves and relief (25 percent); COVID-19 rates and health care infrastructure (20 percent); and consumer confidence (10 percent).

Based on the analysis, Texas ranked as the third best state equipped to survive the economic fallout from COVID-19. Texas ranked No. 1 in the study's emergency reserves and relief category, since the Lone Star State has the second-highest CARES Act endowment at over $10 billion.

"The state also possesses adequate economic reserves and offers decent compensation for the unemployed. When these factors are combined with a relatively low cost of living and what is considered to be a pro-business environment, Texas just might be 'the case study for economic recovery from the COVID-19 recession,'" the report reads.

In contrast, New York is ranked at the bottom of the list at No. 50 due to its disproportionate amount of cases and high density in New York City. The top 10 states are as follows:

  1. Ohio
  2. South Dakota
  3. Texas
  4. Wyoming
  5. New Mexico
  6. Arkansas
  7. Iowa
  8. Utah
  9. West Virginia
  10. Nebraska

Midwestern states did particularly well in the report due to their low density and lack of tourism. Texas too shares these elements, as well as boasting a balance between city and rural environments. Even though Texas is the second-most populous state in the United States, it ranks as No. 24 for density. The Lone Star State's economy was factored in as well with it having the second largest economy by GDP in the U.S. Plus, the state's economy represents a variety of industries — like agriculture, aeronautics, and computer technology.

"So while the state has indeed taken its share of bumps from the current recession, it seems that it has enough resources to weather the storm," according to the report.

The study, which was published June 22, used data that came from sources such as the U.S. Department of Labor, Moody's Analytics, the U.S. Census, the Tax Foundation, the New York Times, and the Center on Budget and Policy Priorities.

The new programming geared at idea-stage startups has officially commenced at TMC Innovation Institute. Courtesy of TMCx

New TMCx program launches, C-level execs named at Houston startups, and more innovation news

Short stories

There's been a lot of recent Houston innovation news, and you might have missed something. Keep up to date with all the news happening among startups and technology in Houston in this innovation news roundup.

If you know of innovation-focused news happening, email me at natalie@innovationmap.com with the details andsubscribe to our daily newsletterthat sends fresh stories straight to your inboxes every morning.

TMCalpha premieres 

Courtesy of TMC

The Texas Medical Center has long counseled budding medical entrepreneurs in various capacities through its TMC Innovation Institute, but wanted to introduce programming specifically for early-stage companies. That's how TMC alpha was born and announced at the most recent TMCx Demo Day.

The program officially launched on July 18 and will host meetups on the third Thursday of every month.

"Over the past five years, TMC Innovation has blossomed into a global proving ground for healthcare startup companies from across the world, and we could not be more pleased with the myriad ways in which the ecosystem here has expanded in nature," says TMC Innovation Director Tom Luby in a release. "That being said, we realized that TMC Innovation needed to do more for the local innovation community and offer ample resources to support homegrown talent from within the confines of the largest medical city in the world. With TMC alpha, the hope is to connect anyone with a fledgling healthcare idea to the TMC Innovation network and create a two-way channel of meaningful dialogue."

Innowatts scores extra funding and names new C-level exec

Photo via innowatts.com

Houston-based AI-enabled analytics company, Innowatts, is growing in more ways than one. The company, which is fresh off an over $18.2 million Series B fundraise, added move funds and a new C-level executive.

Veronorte, a South American venture capital firm backed by one of the largest utilities in Colombia, became an additional investor in the company with an undisclosed contribution. Meanwhile, Eric Danziger joined the company as its new chief revenue officer. He will be tasked with the growth and sales of Innowatts' eUtility™ product.

"As the utility grid becomes more complex with the proliferation of electric vehicles and distributed generation," says Danziger in a release, "utility companies have to adapt to the data generated and needs of their consumers to manage these complex requirements."

Startup snags free office space prize

Photo courtesy of The Cannon

Shoot, a digital marketplace that simplifies the photographer and videographer booking process, has scored free office space in the newly opened Cannon building after receiving the second annual Insperity Innovation Scholarship.

The company was co-founded by Simbai Mutandiro and Alina Merida and has already launched its beta platform. The company will release its next version of the platform soon.

"Our relationship with The Cannon and the Insperity Innovation Scholarship are part of our initiative to help startups become successful more quickly by connecting and collaborating with like-minded individuals," says Larry Shaffer, Insperity senior vice president of marketing and business development, in a release. "We congratulate Shoot on receiving this scholarship and wish the co- founders continued success in furthering their entrepreneurial dream."

The other three finalists in the contest — Delfin, Social Chains, and SOTAOG — will receive open desk memberships at The Cannon for six months.

Houston falls low on the list of cities booming with growing private companies

Texas Money

Getty Images

When it comes to the major metros with the biggest jump in private businesses with over $1 million in revenue, Houston is the last on the list for Texas cities. LendingTree looked at the data, and, between 2014 and 2016, Houston only saw an increase of 4.9 percent in million-dollar business growth. This earned the Bayou City a No. 32 ranking across the country.

Dallas was slightly ahead of Houston with 5.2 percent growth and a No. 29 rank. Meanwhile, Austin earned the top spot with 15.1 percent growth. San Antonio, the only other Texas metro in the study, ranked No. 12 with 9 percent growth.

Nesh forms partnership

Oil rig

Photo courtesy of Thomas Miller/Breitling Energy

The Woodlands-based WellDatabase has announced a partnership with Nesh, an AI-optimized tool that's like the Siri or Alexa of oil and gas.

"The technology is amazing and we are thrilled to work with the Nesh team," writes John Ferrell, CEO of WellDatabase, in a blog post. "The integration allows Nesh to run real-time queries against WellDatabase. Users can ask a multitude of questions and get instant answers. They can also work with the Nesh team directly to train and build new questions and workflows."

Rice University and Cognite join forces

Courtesy of Cognite

When Oslo, Norway-based Cognite announced its dual U.S. headquarters in Houston and Austin, it had plans to engage universities from the get go. Now, the company, which specializes in data software with industrial applications, has officially created a partnership and internship program with Rice University.

"This partnership illustrates Cognite's commitment to attracting top people to build the most talented software engineering team in the world," says John Markus Lervik, Cognite co-founder and CEO, in a release. "Cognite solves some of the most complex problems related to industrial digitalization. To do that, we need the best minds, so partnering with Rice University was a natural choice."

Rice students are currently in Norway this summer working for Cognite as a part as the inaugural program.

The Cannon teams up with Thompson & Knight

Courtesy of The Cannon

Houston-based law firm Thompson & Knight has officially signed on to provide resources for The Cannon startups in a strategic partnership between the two companies.

"Thompson & Knight is pleased to partner with Houston-based entrepreneurs who are building the innovation, services, and technological platforms of the very near future," says Mark M. Sloan, managing partner of Thompson & Knight, in a news release. "We will offer our experience in the issues common to startup businesses, including intellectual property, technology, corporate, labor, and other areas of counsel that will help further the goals of these pioneering companies."

The law firm will have an office in The Cannon's recently opened building in West Houston.

Solugen names president

Getty Images


In May, Houston-based chemicals company, Solugen Inc., closed a $32 million round. Now, the company has put a portion of that money to work to hired the newest executive on the team. Jason Roberts, who has a decade of chemicals and oil and gas experience, has joined Solugen as president.

"What I found most compelling about Solugen was the company's quick successes and their overarching goal of decarbonizing the chemicals industry," says Roberts in a release. "The company's fundamental chemistry and technologies have created products that no one in the industry currently has. I am excited to join this young company's fast moving team at such a significant time in its history and look forward to helping scale their innovative products and services."

The Lone Star State stands out for being the best to start a business. Photo by gguy44/Getty Images

Texas named the No. 1 state to start a business

Startup friendly

The entrepreneurial spirit is best cultivated by Texans, apparently. The Lone Star State comes in first place for being business-friendly to startups and their founders in a recent study.

Out of all 50 states, Texas reigns supreme in WalletHub's report of the best and worst states to start a business. Texas earns a score of 61.05, which factored in business environment, access to resources, and business costs. Of those factors, the state ranked No. 1 for business environment, No. 11 for access to resources, and No. 30 for business costs.

Zeroing in on some key factors, Texas was recognized for having the fourth highest average growth in small businesses and the fifth highest total spending on incentives as its percent of gross domestic product. Texas also has the fourth longest work week by hours.

Texas edged out No. 2 Utah by a mere 0.1 points. The rest of the top five includes Georgia, North Dakota, and Oklahoma, respectively. At the bottom of the rankings are Connecticut, Hawaii, New Hampshire, New Jersey, and Rhode Island.

"In looking at the main criteria WalletHub used to determine their best startup state ranking — namely business environment, access to resources and business costs — it's clear why Texas would come in at No. 1," Susan Davenport, senior vice president of economic development for the Greater Houston Partnership, tells InnovationMap. "These are all areas where the Lone Star State consistently excels and why Texas continues to attract both entrepreneurs and existing companies across industry sectors."

Houston recently received a similar distinction from the personal finance site. In May, WalletHub used 19 key metrics — such as five-year business-survival rate and office-space affordability — to name Houston the No. 13 best city for starting a business out of 100 of the largest U.S. metros. In that study, a total of seven Texas cities made the top 20.

"Here in Houston, we're seeing growth in tech-related startups in particular and an increasing momentum of activity to support growth stage companies including the development of The Ion and the TMC3 commercialization campus, and the opening of The Cannon start-up hub, among several others," Davenport adds.

Texas also has a favorable business climate for female entrepreneurs in particular, one study found. Texas moved up to No. 1 from No. 8 in 2018 in this report by Fit Small Business that published in January.

Meanwhile, while known for being best for business, Texas is far from the top ranking in a study that analyzed the states' overall capacity. Texas came in at No. 38 in U.S. News & World Report's best states rankings for 2019, but even this report recognized Texas' business climate.

"Texas' diverse industrial base has drawn many businesses and workers in recent decades because of light regulation, low taxes and a low cost of labor," U.S. News says. "Entrepreneurs are particularly attracted to Austin, which emerged as a major player in the technology industry in the 1990s. Its 'South by Southwest' is one of the preeminent national tech conferences."

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This article was updated to include the comment from GHP.

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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

money moves

Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.