Texas named a top state for businesses to survive the pandemic

data point

The Lone Star State's mix of rural and urban settings — and other factors — has set it up for success as the economy reels from the COVID-19 pandemic. Photo by gguy44/Getty Images

A new study has found that businesses in Texas are in a good position to weather the storm that is the COVID-19 pandemic and subsequent economic challenges.

The FitSmallBusiness.com ranking factored in various metrics from overall financial health and emergency reserves to even how consumers feel about their state's ability to bounce back. The researchers weighted five metrics: Economic and financial Health (20 percent); least economic stressors (25 percent); emergency reserves and relief (25 percent); COVID-19 rates and health care infrastructure (20 percent); and consumer confidence (10 percent).

Based on the analysis, Texas ranked as the third best state equipped to survive the economic fallout from COVID-19. Texas ranked No. 1 in the study's emergency reserves and relief category, since the Lone Star State has the second-highest CARES Act endowment at over $10 billion.

"The state also possesses adequate economic reserves and offers decent compensation for the unemployed. When these factors are combined with a relatively low cost of living and what is considered to be a pro-business environment, Texas just might be 'the case study for economic recovery from the COVID-19 recession,'" the report reads.

In contrast, New York is ranked at the bottom of the list at No. 50 due to its disproportionate amount of cases and high density in New York City. The top 10 states are as follows:

  1. Ohio
  2. South Dakota
  3. Texas
  4. Wyoming
  5. New Mexico
  6. Arkansas
  7. Iowa
  8. Utah
  9. West Virginia
  10. Nebraska

Midwestern states did particularly well in the report due to their low density and lack of tourism. Texas too shares these elements, as well as boasting a balance between city and rural environments. Even though Texas is the second-most populous state in the United States, it ranks as No. 24 for density. The Lone Star State's economy was factored in as well with it having the second largest economy by GDP in the U.S. Plus, the state's economy represents a variety of industries — like agriculture, aeronautics, and computer technology.

"So while the state has indeed taken its share of bumps from the current recession, it seems that it has enough resources to weather the storm," according to the report.

The study, which was published June 22, used data that came from sources such as the U.S. Department of Labor, Moody's Analytics, the U.S. Census, the Tax Foundation, the New York Times, and the Center on Budget and Policy Priorities.

The new programming geared at idea-stage startups has officially commenced at TMC Innovation Institute. Courtesy of TMCx

New TMCx program launches, C-level execs named at Houston startups, and more innovation news

Short stories

There's been a lot of recent Houston innovation news, and you might have missed something. Keep up to date with all the news happening among startups and technology in Houston in this innovation news roundup.

If you know of innovation-focused news happening, email me at natalie@innovationmap.com with the details and subscribe to our daily newsletter that sends fresh stories straight to your inboxes every morning.

TMCalpha premieres 

Courtesy of TMC

The Texas Medical Center has long counseled budding medical entrepreneurs in various capacities through its TMC Innovation Institute, but wanted to introduce programming specifically for early-stage companies. That's how TMC alpha was born and announced at the most recent TMCx Demo Day.

The program officially launched on July 18 and will host meetups on the third Thursday of every month.

"Over the past five years, TMC Innovation has blossomed into a global proving ground for healthcare startup companies from across the world, and we could not be more pleased with the myriad ways in which the ecosystem here has expanded in nature," says TMC Innovation Director Tom Luby in a release. "That being said, we realized that TMC Innovation needed to do more for the local innovation community and offer ample resources to support homegrown talent from within the confines of the largest medical city in the world. With TMC alpha, the hope is to connect anyone with a fledgling healthcare idea to the TMC Innovation network and create a two-way channel of meaningful dialogue."

Innowatts scores extra funding and names new C-level exec

Photo via innowatts.com

Houston-based AI-enabled analytics company, Innowatts, is growing in more ways than one. The company, which is fresh off an over $18.2 million Series B fundraise, added move funds and a new C-level executive.

Veronorte, a South American venture capital firm backed by one of the largest utilities in Colombia, became an additional investor in the company with an undisclosed contribution. Meanwhile, Eric Danziger joined the company as its new chief revenue officer. He will be tasked with the growth and sales of Innowatts' eUtility™ product.

"As the utility grid becomes more complex with the proliferation of electric vehicles and distributed generation," says Danziger in a release, "utility companies have to adapt to the data generated and needs of their consumers to manage these complex requirements."

Startup snags free office space prize

Photo courtesy of The Cannon

Shoot, a digital marketplace that simplifies the photographer and videographer booking process, has scored free office space in the newly opened Cannon building after receiving the second annual Insperity Innovation Scholarship.

The company was co-founded by Simbai Mutandiro and Alina Merida and has already launched its beta platform. The company will release its next version of the platform soon.

"Our relationship with The Cannon and the Insperity Innovation Scholarship are part of our initiative to help startups become successful more quickly by connecting and collaborating with like-minded individuals," says Larry Shaffer, Insperity senior vice president of marketing and business development, in a release. "We congratulate Shoot on receiving this scholarship and wish the co- founders continued success in furthering their entrepreneurial dream."

The other three finalists in the contest — Delfin, Social Chains, and SOTAOG — will receive open desk memberships at The Cannon for six months.

Houston falls low on the list of cities booming with growing private companies

Texas Money

Getty Images

When it comes to the major metros with the biggest jump in private businesses with over $1 million in revenue, Houston is the last on the list for Texas cities. LendingTree looked at the data, and, between 2014 and 2016, Houston only saw an increase of 4.9 percent in million-dollar business growth. This earned the Bayou City a No. 32 ranking across the country.

Dallas was slightly ahead of Houston with 5.2 percent growth and a No. 29 rank. Meanwhile, Austin earned the top spot with 15.1 percent growth. San Antonio, the only other Texas metro in the study, ranked No. 12 with 9 percent growth.

Nesh forms partnership

Oil rig

Photo courtesy of Thomas Miller/Breitling Energy

The Woodlands-based WellDatabase has announced a partnership with Nesh, an AI-optimized tool that's like the Siri or Alexa of oil and gas.

"The technology is amazing and we are thrilled to work with the Nesh team," writes John Ferrell, CEO of WellDatabase, in a blog post. "The integration allows Nesh to run real-time queries against WellDatabase. Users can ask a multitude of questions and get instant answers. They can also work with the Nesh team directly to train and build new questions and workflows."

Rice University and Cognite join forces

Courtesy of Cognite

When Oslo, Norway-based Cognite announced its dual U.S. headquarters in Houston and Austin, it had plans to engage universities from the get go. Now, the company, which specializes in data software with industrial applications, has officially created a partnership and internship program with Rice University.

"This partnership illustrates Cognite's commitment to attracting top people to build the most talented software engineering team in the world," says John Markus Lervik, Cognite co-founder and CEO, in a release. "Cognite solves some of the most complex problems related to industrial digitalization. To do that, we need the best minds, so partnering with Rice University was a natural choice."

Rice students are currently in Norway this summer working for Cognite as a part as the inaugural program.

The Cannon teams up with Thompson & Knight

Courtesy of The Cannon

Houston-based law firm Thompson & Knight has officially signed on to provide resources for The Cannon startups in a strategic partnership between the two companies.

"Thompson & Knight is pleased to partner with Houston-based entrepreneurs who are building the innovation, services, and technological platforms of the very near future," says Mark M. Sloan, managing partner of Thompson & Knight, in a news release. "We will offer our experience in the issues common to startup businesses, including intellectual property, technology, corporate, labor, and other areas of counsel that will help further the goals of these pioneering companies."

The law firm will have an office in The Cannon's recently opened building in West Houston.

Solugen names president

Getty Images


In May, Houston-based chemicals company, Solugen Inc., closed a $32 million round. Now, the company has put a portion of that money to work to hired the newest executive on the team. Jason Roberts, who has a decade of chemicals and oil and gas experience, has joined Solugen as president.

"What I found most compelling about Solugen was the company's quick successes and their overarching goal of decarbonizing the chemicals industry," says Roberts in a release. "The company's fundamental chemistry and technologies have created products that no one in the industry currently has. I am excited to join this young company's fast moving team at such a significant time in its history and look forward to helping scale their innovative products and services."

The Lone Star State stands out for being the best to start a business. Photo by gguy44/Getty Images

Texas named the No. 1 state to start a business

Startup friendly

The entrepreneurial spirit is best cultivated by Texans, apparently. The Lone Star State comes in first place for being business-friendly to startups and their founders in a recent study.

Out of all 50 states, Texas reigns supreme in WalletHub's report of the best and worst states to start a business. Texas earns a score of 61.05, which factored in business environment, access to resources, and business costs. Of those factors, the state ranked No. 1 for business environment, No. 11 for access to resources, and No. 30 for business costs.

Zeroing in on some key factors, Texas was recognized for having the fourth highest average growth in small businesses and the fifth highest total spending on incentives as its percent of gross domestic product. Texas also has the fourth longest work week by hours.

Texas edged out No. 2 Utah by a mere 0.1 points. The rest of the top five includes Georgia, North Dakota, and Oklahoma, respectively. At the bottom of the rankings are Connecticut, Hawaii, New Hampshire, New Jersey, and Rhode Island.

"In looking at the main criteria WalletHub used to determine their best startup state ranking — namely business environment, access to resources and business costs — it's clear why Texas would come in at No. 1," Susan Davenport, senior vice president of economic development for the Greater Houston Partnership, tells InnovationMap. "These are all areas where the Lone Star State consistently excels and why Texas continues to attract both entrepreneurs and existing companies across industry sectors."

Houston recently received a similar distinction from the personal finance site. In May, WalletHub used 19 key metrics — such as five-year business-survival rate and office-space affordability — to name Houston the No. 13 best city for starting a business out of 100 of the largest U.S. metros. In that study, a total of seven Texas cities made the top 20.

"Here in Houston, we're seeing growth in tech-related startups in particular and an increasing momentum of activity to support growth stage companies including the development of The Ion and the TMC3 commercialization campus, and the opening of The Cannon start-up hub, among several others," Davenport adds.

Texas also has a favorable business climate for female entrepreneurs in particular, one study found. Texas moved up to No. 1 from No. 8 in 2018 in this report by Fit Small Business that published in January.

Meanwhile, while known for being best for business, Texas is far from the top ranking in a study that analyzed the states' overall capacity. Texas came in at No. 38 in U.S. News & World Report's best states rankings for 2019, but even this report recognized Texas' business climate.

"Texas' diverse industrial base has drawn many businesses and workers in recent decades because of light regulation, low taxes and a low cost of labor," U.S. News says. "Entrepreneurs are particularly attracted to Austin, which emerged as a major player in the technology industry in the 1990s. Its 'South by Southwest' is one of the preeminent national tech conferences."

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This article was updated to include the comment from GHP.

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Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

5+ must-know application deadlines for Houston innovators

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Editor's note: As 2026 ramps up, the Houston innovation scene is looking for the latest groups of innovative startups that'll make an impact. A number of accelerators and competitions have opened applications. Read below to see which might be a good fit for you or your venture. And take careful note of the deadlines. Please note: this article may be updated to include additional information and programs.

Did we miss an accelerator or competition accepting applications? Email innoeditor@innovationmap.com for editorial consideration.

2026 HCC Business Plan Competition

Deadline: Jan. 26

Details: HCC’s annual Business Plan Competition (BPC) is an opportunity for proposed, startup and existing entrepreneurs to develop focused plans to start or grow their businesses. Accepted teams will be announced and training will begin in late February and run through early June, with six free, three-hour training sessions. Advising will be provided to each accepted team. Applicants can apply as a team of up to five persons. Finalists will present to to gudges on May 27, 2026. Last year, $26,000 was awarded in seed money to the top five teams. In-kind prizes were also awarded to all graduating teams including free products, services and memberships, with an estimated in-kind value totaling $147,000. Find more information here.

University of Houston Technology Bridge Innov8 Hub (Spring 2026)

Deadline: Jan . 30

Details: UHTB Innov8 Hub’s immersive, 12-week startup acceleration program designed to help early-stage founders launch and scale their technology startups. Selected participants will gain access to expert mentors and advisors, collaborate with a cohort of peers, and compete for cash prizes during our final pitch event. The cohort begins Feb. 16, 2026. The program culminates in Pitch Day, where participants present their ventures to an audience of investors and partners from across the UH innovation ecosystem. Find more information here.

Rice Business Plan Competition 2026

Deadline: Jan. 31

Details: The Rice Business Plan Competition, hosted by the Rice Alliance for Technology and Entrepreneurship, gives collegiate entrepreneurs real-world experience to pitch their startups, enhance their business strategy and learn what it takes to launch a successful company. Forty-two teams will compete for more than $1 million in cash, investments and prizes on April 9-11, 2026. Find more information here.

Rice Veterans Business Battle 2026

Deadline: Jan. 31

Details: The Rice Veterans Business Battle is one of the nation’s largest pitch competitions for veteran-led startups, providing founders with mentorship, exposure to investors and the opportunity to compete for non-dilutive cash prizes. The event has led to more than $10 million of investments since it began in 2015. Teams will compete April 8-9, 2026. Find more information here.

TEX-E Fellows Application 2026-2027

Deadline: Feb. 10

Details: The TEX‑E Fellowship is a hands-on program designed for students interested in energy, climate, and entrepreneurship across Texas. It connects participants with industry mentors, startup founders, investors and academic leaders while providing practical, "real-world" experience in customer discovery, business modeling, and energy-transition innovation. Fellows gain access to workshops, real-world projects, and a statewide network shaping the future of energy and climate solutions. Participants must be a student at PVAMU, UH, UT Austin, Rice University, MIT or Texas A&M. Find more information here.

2026 Energy Venture Day & Pitch Competition

Deadline: Feb. 13

Details: The Rice Alliance, the Houston Energy Transition Initiative (HETI) and TEX-E will present the annual Energy Venture Day and Pitch Competition during CERAWeek on March 24-25, 2026. Energy Venture Day features two days of presentations by energy tech ventures driving efficiency and advancements toward the energy transition. On March 24, the Pitch Preview at the Ion will feature over 50 companies presenting in front of Rice Alliance's robust network of investors and industry partners. On March 25, the Energy Venture Day and Pitch Competition during CERAWeek will showcase 36 ventures at the George R Brown Convention Center. The pitch competition is divided up into the TEX-E university track, in which Texas student-led energy startups compete for $50,000 in cash prizes, and the industry ventures track. The industry track is subdivided into three additional tracks, spanning materials to clean energy. The top three companies from each industry track will be named. The winner of the CERAWeek competition will also have the chance to advance and compete for the $1 million investment prize at the Startup World Cup. Find more information here.

Greentown Go Make 2026

Deadline: March 10

Details: Greentown Go Make 2026 is an open-innovation program with Shell and Technip Energies. The six-month program is advancing industrial decarbonization by accelerating catalytic innovations. Selected startups will gain access to a structured platform to engage leadership from Shell and Technip Energies and explore potential partnership outcomes, including pilots and demonstrations. They’ll also receive networking opportunities, partnership-focused programming, and marketing visibility throughout the program. The cohort will be selected in May. Find more information here.

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