Texas named a top state for businesses to survive the pandemic

data point

The Lone Star State's mix of rural and urban settings — and other factors — has set it up for success as the economy reels from the COVID-19 pandemic. Photo by gguy44/Getty Images

A new study has found that businesses in Texas are in a good position to weather the storm that is the COVID-19 pandemic and subsequent economic challenges.

The FitSmallBusiness.com ranking factored in various metrics from overall financial health and emergency reserves to even how consumers feel about their state's ability to bounce back. The researchers weighted five metrics: Economic and financial Health (20 percent); least economic stressors (25 percent); emergency reserves and relief (25 percent); COVID-19 rates and health care infrastructure (20 percent); and consumer confidence (10 percent).

Based on the analysis, Texas ranked as the third best state equipped to survive the economic fallout from COVID-19. Texas ranked No. 1 in the study's emergency reserves and relief category, since the Lone Star State has the second-highest CARES Act endowment at over $10 billion.

"The state also possesses adequate economic reserves and offers decent compensation for the unemployed. When these factors are combined with a relatively low cost of living and what is considered to be a pro-business environment, Texas just might be 'the case study for economic recovery from the COVID-19 recession,'" the report reads.

In contrast, New York is ranked at the bottom of the list at No. 50 due to its disproportionate amount of cases and high density in New York City. The top 10 states are as follows:

  1. Ohio
  2. South Dakota
  3. Texas
  4. Wyoming
  5. New Mexico
  6. Arkansas
  7. Iowa
  8. Utah
  9. West Virginia
  10. Nebraska

Midwestern states did particularly well in the report due to their low density and lack of tourism. Texas too shares these elements, as well as boasting a balance between city and rural environments. Even though Texas is the second-most populous state in the United States, it ranks as No. 24 for density. The Lone Star State's economy was factored in as well with it having the second largest economy by GDP in the U.S. Plus, the state's economy represents a variety of industries — like agriculture, aeronautics, and computer technology.

"So while the state has indeed taken its share of bumps from the current recession, it seems that it has enough resources to weather the storm," according to the report.

The study, which was published June 22, used data that came from sources such as the U.S. Department of Labor, Moody's Analytics, the U.S. Census, the Tax Foundation, the New York Times, and the Center on Budget and Policy Priorities.

The new programming geared at idea-stage startups has officially commenced at TMC Innovation Institute. Courtesy of TMCx

New TMCx program launches, C-level execs named at Houston startups, and more innovation news

Short stories

There's been a lot of recent Houston innovation news, and you might have missed something. Keep up to date with all the news happening among startups and technology in Houston in this innovation news roundup.

If you know of innovation-focused news happening, email me at natalie@innovationmap.com with the details and subscribe to our daily newsletter that sends fresh stories straight to your inboxes every morning.

TMCalpha premieres 

Courtesy of TMC

The Texas Medical Center has long counseled budding medical entrepreneurs in various capacities through its TMC Innovation Institute, but wanted to introduce programming specifically for early-stage companies. That's how TMC alpha was born and announced at the most recent TMCx Demo Day.

The program officially launched on July 18 and will host meetups on the third Thursday of every month.

"Over the past five years, TMC Innovation has blossomed into a global proving ground for healthcare startup companies from across the world, and we could not be more pleased with the myriad ways in which the ecosystem here has expanded in nature," says TMC Innovation Director Tom Luby in a release. "That being said, we realized that TMC Innovation needed to do more for the local innovation community and offer ample resources to support homegrown talent from within the confines of the largest medical city in the world. With TMC alpha, the hope is to connect anyone with a fledgling healthcare idea to the TMC Innovation network and create a two-way channel of meaningful dialogue."

Innowatts scores extra funding and names new C-level exec

Photo via innowatts.com

Houston-based AI-enabled analytics company, Innowatts, is growing in more ways than one. The company, which is fresh off an over $18.2 million Series B fundraise, added move funds and a new C-level executive.

Veronorte, a South American venture capital firm backed by one of the largest utilities in Colombia, became an additional investor in the company with an undisclosed contribution. Meanwhile, Eric Danziger joined the company as its new chief revenue officer. He will be tasked with the growth and sales of Innowatts' eUtility™ product.

"As the utility grid becomes more complex with the proliferation of electric vehicles and distributed generation," says Danziger in a release, "utility companies have to adapt to the data generated and needs of their consumers to manage these complex requirements."

Startup snags free office space prize

Photo courtesy of The Cannon

Shoot, a digital marketplace that simplifies the photographer and videographer booking process, has scored free office space in the newly opened Cannon building after receiving the second annual Insperity Innovation Scholarship.

The company was co-founded by Simbai Mutandiro and Alina Merida and has already launched its beta platform. The company will release its next version of the platform soon.

"Our relationship with The Cannon and the Insperity Innovation Scholarship are part of our initiative to help startups become successful more quickly by connecting and collaborating with like-minded individuals," says Larry Shaffer, Insperity senior vice president of marketing and business development, in a release. "We congratulate Shoot on receiving this scholarship and wish the co- founders continued success in furthering their entrepreneurial dream."

The other three finalists in the contest — Delfin, Social Chains, and SOTAOG — will receive open desk memberships at The Cannon for six months.

Houston falls low on the list of cities booming with growing private companies

Texas Money

Getty Images

When it comes to the major metros with the biggest jump in private businesses with over $1 million in revenue, Houston is the last on the list for Texas cities. LendingTree looked at the data, and, between 2014 and 2016, Houston only saw an increase of 4.9 percent in million-dollar business growth. This earned the Bayou City a No. 32 ranking across the country.

Dallas was slightly ahead of Houston with 5.2 percent growth and a No. 29 rank. Meanwhile, Austin earned the top spot with 15.1 percent growth. San Antonio, the only other Texas metro in the study, ranked No. 12 with 9 percent growth.

Nesh forms partnership

Oil rig

Photo courtesy of Thomas Miller/Breitling Energy

The Woodlands-based WellDatabase has announced a partnership with Nesh, an AI-optimized tool that's like the Siri or Alexa of oil and gas.

"The technology is amazing and we are thrilled to work with the Nesh team," writes John Ferrell, CEO of WellDatabase, in a blog post. "The integration allows Nesh to run real-time queries against WellDatabase. Users can ask a multitude of questions and get instant answers. They can also work with the Nesh team directly to train and build new questions and workflows."

Rice University and Cognite join forces

Courtesy of Cognite

When Oslo, Norway-based Cognite announced its dual U.S. headquarters in Houston and Austin, it had plans to engage universities from the get go. Now, the company, which specializes in data software with industrial applications, has officially created a partnership and internship program with Rice University.

"This partnership illustrates Cognite's commitment to attracting top people to build the most talented software engineering team in the world," says John Markus Lervik, Cognite co-founder and CEO, in a release. "Cognite solves some of the most complex problems related to industrial digitalization. To do that, we need the best minds, so partnering with Rice University was a natural choice."

Rice students are currently in Norway this summer working for Cognite as a part as the inaugural program.

The Cannon teams up with Thompson & Knight

Courtesy of The Cannon

Houston-based law firm Thompson & Knight has officially signed on to provide resources for The Cannon startups in a strategic partnership between the two companies.

"Thompson & Knight is pleased to partner with Houston-based entrepreneurs who are building the innovation, services, and technological platforms of the very near future," says Mark M. Sloan, managing partner of Thompson & Knight, in a news release. "We will offer our experience in the issues common to startup businesses, including intellectual property, technology, corporate, labor, and other areas of counsel that will help further the goals of these pioneering companies."

The law firm will have an office in The Cannon's recently opened building in West Houston.

Solugen names president

Getty Images


In May, Houston-based chemicals company, Solugen Inc., closed a $32 million round. Now, the company has put a portion of that money to work to hired the newest executive on the team. Jason Roberts, who has a decade of chemicals and oil and gas experience, has joined Solugen as president.

"What I found most compelling about Solugen was the company's quick successes and their overarching goal of decarbonizing the chemicals industry," says Roberts in a release. "The company's fundamental chemistry and technologies have created products that no one in the industry currently has. I am excited to join this young company's fast moving team at such a significant time in its history and look forward to helping scale their innovative products and services."

The Lone Star State stands out for being the best to start a business. Photo by gguy44/Getty Images

Texas named the No. 1 state to start a business

Startup friendly

The entrepreneurial spirit is best cultivated by Texans, apparently. The Lone Star State comes in first place for being business-friendly to startups and their founders in a recent study.

Out of all 50 states, Texas reigns supreme in WalletHub's report of the best and worst states to start a business. Texas earns a score of 61.05, which factored in business environment, access to resources, and business costs. Of those factors, the state ranked No. 1 for business environment, No. 11 for access to resources, and No. 30 for business costs.

Zeroing in on some key factors, Texas was recognized for having the fourth highest average growth in small businesses and the fifth highest total spending on incentives as its percent of gross domestic product. Texas also has the fourth longest work week by hours.

Texas edged out No. 2 Utah by a mere 0.1 points. The rest of the top five includes Georgia, North Dakota, and Oklahoma, respectively. At the bottom of the rankings are Connecticut, Hawaii, New Hampshire, New Jersey, and Rhode Island.

"In looking at the main criteria WalletHub used to determine their best startup state ranking — namely business environment, access to resources and business costs — it's clear why Texas would come in at No. 1," Susan Davenport, senior vice president of economic development for the Greater Houston Partnership, tells InnovationMap. "These are all areas where the Lone Star State consistently excels and why Texas continues to attract both entrepreneurs and existing companies across industry sectors."

Houston recently received a similar distinction from the personal finance site. In May, WalletHub used 19 key metrics — such as five-year business-survival rate and office-space affordability — to name Houston the No. 13 best city for starting a business out of 100 of the largest U.S. metros. In that study, a total of seven Texas cities made the top 20.

"Here in Houston, we're seeing growth in tech-related startups in particular and an increasing momentum of activity to support growth stage companies including the development of The Ion and the TMC3 commercialization campus, and the opening of The Cannon start-up hub, among several others," Davenport adds.

Texas also has a favorable business climate for female entrepreneurs in particular, one study found. Texas moved up to No. 1 from No. 8 in 2018 in this report by Fit Small Business that published in January.

Meanwhile, while known for being best for business, Texas is far from the top ranking in a study that analyzed the states' overall capacity. Texas came in at No. 38 in U.S. News & World Report's best states rankings for 2019, but even this report recognized Texas' business climate.

"Texas' diverse industrial base has drawn many businesses and workers in recent decades because of light regulation, low taxes and a low cost of labor," U.S. News says. "Entrepreneurs are particularly attracted to Austin, which emerged as a major player in the technology industry in the 1990s. Its 'South by Southwest' is one of the preeminent national tech conferences."

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This article was updated to include the comment from GHP.

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Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

New accelerator joins the Ion and more Houston innovation news to know

Trending News

Editor's note: The Houston innovation scene is buzzing with big news this month, from a new accelerator joining the fold at the Ion to pre-IPO funding and national expansion plans. Below are the five most-read InnovationMap stories from Feb. 1-15, 2026:

New accelerator for AI startups to launch at Houston's Ion this spring

The new AI Native Dual-Use Sports, Health & Wellness Accelerator is expected to launch in March. Photo courtesy of the Ion

The Collectiv Foundation and Rice University have established a sports, health and wellness startup accelerator at the Ion District’s Collectiv, a sports-focused venture capital platform. The AI Native Dual-Use Sports, Health & Wellness Accelerator is scheduled to formally launch in March. Continue reading.

10+ can't-miss Houston business and innovation events in February

From recurring monthly favorites to the return of annual celebrations and summits, here's what not to miss in February. Photo courtesy the Ion.

February may be a short month, but its event calendar isn’t. From recurring monthly favorites to the return of annual celebrations and summits, here are the Houston business and innovation events not to miss — and how to register. Continue reading.

Houston lab-test startup seeks $1M for nationwide expansion

Jim Gebhart, founder and CEO of TheLabCafe.com. Courtesy photo.

Health care industry veteran Jim Gebhart knew there had to be a better way for patients to access lab services, especially those with high health insurance deductibles or no insurance at all. Continue reading.

Houston wearable biosensing company closes $13M pre-IPO round

Wellysis is known for its continuous ECG/EKG monitor with AI reporting, known as the S-Patch. Photo via wellysis.com.

Wellysis, a Seoul, South Korea-headquartered wearable biosensing company with its U.S. subsidiary based in Houston, has closed a $13.5 million pre-IPO funding round and plans to expand its Texas operations. Continue reading. Continue reading.

Texas booms as No. 3 best state to start a business right now

Texas is rebounding in a report of the best states to start a business. Photo via Getty Images

High employment growth and advantageous entrepreneurship rates have led Texas into a triumphant No. 3 spot in WalletHub's ranking of "Best and Worst States to Start a Business" for 2026. Continue reading.

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

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