Overheard: 5 powerful quotes from Houstonians speaking at SXSW

Eavesdropping in Austin

From advice to observations, these five quotes overheard at SXSW proves Houston had some great spokespeople at the 2019 SXSW Interactive festival. Photos courtesy

Houston had no shortage of representatives at the 2019 SXSW Interactive festival, which took place March 8 to 12 in Austin. Several sat on panels, lead mixers, or even starred in a movie for the film track of the conference.

I had the pleasure of sitting in on a great deal of these events featuring the best and the brightest of Houston's innovation stars, but I realize most did not. To catch you up and rid you of your fear of missing out, check out these five overheard quotes from the fest.

"I think it's so important to find your focus and know what to say no to, because you can't do it all. Elizabeth [Gore] and I have a monthly 'meeting of no' where we literally check off things off our plate that we need to stop doing because we just don't have enough time. It's probably one of our most valuable hours."

— Carolyn Rodz, co-founded Alice with Elizabeth Gore. Alice co-hosted a series of panels at the Bumble Hive. She was asked, during the investment-focused panel, about focusing on B-to-B vs. B-to-C as a startup. Alice and Bumble just recently announced a partnership.

"We're trying to awaken the sleeping giant — a really huge city with lots of money, trying to infiltrate and activate huge family offices and rally people behind the goal of building a vibrant startup community. We've got a long way to go in terms of attracting VC talent — we're still behind Austin and Dallas."

— Lawson Gow, founder and CEO of The Cannon, at the Austinpreneur podcast recording of "The Texas Startup Manifesto" episode. He was asked about what he's been trying to accomplish at The Cannon. Gow is the son of InnovationMap's parent company's CEO.

"We've got all the basic tools, and we know what the main issues are. There's still a lot to do, but we need to be smart and do fact-based and mechanism-based combinations."

— James Allison, chair of Immunology and executive director of the Immunotherapy Platform at MD Anderson Cancer Center. At his panel, "Making the Fight Against Cancer Even More Personal," he was asked about the current status of immunotherapy research.

“Have very specific questions. I hate the ‘can I pick your brain’ request. If you want advice on something, ask me that specifically. And, show up at everything. … It’s not about what network you have, but how many networks you can get into.”

— Grace Rodriguez, CEO and executive director of Impact Hub Houston. On the "Equitable Growth Ecosystems for Entrepreneurs" panel, she was asked about how an entrepreneur might try to grow their network and mentorship.

"Houston is an incredibly industrial town. We have more Fortune 500 companies here than anywhere other than New York — most of them in the world of the dirty and dangerous. We don't have a lot of scooter companies."

— Gabriella Rowe, CEO of Station Houston. She was asked while on her panel, "Startup Funding: From Apprenticeships to Professions," about bootstrapping as a startup. Read more about this discussion here.

Houston, we have a problem — and it's helping local startups have access to funding. Photo by Zview/Getty Images

SXSW panelists: Improving access to funding is key for Houston's continued ecosystem growth

Show me the money

A few weeks ago, Mayor of Houston Sylvester Turner and Station Houston CEO Gabriella Rowe proclaimed that Houston's up-and-coming innovation ecosystem was no longer up and coming: It had arrived. But what preceded that proclamation was years of figuring out what it was Houston could do to get to this point.

"We're the fourth largest city in the United States, and in 2015 were ranked 20th out of 25 ecosystems," Rowe says at a panel at the 2019 SXSW Interactive festival.

Following that shocking news, Rowe says the city's focus was on building tools — accelerators, incubators, education — but nowhere did anyone talk about funding. Now, years later, with plenty of accelerators, workspaces, and educational programs, Rowe says Houston now has a great pipeline of companies, but the problem is finding funding for them to tap into.

Entrepreneurs are looking for three things when it comes to finding ways to fund their companies, according to Rowe. They want it to be accessible capital — not something they have to take a class on to figure out how to get to it. They also want it to be impactful and local to where their headquarters is.

"When I think about accessible, impactful, and local, I think, well, not a lot falls into that category [in Houston]," Rowe says. "We're not doing it particularly well right now."

It's a structural problem, according to Rowe. While the city has built up its entrepreneurial climate, it hasn't yet made the same effort with investors.

"Even if we have one or two funds, we need an ecosystem that supports funding in the same way we have an ecosystem that supports entrepreneurs," she says.

Joe Milam, founder of Austin-based AngelSpan, an early stage investor relations platform, says the issue in Houston — and Austin — is that industries can be siloed. There's a huge need for an honest broker to connect the dots across the city, and that person needs to be impartial.

"You gotta care about your community first, before you care about your own agenda," Milam says. "Otherwise, you're going to flounder like Houston has, and how Austin still does."

One thing everyone agreed on during the Saturday, March 9, panel was that Houston has a lot of money, but it's been sitting on the sidelines. The mission is, in addition to bringing in venture capital firms, finding ways to engage money that's already in town.

"We have to produce tools to enable that capital that's hiding," Rowe says.

Houston-based PolyVascular earned recognition in two categories, as well as nabbing up to $25,000. Courtesy of TMC Innovation

2 TMCx companies leave SXSW with awards and grant money

Med tech

Two Houston companies are walking away from SXSW with awards and grant funds.

PolyVascular, a member of TMCx's 2017 medical device cohort, won the fifth annual Impact Pediatric Health pitch competition's medical device and health disparities and equity categories. Additionally, the Southwest National Pediatric Device Consortium granted the company up to $25,000.

PolyVascular co-founder Henri Justino represented his company in three-minute pitch, and team members Dan Harrington and Kwon Soo Chun were also in attendance.

The company was one of 12 finalists in the competition, which took place on March 8 at SXSW in Austin. Among the judges was Houston doctor, Chester Koh, professor of urology, pediatrics, and OB/GYN at Baylor College of Medicine and Pediatric Urologist at Texas Children's Hospital.

"At the Southwest National Pediatric Device Consortium, we are always looking for the next cutting-edge breakthrough in the world of medical devices," says Koh in a release. "Impact Pediatric Health's reputation for bringing together the leaders in pediatric medical technology innovations makes it the perfect venue to help identify and accelerate the next generation of medical device companies impacting our youngest of patients."

Founded in 2014, PolyVascular produces polymeric transcatheter valves for children with congenital heart disease — the most common birth defect and number one cause of infant mortality in the developed world. The company's goal is to reduce that number of infant deaths by introducing a higher quality of valves.

Meanwhile, VastBiome, a 2018 biodesign TMCx company, received a $1,000 grant and is now one of two finalists for the San Francisco-based Illumina Accelerator program. The company works with scientists with ongoing clinical trials focusing on the microbiome as it pertains to therapy.

Another TMCx company, Zibrio, was up for an award in the 2019 SXSW Pitch event, but left the contest empty handed.

TMCx has multiple representatives at the festival, and the organization partnered with Energizing Health to host events throughout the first weekend of the conference.

Jim Allison, immunotherapy researcher at MD Anderson and Nobel Prize recipient, is the subject of a new film that premiered at SXSW. Photo courtesy of MD Anderson Cancer Center

Film about Nobel Prize-winning Houston scientist premieres at SXSW

Now showing

For most of his career, James Allison has been a cancer research wildcatter fighting an oftentimes lonely battle for the advancement of immunotherapy. The medical community has historically been skeptical of the science, but nonetheless Allison dedicated his life to developing a better treatment to the disease that has claimed so many lives — including his mother's.

Last year, Allison, the chair of Immunology and executive director of the Immunotherapy Platform at MD Anderson, won the 2018 Nobel Prize in medicine, and Breakthrough, a film about Allison's progression from early researcher to Nobel Prize recipient, premiered on March 9 at the 2019 SXSW Interactive festival.

But despite the Nobel Prize and the new film both validating the science to the public, Allison says there's a lot more work to be done in immunotherapy. Allison, his colleague, Padmanee Sharma, and the filmmaker for Breakthrough, Bill Haney, hosted a discussion at SXSW about the future of immunotherapy.

"It's a time of considerable optimism — and we're just at the beginning," says Allison.

The film focuses on the man behind the science — a 70-year-old, harmonica-playing researcher from small-town Alice, Texas. It's both an ode to Allison's career and a thought-provoking take on all the work left to be done in the industry.

Immunotherapy is the process of targeting one's immune system's T-cells, infection-fighting white blood cells, to attack cancer cells. Sharma, a fellow MD Anderson oncology expert and clinician, says their work has received clinical approvals for treating Melanoma, kidney cancer, lung cancer, and bladder cancer. The scientists are now focused on expanding that treatment to other cancer types and building upon the established platform they've created, while also making sure nothing comes in the way of the facts of the science.

"It really requires that we dedicate ourselves to the basic science, understanding it and educating people about it, so we don't allow the facts and science get muddied by things that are political or nonfactual," Sharma says.

In a lot of ways, this is what Breakthrough has been able to do — communicate the facts on a platform where anyone can understand the science.

"We have a revolution on our hands, and thankfully we have people like Bill who can really tell the story well, because maybe as a scientist and a clinician, we're not always equally talented on telling the story to laypeople," Sharma says.

Moving forward, Allison says he's focused on finding out why the treatment fails in some instances, and he's determined to progress immunotherapy's success rate from the 20 to 40 percent rate he says he sees it at now to 100 percent.

"We've got all the basic tools, and we know what the main issues are," Allison says. "There's still a lot to do, but we need to be smart and do fact-based and mechanism-based combinations."

One of this week's top stories is about a Rice University professor discovering new ways to conserve Houston's prairie ecosystem, which might even result in flood mitigation. Courtesy of Cassidy Brown Johnson

5 most popular innovation stories in Houston this week

Now trending

Editor's note: It's been a truly exciting week for Houston innovation news — from a medical device company gaining FDA approval to a global accelerator program landing in Houston. Now, Houston innovators, investors, investors, and more are headed to SXSW to keep up the momentum.

5 Houston innovators headed to SXSW to know this week

Take a good look at these Houston entrepreneurs' faces, because you might be seeing them in downtown Austin next weekend for SXSW. Photos courtesy

Welcome to a special edition of InnovationMap's weekly innovators to know series. This week has more innovators featured than ever, and we're highlighting a particular group of people: The Houston founders headed for SXSW in Austin later this week. From startup founders, coworking space leaders, and pitch competition organizers, here's the Houston SXSW attendees you should know about. Continue reading.

Houston conservationist is helping to find new ways to protect local species and ecosystems

Memorial Park, which is currently undergoing a master plan renovation, and other Houston parks can be a great opportunity for introducing urban conservation inside the city limits. Rendering courtesy of Nelson Byrd Woltz

The Houston toad is a species that was discovered in Harris County in the 1950s. It has a very distinct, loud call that reverberates at quite a high pitch. But the Houston toad's call hasn't been heard in the city of Houston for almost 50 years. The species is locally extinct and critically endangered elsewhere. In fact, it's the most endangered amphibian in North America, says Cassidy Brown Johnson, a Rice University lecturer and president of the Coastal Prairie Partnership.

"When we think about extinction, we think of the dodo bird or the woolly mammoth," Johnson says. "But extinction is happening right underneath our noses." Continue reading.

Houston medical device company gains FDA approval

Houston-based Saranas has received de novo distinction from the FDA for its bleed monitoring technology. Courtesy of Saranas

When it comes to early bleeding detection, Houston-based Saranas, which closed $2.8 million in funding last year, is ahead of the game with its Early Bird Bleed Monitoring System. The Food and Drug Administration has recognized the medical device company and granted it De Novo distinction. Continue reading.

Exclusive: Global early stage accelerator program launches second Texas location in Houston

Palo Alto-based Founder Institute is launching its Houston program at Station Houston. Image courtesy Founder Institute

Silicon Valley-based Founder Institute has announced its second Texas program in Houston, which will operate out of Station Houston. Founder Institute Houston applications for the inaugural cohort close May 19. The early stage accelerator focuses on advancing startup companies in the pre-funding phase. Continue reading.

This new-to-Houston startup is simplifying trading for the next generation of investors

Andre Norman founded Jellifin, an options trading platform, flipping the script on the traditional investment process. Courtesy Jellfin

Say you're a young, working professional who wants to get involved in trading. Where do you start? If you get involved in options, which are contracts that give investors the ability to buy or sell a stock at a specific price on or before a specific date, you might go the traditional route and seek out a brokerage that focuses on options trading. There's a major catch, though: most brokerages tack on a fee of anywhere between $7 and $20 per trade, says Andre Norman, founder of Jellifin, an online options trading platform, is disrupting that norm. Continue reading.

From pitch competitions to panels, here's how Houstonians will be representing at SXSW. Marie Ketring/via sxsw.org

10 can't-miss events at SXSW featuring Houston speakers

South by the Bayou

Plenty of Houstonians, SXSW badge in hand, will be headed to Austin to network, learn, and share the stage with the rest of the festivals attendees. While InnovationMap has highlighted a few of the faces to be on the lookout for this weekend, here's a roundup of 10 events that have a Houston speaker or participant.

3/8 — Featured Session: Opening Speaker, Brené Brown

SXSW is starting right out of the gate with a Houstonian. Brene Brown, a research professor at the University of Houston, will be the keynote address. Her thoughtful talk will focus on community and one's sense of belonging.

The SXSW keynote address will be at 11 am on Friday, March 8, at the Austin Convention Center. Learn more.

3/8 — Hysteria No More: Data, Doctors and Women’s Health

Gone are the days that medical professionals dismiss women's health concerns as "hysteria," but there's still room for improvement on the matter. Three ob/gyns will talk about new ways women are finding health care solutions outside the doctor's office.

Rashmi Kudesia, physician at CCRM Fertility Houston, is one of the panelists, which occurs on Friday, March 8, at the JW Marriott. Learn more.

3/8 — Equitable Growth Ecosystems for Entrepreneurs panel

The country has an equity problem — especially when it comes to startups and funding. Nationally, venture capital funds are not distributed in a way that represents the populations diversity, so how does the industry right the course?

Grace Rodriguez of Impact Hub Houston is among the panel that will discuss this at 3:30 pm on Friday, March 8, at the Hilton Austin Downtown. Learn more.

3/9 — Austinpreneur: The Texas Startup Manifesto

Texas is among the growing innovation ecosystems in the world, but there's plenty of untapped potential. This Capital Factory panel will focus on taking Texas to the next level.

Lawson Gow, founder and CEO of The Cannon, will be a panelist at the event, which begins at 11 am on Saturday, March 9, at the Hilton Austin Downtown. Learn more.

3/9 — Startup Funding: From Apprenticeships to Professions

Venture capitalism has changed tenfold since its start. Looking back on the history of early stage funding can help predict where it's going — from Silicon Valley to every corner of the world.

Station Houston CEO Gabriella Rowe is on the panel, which will take place at 12:30 pm on Saturday, March 9, at the Hilton Austin Downtown. Learn more.

3/9 — Making the Fight Against Cancer Even More Personal

No one loves discussing cancer, but there's a large group of scientists who have to daily and they develop new technologies and innovations to help discover a cure for the deadly affliction.

James Allison, researcher at the University of Texas MD Anderson Cancer Center and 2018 Nobel Prize recipient, will be on the panel discussing ways to innovate within cancer research. The program starts at 5 pm on Saturday, March 9, at the JW Marriott. Learn more.

3/10 — SXSW Pitch Presented by Cyndx Awards Ceremony

Two Houston startups are competing for an award in the 11th annual SXSW Pitch Event. Fluidity Technologies will be presenting as its drone controller, FT Aviator, in the Hyper-Connected Communities category on Saturday, March 9, at 5 pm, and Zibrio SmartScale, which is in the Health and Wearable category, will present on Sunday, March 10, at 5 pm.

The pitch awards will take place at 6:30 pm on Sunday, March 10, at the Hilton Austin Downtown. Learn more.

3/11 — Tech Diversity Report Card 2019

Is diversity and inclusion basically just a myth in technology? Is it something that's attainable at this point, and what can the industry do to make that happen? A group of panelists discuss based on their experience and observations.

Heidi Hoover, head of office at Houston-based Flanders Investment & Trade, will be a member of the panel, which occurs on Monday, March 11, at 5 pm, at Capital Factory. Learn more.

3/11 — Angel Investor Meetup

Calling all acting and aspiring investors — it's time to rally. Two Texas investors are gathering the troops to discuss trends and opportunities in the state's — and the world's — investment sector.

Samantha Lewis of Houston-based GOOSE Society of Texas will be one of the hosts of the meetup, which takes place on Monday, March 11, at 5 p.m, at the Fairmont Hotel. Learn more.

3/12 — AI & IoT Panel and Emerging Company Showcase

Houston-based Baker Botts and Global Corporate Venturing are setting the stage for emerging tech companies to shine. The event includes a panel, a showcase, and an evening of networking.

James McKell, of Chevron Technology Ventures, is representing Houston on the panel, which begins at 2 pm on Tuesday, March 12, at Hotel Van Zandt. Learn more.

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Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

Texas space co. takes giant step toward lunar excavator deployment

Out of this world

Lunar exploration and development are currently hampered by the fact that the moon is largely devoid of necessary infrastructure, like spaceports. Such amenities need to be constructed remotely by autonomous vehicles, and making effective devices that can survive the harsh lunar surface long enough to complete construction projects is daunting.

Enter San Antonio-based Astroport Space Technologies. Founded in San Antonio in 2020, the company has become a major part of building plans beyond Earth, via its prototype excavator, and in early February, it completed an important field test of its new lunar excavator.

The new excavator is designed to function with California-based Astrolab's Flexible Logistics and Exploration (FLEX) rover, a highly modular vehicle that will perform a variety of functions on the surface of the moon.

In a recent demo, the Astroport prototype excavator successfully integrated with FLEX and proceeded to dig in a simulated lunar surface. The excavator collected an average of 207 lbs (94kg) of regolith (lunar surface dust) in just 3.5 minutes. It will need that speed to move the estimated 3,723 tons (3,378 tonnes) of regolith needed for a lunar spaceport.

After the successful test, both Astroport and Astrolab expressed confidence that the excavator was ready for deployment. "Leading with this successful excavator demo proves that our technology is no longer theoretical—it is operational," said Sam Ximenes, CEO of Astroport.

"This is the first of many implements in development that will turn Astrolab's FLEX rover into the 'Swiss Army Knife' of lunar construction. To meet the infrastructure needs of the emerging lunar economy, we must build the 'Port' before the 'Ship' arrives. By leveraging the FLEX platform, we are providing the Space Force, NASA, and commercial partners with a 'Shovel-Ready' construction capability to secure the lunar high ground."

"We are excited to provide the mobility backbone for Astroport's groundbreaking construction technology," said Jaret Matthews, CEO of Astrolab, in a release. "Astrolab is dedicated to establishing a viable lunar ecosystem. By combining our FLEX rover's versatility with Astroport's civil engineering expertise, we are delivering the essential capabilities required for a sustainable lunar economy."

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This article originally appeared on CultureMap.com.

Houston biotech co. raises $11M to advance ALS drug development

drug money

Houston-based clinical-stage biotechnology company Coya Therapeutics (NASDAQ: COYA) has raised $11.1 million in a private investment round.

India-based pharmaceuticals company Dr. Reddy’s Laboratories Inc. led the round with a $10 million investment, according to a news release. New York-based investment firm Greenlight Capital, Coya’s largest institutional shareholder, contributed $1.1 million.

The funding was raised through a definitive securities purchase agreement for the purchase and sale of more than 2.5 million shares of Coya's common stock in a private placement at $4.40 per share.

Coya reports that it plans to use the proceeds to scale up manufacturing of low-dose interleukin-2 (IL-2), which is a component of its COYA 302 and will support the commercial readiness of the drug. COYA 302 enhances anti-inflammatory T cell function and suppresses harmful immune activity for treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease.

The company received FDA acceptance for its investigational new drug application for COYA 302 for treating ALS and FTD this summer. Its ALSTARS Phase 2 clinical trial for ALS treatment launched this fall in the U.S. and Canada and has begun enrolling and dosing patients. Coya CEO Arun Swaminathan said in a letter to investors that the company also plans to advance its clinical programs for the drug for FTD therapy in 2026.

Coya was founded in 2021. The company merged with Nicoya Health Inc. in 2020 and raised $10 million in its series A the same year. It closed its IPO in January 2023 for more than $15 million. Its therapeutics uses innovative work from Houston Methodist's Dr. Stanley H. Appel.

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