From what you wear to where you go, here are some Houston fitness startups changing the game. Courtesy of Accel Lifestyle

Houston has developed into a city full of boutique fitness studios and updated parks, and now the city is seeing fitness startups popping up as well. From creating a smell-free fabric to engaging NASA technology into training, these Houston fitness startups are working out innovative ideas into the exercise industry.

Accel Lifestyle

Courtesy of Accel Lifestyle

Megan Eddings tried everything to get the stink out of her husband's workout clothes, but nothing worked completely. With her background in chemistry, she knew there was something she could do to create a fabric that didn't hold on to the bacteria that built up in normal fabrics. So, she got to work. Now, years later, she's finally perfected her product and is ready to launch by summer.

"I never thought it would take this so long to make a T-shirt," Eddings says. "But, if you do it right and in an ethical way, it just takes a little longer."

Eddings says she'll have six different styles of men's and women's shirts to start, and they will be available on the Accel website, which recently got a facelift. Read more about Accel's journey here.

Kanthaka

Courtesy of Kanthaka

Finding a quality personal training session that fits your schedule and location hasn't really been done before Houston-based Kanthaka launched in 2017. Founder Sylvia Kampshoff wanted something that allowed her to exercise with someone on her own schedule, and with people who valued customer service.

The app uses location technology similar to that of ride sharing apps to allow users to book training sessions with certified personal trainers, all of whom are heavily vetted and background checked by Kampshoff and her team.

"Many trainers at gyms or who work privately aren't certified," she says. "And that was important to me, that we have professionals who understand training and the body. And making sure our clients felt safe was a huge priority for me. We interview every trainer personally to ensure they not only meet our standards but also share our goals."

Since launch, Kanthaka has expanded to Austin and is expanding to San Antonio in April and Atlanta in May. The company has secured angel investment and has seen a month over month growth of 10 to 50 percent since the end of 2018. Read more about Kanthaka here.

Muvve

Courtesy of Muvve

What would you get if you crossed a dating app with an event planner focused on creating friendships around fitness? Houston-based Muvve. The app, which was created by Avi Ravishankar and Julian Se, came from the idea that working out, training for a marathon, or just staying active is way better with a buddy.

"Intrinsic motivation is hard to find, especially in individual sports, like running, cycling, or yoga," Ravishankar says. "Whereas, in team sports, like basketball or volleyball, you have the team to train with and motivate you."

The app, which launched in May of 2018, acts like a network for fitness lovers — just like a dating app would connect potential romantic partners. Dating apps, actually, were a big influence on Ravishankar, he says.

"I fell in love with dating apps. It was this mind-blowing idea for me of how many people you can connect with — even if it's not for dating," he says. "The amount of people I have met just through technology always blows my mind. There's so much power in it."

Ravishankar plans on growing the app's user base to 10,000 users by summer. Read more about Muvve here.

Sutaria Training & Fitness

Blake Hobson/ST&F

Sutaria Training & Fitness LLC, a Houston-based personal training company, has a new partnership with NASA that aims to provide exclusive access to astronaut training equipment to clients.

Jay Sutaria, founder and lead trainer, says that the equipment at NASA, called the force plate, shows how much power a client's body is producing in specific areas and how that power drops over time. The data produced by these machines can help trainers customize and tweak workouts for each client to take training a step further.

Sutaria and his partners at NASA recently tested the equipment with the Chinese olympic boxing team to see how it can be applied to workouts at NASA's location in Clear Lake.

"It's exclusive access to the equipment that is not available openly in Houston," says Sutaria. "NASA is a reference for us to become better trainers." Click here to read more about ST&F.

From cryotherapy and NASA-inspired fitness to startup funding and biotech, this week's innovators to know are raising the bar on health tech and innovation. Courtesy photos

4 health-focused Houston innovators to know this week

Who's who

This week's innovators to know are focused on health and wellness, from a Houston-based cryotherapy franchise to the person behind funding medical device and digital health startups. We couldn't narrow these folks down to the usual three, so here are the four Houston innovators to know as we start the last week in February.

Juliana Garaizar, director of the Texas Medical Center Venture Fund

Courtesy of TMC

Juliana Garaizar has worked all around the world, and her international contacts and venture capital experience has landed her at the heart of the Texas Medical Center leading the TMC Venture Fund.

"I think TMC wants to be positioned as a strong competitor to the East and West Coasts as a point of entry for companies coming to the United States, but also for technology and commercializations from hospitals," she tells InnovationMap. "The fact that I'm already very connected to other countries — not only from the funding side but also from the research side, is really helpful."

Garaizar has her hands full running the $25 million nonprofit fund that invests around $2 million a year. Recipients, which all have a connection to TMC either through the accelerator or workspaces, receive a range between $250,000 to $500,000, and can go up to $1 million in a deal, Garaizar says. She is focused on securing deal flow for the fund before growing it more.

"In the long term, we would like to raise a bigger fun, around $100 million fund," she says. "We would need to make sure we have our deal flow ready for that, and a big part of that would be international deal flow."

Read more about Garaizar and the TMC Venture Fund here.

Walter Klemp, chairman and CEO of Moleculin

Courtesy of Moleculin

It's pretty concerning to Walter Klemp that, while Houston has the world's largest medical center, "the tragic irony" is that other cities have far more biotech money ready to be invested.

"The Third Coast is really starved for capital," he tells InnovationMap. "What drew me into this was I was one of the few entrepreneurs that lived here that knew the ropes in terms of tapping into East and West Coast capital structures and could make that connection for them."

In 2007, chairman and CEO Walter Klemp founded Moleculin Biotech Inc. as a private company. The company has three core technologies currently being tested with some success, but the most promising is called WP1066, which uses propolis, a compound of beeswax, sap and saliva that bees produce to seal small areas of their hives, as a base. The active compound both downregulates the STAT3, a long-time Holy Grail in the cancer research world, and directly attacking the tumor, but also quieting T Cells, which allows the body's own immune system to fight the cancer itself. Essentially, it works both as chemotherapy and immunotherapy.

Read more about Klemp and Moleculin here.

Jay Sutaria, founder and lead trainer of Sutaria Training & Fitness

Courtesy of ST&F

Earthbound Houstonians have a chance to use NASA training equipment thanks to Jay Sutaria's company, Sutaria Training & Fitness.

"It's exclusive access to the equipment that is not available openly in Houston," Sutaria tells InnovationMap. "NASA is a reference for us to become better trainers."

Sutaria founded his company in 2011 while he was a student at the University of Houston, and the company now operates with two trainers. His clients include professional athletes such as D.J. Augustin (Orlando Magic, NBA); and Tim Frazier (New Orleans Pelicans, NBA), however, Sutaria and his team offer professional personal training services to any type of athlete.

Read more about Sutaria and ST&F here.

Kyle Jones, COO of iCRYO

Courtesy of iCryo

Kyle Jones says he's always known he was destined for entrepreneurship, and when he came across the potential of cryotherapy while working at a physical therapist office, he knew it was a scalable business.

He opened his first location of iCRYO in League City in 2015. Now the company is

Jones says he used the location to work out the kinks of his business model, since he didn't really have much to model after. One thing that was most important to Jones, with his PT background, was safety of the patients. He cared about this more than making money, he says.

"I knew first and foremost the one thing that the cryotherapy space didn't have was a certification program, which is kind of terrifying to me," Jones tells InnovationMap. "Any therapy has some type of schooling or certification — massage therapy and acupuncture both have it. Cryotherapy even to date does not a certification to it."

Read more about Jones and iCRYO here.


Jay Sutaria's personal training business is partnering with NASA to provide clients training fit for an astronaut. Blake Hobson/ST&F

Houston-based personal training company partners with NASA for out-of-this-world opportunity

Next level

Not everyone one can be an astronaut, but you might get to use their equipment. Sutaria Training & Fitness LLC, a Houston-based personal training company, is teaming up with one of the leading biomechanics that contracts with NASA that aims to provide exclusive access to astronaut training equipment to clients.

Jay Sutaria, founder and lead trainer, says that the equipment at NASA, called the force plate, shows how much power a client's body is producing in specific areas and how that power drops over time. The data produced by these machines can help trainers customize and tweak workouts for each client to take training a step further.

The Advanced Resistive Exercise Device, or ARED, works with the force plates Sutaria uses, and according to NASA's website, ARED includes force sensors located in the platform that are able to record force in three dimensions.

Sutaria and his contact at NASA recently tested the equipment with the Chinese olympic boxing team to see how it can be applied to workouts at NASA's location in Clear Lake.

"It's exclusive access to the equipment that is not available openly in Houston," said Sutaria. "NASA is a reference for us to become better trainers."

Sutaria founded his company in 2011 while he was a student at the University of Houston, and the company now operates with two trainers. His clients include professional athletes such as D.J. Augustin (Orlando Magic, NBA); and Tim Frazier (New Orleans Pelicans, NBA), however, Sutaria and his team offer professional personal training services to any type of athlete.

He says that his passion towards healing sports injuries stems from a back injury he suffered from throughout high school that greatly affected his performance. Sutaria had gone to physical therapy to repair the injury, but was trained incorrectly, which lead to more pain. After studying kinesiology and exercise science, he was able to fix his own chronic pain and help others like him.

"When I went into college with this physical therapy mindset, I wanted to help people get out of pain," Sutaria said.

In addition to his degree, Sutaria and all of the trainers on his team have diplomas from the National Personal Training Institute. Sutaria says that the trainers approach is data and science driven, focusing on a series of fundamental exercise movement and coaching.

"We've already helped hundreds of people, if you can help one person it's good for your community," said Sutaria.

ST&F is working to strengthen corporate partnerships, where the personal training company would offer mobility stretching training and nutritional guidance. He wants to open a gym this year; the company currently offers services out of Next Level Fitness in West University. The new gym will likely contain special equipment used at NASA, taking the collaboration even further. For now, clients that are interested in testing the equipment will have to travel to Clear Lake.

In addition to the permanent location, services are available in the Bellaire, River Oaks, Galleria, Heights, Sugar Land, Spring, Midtown, and Downtown neighborhoods, according to the website, and while Sutaria isn't writing off plans to expand to other cities, the company will remain focused on Houston for now.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."