Houston 3D printing company lands funding from NASA

funds granted

NASA doled out funding to 12 startups — and one from Houston makes the cut. Photo courtesy of re:3D

Houston-based re:3D Inc was recently one of 12 innovative companies from around the country to be granted Phase II awards from a NASA small business initiative, the space giant announced earlier this week.

The grants of up to $850,000 are awarded to early-stage, high-risk technology concepts that could be commercialized for use in space and on Earth as part of NASA's SBIR Ignite pilot, which is part of NASA’s Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs.

The program was launched to support emerging companies "whose end customers may not be only NASA but are still creating technology that NASA cares about,” Jason L. Kessler, program executive for the NASA SBIR/STTR program, says in a previous statement. And it aims to attract companies that have not yet worked with NASA.

The concepts from the cohort have applications in climate resilience, low-cost solar cells and active debris remediation. Re:3D Inc.'s project looks to develop a recycling system that uses a 3D printer to turn thermoplastic waste generated in orbit into functional and useful objects, according to the project's proposal.

SBIR Ignite made its inaugural Phase I awards in 2022, granting about $2 million in total to the 12 companies, including re:3D Inc. The Phase II grants are intended to help the companies create their prototypes.

“We are proud that all 12 of the small businesses are continuing with our program and persevering through the tough realities of early-stage research and development,” Kessler said in a statement made this month. "These awards foster a unique range of technologies that we hope will have positive impacts on the lives of everyday Americans in the future."

Re3D Inc. is the only company from Texas in the cohort. The other 11 awarded companies and their projects include:

  • Ampaire Inc.: High Efficiency Powertrain for Hybrid Aircraft
  • Canopy Aerospace Inc.: Reusable Heatshields through Additive Manufacturing
  • Cecilia Energy: Catalytic Conversion of Waste Plastic to Hydrogen
  • Crystal Sonic Inc.: Reducing Cost of Space Photovoltaics via Sound-Assisted Substrate Reuse
  • H3X Technologies Inc.: HPDM-30 – A 10 kW/kg Integrated Motor Drive for UAV and Aircraft Electric Propulsion
  • Outpost Technologies Corporation: Outpost Cargo Ferry: A Rapid Cargo Downmass Vehicle
  • Solestial, Inc.: Next Generation Silicon Based Solar Arrays for Space Stations and Other Permanent Space Infrastructure
  • StormImpact Inc.: Optimizing vegetation management to improve the resilience of the electrical power system to extreme weather
  • Terrafuse, Inc.: Wildfire Mitigation through Explainable Risk Predictions
  • Trans Astronautica Corporation: Mini Bee Capture Bag for Active Debris Remediation
  • Turion Space Corp.: Low-Cost CubeSat for Active Removal of Sizable Space Debris Utilizing a Mothership Architecture

Re:3D Inc. was founded in 2013 by NASA contractors Samantha Snabes and Matthew Fiedler and is based in Clear Lake. It's known for its GigaBot 3D printer, which uses recycled materials to create larger devices.

Since its founding it's been named to numerous accelerators and has earned national recognition, like the Tibbetts Award from the U.S. Small Business Administration, which honors small businesses that are at the forefront of technology. It was selected by the SBA to participate in its inaugural America’s Seed Fund Startup Expo last year.

Co-founder Snabes spoke on the Houston Innovators Podcast in 2020. Click here to listen to the full, in-depth interview.

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CellChorus, a biotech startup operating out of the University of Houston Technology Bridge, has secured fresh funding. Photo via Getty Images

Houston biotech startup secures $2.3M grant

cha-ching

They say it’s all in the timing. For CellChorus, it’s all in the TIMING. That’s Time-lapse Imaging Microscopy In Nanowell Grids. TIMING is a visual AI program that evaluates cell activation, killing and movement, which allows scientists to better understand how cells function.

The technology is important to the development of novel therapies in the realms of oncology, infectious diseases, and countless other disorders and diseases. By allowing scientists to observe those maladies at their roots, it will enable them to create, and ultimately deliver new medications and other therapies faster, at lower cost, and with a higher success rate.

CellChorus is a spinoff of the Single Cell Lab at the University of Houston. Part of UH’s Technology Bridge, CEO Daniel Meyer connected with co-founder and leader of Single Cell Lab, Navin Varadarajan, through co-founder Laurence Cooper.

“The company had been established, but there were limited operations,” recalls Meyer during a phone call with InnovationMap.

That was the fall of 2020. Now, the team has just announced a $2.3 million SBIR (Small Business Innovation Research) Fast-Track grant from the National Institute of General Medical Sciences.

“This funding will support development of a product offering that builds on the success of our early access laboratory,” Cooper said in a press release. “As the next frontier of cellular analysis, dynamic single-cell analysis will increase the impact that immunotherapies have in improving the lives of patients.”

Meyer is based in the Bay Area, but the rest of the team is in Houston. Meyer has a proven track record as an investor and early stage entrepreneur in life sciences companies, including work as COO of Genospace, which was acquired by HCA Healthcare.

Meyer says that what attracted him to CellChorus was a combination of a clear need for the technology and the fact that it was “very well validated.“

“Developers of immunotherapies need better functional data earlier so that they can develop and deliver better therapies,” he explains.

Another aspect of its appeal was the fact that more than 10 publications featured data from the TIMING platform.

“We’ve had both large and small biopharmas publish data,” says Meyer. “That’s important as well because it shows there’s applicability in both nonprofit and for-profit research.”

Though Meyer himself doesn’t currently live in Houston, he recognizes its importance to CellChorus. He says that it can be difficult for an early stage company to find appropriate lab space, so Technology Bridge was of exceptional importance for CellChorus. Since opening the lab a year and a half ago, Varadarajan and his team have been busy.

“Example projects we have completed include understanding mechanism of action for cell therapy products, selecting lead candidates for T cell engagers, identifying biomarkers of response to cell therapies, and quantifying potency and viability for cell therapy manufacturing technologies,” says Meyer.

And now, CellChorus is collaborating with leaders in the industry.

“These include top-25 biopharmaceutical companies and promising venture-backed biotechnology companies, as well as leading not-for-profit research institutions,” says Meyer in a press release. It’s clear that the TIMING is right for CellChorus to excel.

Here's your latest roundup of Houston startup and innovation news you may have missed. Photo via Getty Images

Mobile ordering rolls out at resort, Houston VC's latest investment, and more local innovation news

short stories

We're on the other side of the hill that is Houston's summer, but the Bayou City's still hot — especially in terms of innovation news, and there might be some headlines you may have missed.

In this roundup of short stories within Houston startups and tech, a Houston venture capital fund has made its latest investment, Houston startups share big updates, and more.

Rivalry Technology rolls out mobile ordering at hot summer spot

You can now order poolside at this Houston-area resort. Image courtesy of Rivalry Tech

Lounging at Margaritaville Lake Resort at Lake Conroe was just made easier by Rivalry Tech, a Houston-based mobile ordering platform company. Rivalry Tech upgraded poolside ordering with its myEATz. According to a news release, customers can now order food and drinks from the 5 o’Clock Somewhere Bar and Lone Palm Bar via a custom QR code system for each lounge chair and table to increase operational efficiency for the Margaritaville Lake Resort staff.

“We wanted to be sure the rollout of the myEATz mobile ordering platform was helpful to the Margaritaville staff, not a hindrance to their existing process. We created custom QR codes and a color coded map to easily identify where the mobile orders are going,” says Charles Willis, COO of Rivalry Tech, in the release.

Rivalry, which provides mobile ordering at numerous sports stadiums and venues with sEATz, expanded into hospitality this year.

“The Rivalry Tech team helped us to seamlessly implement mobile ordering at Margaritaville Lake Resort. They created the marketing materials, established custom QR codes, uploaded mentors and trained our staff onsite. The whole process has been easy and collaborative,” says Amit Sen, director food and beverage for Margaritaville Lake Resort, in the release.

Mercury Fund invests in ReturnLogic's latest round

Mercury has led the latest fundraising round from a SaaS company. Image via Getty Images

Houston-based venture capital firm Mercury led Phillidelphia-based SaaS company ReturnLogic's $8.5 million series A funding round, which also had participation from Revolution’s Rise of the Rest Fund, White Rose Ventures, and Ben Franklin Technology Partners. The fresh funding will help the company double its workforce, accelerate product development, and expand Application Programming Interface capabilities, according to a news release.

Founded by CEO Peter Sobotta, Return Logic's SaaS platform, which can be plugged into existing e-commerce platforms, helps to enhance management of returns and prevent the challenging financial impacts of returns.

“While retailers have largely mastered forward logistics to get products into customers hands, the returns process remains an under-addressed, resource-draining problem that eats away at brands’ profits,” says Blair Garrou, managing director of Mercury, in a news release. “ReturnLogic is something entirely new to this market and uniquely built on Peter Sobotta’s deep operational experience in reverse logistics and supply chain management.

"While serving in the U.S. Navy, Peter specialized in reverse logistics and gained extensive expertise in ecommerce operations," Garrou continues. "With Peter at the helm, ReturnLogic’s innovative API-first returns solution is well-positioned to tackle the ever-growing operational returns problem facing retailers. We are excited to partner with Peter and his team as they continue to solve this massive problem for online retailers.”

Fluence Analytics named a top advanced manufacturing startup

Fluence Analytics was selected as one of 50 startups recognized. Graphic courtesy

Fluence Analytics, an analytics and process control solutions platform for the polymer and biopharmaceutical industries, was named as a Top 50 global advanced manufacturing startup by CB Insights. The Inaugural list breaks down 16 different cohorts, narrowed down from more than 6,000 companies who either submitted an application or were nominated. Fluence Analytics was one of three companies featured in the R&D Optimization category.

"Our team is very excited that our real-time process analytics, optimization and control products for the polymer and biopharma industries are included among such elite startups," says Jay Manouchehri, CEO of Fluence Analytics, in a statement to InnovationMap. "We wish to thank CB Insights for including Fluence Analytics in its inaugural list of the Top 50 global advanced manufacturing startups, as well as our customers and investors for supporting the development and roll-out of our transformative technology solutions."

Fluence Analytics moved to the Houston area from New Orleans last year. The company's tech platform allows for optimization and control products to polymer and biopharmaceutical customers worldwide.

HTX Labs secures $1.7M contract to expand within United States Air Force

HTX Labs' EMPACT product will be further developed to support the Air Force. Image courtesy of HTX Labs

HTX Labs, a Houston-based company that designs extended reality training for military and business purposes, that it has been awarded a $1.7 million Small Business Innovation Research Phase II Tactical Funding Increase with the US Air Force to enhance and operationalize to its product, EMPACT Immersive Learning Platform, in support of training modernization.

“We are very thankful to AFWERX and AFDT for this great opportunity to play an increasingly important role in helping the USAF accelerate training modernization," says Chris Verret, president HTX Labs, in a news release. "This TACFI award shows continued confidence in HTX Labs, with a strong commitment to accelerate usage and adoption of EMPACT.”

HTX Labs will leverage this contract to expand EMPACT's ability to rapidly create and distribute interactive, immersive training, collaborating closely with Advanced Force Development Technologies, per the release.

OpenStax to publish free edition of updated science textbook

OpenStax is growing its access to free online textbooks. Image via openstax.org

OpenStax, a tech initiative from Rice University that uploads free learning resources, has announced it will publish the 10th edition of an organic chemistry textbook by Cornell University professor emeritus John McMurry.

“This is a watershed moment for OpenStax and the open educational resources (OER) movement,” says Richard Baraniuk, founder and director of OpenStax, in a news release. “This publication will quickly provide a free, openly licensed, high-quality resource to hundreds of thousands of students in the U.S. taking organic chemistry, removing what can be a considerable cost and access barrier.”

Usually a big expense for organic chemistry students, McMurry, with the support of publisher Cengage, made the decision to offer the latest edition online as a tribute to his son, Peter McMurry, who died in 2019 after a long struggle with cystic fibrosis.

“If Peter were still alive, I have no doubt that he would want me to work on this 10th edition with a publisher that made the book free to students,” McMurry says in the release. “To make this possible, I am not receiving any payment for this book, and generous supporters have covered not only the production costs but have also made a donation of $500,000 to the Cystic Fibrosis Foundation to help find a cure for this terrible disease.”

This innovative Houston company has the national spotlight this week. Courtesy of re:3D

Houston 3D printing company selected inaugural competition

winner, winner

A Houston company has been announced among the winners of an inaugural seed fund expo competition.

Twelve startups were announced across four categories in the U.S. Small Business Administration's inaugural America’s Seed Fund Startup Expo 2022, which is taking place virtually Wednesday, May 25, from 11:30 am to 3:30 pm. Each of the 12 companies have developed innovative technologies with the help of SBIR grants.

“Every day, in communities across America, entrepreneurs are solving our nation’s most pressing challenges from climate change to feeding and healing the world. The SBA is committed to helping ensure that those ideas receive the necessary support from federal programs and innovation ecosystems so that they can commercialize and grow into resilient businesses,” says Administrator Isabella Casillas Guzman in a news release.

“With the launch of America's Seed Fund Expo, we will showcase exceptional entrepreneurs who have leveraged federal research and development funding through the SBIR Program in key industries and connect them to resources to advance their game-changing innovations right here in America,” she continues.

Houston-based Re:3D is among the companies selected to present at the expo. The complete list of participating companies is as follows:

  • AgTech and Food Security
    • General Probiotics (Saint Paul, MN)
    • Nucleic Sensing Systems (Saint Paul, MN)
    • Shellfish Solutions d/b/a Blue Trace (Castine, ME)
  • Climate and Energy
    • Amorphic Tech (Allentown, PA)
    • FGC Plasma Solutions (Middleton, MA)
    • Hydroplane (Lancaster, CA)
  • National Security and Defense
    • BadVR (Pacoima, CA)
    • Enduralock (Lenexa, KS)
    • PSYONIC (Champaign, IL)
  • Supply Chain Resiliency
    • Chromatic 3D Materials (Golden Valley, MN)
    • Delta Development Team (Tucson, AZ)
    • Re:3D (Houston, TX)

“The giants of future industries so often start as small business startups with big ideas," says Bailey DeVries, associate administrator of the office of investment and innovation, in the news release. "We know the public and private sectors must work together to nurture these small businesses with big ideas over many years so they may sustain and grow. America’s Seed Fund Startup Expo will lift up big ideas and provide a platform for our national innovation community to support the businesses of tomorrow."

The event is free to attend virtually, and anyone can register online at https://bit.ly/SeedFundExpoRSVP. The America’s Seed Fund is among the Small Business Innovation Research and Small Business Technology Transfer programs and is collaborates with 11 federal agencies, that collectively support more than $4 billion a year in federal research and development funding.

Houston-based PolyVascular has invented a polymer-based heart valve for children with congenital heart disease. Photo courtesy of TMC Innovation

Houston startup with life-saving innovation receives $2M grant

for the children

A $2 million federal grant will enable Houston-based PolyVascular to launch human trials of what it hails as the first polymer-based heart valve for children.

In conjunction with the grant, Dr. Will Clifton has joined the medical device company as chief operating officer. He will oversee the grant as principal investigator, and will manage the company's operations and R&D. Clifton is president and co-founder of Houston-based Enventure, a medical innovation incubator and education hub. He previously was senior director of medical affairs at Houston-based Procyrion, a clinical-stage medical device company.

PolyVascular's Phase II grant came from the Small Business Innovation Research (SBIR) program, which promotes technological projects.

The PolyVascular heart valve will help treat congenital heart disease affecting more than 1 million around the world. PolyVascular plans to launch clinical trials of the valve in children 5 and over within two years.

"Congenital heart disease remains the most common category of birth defect and a leading cause of childhood death in the developed world," reads a March 30 news release from PolyVascular, founded in 2014.

PolyVascular says the valve can be implanted without surgery, and can avoid the use of valve replacements from humans or animals. Those valve replacements are difficult to find and often don't last too long, leading to frequent follow-up surgeries.

"Our aim at PolyVascular is to transform the care of children with congenital heart disease by developing an entirely new generation of valves made of medical-grade polymer devoid of any biological tissue," Dr. Henri Justino, chief medical officer at PolyVascular, says in a release. "The valves in use so far for children have been made of biological tissue. Unfortunately, our immune systems target and destroy this biological tissue, sometimes rapidly, rendering the valve ineffective."

The SBIR grant isn't the only win for PolyVascular in recent years.

In 2019, the startup came away with several honors in the 2019 Texas A&M New Ventures Competition. It won the pitch competition (complete with a $5,000 cash award), and received the Biotex Investment Prize, Amerra Visualization Services Prize, and GOOSE Society Investment Prize.

Also in 2019, PolyVascular, a member of TMCx's 2017 medical device cohort, won in the medical device and health disparities and equity categories at the fifth annual Impact Pediatric Health pitch competition. Additionally, the Southwest National Pediatric Device Consortium granted the company up to $25,000.

Last year, MedTech Innovator, a nonprofit accelerator in the medical technology sector, announced PolyVascular was one of 50 companies chosen to participate in the organization's flagship four-month accelerator program.

"During these uncertain and challenging times, the need for health innovations — specifically those that promise to deliver long-term value to the health care system and patients — is more critical than ever," said Paul Grand, CEO of MedTech Innovator.

Another Houston startup, Vivante Health, also was picked for the MedTech Innovator program. Vivante is a digital health company that helps people address digestive health and wellness.

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Houston robotics co. closes series B after year of growth

money moves

Houston- and Boston-based Square Robot Inc. closed a series B round of funding last month.

The advanced submersible robotics company raised $13 million, according to Tracxn.com, and says it will put the funds toward international expansion.

"This Series B round, our largest to date, enables us to accelerate our growth plans and meet the surging global demand for our services,” David Lamont, CEO, said in a statement.

The company aims to establish a permanent presence in Europe and the Middle East and grow its delivery services to reach four more countries and one new continent in Q1 2025.

Additionally, Square Robot plans to release a new robot early next year. The robot is expected to be able to operate in extreme temperatures up to 60 C. The company will also introduce its first AI-enabled tools to improve data collection.

Square Robot launched its Houston office in 2019. Its autonomous, submersible robots are used for storage tank inspections and eliminate the need for humans to enter dangerous and toxic environments.

The company was one of the first group of finalists for the Houston Innovation Awards' Scaleup of the Year, which honors a Bayou City company that's seen impressive growth in 2024. Click here to read more about the company's growth.

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This article originally ran on EnergyCapital.

Show me the money: Top Houston innovation grant and gift news of 2024

year in review

Editor's note: As the year comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. Money means a lot to startups and other innovative entities, and while startups are usually scouting venture capital investors, grants and donations are key too. These are the most-read news articles about grants and gifts — be sure to click through to read the full story.

Rice researchers secure $35M federal grant to advance medical device technology

Rice’s Biotech Launch Pad will lead the effort to commercialize the device. Photo courtesy Rice University

Rice University has secured part of a nearly $35 million federal grant aimed at commercializing a bioelectric implant for treatment of type 2 diabetes and obesity.

The federal Advanced Research Projects Agency for Health awarded the $34.9 million grant to Rice and several other universities.

Rice’s Biotech Launch Pad will lead the effort to commercialize the self-contained, implantable Rx On-site Generation Using Electronics (ROGUE) device. ROGUE houses cells that are engineered to produce type 2 diabetes and obesity therapies in response to patients’ needs. Continue reading.

Houston health care institutions receive $22M to attract top recruits

The grants, which are between $2 million to $6 million each, are earmarked for recruitment of prominent researchers. Photo via Getty Images

Houston’s Baylor College of Medicine has received a total of $12 million in grants from the Cancer Prevention & Research Institute of Texas to attract two prominent researchers.

The two grants, which are $6 million each, are earmarked for recruitment of Thomas Milner and Radek Skoda. The Cancer Prevention & Research Institute of Texas (CPRIT) announced the grants May 14.

Milner, an expert in photomedicine for surgery and diagnostics, is a professor of surgery and biomedical engineering at the Beckman Laser Institute & Medical Clinic at the University of California, Irvine and the university’s Chao Family Comprehensive Cancer Center. Continue reading.

New report ranks Houston top market for life sciences

Houston lands in the No. 7 spot for growth in the granting of degrees in biological and biomedical sciences. Photo by Natalie Harms/InnovationMap

Thanks in large part to producing hundreds of college-trained professionals, Houston’s life sciences industry ranks among the top U.S. markets for talent in 2024.

In a report published by commercial real estate services company CBRE, Houston lands in the No. 7 spot for growth in the granting of degrees in biological and biomedical sciences. From 2017 to 2022, Houston notched a growth rate of 32.4 percent in this category.

In 2022, the University of Houston led the higher education pack in the region, graduating 746 people with a bachelor’s degree or above in biological or biomedical sciences, according to the report. Continue reading.

Texas organization grants $68.5M to Houston institutions for recruitment, research

Several Houston organizations have received millions from the Cancer Prevention and Research Institute of Texas. Photo via tmc.edu

Three prominent institutions in Houston will be able to snag a trio of high-profile cancer researchers thanks to $12 million in new funding from the Cancer Prevention and Research Institute of Texas.

The biggest recruitment award — $6 million — went to the University of Texas MD Anderson Center to lure researcher Xiling Shen away from the Terasaki Institute for Biomedical Innovation in Los Angeles.

Shen is chief scientific officer at the nonprofit Terasaki Institute. His lab there studies precision medicine, including treatments for cancer, from a “systems biology perspective.” Continue reading.

Houston health care institution secures $100M for expansion, shares renderings

Baylor College of Medicine's Lillie and Roy Cullen Tower is set to open in 2026. Rendering courtesy of SLAM Architecture

Baylor College of Medicine has collected $100 million toward its $150 million fundraising goal for the college’s planned Lillie and Roy Cullen Tower.

The $100 million in gifts include:

  • A total of $30 million from The Cullen Foundation, The Cullen Trust for Health Care, and The Cullen Trust for Higher Education.
  • $12 million from the DeBakey Medical Foundation
  • $10 million from the Huffington Foundation
  • More than $45 million from members of Baylor’s Board of Trustees and other community donors, including the M.D. Anderson Foundation, the Albert and Margaret Alkek Foundation, and The Elkins Foundation.

“The Cullen Trust for Health Care is very honored to support this building along with The Cullen Foundation and The Cullen Trust for Higher Education,” Cullen Geiselman Muse, chair of The Cullen Trust for Health Care, says in a news release. “We cannot wait to see what new beginnings will come from inside the Lillie and Roy Cullen Tower.” Continue reading.

TMC launches cancer-focused partnership with Japan

global collaboration

Houston's Texas Medical Center announced the launch of its new TMC Japan BioBridge and Japan-Accelerator Cancer Therapeutics and Medical Devices, or JACT, this month.

The strategic partnership between Japan-based Mitsui Fudosan Co. Ltd. and the National Cancer Center will focus on advancing cancer treatments and providing a pathway for Japanese innovators to expand in the U.S. market. A delegation from TMC recently visited Tokyo, and William F. McKeon, president and CEO of TMC, signed the TMC Japan BioBridge Memorandum of Understanding with Takeshi Ozane, general manager of Mitsui Fudosan, and Hitoshi Nakagama, president of the National Cancer Center of Japan.

“The launch of TMC Japan BioBridge is a vital step forward in connecting two global leaders in healthcare innovation,” McKeon says in a statement. “Japan’s leadership has demonstrated an impressive commitment to advance medical cures and life sciences technologies and through this partnership, we are opening necessary doors for Japanese researchers and innovators to access the US market and collaborate with our TMC ecosystem. Together, we aim to accelerate critical breakthroughs to make a difference for patients all around the world.”

The new JACT will offer cancer-treatment companies a structured process to prepare for a U.S. expansion and will allow for meetings with pharmaceutical companies, hospital systems and investors and provide insights on U.S. regulatory approvals. It'll focus on three key areas, according to the statement:

  1. Milestone development and financial planning
  2. Clinical and regulatory expertise
  3. Strategic partnerships and market insights

“This TMC Japan BioBridge and JACT Program will enable us to promote the advancement of start-up companies aiming to commercialize innovative medical technologies originating in Japan into the U.S." Nakagama says in a statement. "We also hope this collaboration will not be limited to our (Japan Agency for Medical Research and Development)-supported project, but will lead to further cooperation between TMC, NCC, and other Japanese institutions in various fields.”

This is the sixth international strategic partnership for the TMC. It launched its first BioBridge, which focus on partnerships to support international healthcare companies preparing for U.S. expansion, with the Health Informatics Society of Australia in 2016. It also has BioBridge partnerships with the Netherlands, Ireland, Denmark and the United Kingdom.

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