Several Houston-area life science research teams receive thousands in grants

research roundup

It's pay day for several Houston-area research teams thanks to two grant programs. Photo via Getty Images

Several health innovation research teams across Houston are celebrating fresh funds to go toward the development of breakthrough technologies and research projects.

In InnovationMap's latest roundup of research news, check out who received this crucial funding and how their research and work can change the standard of care across the life science industry.

Reliant doles out $100,000 to two Houston Methodist critical care physician-scientists

Reliant announced that the recipients of the Reliant Innovation Fund will be two individuals within Houston Methodist Center for Critical Care in collaboration with Texas A&M's Engineering Medicine (EnMed) program.

"Meaningful innovation is core to us at Reliant and the work these institutions, physicians and students are doing is truly amazing," says Elizabeth Killinger, president of Reliant, in a news release. "We appreciate how Houston Methodist is making a lasting difference in our community by continuing to revolutionize medicine and we are honored to support them through the EnMed program."

Dr. Hina Faisal and Dr. Asma Zainab — along with the EnMed students who will support their work — will use the funds to advance their work. An anesthesiologist and critical care physician, Faisal will lead a project on 3-D-simulated virtual reality technology to prevent delirium in critically ill patients. Zainab, who specializes in cardiovascular ICU and focuses on respiratory failure and ventilator use, will lead a project to help personalize care in lung failure, creating models specific to each patient to avoid unnecessary pressure and injury caused by ventilators, per the release.

"Innovation is at the heart of what we do," says Dr. Faisal Masud, director of the Center of Critical Care at Houston Methodist, in the release. "Thanks to Reliant's generous contribution and ongoing support, we are able to seek out new ways to provide the best quality care for our most vulnerable patients while supporting our physicians, our students and their research."

Researchers at Rice University and Texas Medical Center institutions snag grants

Six research teams have received funding from Rice University's Educational and Research Initiatives for Collaborative Health, known as ENRICH. Established in 2016, the program focuses on connecting Rice faculty with TMC institutions to encourage collaboration. Last year, more than a fifth of Rice faculty were engaged in active collaborations with TMC research partners, according to a news release.

"Partnerships with TMC are an institutional priority, and they enable our faculty to translate their research to clinical practice, directly benefiting the Houston community," says Marcia O'Malley, special advisor to the provost on ENRICH and the Thomas Michael Panos Family Professor in Mechanical Engineering, in the release. "ENRICH has been instrumental in facilitating faculty engagement with TMC partners, reducing barriers to collaboration and investing institutional resources in new partnerships."

The Provost's TMC Collaborator Fund awarded $60,000 in grants to:

  • Jason Hafner '98, professor of physics and astronomy at Rice, and Carly Filgueira '09, assistant professor of nanomedicine and cardiovascular surgery at Houston Methodist Research Institute, to explore the development of an optical sensor for clinical detection of cholesterol.
  • Lan Li, assistant professor of history at Rice; Ricardo Ernesto Nuila, associate professor of medicine, medical ethics and health policy at Baylor College of Medicine; and Fady Joudah, a poet, literary translator and physician at Baylor St. Luke's Medical Center, for a pilot study of community health care access that addresses larger questions about medical racism in Houston.
  • Oleg Igoshin, professor of bioengineering at Rice, and Anna Konovalova, assistant professor of microbiology and molecular genetics at the University of Texas Health Science Center at Houston's McGovern Medical School, to explore new targets for antibiotic treatment by probing the feedback loop between two important stress-response pathways in bacteria.
Additionally, Rice ENRICH and Baylor's Interdisciplinary Surgical Technology and Innovation Center (INSTINCT) awarded $60,000 in grants to:
  • Pulickel Ajayan, the Benjamin M. and Mary Greenwood Anderson Professor in Engineering and chair of Rice's Department of Materials Science and Nanoengineering, and Crystal Shin, assistant professor of surgery at Baylor, for development of a self-charging, wireless microsensor capable of detecting changes in flow in blood vessels that have been replaced in heart bypass surgery.
  • Meng Li, Noah Harding Assistant Professor in Statistics at Rice, and Gabriel Loor, associate professor of surgery at Baylor, to study inflammation following lung transplantation and search for the cause of inflammatory responses that differ between men and women.
  • Vaibhav Unhelkar, assistant professor of computer science at Rice, and James Suliburk, associate professor of surgery at Baylor, to explore how artificial intelligence can augment surgical training.


The Equity Innovation Center Powered by Reliant will have online resources as well as an interactive learning lab at Tellepsen Family Downtown YMCA. Photo courtesy of Urban Land Institute Houston

YMCA of Greater Houston announces equity-focused innovation center backed by Reliant

it's fun to innovate at the

Houston is the most diverse city in the nation, and the YMCA of Greater Houston is looking to do its part to promote equity innovation by opening a new center.

The Equity Innovation Center Powered by Reliant will be the first of its kind in the region, and it will operate as a space for Houstonians to gather and collaborate.

"The YMCA of Greater Houston vows to stand with our brothers and sisters who are made to feel less safe by the many recent incidents – fighting for health equity in the face of the inequities being laid bare by the COVID-19 pandemic and unjust killings," says Stephen Ives, president and CEO, YMCA of Greater Houston, in a press release. "The Y will continue expanding and strengthening its commitment to combat racism, bias, prejudice and inequalities while fighting for justice."

The center will provide resources and activities so that visitors and collaborators can "walk away with a solid learning or unlearning" of social justice issues that are prominent in both Houston and nationally.

Rolling out in three phases, the project's first step is to foster conversations, consulting, and online trainings regarding systemic racial inequities. The next two phases will include setting up an interactive learning lab at Tellepsen Family Downtown YMCA, which would come to fruition by early next year.

The project is made possible by Reliant, a partner of the YMCA of Greater Houston.

"At Reliant, we respect, recognize and celebrate that our differences shape us, and that diversity and inclusion make us stronger. We're committed to powering change and supporting progress in the places where we live and work," says Elizabeth Killinger, president at Reliant, in the release. "By powering the Equity Innovation Center, we hope to further strengthen Houston so we can harness our full potential and make lasting change for future generations."

Reliant has donated $100,000 to the project, which will be distributed in $50,000 commitments over two years. The sum is a part of Reliant and NRG's "Powering Change" initiative, which has committed $1 million to go to organizations that combat racial inequities, injustice, and related violence, according to the release.

"We are grateful Reliant is joining our efforts to implement lasting and meaningful change within our community and beyond. We know that when we work as one, we move people and communities forward," Ives says.

Stephen Ives (left) is the president and CEO of YMCA of Greater Houston, and Elizabeth Killinger is president of Reiliant. Images courtesy

Reliant and Aramco Americas have provided Houston Methodist funds to move forward pertinent research and opportunities. Courtesy of Methodist Hospital/Facebook

2 corporations write checks to go toward Houston hospital's COVID-19 efforts

money moves

Two Houston companies have doled out cash to a Houston hospital's efforts in driving innovation during the pandemic as well as moving forward in a post-COVID-19 world.

Houston Methodist received $500,000 from Houston-based Aramco Americas and $130,000 from Houston-based Reliant. Aramco's gift will go toward funding ongoing research on convalescent plasma therapy as a treatment for COVID-19 and Reliant's donation will create the Reliant Innovation Fund.

"The challenges that we have and will continue to face with the COVID-19 pandemic amplifies the need for fresh ideas to combat this disease and treat those who have been affected," says Dr. Faisal Masud, medical director of the Center for Critical Care at Houston Methodist Hospital, in a news release from Reliant. "Innovating is at the core of what we do at Houston Methodist, and this generous gift from Reliant will make a difference for patients both now and for years to come."

According to the release, $100,000 will go toward supporting students in the Texas A&M University's Engineering Medicine program, which combines engineering and medical courses to allow for students to receive a master's in engineering and a medical degree in four years. Currently, A&M is renovating a building in the Texas Medical Center that will be the future home of the program.

"The EnMed program is educating a new type of physician — one with an engineering background and a forward-thinking, innovative medical mindset. Reliant's partnership and donation will allow our students to innovate for the dynamic needs on today's clinical front lines," says Dr. Timothy Boone, director of the Houston Methodist Education Institute and Associate Texas A&M Dean, in the release.

The other $30,000 of Reliant's gift will go towards expanding the hospital's patient-centric mobile app, CareSense, which Houston Methodist has used to connect with COVID-19 patients after they have left the hospital.

Aramco's donation will be used to support Houston Methodist's plasma research on COVID-19 treatment. The hospital was the first academic medical center in the United States to get FDA approval for this type of treatment on COVID-19 patients.

"Convalescent plasma therapy has been effective in other infectious diseases and our physician-scientists are working to develop it into a first-line treatment for COVID-19," says Dr. Dirk Sostman, president at the Houston Methodist Academic Institute, in a news release from Aramco.

The treatment collects blood from recovered COVID-19 patients and infuses the plasma into currently ill COVID-19 patients in hopes that the recovered patient's plasma can provide the antibodies for the ill patient to fight off the disease.

"Houston Methodist Hospital is a world-leader in healthcare as well as research and development," says Mohammad S. Alshammari, president and CEO of Aramco Americas in the release. "Our donation is an opportunity to support the innovative work occurring there in support of the Houston community and to contribute to long-term medical solutions for this global health crisis."

Midway's GreenStreet in downtown will be the site of MassChallenge Texas' Houston program. Photo via greenstreetdowntown.com

MassChallenge Texas announces the 26 companies in its inaugural Houston cohort

Startup studs

Since announcing its entrance into the Houston innovation market in January, MassChallenge Texas has been scoring the city — and the rest of the world — for the accelerator programs inaugural cohort. Now, the organization is ready to announce its 26 startups ahead of the program's July 22 launch.

The 26 companies come from three countries and six states, and half have female founders. The startups are mostly within the health care and high tech industries — eight companies reside in each of those categories. Two companies are energy related, and one company has a social impact focus. The remaining seven companies are categorized as "general," according to the release.

"We have an incredibly diverse cohort of startups for our first MassChallenge Texas in Houston program," says Jon Nordby, managing director of MassChallenge Texas in Houston, in the news release. "The startups cross five industries, where 50 percent of the startups come from outside of Houston bringing talent from innovation hubs like New York, San Francisco, and Switzerland. Proving that Houston's global reach is not just for the Fortune 500 and that startups are looking for their place in the global economy, something that Houston is uniquely suited to offer."

As a part of MassChallenge, the selected startups aren't asked for equity in order to participate, and free coworking space, more than $250K in deals and discounts, and more prizes await the top companies at the conclusion of the six-week programming.

Throughout the accelerator, MassChallenge will provide training, guidance, and corporate connections with a large network of companies, such as Southwest Airlines, TMAC, WeWork, USAA, Upstream, Central Houston, the City of Houston, Lionstone, Midway, BAE Systems, BHP, Ingram Micro, the San Antonio Spurs, and the Houston Texans. Houston-based Reliant, an NRG company, is the latest corporate partner to join those ranks, according to the release.

Over 280 companies applied for the program, says Robert Pieroni, director of economic development for Central Houston, in the release, a clear indication for him that the Houston program was a good decision for both the city and MassChallenge.

"When we set out to find a partner to support our innovation initiatives, we were seeking a catalyst for Houston's innovation ecosystem," Pieroni says in the release. "We knew we needed an organization that matched Houston's global reach and our passion for bringing creative ideas to life through business."

Without further adieu, here are the 26 companies that begin their MassChallenge journey on July 22:

  • AeroGenics (Iowa,)
  • AeroMINE (Texas,): AeroMINE is a motionless wind turbine created for the building environment. It installs like solar panels but is more cost effective.
  • Animatus Biosciences, LLC (Texas): Animatus Biosciences is an R&D company focusing on the development of unique regenerative therapeutics based on our modified mRNA platform.
  • Ask Doss (Texas): DOSS is a Real Estate Operations System (ReOS) that will radically simplify how people search (voice activated) and transact real estate.
  • Bell Analytics (Texas)
  • Bright Angle (Texas): Bright Angle is a Pinterest style activity platform for teachers, students, parents, and admins that is the "chalkboard" of the 21st century
  • Camppedia Inc. (Texas): Camppedia plans to disrupt the $18B children's camps industry and in the process improve the lives of millions of working parents.
  • Captain (Texas): Captain is a user-friendly, multi-sided platform that connects outdoor sports adventurers and guides.
  • Celise (Virginia): Celise is a compostable disposables company in the foodservice industry that aims to replace and eliminate single-use plastic waste.
  • Combined Arms [CAX-X] (Texas): Combined Arms is a forward-thinking nonprofit that is committed to unleashing the impact of veterans on Houston.
  • DoBrain (Republic of Korea): DoBrain is a children's diagnosis app that detects neuropsychological markers indicative of developmental delays.
  • Door Space Inc. (Texas): Door Space built a cloud-based platform that automates professional credential management and verification for clinicians and their employers.
  • ElecTrip (Texas): ElecTrip offers city-to-city, door-to-door transportation services in private-professionally driven Teslas with Wi-Fi and laptop charging. Book online to any major Texas-based city.
  • FloodFrame (Texas): FloodFrame is a concealed flood protection system that utilizes the natural buoyant force of water to deploy and protect your home.
  • Māk Studio (Texas): Māk Studio is a fabrication studio in the heart of Houston. We design and fabricate custom walls and furniture for commercial interiors.
  • NeuroRescue (Ohio): NeuroRescue improves the standard of care used to treat stroke, brain injury, and cardiac arrest to increase neurological outcome by up to forty-percent.
  • Noleus Technologies Inc. (Texas): Noleus is a novel medical device that reduces post op ileus, saves post op hospital days and accelerates patient recovery
  • ORDRS (Texas)
  • PTC Wizard (New York): PTC Wizard helps K-12 schools streamline their scheduling and sign-up process thereby improving parent involvement and decreasing overhead.
  • RehabMaker Corp. (California): Rehabmaker is a manufacturer of exercise equipment that attaches to wheelchairs and allows people to move their legs.
  • Reveal Technologies (Texas)
  • Sensytec Inc. (Texas): Sensytec is revolutionizing the oil & gas, and construction industries by bringing smart cement technologies and real-time data collection.
  • Swoovy (Texas): Swoovy is a mobile app that connects single people and volunteer opportunities with nonprofits, as a date.
  • Waterdata (Ticino, Switzerland): Waterdata offers Liquidprice, an Intelligent pricing software that optimizes prices with AI by adapting to customers, competitors and market behavior quickly.
  • WellWorth (Texas)
  • Zero5 (California)
Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Property Showcase

Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

View All Listings