The 130,000-square-foot Resilience Manufacturing Hub is coming to the Second Ward. Photo houston.org

A first-of-its-kind manufacturing hub designed to “future proof” residential, commercial, industrial, and public sector infrastructure is coming to Houston.

The 130,000-square-foot Resilience Manufacturing Hub will house functions such as R&D, manufacturing, and assembly for products aimed at improving the resilience of homes, office buildings, warehouses, and other components of the “built environment.”

“We are looking for any product or technology solution that can reduce the impact from the next generation of disasters … by helping people thrive, not just survive, in their own community,” says Richard Seline, co-founder and managing director of the Houston-based Resilience Innovation Hub. The innovation hub is a partner in the manufacturing hub.

Seline says the manufacturing hub, with an estimated price tag of $32 million, will directly employ about 60 people. He expects the facility to either generate or “upskill” about 240 off-site jobs.

The manufacturing hub will be built adjacent to the 300,000-square-foot East End Maker Hub, which is opened in Houston’s Second Ward neighborhood two years ago. Seline says five companies already have expressed interest in being tenants at the manufacturing hub, which is set to open by next summer.

The East End Maker Hub, a public-private endeavor, opened in the summer of 2021. Photo by Natalie Harms/InnovationMap

“We know that the supply chains keep failing over and over again in regard to responding to and rebuilding after disasters. This is a way to address that,” Seline says of the manufacturing hub.

Aside from the innovation hub and East End Maker Hub, partners in the manufacturing venture are the nonprofit Urban Partnerships Community Development Corp. (UPC) and modular construction company VEMAS. UPC is based in Houston, and VEMAS has a Houston office.

“The Resilience Manufacturing Hub is one of four pillars in UPC’s vision for an Invest Houston strategy to grow our economy from within by directly impacting middle-income employment — vital for the 1 million jobs projected as a gap in greater Houston’s long-term competitiveness,” says Patrick Ezzell, president and chairman of UPC and founder of the East End Maker Hub.

The manufacturing hub will work hand in hand with the innovation hub. The innovation hub assesses and addresses risks triggered by climate-produced, manmade, pandemic-related and cybersecurity threats. Hub participants work on innovations aimed at alleviating these risks.

In 2012, the National Academy of Sciences defined resilience as “the ability to prepare and plan for, absorb, recover from, and more successfully adapt to adverse events.” Those events include hurricanes and floods.

The resilience movement got a substantial boost last year thanks to passage of the federal Community Disaster Resilience Zones Act. The law allows for designation of resilience zones in communities that are at high risk of natural disasters and have limited resources. These zones will qualify for federal funding earmarked for resilience efforts.

Harris County scores nearly 98 out of 100 on the National Risk Index, generated by the Federal Emergency Management Agency (FEMA), putting it into the “very high” risk category for natural hazards.

Yet Harris County ekes out a score of 12.73 out of 100 for community resilience, landing it in the “very low” category. This means the county has a poor ability to prepare for natural hazards, adapt to changing conditions, and withstand and recover from disruptions.

Richard Seline is the co-founder and managing director of the Houston-based Resilience Innovation Hub. Photo courtesy

Six Houston startups — from health tech to aerospace — have moved into the new East End Maker Hub. Image courtesy of East End Maker Hub

New innovation hub grows with the addition of 6 Houston startups

moving in

The East End Maker Hub in Houston's East End District is growing with the recent addition of six startups.

"All of these companies cite the East End Maker Hub's physical innovation infrastructure, customizable spaces, strategic location, and potential collaborators as motivations for moving their operations into the hub," Patrick Ezzell, president of Urban Partnerships Community Development Corp., one of the hub's creators, says in an April 26 news release. "All are in the process of growing their teams and view Houston and, more specifically, the East End as a key resource for human capital heading into the future."

The companies that recently joined the East End Maker Hub are:

  • Alchemy Industrial. The company is a contract manufacturer that uses advanced technologies to develop industrial products for the medical, renewable energy, and drone sectors. Mush Khan, a British-born entrepreneur, established the startup last year.
  • CarbonATM. Led by Frank Zamarron and a group of former NASA engineers, CarbonATM aims to improve monitoring of ambient air quality with a low-cost portable device.
  • Gbowo Inc. This startup, founded in 2020, seeks to help companies reduce the environmental and financial costs of last-mile deliveries through the use of low-speed electrical vehicles. Ganiu Ladejobi is the founder and CEO.
  • Horizon Aeromarine. Established in 2020, the startup develops software and electronics from unmanned aerial and marine vehicles. Laura Sammons and Denver Hopkins are the founders.
  • Parallax 621. Founded by Benjamin Peters and Phillip Lentz, the Parallax 621 tech think tank develops technology based on theoretical physics research.
  • Polyvascular. The startup, established in 2014, makes a polymer-based heart valve for children with congenital heart disease.

The East End Maker Hub, at 6501 Navigation Blvd., is a collaboration between TXRX Labs and Urban Partnerships Community Development that houses crafters, fabricators, and tech manufacturers. TXRX Labs invested $1.25 million in equity to set up the hub. Urban Partnerships Community Development raised $35.75 million in capital to get the project off the ground.

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Houston doctor aims to revolutionize hearing aid industry with tiny implant

small but mighty

“What is the future of hearing aids?” That’s the question that led to a potential revolution.

“The current hearing aid market and technology is old, and there are little incremental improvements, but really no significant, radical new ideas, and I like to challenge the status quo,” says Dr. Ron Moses, an ENT specialist and surgeon at Houston Methodist.

Moses is the creator of NanoEar, which he calls “the world’s smallest hearing aid.” NanoEar is an implantable device that combines the invisibility of a micro-sized tympanostomy tube with more power—and a superior hearing experience—than the best behind-the-ear hearing aid.

“You put the NanoEar inside of the eardrum in an in-office procedure that takes literally five minutes,” Moses says.

As Moses explains, because of how the human cochlea is formed, its nerves break down over time. It’s simply an inevitability that if we live long enough, we will need hearing aids.

“The question is, ‘Are we going to all be satisfied with what exists?’” he asks.

Moses says that currently, only about 20 percent of patients who need hearing aids have them. That’s because of the combination of the stigma, the expense, and the hassle and discomfort associated with the hearing aids currently available on the market. That leaves 80 percent untapped among a population of 466 million people with hearing impairment, and more to come as our population ages. In a nearly $7 billion global market, that additional 80 percent could mean big money.

Moses initially patented a version of the invention in 2000, but says that it took finding the right team to incorporate as NanoEar. That took place in 2016, when he joined forces with cofounders Michael Moore and Willem Vermaat, now the company’s president and CFO, respectively. Moore is a mechanical engineer, while Vermaat is a “financial guru;” both are repeat entrepreneurs in the biotech space.

Today, NanoEar has nine active patents. The company’s technical advisors include “the genius behind developing the brains in this device,” Chris Salthouse; NASA battery engineer Will West; Dutch physicist and audiologist Joris Dirckx; and Daniel Spitz, a third-generation master watchmaker and the original guitarist for the famed metal band Anthrax.

The NanoEar concept has done proof-of-concept testing on both cadavers at the University of Antwerp and on chinchillas, which are excellent models for human hearing, at Tulane University. As part of the TMC Innovation Institute program in 2017, the NanoEar team met with FDA advisors, who told them that they might be eligible for an expedited pathway to approval.

Thus far, NanoEar has raised about $900,000 to get its nine patents and perform its proof-of-concept experiments. The next step is to build the prototype, but completing it will take $2.75 million of seed funding.

Despite the potential for making global change, Moses has said it’s been challenging to raise funds for his innovation.

“We're hoping to find that group of people or person who may want to hear their children or grandchildren better. They may want to join with others and bring a team of investors to offset that risk, to move this forward, because we already have a world-class team ready to go,” he says.

To that end, NanoEar has partnered with Austin-based Capital Factory to help with their raise. “I have reached out to their entire network and am getting a lot of interest, a lot of interest,” says Moses. “But in the end, of course, we need the money.”

It will likely, quite literally, be a sound investment in the future of how we all hear the next generation.

Houston VC funding surged in Q1 2025 to highest level in years, report says

by the numbers

First-quarter funding for Houston-area startups just hit its highest level since 2022, according to the latest PitchBook-NVCA Venture Monitor. But fundraising in subsequent quarters might not be as robust thanks to ongoing economic turmoil, the report warns.

In the first quarter of 2025, Houston-area startups raised $544.2 million in venture capital from investors, PitchBook-NVCA data shows. That compares with $263.5 million in Q1 2024 and $344.5 million in Q1 2023. For the first quarter of 2022, local startups nabbed $745.5 million in venture capital.

The Houston-area total for first-quarter VC funding this year fell well short of the sum for the Austin area (more than $3.3 billion) and Dallas-Fort Worth ($696.8 million), according to PitchBook-NVCA data.

While first-quarter 2025 funding for Houston-area startups got a boost, the number of VC deals declined versus the first quarters of 2024, 2023 and 2022. The PitchBook-NVCA Monitor reported 37 local VC deals in this year’s first quarter, compared with 45 during the same period in 2024, 53 in 2023, and 57 in 2022.

The PitchBook-NVCA report indicates fundraising figures for the Houston area, the Austin area, Dallas-Fort Worth and other markets might shrink in upcoming quarters.

“Should the latest iteration of tariffs stand, we expect significant pressure on fundraising and dealmaking in the near term as investors sit on the sidelines and wait for signs of market stabilization,” the report says.

Due to new trade tariffs and policy shifts, the chances of an upcoming rebound in the VC market have likely faded, says Nizar Tarhuni, executive vice president of research and market intelligence at PitchBook.

“These impacts amplify economic uncertainty and could further disrupt the private markets by complicating investment decisions, supply chains, exit windows, and portfolio strategies,” Tarhuni says. “While this may eventually lead to new domestic investment and create opportunities, the overall environment is facing volatility, hesitation, and structural change.”