A delegation from Houston consisting of former astronauts, aircraft experts, and local leaders were invited to the Paris Air Show to represent the Space City. Photo courtesy of the Greater Houston Partnership

Houston takes flight at Paris Air Show just in time for Space City Month​

Oui, oui

As we move closer to the 50th anniversary of Apollo 11 in mid-July, eyes around the world are turning to the United States and to Houston's NASA Johnson Space Center in celebration of the historic mission that first brought mankind to the moon. Thanks to that unprecedented interest, Houston was asked to be a featured partner of the USA Partnership Pavilion at the Paris Air Show last month.

Drawing nearly 2,500 exhibitors from 49 countries and more than 316,000 total visitors, the Paris Air Show continues to be the world's premier aerospace and aviation industry event. Houston's historic achievements set the stage to showcase how the region continues to be a global hub for technology and innovation.

A delegation of top Houston organizations brought distinct assets that showcased a collective advantage in competing for aerospace business. Led by the Greater Houston Partnership under the promotional banner Space City: The Gateway to Innovation, the group included:

  • Houston Spaceport, one of the nation's 10 licensed commercial spaceports co-located at Ellington Field (EFD).
  • Rice Space Institute, which has helped to establish Rice University's international reputation in all areas of space research by investing in efforts to further the development of new ideas and innovation in the broad area that is space exploration and utilization.
  • SpaceCom, the Space Commerce Conference and Exposition, an annual two-day conference that connects NASA technology with the private sector to fuel future innovation
  • Space Center Houston, the official visitor center of NASA's Johnson Space Center and a leading science and space learning center.
  • Blue Bear Capital, a Houston-based venture capital firm investing in fast-growing private companies that apply data driven technologies and innovative business models to the global energy supply chain.
  • Trumbull Unmanned, A Forbes Top 25 Veteran Founded startup based out of the Houston Spaceport that collects, analyzes, and visualizes critical data for the energy sector, primarily supporting oil and gas and environmental efforts.

As an anchor NASA community and home to the sharpest minds in aerospace, life sciences, energy and innovation, it was only fitting that Houston have a prominent presence in the show at Le Bourget. Among the 300 exhibitors representing the United States in the USA Partnership Pavilion, twenty of which were states, Houston was the only city with a major presence. Throughout the week, the Houston delegation participated in a schedule of high-profile thought-leadership and hospitality events to engage and educate global industry and government decision-makers and influencers.

For our part at the Greater Houston Partnership, we were able to conduct a series of meetings with companies from around the world, gathering more than 40 international and domestic economic development leads. The show is also a great media opportunity that allowed us to secure nearly 20 interviews for our delegation members with print and broadcast outlets from across the U.S. and Europe.

The USA Partnership Pavilion's week-long celebration of innovation and human achievement was led Apollo Astronauts Brig. Gen. Charlie Duke, and Houston-natives Col. Walt Cunningham and Col. Al Warden. Their presence served as a tangible way to connect our nation's achievements to the innovative future of the global aerospace industry.

"The 50th anniversary is such a unique time in history. It gives us an opportunity to think back about what we did, realize where we are today, and where we want to be in the future," says Col. Al Worden, "The most important thing about the space program was not so much about putting a man on the moon, it was about developing the technology to get there. Those technologies have made this country so successful, and I hope we continue to see that type of commitment to technology development in the future."

Houston delegates were asked to participate in several thought leadership panels.

"As we continue to explore further into the universe, there are a myriad of technical challenges that need to be overcome," says David Alexander, director of Rice Space Institute, who moderated a panel discussion on advancing technologies that will help humans physically and mentally adapt to deep space exploration. He was joined by industry leaders from United Launch Alliance (ULA), Lockheed Martin, Virgin Galactic, and Harris Corporation for the conversation centered around the use of artificial intelligence, 3D printing and additive manufacturing.

Governments around the globe including those in Europe, China and of course the United States have accelerated a discussion about sending humans back to the moon as a key step in our continued human exploration of deep space. This concept is also proving attractive to private companies, with an increase in public-private partnerships and a broader role being played by commercial entities in government aspirations.

Former astronaut and Space Station Commander turned venture capital leader Tim Kopra participated in a panel discussion on this very topic alongside representative from United Launch Alliance (ULA), the Federal Aviation Administration (FAA), Lockheed Martin, Deloitte, and the U.S. Air Force. Although Kopra's Blue Bear Capital's primary target are data-driven technologies in the energy industry, he notes that "there are a lot of intersections between energy and aerospace, and Houston's melting pot of global industries has turned the region into a hot bed for innovation with broader application of technologies."

The centerpiece of the Houston delegation's presence at the Paris Air Show was an executive briefing on June 19 featuring keynote remarks from Kopra that helped set the tone for the work Houston continues to do in innovation and aerospace technology. Kopra discussed his background with NASA, the transition into the funding scene that supports the region's growing innovation ecosystem, and what Houston has to offer businesses looking to expand their operations in the areas of aerospace, manufacturing, and digital technology.

A panel discussion followed, addressing topics that included educating the next generation of engineers and explorers, the intersection of NASA technology and the private sector, the next frontier of space exploration and the unique position that Houston has in pioneering those efforts.

"Over the past 58 years, Johnson Space Center has led the U.S. and the world in human exploration, discovery, and achievement in space," Kopra tells the audience. "Now we are in a position of transitioning a lot of those capabilities into the civilian sector."

The Houston Spaceport is one big step in that ongoing evolution. As the only commercial spaceport in the nation centered in a large metropolitan area, the Houston facility will have unmatched access to resources for companies and operators, said Arturo Machuca, general manager of the spaceport.

"The Houston Spaceport is being developed to ensure Houston stays relevant in commercial aerospace and aviation activities," he says. "Houston continues to hold a strong value proposition for companies looking to enter the aerospace industry with a unique set of advantages including the proximity to NASA's Johnson Space Center, unparalleled infrastructure through the Houston Airport System, and a strong talent base."

------

Josh Davis is the director of International Investment and Trade at the Greater Houston Partnership and organized the Partnership's participation at the Paris Air Show and gathered the delegation.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

---

This article first appeared on EnergyCapitalHTX.com.