This week's roundup of Houston innovators includes Joy M. Hutton of Joy of Consulting, Michael T. Suffredini of Axiom Space, and Kim Raath of Topl. Courtesy photos

Editor's note: In the last weekly roundup of Houston innovators of 2020, I'm introducing you to three innovators across the city — the new local leader of a new Google program, the CEO of a space tech company, and a startup founder with fresh funds.

Joy M. Hutton, local leader of Grow with Google's Digital Coach program

Joy M. Hutton leads the Grow with Google in Houston. Photo courtesy of Google

Joy M. Hutton is a serial entrepreneur and has just signed on to help guide other startup founders as the local leader of the Grow with Google Digital Coach program in Houston. Just like any other entrepreneur this year, Hutton, who was planning to launch her company On the Go Glam in March, was challenged to pivot her own startup amid COVID-19 and its accompanying obstacles.

On this week's episode of the Houston Innovators Podcast, Hutton shares how the pandemic caused her to rethink the timeline on some of the features she had in mind for the company.

"The pandemic was kind of a good thing, because it allowed me to take a step back and add additional services for men," Hutton says, adding that expanding into offering barbershop services was always a plan, but the new need pushed her to quickly pivot. Read more and stream the episode.

Michael T. Suffredini, president and CEO of Axiom Space

Michael T. Suffredini co-founded Houston-based Axiom Space. Photo via AxiomSpace.com

A veteran of the space business, Michael T. Suffredini now leads Axiom Space, which just announced a partnership with the Houston Spaceport. Mayor Sylvester Turner announced that Axiom Space will construct a 14-acre headquarters.

The headquarters "will be the world's first free-flying internationally available private space station that will serve as humanity's central hub for research, manufacturing, and commerce," Turner said.

The partnership is expected to bring more than 1,000 high-paying jobs, from engineers to scientists, mathematicians, and machinists. Read more.

Kim Raath, CEO of Topl

Kim Raath is ending her year with news of a VC deal. Courtesy of Topl

Unfortunately, the pandemic has had its detrimental effect on venture capital — especially when it comes to female-founded companies. Crunchbase reported a 27 percent decrease in funding for female-founded companies.

In light of this statistic, Kim Raath, CEO and co-founder of Houston-based Topl, is feeling pretty proud of leading her company to closing a $3 million round with support from investors both locally and across the country.

"We're grateful to have closed an oversubscribed venture round during a pandemic, especially given the unfortunate truth that many women-led startups are getting much less investment during this time," says Kim Raath, CEO of Topl, in a press release. "Bringing transparency to causes dedicated to environmental and social good has never been more important. We are building a modern blockchain for a world where purpose and profit go hand in hand." Read more.

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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

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Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.